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| 1 | Effects of electroacupuncture and Chinese kidney-nourishing medicine on polycystic ovary syndrome in obese patients显示文摘OBJECTIVE: To explore the effect of electroacupuncture and Chinese kidney-nourishing medicine on insulin (INS), adiponectin (APN), leptin (LEP), and glucolipid metabolism of obese patients with polycystic ovary syndrome (PCOS). METHODS: Sixty-seven obese PCOS patients were randomly divided into two groups. Thirty-three patients in the acupuncture-medicine group were treated three times a week with electroacupuncture at the Tianshu (ST 25), Zhongwan (CV 12), Qihai (CV 6), Sanyinjiao (SP 6), Geshu (BL 17), and Cil-iao (BL 32) acupoints. They also took the Chinese drug, Tiankui capsule, for 3 months as a course of treatment. Point-taking and treatment in the electroacupuncture group of 34 patients was the same as those in the acupuncture-medicine group. We observed and compared the changes in the obesity-related indexes of body weight (BW), body mass index (BMI), and waist-hip ratio (WHR), as well as fasting plasma glucose (FPG), fasting insulin (FINS), APN, and LEP. RESULTS: BW, BMI, WHR, and FINS decreased and insulin sensitivity index (ISI) and APN were higher in the acupuncture-medicine group than in the electroacupuncture group (P<0.01). There was no obvious difference in LEP between the two groups (P>0.05). CONCLUSION: Acupuncture combined with medicine is better than just electroacupuncture for obese PCOS patients by improving obesity-related indexes, insulin sensitivity, and APN level. This indicates that acupuncture-medicine therapy is worth clinical popularization. | Liqing Yu Yanjun Liao Huangan Wu Jimeng Zhao Luyi Wu Yin Shi Jianqiao Fang | 2013 | Journal of Traditional Chinese Medicine2013，33，3： | 15 |
| 2 | Distribution of stable carbon isotope in coalbed methane from the east margin of Ordos Basin显示文摘The commercial recovery of methane from coal is well established in the coalbed methane(CBM) blocks at the east margin of Ordos Basin, China. CBM forms with various carbon isotopic ratios(δ13CPDB) due to the carbon isotopic fractionation in biogenical or thermogenical processes. Based on the geologic evolution of coalbed reservoir and studies on the characteristics of δ13 CPDB values distributed spatially(e.g., horizontal CBM well location area, vertical coal burial zone, coal rank, etc.) and temporally(e.g., geologic evolution history), we explored the formation mechanism of carbon isotopic of methane. The relatively low δ13 CPDB values are widely distributed along the research area, indicating a trend of 'lighter-heavier-lighter' from north to south. From a combination analysis of the relationship between δ13 CPDB and the relative effects, the essential aspects in determining CBM carbon isotope being light in the study area are: the genesis of secondary biogas in the north; water soluble effects in the active hydrodynamic areas in the middle; desorption fractionation effect promoted by tectonic evolution in the south; and the sudden warming hydrocarbon fractionation accelerated by magmatic event in particular areas(e.g., Linxian). | LI Yong TANG DaZhen FANG Yi XU Hao MENG YanJun | 2014 | Science China Earth Sciences2014，57，8： | 6 |
| 3 | Temperature dependent Raman and photoluminescence of vertical WS2/MoS2 monolayer heterostructures显示文摘Heterostructures from two-dimensional transition-metal dichalcogenides MX_2 have emerged as a hot topic in recent years due to their various fascinating properties. Here, we investigated the temperature dependent Raman and photoluminescence(PL) spectra in vertical stacked WS_2/MoS_2 monolayer heterostructures. Our result shows that both E_(2g)~1 and A_(1g) modes of WS_2 and MoS_2 vary linearly with temperature increasing from 300 to 642 K. The PL measurement also reveals strong temperature dependencies of the PL intensity and peak position. The activation energy of the thermal quenching of the PL emission has been found to be equal to 69.6 meV. The temperature dependence of the peak energy well follows the bandgap shrinkage of bulk semiconductor. | Zhijian Hu Yanjun Bao Ziwei Li Yongji Gong Rui Feng Yingdong Xiao Xiaochun Wu Zhaohui Zhang Xing Zhu Pulickel M. Ajayan Zheyu Fang | 2017 | Science Bulletin2017，62，1： | 5 |
| 4 | Atomistic Surface Passivation of CH_(3)NH_(3)PbI_(3) Perovskite Single Crystals for Highly Sensitive Coplanar-Structure X-Ray Detectors显示文摘Organic-inorganic halide perovskites(OIHPs)are recognized as the promising next-generation X-ray detection materials.However,the device performance is largely limited by the ion migration issue of OIHPs.Here,we reported a simple atomistic surface passivation strategy with methylammonium iodide(MAI)to remarkably increase the ion migration activation energy of CH_(3)NH_(3)PbI_(3)single crystals.The amount of MAI deposited on the crystal surface is finely regulated by a self-assemble process to effectively suppress the metallic lead defects,while not introducing extra mobile ions,which results in significantly improved dark current stability of the coplanar-structure devices under a large electric field of 100Vmm^(-1).The X-ray detectors hence exhibit a record-high sensitivity above 700,000μC Gy^(-1)_(air) cm^(-2)under continuum X-ray irradiation with energy up to 50 keV,which enables an ultralow X-ray detection limit down to 1.5 nGy_(air)s^(-1).Our findings will allow for the dramatically reduced X-ray exposure of human bodies in medical imaging applications. | Yilong Song Liqi Li Weihui Bi Mingwei Hao Yifei Kang Anran Wang Zisheng Wang Hanming Li Xiaohui Li Yanjun Fang Deren Yang Qingfeng Dong | 2020 | Research2020，，1： | 5 |
| 5 | Numerical determination for optimal location of sub-track asphalt layer in high-speed rails显示文摘Well-graded asphalt mix with the merits of high sound absorption, low water permeability, excellent strength, and easy construction is an important option for high-speed railway substructures. On the basis of finite element method, a model with conventional ballasted trackbed (T0) and four ballasted trackbeds models with different positions of asphalt layer were analyzed, in which 15 cm thick asphalt layer was used to replace the different sub-track layers, the bottom and the top of upper subgrade and of ballasted trackbed, named as T1 , T2 , T3 , and T4 , respectively. The results showed that the range of peak vertical accelerations on the top of subgrade surface of T2 and T4 were smaller than T1 and T3 ; T1 and T2 perform better in decreasing the maximum vertical deformation of subgrade than T3 and T4 ; the maximum transversal tensile strain of T4 is almost twice than the other three. The trackbed bears more stress when the asphalt layer is located at the lower part of railway trackbed. | Mingjing Fang Sergio Fernández Cerdas Yanjun Qiu | 2013 | Journal of Modern Transportation2013，21，2： | 4 |
| 6 | Comparative analysis on dynamic behavior of two HMA railway substructures显示文摘A numerical analysis using a finite element program was performed on three structures:hot mix asphalt(HMA) reinforced trackbed(RACS-1),HMA directly supported trackbed(RACS-2),and traditional Portland Cement Concrete(PCC) slab track(SlabTrack).Although the comprehensive dynamic responses of RACS-1 were similar with SlabTrack,HMA layer can positively affect the stress distributions.In particular,the horizontal stresses indicate that the resilience of RACS-1 was improved relative to SlabTrack.In addition,HMA reinforced substructure has the capacity to recover the residual vertical deformation.The effective depth for weakening dynamic loadings is mainly from 0 to 2 m,this being especially true at 0.5 m.The results from the analysis show that HMA is a suitable material for the railway substructure to enhance resilient performance,improve the stress distribution,weaken dynamic loading,and lower the vibration,especially at the effective depth of 2 m.The HMA constructed at the top of the stone subbase layer allows the vertical modulus a smooth transition.In terms of the comprehensive dynamic behaviors,RACS-1 is better than SlabTrack,while the results for RACS-2 are inconclusive and require further research. | Mingjing FANG Yanjun QIU Jerry G. ROSE Randy C. WEST Changfa AI | 2011 | Journal of Modern Transportation2011，19，1： | 3 |
| 7 | Phase Ⅲ Clinical Trials of the Cell Differentiation Agent-2 (CDA-2): Therapeutic Efficacy on Breast Cancer, Non-Small Cell Lung Cancer and Primary Hepatoma显示文摘 | Fengyi Feng Qing Lu Changquan Ling Yang Zhang Fengzhan Qin Huaqing Wang Wenxia Huang Shunchang Jiao Qiang Chen Mingzhong Li Yunzhong Zhu Meizhen Zhou Jun Ren Yetao Gao Jingpo Zhao Rongsheng Zheng Wenhua Zhao Zhiqiang Meng Fang Li Qizhong Zhang Dongli Zhao Liyan Xu Yongqiang Zhang Yanjun Zhang Zhenjiu Wang Shuonqi Liu Ming C. Liau | 2005 | Chinese Journal of Clinical Oncology2005，2，4： | 3 |
| 8 | Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome显示文摘 | Yu Chen Weifeng Liang Shigui Yang Nanping Wu Hainv Gao Jifang Sheng Hangping Yao Jianer Wo Qiang Fang Dawei Cui Yongcheng Li Xing Yao Yuntao Zhang Haibo Wu Shufa Zheng Hongyan Diao Shichang Xia Yanjun Zhang Kwok-Hung Chan Hoi-Wah Tsoi Jade Lee-Lee Teng We | 2013 | 2013 (9881)2013，，9881： | 2 |
| 9 | PM_(2.5) exposure associated with microbiota gut-brain axis:Multi-omics mechanistic implications from the BAPE study显示文摘Recent studies have shown that PM_(2.5) may activate the hypothalamus-pituitary-adrenal(HPA)axis by inducing hormonal changes,potentially explaining the increase in neurological and cardiovascular risks.In addition,an association between PM_(2.5) and gut microbiota and metabolites was established.The above evidence represents crucial parts of the gut-brain axis(GBA).In view of this evidence. | Tiantian Li Jianlong Fang Song Tang Hang Du Liang Zhao Yanwen Wang Fuchang Deng Yuanyuan Liu Yanjun Du Liangliang Cui Wanying Shi Yan Wang Jiaonan Wang Yingjian Zhang Xiaoyan Dong Ying Gao Yu Shen Li Dong Huichan Zhou Qinghua Sun Haoran Dong Xiumiao Peng Yi Zhang Meng Cao Hong Zhi Jingyang Zhou Xiaoming Shi | 2022 | The Innovation2022，3，2： | 2 |
| 10 | Determination of daminozide in apple sample by mip-coated piezoelectric quartz sensor显示文摘 | YAN Shoulei FANG Yanjun GAO Zhixian | 2007 | Analytical Letters2007，40，6： | 1 |
| 11 | Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome显示文摘 | Yu Chen Weifeng Liang Shigui Yang Nanping Wu Hainv Gao Jifang Sheng Hangping Yao Jianer Wo Qiang Fang Dawei Cui Yongcheng Li Xing Yao Yuntao Zhang Haibo Wu Shufa Zheng Hongyan Diao Shichang Xia Yanjun Zhang Kwok-Hung Chan Hoi-Wah Tsoi Jade Lee-Lee Teng We | 2013 | The Lancet2013，，9881： | 1 |
| 12 | Multi-platform omics analysis reveals molecular signature for COVID-19 pathogenesis,prognosis and drug target discovery显示文摘Disease progression prediction and therapeutic drug target discovery for Coronavirus disease 2019(COVID-19)are particularly important,as there is still no effective strategy for severe COVID-19 patient treatment.Herein,we performed multi-platform omics analysis of serial plasma and urine samples collected from patients during the course of COVID-19.Integrative analyses of these omics data revealed several potential therapeutic targets,such as ANXA1 and CLEC3B.Molecular changes in plasma indicated dysregulation of macrophage and suppression of T cell functions in severe patients compared to those in non-severe patients.Further,we chose 25 important molecular signatures as potential biomarkers for the prediction of disease severity.The prediction power was validated using corresponding urine samples and plasma samples from new COVID-19 patient cohort,with AUC reached to 0.904 and 0.988,respectively.In conclusion,our omics data proposed not only potential therapeutic targets,but also biomarkers for understanding the pathogenesis of severe COVID-19. | Yuming Li Guixue Hou Haibo Zhou Yanqun Wang Hein Min Tun Airu Zhu Jingxian Zhao Fei Xiao Shanwen Lin Dongdong Liu Dunrong Zhou Lang Mai Lu Zhang Zhaoyong Zhang Lijun Kuang Jiao Guan Qiushi Chen Liyan Wen Yanjun Zhang Jianfen Zhuo Fang Li Zhen Zhuang Zhao Chen Ling Luo Donglan Liu Chunke Chen Mian Gan Nanshan Zhong Jincun Zhao Yan Ren Yonghao Xu | 2021 | Signal Transduction and Targeted Therapy2021，6，5： | 1 |
| 13 | Simulation of TV self-guided weapon显示文摘 | Zhang Yong fang Zhang An Lu Yanjun | 2012 | Transaction of Nanjing university of aeronautics and astronautics2012，24，1： | 1 |
| 14 | Profibus automation technology and its application in DP slave development显示文摘 | Xu Jun Fang YanJun | 2004 | Proceedings of the 2004 International Conference on Infomlation Acquisition2004，2004，： | 1 |
| 15 | The hydrolytic stability of some cyclourea compounds显示文摘 | Hu Rongzu Liang Yanjun Fang Yingao Wang Jinsheng Xie Yi | 1996 | Journal of Thermal Analysis1996，，5： | 1 |
| 16 | Characterization and quality assessment of binding properties of malachite green molecularly imprinted polymers prepared by precipitation polymerization in acetonitrile显示文摘 | Shoulei Yan Zhixian Gao Yanjun Fang | 2007 | Dyes and Pigments2007，74，3： | 1 |
| 17 | Bi-channel near-and far-field optical vortex generator based on a single plasmonic metasurface显示文摘With the recent development of the metasurface,generating an optical vortex in optical far or near fields is realized in various ways.However,to generate vortices in both the near and far fields simultaneously is still a challenge,although it has great potential in the future compact and versatile photonic system.Here,a bi-channel optical vortex generator in both the near and far fields is proposed and demonstrated within a single metasurface,where the surface plasmon vortex and the far-field optical vortex can be simultancously generated under circularly polarized light.The ability of generating vortices with arbitrary topological charges is experimentally demon-strated,which agrces well with simulations.This approach provides great freedom to integrate different vortex generators in a single device and ofers new opprtunities for integrated optical communications,trapping,and other related fields. | QIAO JIANG YANJUN BAO JING LI LIFENG TIAN ToNG CUI LIN SUN BOWEN DU BOWEN LI BENFENG BAI JIA WANG HONGBO SUN Bo SHEN HAN ZHANG FENG LIN XING ZHU ZHEYU FANG | 2020 | Photonics Research2020，8，6： | 1 |
| 18 | Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome显示文摘 | Yu Chen Weifeng Liang Shigui Yang Nanping Wu Hainv Gao Jifang Sheng Hangping Yao Jianer Wo Qiang Fang Dawei Cui Yongcheng Li Xing Yao Yuntao Zhang Haibo Wu Shufa Zheng Hongyan Diao Shichang Xia Yanjun Zhang Kwok-Hung Chan Hoi-Wah Tsoi Jade Lee-Lee Teng We | 2013 | The Lancet2013，，9881： | 1 |
| 19 | An on - line determination of chlorine dioxide using chlorophenol red by gas diffusion low -injection analysis 显示文摘 | Hui Chen Yanjun Fang and Kun Zhu | 1999 | Laboratory Robotic Automation1999，11，3： | 1 |
| 20 | Adsorbed silica in stalagmite carbonate and its relationship to past rainfall 显示文摘 | Hu Chaoyong Huang Junhua Fang Nianqiao Xie Shucheng Henderson G M Cai Yanjun | 2005 | Geochim Cosmochim Acta2005，69，9： | 1 |
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