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250篇 您的检索式:作者名="Farrall"
    题名 作者 年代 出处 被引量
1胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
2Impact of lipoprotein(a) levels and apolipoprotein(a) isoform size on risk of coronary heart disease显示文摘J. C. Hopewell U. Seedorf M. Farrall S. Parish T. Kyriakou A. Goel A. Hamsten R. Collins H. Watkins R. Clarke 2014J Intern Med2014,,3:2
3Linkage of the angiotensin gene to essential hypertension 显示文摘Caulfield M Lavender P Farrall M 1994N Engl J Med1994,330,23:1
4Long-term subcutaneous pasireotide in an open-ended, multicenter, 显示文摘Petersenn S Farrall A J efficacy and safety of acromegaly: results from Phase II extension study 2013Pituitary2013,30,:1
5The effect of initial injec- tion conditions on the oil droplet motion in a simplified bearing chamber显示文摘Farrall M Hibberdl S Simmons K 2008Transactions of the ASME-Journal of Engi- neering for Gas Turbines and Power2008,130,1:1
6Changes in background blood-brain barrier integrity between lacunar and cortical ischemic stroke subtypes显示文摘Wardlaw JM Farrall A Armitage PA 2008Stroke2008,39,4:1
7A single amino acid difference distinguishes resistant and susceptible alleles of the rice blast resistance gene Pi-ta显示文摘Bryan G T Wu K S Farrall L 2000Plant Cell2000,12,11:1
8HLA has strongestassociation with IgA nephropathy in genome - wide studies 显示文摘Feehally J Farrall M Boland A 2010J Am Soc Nephrol2010,21,:1
9A numerical model for oil film flow in an aeroengine bearing chamber and comparison to ex- perimental data 显示文摘Farrall M Simmons K Hibberd S 2006Transactions of the ASME-Journal of Engineering for Gas Turbines and Power2006,128,1:1
10A single a-mino acid difference distinguish resistant and susceptible alleles of the rice blast resistance gene Pi-t显示文摘BRYAN GT WU KS FARRALL L 2000The Plant Cell2000,12,11:1
11Magnaporthe grisea Genes for Pathogenicity and Virulence Identified Through a Series of Backcrosses显示文摘VALENT B FARRALL L CHUMELY F G 1991Genetics1991,127,1:1
12Prediction of air/oil exit flows in a commercial aero-engine bearing chamber 显示文摘Farrall M Hibberd S Simmons K 2006Proceedings IMeehE Part G: Journal of Aerospace Engi- neering2006,220,:1
13Magnaporthe grisea genes for pathogenicity and virulence identified through a se- ries of baekcrosses 显示文摘VALENT B FARRALL L CHUMLEY F G 1991Genetics1991,127,:1
14A telomeric avirulence gene determines efficacy for the rice blast resistance gene Pi-ta显示文摘Orbach M J Farrall L Sweigard J A 2000Plant Cell2000,12,:1
15Impact of lipoprotein (a) levels and apolipoprotein (a) isoform size on risk of coronary heart disease 显示文摘Hopewell JC Seedorf U Farrall M 2014J Intern Med2014,276,3:1
16A telomeric avirulence gene determines efficacy for the rice blast resistance gene Pita 显示文摘Orbach M J Farrall L Sweigard J A 2000The Plant Cell2000,12,:1
17Genetic susceptibility to coronary artery disease: from promise to progress 显示文摘Watldns H Farrall M 2006Nat Rev Genet2006,7,3:1
18Magnaporthe grisca genes for pathogenicity and virulence identified through a series of backcrosscs显示文摘Valcnt B Farrall L Cuumley F G 1991Gcnctics1991,127,:1
19Genetic susceptibility to coronary artery disease: from promise to progress 显示文摘Watkins H Farrall M 2006Nat Rev Genet2006,7,3:1
20Prediction of air oil exit frows in a commercial acro-enginc bearing chamber 显示文摘Farrall M Hibberd S Simmons K 2006Journal of Aerospace Engineering2006,220,3:1
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