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| 1 | Benefit of combination β-blocker and endoscopic treatment to prevent variceal rebleeding: A meta-analysis显示文摘AIM: To determine whether the association of β-blockers with endoscopic treatment is superior to endoscopic treatment alone for the secondary prophylaxis of oesophageal variceal bleeding. METHODS: Randomised controlled trials comparing sclerotherapy (SCL) with SCL plus β-blockers (BB) or banding ligation (BL) with BL plus BB were identif ied.Main outcomes were overall and 6, 12 and 24 mo rebleeding rates, as well as overall and 6, 12 and 24 mo mortality. Two statistical methods were used: Yusuf-Peto, and Der Simonian and Laird. Inter-trial heterogeneity was systematically taken into account. RESULTS: Seventeen randomised controlled trials were included, 14 with SCL and 3 with BL. Combination β-blocker and endoscopic treatment signif icantly reduced rebleeding rates at 6, 12 and 24 mo and overall [odds ratio (OR): 2.20, 95% conf idence interval (CI): 1.69-2.85, P<0.0001] compared to endoscopic treatment alone. Mortality at 24 mo was signif icantly lower for the combined treatment group (OR: 1.83, 95% CI:1.16-2.90, P= 0.009), as well as overall mortality (OR: 1.43, 95% CI:1.03-1.98, P= 0.03). CONCLUSION: Combination therapy should thus be recommended as the fi rst line treatment for secondary prophylaxis of oesophageal variceal bleeding. | Natalie Funakoshi Frédérique Ségalas-Largey Yohan Duny Frédéric Oberti Jean-Christophe Valats Michael Bismuth Jean-Pierre Daurès Pierre Blanc | 2010 | World Journal of Gastroenterology2010，16，47： | 24 |
| 2 | Multidisciplinary management of acute mesenteric ischemia:Surgery and endovascular intervention显示文摘Acute mesenteric ischemia(AMI)is a rare cause of the“acute abdomen”,characterized by impaired blood flow to the intestine.The principle of treatment is restoration of perfusion to ischemic bowel and resection of any necrotic intestine.Surgery and endovascular intervention are two complementary approaches to mesenteric ischemia.Endovascular intervention is not an alternative to the surgical approach,but it has the potential to improve the prognosis of patients with AMI when judiciously combined with a surgical approach.Due to the need for emergent treatment of patients with acute mesenteric ischemia,the treatment strategy needs to be modified for each facility.This review aims to highlight cutting-edge studies and provide reasonable treatment strategies for patients with acute mesenteric ischemia based on available evidence. | Takashi Sakamoto Tadao Kubota Hiraku Funakoshi Alan Kawarai Lefor | 2021 | World Journal of Gastrointestinal Surgery2021，13，8： | 6 |
| 3 | Axitinib plus gemcitabine versus placebo plus gemcitabine in patients with advanced pancreatic adenocarcinoma: a double-blind randomised phase 3 study显示文摘 | Hedy L Kindler Tatsuya Ioka Dirk J Richel Jaafar Bennouna Richard Létourneau Takuji Okusaka Akihiro Funakoshi Junji Furuse Young Suk Park Shinichi Ohkawa Gregory M Springett Harpreet S Wasan Peter C Trask Paul Bycott Alejandro D Ricart Sinil Kim Eric Van | 2011 | Lancet Oncology2011，，3： | 4 |
| 4 | Foretinib (GSK1363089), a multi-kinase inhibitor of MET and VEGFRs, inhibits growth of gastric cancer cell lines by blocking inter-receptor tyrosine kinase networks显示文摘 | Yu Kataoka Toru Mukohara Hideo Tomioka Yohei Funakoshi Naomi Kiyota Yutaka Fujiwara Masakazu Yashiro Kosei Hirakawa Midori Hirai Hironobu Minami | 2012 | Investigational New Drugs2012，，： | 2 |
| 5 | Expressionof monocyte chemoattractant protein-1 by nonenzymatically glycated albumin (Amadori adducts) in vascular smooth muscle cells显示文摘 | Ichiki T Funakoshi Y Ito K | 2000 | Bioche Biophys Res Commun2000，269，： | 2 |
| 6 | Lack of Cholecystokinin-A Receptor Enhanced Gallstone Formation: A Study in CCK-A Receptor Gene Knockout Mice显示文摘 | Norikazu Sato Kyoko Miyasaka Shinji Suzuki Setsuko Kanai Minoru Ohta Takako Kawanami Yuki Yoshida Soichi Takiguchi Tetsuo Noda Yutaka Takata Akihiro Funakoshi | 2003 | Digestive Diseases and Sciences2003，，10： | 2 |
| 7 | Growth inhibition and apoptosis of RL human B lymphoma cells by vitamin E succinate and retinoic acid: role for transforming growth factor beta 显示文摘 | Turley JM Funakoshi S Ruseetti FW | 1995 | Cell Growth Differ1995，6，6： | 1 |
| 8 | Second-line chemoth- erapy for refractory small cell neuroendocrine carcinoma of the esophagus that relapsed after complete remission with irinotecan plus cisplatin therapy: Case report and review of the literature 显示文摘 | Funakoshi S Hashiguchi A Teramoto K | 2013 | Oncol Lett2013，5，1： | 1 |
| 9 | Extended operation for invasive thymoma with intracaval and intracardiac extension显示文摘 | FUNAKOSHI Y OHTA M MAEDE H | | 0，，02： | 1 |
| 10 | A systematic review of pre- dictive and prognostic biomarkers for VEGF-targeted therapy in renal cell carelnoma显示文摘 | Funakoshi T Lee CH Hsieh JJ | 2014 | Cancer Treat Rev2014，40，4： | 1 |
| 11 | Primary structure of human placental anticoagulant protein 显示文摘 | Funakoshi T Hendrickson L McMullen B | 1987 | Biochemistry1987，26，25： | 1 |
| 12 | 2-methoxyestradiol inhibits hypoxia-inducible factor-1 {alpha} and suppresses gruwth of lesions in a mouse model of endometriosis显示文摘 | Rohwer N Funakoshi T | 2008 | Am J Patbol2008，172，2： | 1 |
| 13 | Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons显示文摘 | Trupp M Ryden M Jomvall H Funakoshi H Timmusk T Arena S | 1995 | J Cell Biol1995，130，1： | 1 |
| 14 | G protein- coupled receptor 30 is an estrogen receptor in the plasma mem- brane 显示文摘 | FUNAKOSHI T YANAI A SHINODA K | 2006 | Biochem Biophys Res Commun2006，346，3： | 1 |
| 15 | Investigation of memory B cell responses to hepatitis B surface antigen in health care workers considered as non-responders to vaccination 显示文摘 | Valats JC Tuaillon E Funakoshi N | 2010 | Vaccine2010，28，： | 1 |
| 16 | Rotator cuff regeneration using chitin fabric an twellular matrix显示文摘 | Funakoshi T Majima T Suenaga N | 2006 | Shoulder Elbow Surg2006，15，1： | 1 |
| 17 | A systematic review of predic- tive and prognostic biomarkers for VEGF-targeted therapy in re- nal cell carcinoma显示文摘 | Funakoshi T CH Lee JJ Hsieh | 2014 | Cancer Treat Rev2014，40，4： | 1 |
| 18 | Comparative effects of chelating agents on pulmonary toxicity of systemic nickel in mice 显示文摘 | XIE J FUNAKOSHI T SHIMADA H | 1996 | J Appl Toxicol1996，16，4： | 1 |
| 19 | Ectopic Cdx2 expression in murine esophagus models an intermediate stage in the emergence of Barrett's esophagus显示文摘 | Kong J Crissey MA Funakoshi S | 2011 | PLoS One2011，6，18： | 1 |
| 20 | Histomorphometric analysis of age changes in the human inferior alveolar artery显示文摘 | Semba I Funakoshi K Kitano M | 2001 | Arch Oral Biol2001，46，1： | 1 |
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