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17篇 您的检索式:作者名="Fanjun Chen"
    题名 作者 年代 出处 被引量
1Ideotype root architecture for efficient nitrogen acquisition by maize in intensive cropping systems显示文摘The use of nitrogen(N) fertilizers has contributed to the production of a food supply sufficient for both animals and humans despite some negative environmental impact.Sustaining food production by increasing N use efficiency in intensive cropping systems has become a major concern for scientists,environmental groups,and agricultural policymakers worldwide.In high-yielding maize systems the major method of N loss is nitrate leaching.In this review paper,the characteristic of nitrate movement in the soil,N uptake by maize as well as the regulation of root growth by soil N availability are discussed.We suggest that an ideotype root architecture for efficient N acquisition in maize should include(i) deeper roots with high activity that are able to uptake nitrate before it moves downward into deep soil;(ii) vigorous lateral root growth under high N input conditions so as to increase spatial N availability in the soil;and(iii) strong response of lateral root growth to localized nitrogen supply so as to utilize unevenly distributed nitrate especially under limited N conditions.MI GuoHua,CHEN FanJun,WU QiuPing,LAI NingWei,YUAN LiXing & ZHANG FuSuo* Key Laboratory of Plant Nutrition,MOA Key Laboratory of Plant-Soil Interaction,MOE College of Resources and Environmental Science,China Agricultural University,Beijing 100193,China 2010Science China(Life Sciences)2010,53,12:35
2Evaluation of the yield and nitrogen use efficiency of the dominant maize hybrids grown in North and Northeast China显示文摘Breeding high-yielding and nutrient-efficient cultivars is one strategy to simultaneously resolve the problems of food security,resource shortage,and environmental pollution.However,the potential increased yield and reduction in fertilizer input achievable by using high-yielding and nutrient-efficient cultivars is unclear.In the present study,we evaluated the yield and nitrogen use efficiency(NUE) of 40 commercial maize hybrids at five locations in North and Northeast China in 2008 and 2009.The effect of interaction between genotype and nitrogen(N) input on maize yield was significant when the yield reduction under low-N treatment was 25%-60%.Based on the average yields achieved with high or low N application,the tested cultivars were classified into four types based on their NUE:efficient-efficient(EE) were efficient under both low and high N inputs,high-N efficient(HNE) under only high N input,low-N efficient(LNE) under only low N input,and nonefficient-nonefficient under neither low nor high N inputs.Under high N application,EE and HNE cultivars could potentially increase maize yield by 8%-10% and reduce N input by 16%-21%.Under low N application,LNE cultivars could potentially increase maize yield by 12%.We concluded that breeding for N-efficient cultivars is a feasible strategy to increase maize yield and/or reduce N input.CHEN FanJun FANG ZenGuo GAO Qiang YE YouLiang JIA LiangLiang YUAN LiXing MI GuoHua ZHANG FuSuo 2013Science China(Life Sciences)2013,56,6:27
3Root growth in response to nitrogen supply in Chinese maize hybrids released between 1973 and 2009显示文摘Root growth has a fundamental role in nitrogen (N) use efficiency.Nevertheless,little is known about how modern breeding progress has affected root growth and its responses to N supply.The root and shoot growth of a core set of 11 representative Chinese maize (Zea mays L.) hybrids released between 1973 and 2009 were investigated under high N (4 mmol L?1,HN) and low N (0.04 mmol L?1,LN) levels in a solution culture system.Compared with LN,HN treatment decreased root dry weight (RDW),the root:shoot ratio (R/S),and the relative growth rate for root dry weight (RGRroot),but increased the total root length (TRL) and the total lateral root length (LRL).The total axial root length (ARL) per plant was reduced under HN,mostly in hybrids released before the 1990s.The number of seminal roots (SRN) was largely unaffected by different N levels.More recently released hybrids showed higher relative growth rates in the shoot under both HN and LN.However,the roots only showed increased RGR under HN treatment.Correspondingly,there was a positive linear relationship with the year of hybrid release for TRL,LRL and ARL under HN treatment.Together,these results suggest that while shoot growth of maize has improved,its root growth has only improved under high N conditions over the last 36 years of selective breeding in China.Improving root growth under LN conditions may be necessary to increase the N use efficiency of maize.WU QiuPing CHEN FanJun CHEN YanLing YUAN LiXing ZHANG FuSuo MI GuoHua 2011Science China(Life Sciences)2011,54,7:15
4The role of maize root size in phosphorus uptake and productivity of maize/faba bean and maize/wheat intercropping systems显示文摘Interspecific root/rhizosphere interactions affect phosphorus (P) uptake and the productivity of maize/faba bean and maize/wheat intercropping systems. The aim of these experiments was to determine whether manipulation of maize root growth could improve the productivity of the two intercropping systems. Two near isogenic maize hybrids (the larger-rooted T149 and smaller-rooted T222) were intercropped with faba bean and wheat, under conditions of high- and low-P availability. The larger-rooted T149 showed greater competitive ability than the smaller-rooted T222 in both maize/faba bean and maize/wheat intercropping systems. The higher competitive ability of T149 improved the productivity of the maize/faba bean intercropping system in P-sufficient conditions. In maize/wheat intercropping systems, root growth, shoot biomass, and P uptake of maize were inhibited by wheat, regardless of the P-supply. Compared with T222, the larger-rooted T149 suffered less in the intercropping systems. The total biomass of the maize/wheat intercropping system was higher for wheat/T149 than for wheat/T222 under low-P conditions. These data suggested that genetic improvement of maize root size could enhance maize growth and its ability to compete for P resources in maize/faba bean and maize/wheat intercropping systems. In addition, depending on the P availability, larger maize roots could increase the productivity of intercropping systems.ZHANG YiKai CHEN FanJun LI Long CHEN YanHua LIU BingRan ZHOU YuLing YUAN LiXing ZHANG FuSuo MI GuoHua 2012Science China(Life Sciences)2012,55,11:13
5Use of genotype-environment interactions to elucidate the pattern of maize root plasticity to nitrogen deficiency显示文摘Maize(Zea mays L.) root morphology exhibits a high degree of phenotypic plasticity to nitrogen(N) de ficiency,but the underlying genetic architecture remains to be investigated Using an advanced BC_4F_3 population,we investigated the root growth plasticity under two contrasted N levels and identi fied the quantitative trait loci(QTLs) with QTL-environment(Q×E)interaction effects. Principal components analysis(PCA) on changes of root traits to N de ficiency(D LN-HN) showed that root length and biomass contributed for 45.8% in the same magnitude and direction on the first PC,while root traits scattered highly on PC_2 and PC_3. Hierarchical cluster analysis on traits for D LN-HN further assigned the BC_4F_3 lines into six groups,in which the special phenotypic responses to N de ficiency was presented These results revealed the complicated root plasticity of maize in response to N de ficiency that can be caused by genotype environment(G×E) interactions. Furthermore,QTL mapping using a multi-environment analysis identi fied 35 QTLs for root traits. Nine of these QTLs exhibited signi ficant Q×E interaction effects. Taken together,our findings contribute to understanding the phenotypic and genotypic pattern of root plasticity to N de ficiency,which will be useful for developing maize tolerance cultivars to N de ficiency.Pengcheng Li Zhongjuan Zhuang Hongguang Cai Shuai Cheng Ayaz Ali Soomro Zhigang Liu Riliang Gu Guohua Mi Lixing Yuan Fanjun Chen 2016Journal of Integrative Plant Biology2016,58,3:8
6Enhancing phosphorus uptake efficiency through QTL-based selection for root system architecture in maize显示文摘Root system architecture(RSA) plays an important role in phosphorus(P) acquisition,but enhancing P use efficiency(PUE) in maize via genetic manipulation of RSA has not yet been reported.Here,using a maize recombinant inbred line(RIL) population,we investigated the genetic relationships between PUE and RSA,and developed P-efficient lines by selection of quantitative trait loci(QTLs) that coincide for both traits.In low-P(LP) fields,P uptake efficiency(Pup E) was more closely correlated with PUE(r =0.48-0.54),and RSA in hydroponics was significantly related to Pup E(r=0.25-0.30) but not to P utilization efficiency(Put E).QTL analysis detected a chromosome region where two QTLs for PUE,three for Pup E and three for RSA were assigned into two QTL clusters,Cl-bin3.04 a and Cl-bin3.04 b.These QTLs had favorable effects from alleles derived from the large-rooted and high-Pup E parent.Marker-assisted selection(MAS) identified nine advanced backcross-derived lines carrying Cl-bin3.04 a or Cl-bin3.04 b that displayed mean increases of 22%e26% in PUE in LP fields.Furthermore,a line L224 pyramiding Clbin3.04 a and Cl-bin3.04 b showed enhanced Pup E,relying mainly on changes in root morphology,rather than root physiology,under both hydroponic and field conditions.These results highlight the physiological and genetic contributions of RSA to maize Pup E,and provide a successful study case of developing P-efficient crops through QTL-based selection.Riliang Gu Fanjun Chen Lizhi Long Hongguang Cai Zhigang Liu Jiabo Yang Lifeng Wang Huiyong Li Junhui Li Wenxin Liu Guohua Mi Fusuo Zhang Lixing Yuan 2016Journal of Genetics and Genomics2016,43,11:3
7Identification of quantitative trait loci for leaf area and chlorophyll content in maize ( Zea mays ) under low nitrogen and low phosphorus supply显示文摘Hongguang Cai Qun Chu Lixing Yuan Jianchao Liu Xiaohui Chen Fanjun Chen Guohua Mi Fusuo Zhang 2012Molecular Breeding2012,,1:1
8Inhibition of maize root growth by high nitrate supply is correlated with reduced IAA levels in roots显示文摘Qiuying Tian Fanjun Chen Jinxin Liu Fusuo Zhang Guohua Mi 2007Journal of Plant Physiology2007,,9:1
9Evaluation of maize root growth and genome-wide association studies of root traits in response to low nitrogen supply at seedling emergence显示文摘Nitrogen(N) deficiency is one of the main factors limiting maize(Zea mays L.) productivity. Genetic improvement of root traits could improve nitrogen use efficiency. An association panel of 461 maize inbred lines was assayed for root growth at seedling emergence under high-nitrate(HN, 5 mmol L^(-1))and low-nitrate(LN, 0.05 mmol L^(-1)) conditions. Twenty-one root traits and three shoot traits were measured. Under LN conditions, the root-to-shoot ratio, root dry weight, total root length, axial root length,and lateral root length on the primary root were all increased. Under LN conditions, the heritability of the plant traits ranged from 0.43 to 0.82, a range much wider than that of 0.27 to 0.55 observed under HN conditions. The panel was genotyped with 542,796 high-density single-nucleotide polymorphism(SNP) markers. Totally 328 significant SNP markers were identified using either mixed linear model(MLM) or general linear model analysis, with 34 detected by both methods. In the 100-kb intervals flanking these SNP markers, four candidate genes were identified. Under LN conditions, the protoporphyrinogen IX oxidase 2 gene was associated with total root surface area and the DELLA protein-encoding gene was associated with the length of the visible lateral root zone of the primary root. Under HN conditions, a histone deacetylase gene was associated with plant height. Under both LN and HN conditions, the gene encoding MA3 domain-containing protein was associated with the first whorl crown root number. The phenotypic and genetic information from this study may be exploited for genetic improvement of root traits aimed at increasing NUE in maize.Xichao Sun Wei Ren Peng Wang Fanjun Chen Lixing Yuan Qingchun Pan Guohua Mi 2021The Crop Journal2021,9,4:1
10Rhizosphere effect and root growth of two maize ( Zea mays L.) genotypes with contrasting P efficiency at low P availability显示文摘Yan Liu Guohua Mi Fanjun Chen Jianhua Zhang Fusuo Zhang 2004Plant Science2004,,2:1
11Erythropoietin combined with granulocyte colony?stimulating factor enhancesMMP-2 expression in mesenchymal stem cells and promotes cell migration显示文摘Qiang Yu Long Chen Yong You Can Zou Youshun Zhang Qihuan Liu Fanjun Cheng 2011Molecular Medicine Reports2011,,1:1
12Integrated linkage mapping and genome-wide association study to dissect the genetic basis of zinc deficiency tolerance in maize at seedling stage显示文摘Zinc(Zn)deficiency is the most widespread micronutrient deficiency,affecting yield and quality of crops worldwide.Identifying genes associated with Zn-deficiency tolerance in maize is a basis for elucidating its genetic mechanism.A K22×CI7 recombinant inbred population consisting of 210 lines and an association panel of 508 lines were used to identify genetic loci influencing Zn-deficiency tolerance.Under-Zn and-Zn/CK conditions,15 quantitative trait loci(QTL)were detected,each explaining 5.7%-12.6%of phenotypic variation.Sixty-one significant single-nucleotide polymorphisms(SNPs)were identified at P<10^(-5)by genome-wide association study(GWAS),accounting for 5%-14%of phenotypic variation.Among respectively 198 and 183 candidate genes identified within the QTL regions and the 100-kb regions flanking these significant SNPs,12 were associated with Zn-deficiency tolerance.Among these candidate genes,four genes associated with hormone signaling in response to Zn-deficiency stress were co-localized with QTL or SNPs,including the genes involved in the auxin(ZmARF7),and ethylene(ZmETR5,ZmESR14,and ZmEIN2)signaling pathways.Three candidate genes were identified as being responsible for Zn transport,including ZmNAS3 detected by GWAS,ZmVIT and ZmYSL11 detected by QTL mapping.Expression of ZmYSL11 was up-regulated in Zn-deficient shoots.Four candidate genes that displayed different expression patterns in response to Zn deficiency were detected in the regions overlapping peak GWAS signals,and the haplotypes for each candidate gene were further analyzed.Jianqin Xu Zhongfu Ni Fanjun Chen Xiuyi Fu Futong Yu 2022The Crop Journal2022,10,6:0
13LDL receptor-related protein 1 (LRP1),a novel target for opening the blood-labyrinth barrier(BLB)显示文摘Inner ear disorders are a cluster of diseases that cause hearing loss in more than 1.5 billion people worldwide.However,the presence of the blood-labyrinth barrier(BLB)on the surface of the inner ear capillaries greatly hinders the effectiveness of systemic drugs for prevention and intervention due to the low permeability,which restricts the entry of most drug compounds from the bloodstream into the inner ear tissue.Here,we report the finding of a novel receptor,low-density lipoprotein receptor-related protein 1(LRP1),that is expressed on the BLB,as a potential target for shuttling therapeutics across this barrier.As a proof-ofconcept,we developed an LRP1-binding peptide,IETP2,and covalently conjugated a series of model small-molecule compounds to it,including potential drugs and imaging agents.All compounds were successfully delivered into the inner ear and inner ear lymph,indicating that targeting the receptor LRP1 is a promising strategy to enhance the permeability of the BLB.The discovery of the receptor LRP1 will illuminate developing strategies for crossing the BLB and for improving systemic drug delivery for inner ear disorders.Xi Shi Zihao Wang Wei Ren Long Chen Cong Xu Menghua Li Shiyong Fan Yuru Xu Mengbing Chen Fanjun Zheng Wenyuan Zhang Xinbo Zhou Yue Zhang Shiwei Qiu Liyuan Wu Peng Zhou Xinze Lv Tianyu Cui Yuehua Qiao Hui Zhao Weiwei Guo Wei Chen Song Li Wu Zhong Jian Lin Shiming Yang 2022Signal Transduction and Targeted Therapy2022,7,7:0
14QTL mapping and transcriptome analysis identify candidate genes influencing water–nitrogen interaction in maize显示文摘Water and nitrogen fertilization are the key factors limiting maize productivity.The genetic basis of interactions between maize genotype,water,and nitrogen is unclear.A recombinant inbred line(RIL)maize population was evaluated for seven yield and five agronomic traits under four water and nitrogen conditions:water stress and low nitrogen,water stress and high nitrogen,well-watered and low nitrogen,and well-watered and high nitrogen.Respectively eight,six,and six traits varied in response to genotype–water interactions,genotype–nitrogen interactions,and genotype–water–nitrogen interactions.Using a linkage map consisting of 896 single-nucleotide polymorphism markers and multipleenvironmental quantitative-trait locus(QTL)mapping,we identified 31 QTL,including 12 for genotype–water–nitrogen interaction,across the four treatments.A set of 8060 genes were differentially expressed among treatments.Integrating genetic analysis,gene co-expression,and functional annotation revealed two candidate genes controlling genotype–water–nitrogen interactions,affecting both leaf width and grain yield.Genes involved in abscisic acid biosynthesis and bZIP,NAC,and WRKY transcription factors participated in maize response to water and nitrogen conditions.These results represent a step toward understanding the genetic regulatory network of maize that responds to water and nitrogen stress and provide a theoretical basis for the genetic improvement of both water-and nitrogen-use efficiency.Kunhui He Yakun Zhang Wei Ren Pengyun Chen Jianchao Liu Guohua Mi Fanjun Chen Qingchun Pan 2023The Crop Journal2023,11,6:0
15THREE-DIMENSIONAL FINITE ELEMENT ANALYSIS AND ALLOWABLE DEFECT ASSESSMENT OF THE CENTRIFUGE BOWL BODY显示文摘For the first time,an allowable defect analysis of the bowl body of XZZ 1200-G Centrifuge was made by using fatigue fracture mechanics method;and,again for the first time,the design fatigue curve of the dangerous section of the bowl body was given out、which may form the basis for the design and use of the centrifuge.Xu Zhenxing Chen Fanjun Wang Zhaoqi Xu Yan Liu Yaodong Chen Yijun 1996Transactions of Nonferrous Metals Society of China1996,6,1:0
16Successful kidney transplantation in highly sensitized patients显示文摘Highly sensitized patients experience an increased number of rejection episodes and have poorer graft survival rates;hence,sensitization is a significant barrier to both access to and the success of organ transplantation.This study reports our experience in kidney transplantation in highly sensitized patients.Fourteen patients with sensitization or high levels of panelreactive antibodies(PRA)were studied.All patients were desensitized with pre-transplant intravenous immunoglobulin(IVIG)/plasmapheresis(PP)with or without rituximab and thymoglobulin induction therapy,combined with a Prograf/MMF/Pred immunosuppressive regimen.Of 14 patients,10 showed good graft functions without acute rejection(AR)episodes.Acute cellular rejection in two patients was reversed by methylprednisolone.Two patients underwent antibody-mediated rejection;one was treated with PP/IVIG successfully,whereas the other lost graft functions due to the de novo production of donor-specific antibodies(DSA).Graft functions were stable,and there were no AR episodes in other patients.Conclusively,desensitization using PP/IVIG with or without rituximab increases the likelihood of successful live-donor kidney transplantation in sensitized recipients.Weijie ZHANG Dong CHEN Zhishui CHEN Fanjun ZENG Changsheng MING Zhengbin LIN Ping ZHOU Gang CHEN Xiaoping CHEN 2011Frontiers of Medicine2011,5,1:0
17Genetic dissection of N use efficiency using maize inbred lines and testcrosses显示文摘Although the use of heterosis in maize breeding has increased crop productivity,the genetic causes underlying heterosis for nitrogen(N) use efficiency(NUE) have been insufficiently investigated.In this study,five N-response traits and five low-N-tolerance traits were investigated using two inbred line populations(ILs) consisting of recombinant inbred lines(RIL) and advanced backcross(ABL) populations,derived from crossing Ye478 with Wu312.Both populations were crossed with P178 to construct two testcross populations.IL populations,their testcross populations,and the midparent heterosis(MPH)for NUE were investigated.Kernel weight,kernel number,and kernel number per row were sensitive to N level and ILs showed higher N response than did the testcross populations.Based on a highdensity linkage map,138 quantitative trait loci(QTL) were mapped,each explaining 5.6%–38.8% of genetic variation.There were 52,34 and 52 QTL for IL populations,MPH,and testcross populations,respectively.The finding that 7.6% of QTL were common to the ILs and their testcross populations and that 11.7% were common to the MPH and testcross population indicated that heterosis for NUE traits was regulated by non-additive and non-dominant loci.A QTL on chromosome 5 explained 27% of genetic variation in all of the traits and Gln1-3 was identified as a candidate gene for this QTL.Genome-wide prediction of NUE traits in the testcross populations showed 14%–51% accuracy.Our results may be useful for clarifying the genetic basis of heterosis for NUE traits and the candidate gene may be used for genetic improvement of maize NUE.Xiaoyang Liu Kunhui He Farhan Ali Dongdong Li Hongguang Cai Hongwei Zhang Lixing Yuan Wenxin Liu Guohua Mi Fanjun Chen Qingchun Pan 2023The Crop Journal2023,11,4:0
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