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| 1 | U-Pb zircon age from the base of the Ediacaran Doushantuo Formation in the Yangtze Gorges,South China: constraint on the age of Marinoan glaciation显示文摘The reported new U-Pb age by sensitive high-resolution ion microprobe (SHRIMP Ⅱ) on zircon was obtained from a tuff sample at the basal Doushantuo Formation in the Jiuqunao section, which situated at the western limb of the Huangling anticline in the Yangtze Gorges in Zigui, Hubei, South China. Eighteen spots of zircons were analyzed and they form two clusters: one includes three spots, with an inherited age of 784+ 15 Ma (MSWD=0.05); the other consists of 15 spots and gives a weighted mean ^206pb/^238U age of 628.3±5.8 Ma (MSWD=0.86). It is the first SHRIMP U-Pb zircon age obtained nearly the base of the Doushantuo Formation of Ediacaran and represents a maximum age of the Doushantuo Formation It also forms an age constraint on the upper limit age of the Nantuo (Marinoantype) glaciation. | ChongyuYin FengTang YongqingLiu LinzhiGao PengjuLiu YushengXing ZhiqingYang YushengWan ZiqiangWang | 2005 | Episodes2005，28，1： | 57 |
| 2 | CT perfusion at early stage of hepatic diffuse disease显示文摘AIM: To determine the validity of the non-invasive method of CT perfusion (CTP) in rat model of hepatic diffuse disease. METHODS: Twenty-eight Wistar rats were divided into two groups. Liver diffuse lesions were induced by dietthylnitrosamine in 14 rats of test group. Rats in control groupwere bred with pure water. From the 1st to 12th wk after the test group was intervened, both groups were studied every week with CTP. CTP parameters of liver parenchymain different periods and pathologic changes in two groups were compared and analyzed.RESULTS: The process of hepatic diffuse lesions in test groups was dassified into three stages or periods according to the pathologic alterations, namely hepattitis, hepatic fibrosis, and cirrhosis. During this period, hepatic artery flow (HAF)of control group declined slightly, mean transit time (MTT),blood flow (BF) and volume (BV) increased, but there wereno significant differences between different periods. Tntest group, HAF tended to increase gradually, MTT prolonged obviously, BV and BF decreased at the same time. The results of statistical analysis revealed that the difference in the HAF ratio of test group to control group was significant.The ratio of BV and BF in test group to control group in stageof hepatitis and hepatic cirrhosis, hepatic fibrosis and early stage of hepatic cirrhosis was significantly different, but there was no significant difference between hepatitis and hepatic fibrosis. The main pathological changes in stage of hepatitis were swelling of hepatic cells, while sinusoid capillarization and deposition of collagen aggravated gradually in the extravascular Disse's spaces in stage of fibrosis and early stage of cirrhosis.CONCLUSION: The technique could reflect some early changes of hepatic blood perfusion in rat with liver diffuse disease and is valuable for their early diagnosis. | ShengGuan Wei-DongZhao Kang-RongZhou Wei-JunPeng JianMao FengTang | 2005 | World Journal of Gastroenterology2005，11，22： | 23 |
| 3 | EVALUATION OF EXTRACTS FROM BAMBOO FOR BIOLOGICAL ACTIVITY AGAINST CULEX PIPIENS PALLENS显示文摘The extracts from 7 species of bamboo were tested for larvicidal activity against Culex pipiens pallens. At the tested concentration, the extracts of selected bamboo had different degree of toxic effects on the fourth instar larvae of Culex pipiens pallens. Among them,the extracts of Pleioblastus juxianensis, Brachystachyum albostriatum, Phyllostachys platyglossa and Pleioblastus amarus were found to be effective with LC50values at 24h of 30.65mg/L,53.94mg/L, 41.21 mg/L and 54.49 mg/L respectively, against Culex pipiens pallens larvae. The extract of Pleioblastus juxianensis by Soxhlet method showed stronger activity than the extract obtained by interval-shaking, the LC50 of which were 30.65 mg/L and 48.34 mg/L, respectively.The diethyl ether extract of Pleioblastus juxianensis exhibited better larvicidal activity than the methanol extract and the petroleum ether extract. The results would help to provide the basis for the study of environment acceptable pesticide for mosquito control, and also help to comprehensively utilize the source of bamboo. | Hai-qunCao Yong-deYue Zhen-huaPeng Ri-maoHua FengTang | 2004 | Entomologia Sinica2004，11，4： | 6 |
| 4 | Construction,Characterization,and Chromosomal Mapping of a Fosmid Library of the White-Cheeked Gibbon (Nomascus leucogenys)显示文摘Gibbons have experienced extensive karyotype rearrangements during evolution and represent an ideal model for studying the underlying molecular mechanism of evolutionary chromosomal rearrangements. It is anticipated that the cloning and sequence characterization of evolutionary chromosomal breakpoints will provide vital insights into the molecular force that has driven such a radical karyotype reshuffle in gibbons. We constructed and characterized a high-quality fosmid li-brary of the white-cheeked gibbon (Nomascus leucogenys) containing 192,000 non-redundant clones with an average insert size of 38 kb and 2.5-fold genome coverage. By end sequencing of 100 randomly selected fosmid clones,we generated 196 se-quence tags for the library. These end-sequenced fosmid clones were then mapped onto the chromosomes of the white-cheeked gibbon by fluorescence in situ hy-bridization,and no spurious chimeric clone was detected. BLAST search against the human genome showed a good correlation between the number of hit clones and the number of chromosomes,an indication of unbiased chromosomal distribu-tion of the fosmid library. The chromosomal distribution of the mapped clones is also consistent with the BLAST search result against human and white-cheeked gibbon genomes. The fosmid library and the mapped clones will serve as a valu-able resource for further studying gibbons' chromosomal rearrangements and the underlying molecular mechanism as well as for comparative genomic study in the lesser apes. | Liping Chen Jianping Ye Yan Liu Jinghuan Wang Weiting Su Fengtang Yang Wenhui Nie | 2007 | Genomics, Proteomics & Bioinformatics2007，5，3： | 5 |
| 5 | The Canonical Correlation Analysis on Semen Quality and Serum Heavy Metals in Chinese Young Men显示文摘Objective To explore the correlation between serum heavy metal and semen quality in normal Chinese young menMethods This study was designed as a multi-center cross-sectional investigation. The subjects consisted of 562 male vomunteers who had undergone premarital physical examination in maternal and children health centers in 7 provinces in China.Results Results from Spearman rank correlation analysis (partial variable: region) show that serum lead and cadmium are negatively related to percentage of morphological normal sperm, but canonical correlation between semen quality and serum heavy metal are not significant. Canonical correlation analysis among the subjects from Guizhou shows cadmium is harmful to sperm morphology. In Henan, furthermore, results show lead and cadmium could negatively affect sperm viability and morphology.Conclusion Among all study subjects, canonical correlation between semen quality and serum heavy metal were not significant; however, results in some region showed serum cadmium and lead might be harmful to sperm quality. | Jun-qingWU Cui-lingLIANG Er-shengGAO Jian-guoTAO Qiu-yingYANG XiaoXU Wen-juanCAI JianGUO FengTANG JiangZHU Zhan-haiFU Yin-meiDU | 2003 | Journal of Reproduction and Contraception2003，14，2： | 2 |
| 6 | Invasive neuroendocrine carcinoma of the breast显示文摘 | BingWei TianDing YanXing WeiWei ZhenTian FengTang SusanAbraham KhaziNayeemuddin KellyHunt YunWu | 2010 | Cancer2010，，19： | 1 |
| 7 | Multicenter, Prospective, Randomized Safety and Efficacy Study of a New Atrial‐Based Managed Ventricular Pacing Mode (MVP) in Dual Chamber ICDs显示文摘 | MICHAEL O.SWEENEY KENNETH A.ELLENBOGEN DAVIDCASAVANT ROBERTBETZOLD TODDSHELDON FENGTANG MEGANMUELLER JOHNLINGLE | 2005 | Journal of Cardiovascular Electrophysiology2005，，8： | 1 |
| 8 | Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development显示文摘 | Philip J. Stephens Chris D. Greenman Beiyuan Fu Fengtang Yang Graham R. Bignell Laura J. Mudie Erin D. Pleasance King Wai Lau David Beare Lucy A. Stebbings Stuart McLaren Meng-Lay Lin David J. McBride Ignacio Varela Serena Nik-Zainal Catherine Leroy Mingm | 2011 | Cell2011，，1： | 1 |
| 9 | Multicenter, Prospective, Randomized Safety and Efficacy Study of a New Atrial‐Based Managed Ventricular Pacing Mode (MVP) in Dual Chamber ICDs显示文摘 | MICHAEL O.SWEENEY KENNETH A.ELLENBOGEN DAVIDCASAVANT ROBERTBETZOLD TODDSHELDON FENGTANG MEGANMUELLER JOHNLINGLE | 2005 | Journal of Cardiovascular Electrophysiology2005，，8： | 1 |
| 10 | Sensitive voltammetric determination of xanthinol nicotinate at a carbon nanotubes-ionic liquid gel modified electrode显示文摘The electrochemistry of xanthinol nicotinate(Xan) was studied by cyclic voltammetry at a glassy carbon electrode modified by a gel containing multi-walled carbon nanotubes(MWNTs) and room-temperature ionic liquid of 1-butyl-3-methylimidazolium hexafluorophosphate(BMTMPF_6).The modified electrode exhibited good promotion to the electrochemical oxidation of Xan and an ultrasensitive electrochemical method was proposed for the determination of Xan.This method was successfully applied to the determination of Xan in Xan tablets. | XiaoYu Bao Yu FengTang Hao Yang Xin Chen | 2009 | Chinese Chemical Letters2009，20，7： | 0 |
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