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| 1 | Low-dose tacrolimus ameliorates liver inflammation and fibrosis in steroid refractory autoimmune hepatitis显示文摘AIM: To determine the eff icacy of tacrolimus on clinical status, histopathological status and biochemical markers in patients with steroid refractory autoimmune hepatitis (AIH). METHODS: Retrospectively, clinical parameters, biochemistry and histology were obtained from patient records. RESULTS: Nine patients [8 females/1 male, median age 32 (range 16-64) years] were identified to have received tacrolimus for a median duration of 18 (12-37) mo. Before initiation of tacrolimus treatment the patients were maintained on a prednisolone dose of 20 mg daily (range 20-80 mg/d), which was tapered to 7.5 (5-12.5) mg/d (P = 0.004). Alanine aminotransferase and immunoglobulin-G concentrations decreased from 154 (100-475) to 47(22-61) U/L (P = 0.007), and from 16 (10-30.2) to 14.5 (8.4-20) g/L (P = 0.032), respectively. All patients showed improvement of the liver inflammatory activity, as determined by the Ishak score (P = 0.016), while the degree of f ibrosis tended to decrease (P = 0.049). CONCLUSION: The use of low dose tacrolimus can lead to biochemical and histologic improvement of inflammation with no progression of the stage of f ibrosis in patients with steroid refractory AIH. Low dose tacrolimus therapy also allows substantial reduction of prednisone dose. | Fin Stolze Larsen Ben Vainer Martin Eefsen Peter Nissen Bjerring Bent Adel Hansen | 2007 | World Journal of Gastroenterology2007，13，23： | 15 |
| 2 | Effect of Prometheus liver assist system on systemic hemodynamics in patients with cirrhosis: A randomized controlled study显示文摘AIM: To evaluate treatment safety and hemodynamic changes during a single 6-h treatment with the Prometheus? liver assist system in a randomized, controlled study. METHODS: Twenty-four patients were randomized to either the study group or to one of two control groups: Fractionated Plasma Separation Adsorption and Dialysis, Prometheus? system (Study group; n = 8); Molecular Adsorbent Recirculation System (MARS)? (Control group 1, n = 8); or hemodialysis (Control group 2; n = 8). All patients included in the study had decompensated cirrhosis at the time of the inclusion into the study. Circulatory changes were monitored with a Swan-Ganz catheter and bilirubin and creatinine were monitored as measures of protein-bound and water-soluble toxins. RESULTS: Systemic hemodynamics did not differ between treatment and control groups apart from an increase in arterial pressure in the MARS group (P = 0.008). No adverse effects were observed in any of the groups. Creatinine levels significantly decreased in the MARS group (P = 0.03) and hemodialysis group (P = 0.04). Platelet count deceased in the Prometheus group (P = 0.04).CONCLUSION: Extra-corporal liver support with Prometheus is proven to be safe in patients with end- stage liver disease but does not exert the beneficial effects on arterial pressure as seen in the MARS group. | Thomas Dethloff Flemming Tofteng Hans-Jorgen Frederiksen Michael Hojskov Bent Adel Hansen Fin Stolze Larsen | 2008 | World Journal of Gastroenterology2008，14，13： | 4 |
| 3 | 低压冷喷涂铸造缺陷修复涂层性能研究显示文摘低压冷喷涂(LPCS)是一种拥有便携式冷喷涂系统的涂层技术。例如DYMET304K系统就应用于这项涂层技术中。通常情况下,压缩空气作为冷喷涂工艺中的运载气体。低压冷喷涂适用于喷涂金属基陶瓷复合粉末,如Cu基、Ni基、Zn基、Al基添加Al2O3粉的复合粉。硬质陶瓷相主要起到清洁喷嘴、增加表面活性和喷丸强化的作用,该方法在尺寸修复领域中具有优势。在这个领域里,修复铸造加工中的缺陷和气孔是一个很热门的应用。例如,Zn基复合材料就适用于防止电化学腐蚀和修复机械损伤造成的尺寸差异。本文对Zn+Al+Al2O3,Zn+Cu+Al2O3和Zn+Ni+Al2O3等复合材料做了实验研究。Zn和Al在腐蚀环境中起到阴极保护的作用,而Cu和Ni也有助于提高材料的机械性能。经过对微观孔蚀电位反应和力学性能(硬度和结合强度)的研究发现,涂层具有相对致密的结构和耐蚀性能。Zn在复合涂层中对其它金属起到阴极保护的作用。此外,在Fe52型铁基材料上的涂层有着足够的力学性能,硬度和结合强度较高。这一类涂层在修复宏观的铸造缺陷上具有很高的潜在应用价值。 | Koivuluoto H Kylmalahti M Vuoristo P Tampere/FIN 王旭 | 2012 | 热喷涂技术2012，4，1： | 3 |
| 4 | 中国铅合金冷却研究反应堆CLEAR-I概念设计研究[J]显示文摘 | 吴宜灿 FINS团队 | | 核科学与工程0，，： | 3 |
| 5 | Factors Associated With Response to Therapy and Outcome of Patients With Primary Biliary Cirrhosis With Features of Autoimmune Hepatitis显示文摘 | Ersan Ozaslan Cumali Efe Alexandra Heurgué–Berlot Taylan Kav Chiara Masi Tugrul Purnak Luigi Muratori Yücel Ustündag Solange Bresson–Hadni Gérard Thiéfin Thomas D. Schiano Staffan Wahlin Paolo Muratori | 2014 | Clinical Gastroenterology and Hepatology2014，，： | 3 |
| 6 | RESEARCH AND SIMULATION OF THE INFLUENCE OF THREE-AXIAL COMPACTION ON POWDER METALLURGIC PRODUCT PROPERTIES显示文摘温暖的粉末压缩过程被有限元素分析软件模仿, MSC/MARC。热机械地联合的分析方法根据更新的 Lagrangian 方法被使用,到模仿温暖的粉末压缩过程。温暖的粉末压缩过程被模仿,并且磨擦状况的影响和紧迫的式样在某些温度在粉末绿色和力学行为的密度上被研究。结果显示为圆柱的协议,与磨擦条件的改进,绿相对密度的分发的一致性是大部分改善了,紧迫的力量和应力减少,并且非一致压过程在某种程度上影响绿密度的分发。穿孔机第一最后压并且死的过程的压力分发的地位出版社与另外的三个过程不同,并且介绍‘ f lume' 的数字。 | D. G. Wang Y.C. Wu M.H. Jiao T.Xie J.W. Yu K G. Fin | 2008 | Acta Metallurgica Sinica(English Letters)2008，21，2： | 3 |
| 7 | Application of corrosion inhibitors for steels in acidic media for the oil and gas industry: A review显示文摘 | Matja? Fin?gar Jennifer Jackson | 2014 | Corrosion Science2014，，： | 2 |
| 8 | 国际脊髓损伤脊柱损伤基础数据集显示文摘收集脊柱损伤的信息对于脊髓损伤患者的诊断和治疗非常重要,设立脊髓损伤患者脊柱损伤基础数据集是为了规范脊柱损伤相关信息的收集方式和报告内容,学习并使用国际脊髓损伤脊柱损伤基础数据集,有助于规范和统一我国脊髓损伤患者脊柱损伤信息的收集,为相关治疗提供依据。本文将介绍国际脊髓损伤脊柱损伤基础数据集的研发过程,数据元素的内容以及数据编码的应用实例。 | Marcel F. Dvorak Peter C.Wing Michael G.Fehlings Alexander R. Vaccaro Eyal Itshayek Fin Biering-Sorensen Vanessa K.Noonan 王一吉(译) 周红俊(译) 李建军(译) 刘根林(译) 郑樱(译) 郝春霞(译) 张缨(译) 卫波(译) 康海琼(译) 逯晓蕾(译) | 2014 | 中国康复理论与实践2014，20，2： | 2 |
| 9 | Autoimmune hepatitis/primary biliary cirrhosis overlap syndrome and associated extrahepatic autoimmune diseases显示文摘 | Cumali Efe Staffan Wahlin Ersan Ozaslan Alexandra Heurgue Berlot Tugrul Purnak Luigi Muratori Chiara Quarneti Osman Yüksel Gérard Thiéfin Paolo Muratori | 2012 | European Journal of Gastroenterology & Hepatology2012，，5： | 2 |
| 10 | Shear-induced crystallization morphology and mechanical property of high density polyethylene in micro-injection molding显示文摘 | Xiang Lin Fin Caton-Rose Dongyun Ren Kuisheng Wang Phil Coates | 2013 | Journal of Polymer Research2013，，4： | 1 |
| 11 | The effect of preslanghter temperature,stress,struggle and anesthetization on color and texture characteristics of turkey muscle显示文摘 | Finning G W Babji A S Mather F B | 1978 | Poult Sci1978，57，： | 1 |
| 12 | Lumbar nerve root occupancy inthe for'amen in achondroplasia:a morphometric analysis显示文摘 | Modi FIN Sub SW Song HR | 2008 | ClinOrthop2008，4664，： | 1 |
| 13 | A New Method for the Analysis of Deformation and Load in a Ball Bearing with Variable Contact Angle显示文摘 | Neng Tung Liao Jen Fin Lin | | Transactions of the ASME0，，123： | 1 |
| 14 | Brain expression of the water channels Aquaporin-1 and -4 in mice with acute liver injury, hyperammonemia and brain edema显示文摘 | Martin Eefsen Peter Jelnes Lars E. Schmidt Ben Vainer Hanne Cathrine Bisgaard Fin S. Larsen | 2010 | Metabolic Brain Disease2010，，3： | 1 |
| 15 | Inter-active Computing on Wheels 显示文摘 | TSCHKLIGI M MESCHTSCHERJAK()V A WII FIN( ER I) | 2011 | Computer2011，44，8： | 1 |
| 16 | Service Quality Evaluation Models Determined by Online Consumer Perception and Satisfacion显示文摘 | Maria-Cristiana Munthiu Bogdan C fin Velicu Mihaela Tu Adina lulia Zara | 2014 | Procedia - Social and Behavioral Sciences2014，，12： | 1 |
| 17 | Autoregulation of Cerebral Blood Flow in Patients Resuscitated From Cardiac Arrest显示文摘 | Claus Sundgreen Fin Stolze Larsen Tina Maria Herzog Gitte Moos Knudsen Soren Boesgaard Jan Aldershvile | 2001 | Stroke: Journal of the American Heart Association2001，，1： | 1 |
| 18 | Time-of-flight MR angiography of the portal venous system:value compared with other imaging procedures显示文摘 | Hughes LA Hartnell GG Fin JP | 1996 | Am J Roentgenol1996，166，2： | 1 |
| 19 | Scuffing mechanism during oil-lubricated block-on-ring test with diamond nanoparticles as oil additive显示文摘 | Hsiao Yeh Chu Wen Chen Hsu Jen Fin Lin | 2010 | Wear2010，268，1112： | 1 |
| 20 | Use of maternal plasma for noninvasive determina- tion of real RhD status 显示文摘 | Harper T C Finning K M Martin P | 2004 | Am J Obste Gy- necol2004，191，5： | 1 |
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