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| 1 | Tandem catalysis in electrochemical CO_(2) reduction reaction显示文摘Electrochemical CO_(2) reduction reaction(CO_(2)RR)is an attractive pathway for closing the anthropogenic carbon cycle and storing intermittent renewable energy by converting CO_(2) to valuable chemicals and fuels.The production of highly reduced carbon compounds beyond CO and formate,such as hydrocarbon and oxygenate products with higher energy density,is particularly desirable for practical applications.However,the productivity towards highly reduced chemicals is typically limited by high overpotential and poor selectivity due to the multiple electron-proton transfer steps.Tandem catalysis,which is extensively utilized by nature for producing biological macromolecules with multiple enzymes via coupled reaction steps,represents a promising strategy for enhancing the CO_(2)RR performance.Improving the efficiency of CO_(2)RR via tandem catalysis has recently emerged as an exciting research frontier and achieved significant advances.Here we describe the general principles and also considerations for designing tandem catalysis for CO_(2)RR.Recent advances in constructing tandem catalysts,mainly including bimetallic alloy nanostructures,bimetallic heterostructures,bimetallic core-shell nanostructures,bimetallic mixture catalysts,metal-metal organic framework(MOF)and metal-metallic complexes,metal-nonmetal hybrid nanomaterials and copper-free hybrid nanomaterials for boosting the CO_(2)RR performance are systematically summarized.The study of tandem catalysis for CO_(2)RR is still at the early stage,and future research challenges and opportunities are also discussed. | Yating Zhu Xiaoya Cui Huiling Liu Zhenguo Guo Yanfeng Dang Zhanxi Fan Zhicheng Zhang Wenping Hu | 2021 | Nano Research2021，14，12： | 5 |
| 2 | Telomerase Activity in Condyloma Acuminatum Tissue with Different HPV Types显示文摘Summary: The telomerse activity in condyloma acuminatum (CA) tissue with human papillomavirus (HPV) types of 6/11 and 16/18 was detected to investigate the function of telomerase in the occurrence, development and carcinogenesis of genital CA. Forty-two biopsies from patients with gennital CA and 30 control tissue samples were tested for telomerase activity, HPV presence and types. The telomerase activity was determined by modified telomerase repeat amplification protocol (TRAP) assay and HPV typing by polymerase chain reaction (PCR) with typing-specific primers. Results showed that HPV-DNA was negative and the expression rate of telomerase was 16.7 % in all normal skin samples. All CA samples were positive for HPV (6/11 type was found in 32 cases, 16/18 in 3 and mixed type in 7). Telomerase activity was detectable in all CA patients. The telomerase activity in CA of 16/18 type was apparently higher than in CA of 6/11 type. It was concluded that the hyperplasia in CA might be increased as a result of HPV infection, suggesting that the activation of telomerase by HPV, especially by 16/18 type may play a role in the etiology and carcinogenesis of genital CA. | TU Yating (涂亚庭) CHEN Shanjuan(陈善娟) FAN Chao(樊超) LIN Nengxing(林能兴) LIU Houjun(刘厚君) LIU Zhixiabg(刘志香) | 2002 | Journal of Huazhong University of Science and Technology(Medical Sciences)2002，22，2： | 3 |
| 3 | Forest disturbances and the attribution derived from yearly Landsat time series over 1990–2020 in the Hengduan Mountains Region of Southwest China显示文摘Background:Natural forests in the Hengduan Mountains Region(HDMR)have pivotal ecological functions and provide diverse ecosystem services.Capturing long-term forest disturbance and drivers at a regional scale is crucial for sustainable forest management and biodiversity conservation.Methods:We used 30-m resolution Landsat time series images and the LandTrendr algorithm on the Google Earth Engine cloud platform to map forest disturbances at an annual time scale between 1990 and 2020 and attributed causal agents of forest disturbance,including fire,logging,road construction and insects,using disturbance properties and spectral and topographic variables in the random forest model.Results:The conventional and area-adjusted overall accuracies(OAs)of the forest disturbance map were 92.3% and 97.70%±0.06%,respectively,and the OA of mapping disturbance agents was 85.80%.The estimated disturbed forest area totalled 3313.13 km^(2)(approximately 2.31% of the total forest area in 1990)from 1990 to 2020,with considerable interannual fluctuations and significant regional differences.The predominant disturbance agent was fire,which comprised approximately 83.33% of the forest area disturbance,followed by logging(12.2%),insects(2.4%)and road construction(2.0%).Massive forest disturbances occurred mainly before 2000,and the post-2000 annual disturbance area significantly dropped by 55% compared with the pre-2000 value.Conclusions:This study provided spatially explicit and retrospective information on annual forest disturbance and associated agents in the HDMR.The findings suggest that China’s logging bans in natural forests combined with other forest sustainability programmes have effectively curbed forest disturbances in the HDMR,which has implications for enhancing future forest management and biodiversity conservation. | Yating Li Zhenzi Wu Xiao Xu Hui Fan Xiaojia Tong Jiang Liu | 2021 | Forest Ecosystems2021，8，4： | 2 |
| 4 | Inhibitory mechanism of angiotensin-converting enzyme inhibitory peptides from black tea显示文摘The aim of this work is to discover the inhibitory mechanism of tea peptides and to analyse the affinities between the peptides and the angiotensin-converting enzyme(ACE)as well as the stability of the complexes using in vitro and in silico methods.Four peptide sequences identified from tea,namely peptides I,II,III,and IV,were used to examine ACE inhibition and kinetics.The half maximal inhibitory concentration(IC_(50))values of the four peptides were(210.03±18.29),(178.91±5.18),(196.31±2.87),and(121.11±3.38)μmol/L,respectively.The results of Lineweaver-Burk plots showed that peptides I,II,and IV inhibited ACE activity in an uncompetitive manner,which requires the presence of substrate.Peptide III inhibited ACE in a noncompetitive manner,for which the presence of substrate is not necessary.The docking simulations showed that the four peptides did not bind to the active sites of ACE,indicating that the four peptides are allosteric inhibitors.The binding free energies calculated from molecular dynamic(MD)simulation were-72.47,-42.20,-52.10,and-67.14 kcal/mol(1 kcal=4.186 kJ),r espectively.The lower IC_(50)value of peptide IV may be attributed to its stability when docking with ACE and changes in the flexibility and unfolding of ACE.These four bioactive peptides with ACE inhibitory ability can be incorporated into novel functional ingredients of black tea. | Yating LU Yu WANG Danyi HUANG Zhuang BIAN Peng LU Dongmei FAN Xiaochang WANG | 2021 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2021，22，7： | 2 |
| 5 | Research on the ef- ficiency of querying historical data with the spatio-time data integration method 显示文摘 | Fan Yating Yang Jianyu Zhu Dehai | 2011 | Mathematical and Computer Model- ling2011，54，3： | 1 |
| 6 | Single-cell-resolution transcriptome map revealed novel genes involved in testicular germ cell progression and somatic cells specification in Chinese tongue sole with sex reversal显示文摘Female-to-male sex reversals(pseudomales)are common in lower vertebrates and have been found in natural populations,which is a concern under rapid changes in environmental conditions.Pseudomales can exhibit altered spermatogenesis.However,the regulatory mechanisms underlying pseudomale spermatogenesis remain unclear.Here,we characterized spermatogenesis in Chinese tongue sole(Cynoglossus semilaevis),a species with genetic and environmental sex determination,based on a highresolution single-cell RNA-seq atlas of cells derived from the testes of genotypic males and pseudomales.We identified five germ cell types and six somatic cell types and obtained a single-cell atlas of dynamic changes in gene expression during spermatogenesis in Chinese tongue sole,including alterations in pseudomales.We detected decreased levels of Ca^(2+)signaling pathway-related genes in spermatogonia,insufficient meiotic initiation in spermatocytes,and a malfunction of somatic niche cells in pseudomales.However,a cluster of CaSR genes and MAPK signaling factors were upregulated in undifferentiated spermatogonia of pseudomales.Additionally,we revealed that Z chromosome-specific genes,such as piwil2,dhx37,and ehmt1,were important for spermatogenesis.These results improve our understanding of reproduction after female-to-male sex-reversal and provide new insights into the adaptability of reproductive strategies in lower vertebrates. | Hong-Yan Wang Xiang Liu Jian-Yang Chen Yingyi Huang Yifang Lu Fujian Tan Qun Liu Mingming Yang Shuo Li Xianghui Zhang Yating Qin Wenxiu Ma Yingming Yang Liang Meng Kaiqiang Liu Qian Wang Guangyi Fan Rafael H.Nóbrega Shanshan Liu Francesc Piferrer Changwei Shao | 2023 | Science China(Life Sciences)2023，66，5： | 1 |
| 7 | Optimization and standardization of transient expression assays for gene functional analyses in strawberry fruits显示文摘Strawberry is increasingly used as a model plant for research on fruit growth and development.The transient gene manipulation(TGM)technique is widely used to determine the function of plant genes,including those in strawberry fruits.However,its reliable application for the precise identification of gene function has been difficult owing to the lack of conditional optimization.In this study,we found that successful transient gene manipulation requires optimization,with the vector type,temperature,and fruit developmental stage being three major factors determining success.Notably,we found that transient gene manipulation was feasible only from the large green fruit stage onwards,making it especially suitable for identifying genes involved in strawberry fruit ripening.Furthermore,we established a method called percentage difference of phenotype(PDP),in which the functional effect of a gene could be precisely and efficiently identified in strawberry fruits.This method can be used to estimate the functional effect of a gene as a value from 0 to 100%,such that different genes can be quantitatively compared for their relative abilities to regulate fruit ripening.This study provides a useful tool for accelerating research on the molecular basis of strawberry fruit ripening. | Yaoyao Zhao Wenwen Mao Yating Chen WeiWang Zhengrong Dai Zhechao Dou Kai Zhang Lingzhi Wei Tianyu Li Baozhen Zeng Ting Liu Yijuan Fan Jiaqi Yan Bingbing Li Wensuo Jia | 2019 | Horticulture Research2019，6，1： | 1 |
| 8 | Binary encoding-inspired generation of vector vortex beams显示文摘Vortex and vector terahertz(THz)beams with inhomogeneous polarization states have become a considerable hot topic in the last decade due to their important roles in multiplexed wireless data transmission.However,the technical instruments to form and evaluate such beams are rather limited,as they are mainly collected in the visible range.The emergence of coded metasurfaces has reinvigorated the design of functional devices with multiple degrees of freedom.Here,we demonstrate a versatile design inspired by a binary encoding approach for generating off-axis vectorial THz beams on all-silicon metasurfaces.Experimentally,simultaneous manipulation of the encoding method within the orthogonal circularly polarized(CP)channel provides strong support for developing versatility in vector THz beams,including the generation of arbitrary polarization profiles and the directional emission of multiplexed vector vortex beams(VVBs)with specified polarization states.The introduction of the latitudinal polarization control factor guarantees that continuously rotating or independently designed vector polarization profiles can be obtained on a pre-defined focal plane.Subsequently,a universal parametric theoretical model is developed to analyze the evolutionary trend of off-axis VVB in detail.Notably,the proposed monolayer vector metasurface bypasses the requirement of multiple cascaded optical elements,further inducing the advancement of ultra-thin vector THz sources,and also facilitating the generation of vector fields with tailored polarization distributions in 3D space. | Hui Li Chenglong Zheng Jingyu Liu Hang Xu Chunyu Song Fan Yang Jitao Li Zhen Yue Wei Shi Yating Zhang Yan Zhang Jianquan Yao | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，5： | 0 |
| 9 | Decay-like fracture diagnosis of composite insulator based on small sample virtual expansion and radar graph mapping显示文摘Due to the complexity of test procedures and the high cost of measurements,the mechanism of the decay-like fracture is unclear,which brings hard concepts and the small sample problem.Therefore,it is intractable to establish accurate data-driven models.To solve the above mentioned problems,this paper proposes a data-driven modeling method based on radar graph mapping models and virtual sample generation(Radar-VSG).The main idea of the proposed method is to construct and select the most appropriate input features by using radar graph mapping,and to generate virtual samples by using the local outlier factor based on the isometric feature mapping algorithm(Isomap-LOF).To verify the effectiveness of our approach,a set of 27 training samples and 127 testing samples from China Southern Power Grid was applied.Experimental results suggested the accuracy was up to 100%after adding more than 27 virtual samples,with a 4.75%improvement.And the model has the best generalisation ability for 270 virtual samples,with the root mean square error of 0.018.Compared with support vector machine and four advanced VSG methods,the proposed Radar-VSG can achieve better performance. | Ben Shang Youping Fan Yuqing Zhang Lei Yang Zijiang Wang Yating Zhang Zian Zeng Jianyi Guo | 2023 | High Voltage2023，8，2： | 0 |
| 10 | A review of passenger ride comfort in railway:assessment and improvement method显示文摘Passenger ride comfort has become a focus of attention in rail transportation equipment design,manufacture and later operation to meet people’s demand for travel quality.However,comfort is a very subjective concept,which is difficult to quantify and evaluate directly,and can be affected by various factors,leading to the corresponding technologies for ride comfort improvement becoming diverse.In this paper,recent research on the assessment method and improvement measures of railway passenger ride comfort is reviewed.The main types of ride comfort are summarized first according to the sources of discomfort,including static comfort,vibration comfort,noise comfort,aural pressure comfort,thermal comfort and visual comfort.The current assessment methods of ride comfort are introduced from the aspects of environmental parameters and human parameters based on the nature of evaluation indicators.Finally,the improvement technologies for each type of ride comfort are presented. | Yong Peng Jiahao Zhou Chaojie Fan Zhifa Wu Wenjun Zhou Dayan Sun Yating Lin Diya Xu and Qian Xu | 2022 | Transportation Safety and Environment2022，4，2： | 0 |
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