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16篇 您的检索式:作者名="Fortún"
    题名 作者 年代 出处 被引量
1Tuberculosis in solid-organ transplant recipients:consensus statement of the group for the study of infection in transplant recipients (GESITRA) of the Spanish Society of Infectious Diseases and Clinical Microbiology显示文摘Aguado JM Torre-Cisneros J Fortún J 0,,09:1
2Tuberculosis in solid-organ transplant recipients:consensus statement of the group for the study of infection in transplant recipients(GESITRA)of the Spanish Society of Infectious Diseases and Clinical Microbiology显示文摘Aguado JM Torre-Cisneros J Fortún J 2009Clin Infect Dis2009,48,9:1
3Tuberculosis in solid-organ transplant recipients:consensus statement of the group for the study of infection in transplant recipients(GESITRA)of the Spanish Society of Infectious Diseases and Clinical Microbiology显示文摘Aguado JM Torre-Cisneros J Fortún J 2009Clin Infect Dis2009,48,9:1
4Analysis ofmortality and risk factors associated with native valve en-docarditis in drug users:the importance of vegetationsize显示文摘Martín-Dávila P Navas E Fortún J 2005Am Heart J2005,150,5:1
5Clinical validation of a multiplex real-time PCR assay for detection of invasive candidiasis in intensive care unit patients显示文摘Fortún J Meije Y Buitrago M J 2014Journal of Antimicrobial Chemotherapy2014,69,11:1
6Changes in the epidemiology of tuberculosis:the influence of international migration flows显示文摘Fortún J Martín-Dávila P Navas E 2011Enferm Infecc Microbiol Clin2011,29,9:1
7Epidemiology and outcome of infections in human immunodeficiency virus/hepatitis c virus-coinfected liver transplant recipients:A FIPSE/GESIDA Prospective Cohort Study显示文摘Moreno A Cervera C Fortún J 2012Liver transplantation2012,18,1:1
8Fungal infection in solid organ recipients显示文摘Fortún J Ruiz I Martín-Dávila P 0,,2:1
9Ca-125:a useful marker to distinguish pulmonary tuberculosis from other pulmonary infections显示文摘Fortún J Martín-Dávila P Méndez R 2009Open Respir Med J2009,,3:1
10Peliosis hepatis due to disseminated tuberculosis in a patient with AIDS显示文摘L. Sanz-Canalejas E. Gómez-Mampaso R. Cantón-Moreno C. Varona-Crespo J. Fortún F. Dronda 2014Infection2014,,1:1
11实体器官移植患者中热带病和地方性感染病的流行状况显示文摘Martín-Dávila P Fortún J López-Vélez R 康悦 吴菊芳 2010中国感染与化疗杂志2010,10,3:3
12Impacts of milkfish ( Chanos chanos ) aquaculture on carbon and nutrient fluxes in the Bolinao area, Philippines显示文摘Marianne Holmer Núria Marbá Jorge Terrados Carlos M. Duarte Mike D. Fortes 2002Marine Pollution Bulletin2002,,7:1
13Links between donor macrosteatosis,interleukin-33 and complement after liver transplantation显示文摘BACKGROUND As prevalence of nonalcoholic fatty liver disease increases in the population,livers with steatosis will continue to infiltrate the donor pool.Safe utilization of these extended criteria grafts is paramount given the increased risk associated with their use in transplantation.Prognostic factors that can predict liver dysfunction immediately after transplantation with macrosteatotic grafts are lacking.AIM To understand the relationship between interleukin-33(IL-33)and complement in recipients immediately following liver reperfusion as a marker of liver dysfunction.METHODS Cohort consisted of patients who received a liver transplant from September 2016–September 2019 at our institution.Clinical variables were retrospectively extracted from the electronic medical record.Back-table donor biopsies were obtained with donor steatosis percentage retrospectively determined by a boardcertified pathologist.Blood samples were available immediately following liver transplantation.Quantification of plasma IL-33 and complement proteins,C3a and C5a,were determined by enzyme-linked immunosorbent assay.For mRNA expression,RNA was extracted from donor biopsies and used against a 780 gene panel.RESULTS Cohort consisted of 99 donor and recipients.Donor median age was 45 years and 55%male.Recipients had a median age of 59 years with 62%male.The main etiologies were alcoholic hepatitis,nonalcoholic steatohepatitis,and hepatocellular carcinoma.Median MELD-Na at transplant was 21.Donors were grouped based on moderate macrosteatosis(≥30%).Recipients implanted with moderate macrosteatotic grafts had significantly higher peak alanine aminotransferase/aspartate aminotransferase(P<0.001 and P<0.004),and increased incidence of early allograft dysfunction(60%compared to 18%).Circulating IL-33 levels were significantly elevated in recipients of≥30%macrosteatotic grafts(P<0.05).Recipients with detectable levels of circulating IL-33 immediately following reperfusion had significantly higher alanine aminotransferase/aspartate aminotransferase(P<0.05 and P<0.01).Activated complement(C3a and C5a)were elevated in recipients implanted with moderate macrosteatotic grafts.RNA expression analysis of donor biopsies revealed moderate steatotic grafts upregulated genes inflammatory processes while downregulated hepatocyte-produced complement factors.CONCLUSION Circulating IL-33 and activated complement levels immediately following liver reperfusion in recipients of moderate macrosteatotic grafts may identify which patients are at risk of early allograft dysfunction.Kelley Núñez Mohammad Hamed Daniel Fort David Bruce Paul Thevenot Ari Cohen 2020World Journal of Transplantation2020,10,5:0
14Analysis of mortality and risk factors associated with native valve endocarditis in drug users: The importance of vegetation size显示文摘Pilar Martín-Dávila Enrique Navas Jesús Fortún Jose Luis Moya Javier Cobo Vicente Pintado Carmen Quereda Manuel Jiménez-Mena Santiago Moreno 2005American Heart Journal2005,,5:1
15Bacterial urinary tract infection after solid organ transplantation in the RESITRA cohort显示文摘E. Vidal J. Torre‐Cisneros M. Blanes M. Montejo C. Cervera J.M. Aguado O. Len J. Carratalá E. Cordero G. Bou P. Mu?oz A. Ramos M. Gurguí N. Borrell J. Fortún 2012Transpl Infect Dis2012,,6:1
16Infection with Nocardia Species: Clinical Spectrum of Disease and Species Distribution in Madrid, Spain, 1978–2001显示文摘V. Pintado E. Gómez-Mampaso J. Fortún M. A. Meseguer J. Cobo E. Navas C. Quereda P. Martín-Dávila S. Moreno 2002Infection2002,,6:1
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