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| 1 | Different profile of cytokine synthesis according to the severity of acute pancreatitis显示文摘AIM: To evaluate the cellular synthetic ability of cytokines involved in pro- and anti-inflammatory reactions in patients with AP.METHODS: Sixty-seven patients with AP (16 severe,51 mild) and 10 controls were included in the study.Cultures of whole blood were performed in samples obtained within the first 72 h from the onset of pain.Serum levels of interleukins (IL) 6, 8, 10, and TNF-α were measured at baseline and in the supernatant of cultures with (functional reserve) or without stimulation with phytohemaglutinin.RESULTS: Basal levels of cytokines were significantly higher in patients with severe AP. A significant increase of all pro-inflammatory cytokines vs basal levels was observed in the supernatant after 24 h of whole blood cultures in patients, but not in controls. In contrast, IL-10 increased significantly in the supernatant of cultures only in patients with mild AP. Cells showed a statistically significant functional reserve for all IL in patients with mild, but only for pro-inflammatory cytokines in patients with severe AP.CONCLUSION: A marked activation of immune system may be observed in patients with AP, being balanced between pro- and anti-inflammatory cytokines in patients with mild but not severe AP. A reduced functional reserve for the synthesis of IL-10 may be observed in patients with severe AP, which might lead to a worst prognosis. | Raquel Laveda Juan Martínez Carlos Mu■oz Juan Carlos Penalva Jesus Sáez Germán Belda Salvador Navarro Faust Feu Anton Mas José Ma Palazón José Sánchez-Payá José Such Miguel Pérez-Mateo | 2005 | World Journal of Gastroenterology2005，11，34： | 24 |
| 2 | Risk of developing tuberculosis under anti-TNF treatment despite latent infection screening显示文摘 | Aranzazu Jauregui-Amezaga Fanny Turon Ingrid Ordás Marta Gallego Faust Feu Elena Ricart Julián Panés | 2012 | Journal of Crohn’s and Colitis2012，，： | 2 |
| 3 | A Multicenter, Randomized, Clinical Trial of Hormonal Therapy in the Prevention of Rebleeding From Gastrointestinal Angiodysplasia显示文摘 | Félix Junquera Faust Feu Michel Papo Sebastián Videla José Ramón Armengol Josep Mar??a Bordas Esteban Saperas Josep M. Piqué Juan-Ramón Malagelada | 2001 | Gastroenterology2001，，5： | 1 |
| 4 | From urban terrain models to visible cities显示文摘 | RIBARSKY W WASILEWSKI T FAUST N | 2002 | IEEE Computer Graphics and Applications2002，22，4： | 1 |
| 5 | The Virtual Reality of GIS显示文摘 | Faust N L | 1995 | Environment and Planning B:Planning and Design1995，，22： | 1 |
| 6 | Clinical events after transjugular intrahepatic portosystemic shunt: Correlation with hemodynamic findings显示文摘 | Marta Casado Jaume Bosch Juan Carlos García-Pagán Conxita Bru Rafael Ba?ares Juan Carlos Bandi Angels Escorsell José Manuel Rodríguez-Láiz Rosa Gilabert Faust Feu Carlos Schorlemer Antonio Echenagusia Joan Rodés | 1998 | Gastroenterology1998，，6： | 1 |
| 7 | CpG-depleted adeno-associated virus vectors evade immune detection显示文摘 | Faust Susan M Bell Peter Cutler Benjamin J Ashley Scott N Zhu Yanqing Rabinowitz Joseph E Wilson James M | 2013 | Journal of Clinical Investigation2013，，7： | 1 |
| 8 | Automated identification of normal and diabetes heart rate signals using nonlinear measures 显示文摘 | ACHARYA U R FAUST 0 KADIR N A | 2013 | Computers in biology and medicine2013，43，10： | 1 |
| 9 | Dysfunction of endothelial protein C activation in severe meningococcal sepsis显示文摘 | Faust S N Levin M Harrison O B | 2001 | N Engl J Med2001，345，6： | 1 |
| 10 | Testing multith-eoretical,multilevel hypotheses about organizational networks:an analytic framework and empirical example显示文摘 | Contractor N S Wasserman S Faust K | 2006 | Academy of Management Reveiw2006，31，3： | 1 |
| 11 | Testing Multitheoretical, Multilevel Hypotheses about Organizational Networks: An Analytic Framework and Empirical Example 显示文摘 | CONTRACTOR N S WASSERMAN S FAUST K | 2006 | Academy of Management Review2006，31，3： | 1 |
| 12 | Testing Multitheoretical Multilevel Hypotheses about Organizational Networks: An Analytical Framework and Empirical Example 显示文摘 | CONTRACTOR N S WASSERMAN S FAUST K | 2006 | Academy of Management Review2006，31，3： | 1 |
| 13 | An in vitro differentiation system for the examination of transgene activation in mouse macrophages显示文摘 | Faust N Bonifer C Wiles M V | 1994 | DNA Cell Biol1994，13，9： | 1 |
| 14 | Real-time, continuous level of detail rendering of height fields显示文摘 | LINDSTROM P KOLLER D RIBARSKY W HODGES L FAUST N and TURNER G | 1996 | Computer Graphics (SIGGRAPH ''96)1996，30，2： | 1 |
| 15 | Cytoplasmic vacuoles in renal tubular epithelium of mice given polyethylene glycol(PEG) conjugated protein are reduced by altering PEG size and conformation显示文摘 | Bolon B Faust J Storm N | | 0，，01： | 1 |
| 16 | 查看详情显示文摘 | Martinez-Castro N Lanzend(o)rfer M.G Müller A.H.E Cho J.C. Acar M.H.and Faust R | | 0，，： | 1 |
| 17 | Non-linear analysis of EEG signals at various sleep stages显示文摘 | Acharya UR Faust O Kannathal N | 2005 | Comput Methods Programs Biomed2005，80，1： | 1 |
| 18 | Right hemisphere sensitivity to novel metaphoric relations: Application of the signal detection theory显示文摘 | MASHAL N FAUST M | 2008 | Brain and Language2008，104，2： | 1 |
| 19 | Dysfunction of endothelial protein C activation in severe meningococcal sepsis 显示文摘 | FAUST S N LEVIN M HARRISON O B | 2001 | N Engl J Med2001，345，6： | 1 |
| 20 | The virtual reality of GIS 显示文摘 | Faust N L | 1995 | Environment and Planning B: Planning and Design1995，22，3： | 1 |
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