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| 1 | Preservation of platelet function in patients with cirrhosis and thrombocytopenia undergoing esophageal variceal ligation显示文摘Background:Thrombocytopenia is a possible risk factor for bleeding after band ligation of esophageal varices.However,elevated von Willebrand factor(VWF)in cirrhosis improves platelet function and could decrease this risk.Our objective was to assess platelet function in patients with cirrhosis undergoing esophageal variceal ligation(EVL).Methods:The assessment consisted of platelet count,antigen and activity of VWF and VWF-cleaving protease ADAMTS-13 activity,and a platelet adhesion and aggregation test simulating vascular flow in vivo(Impact-RR)prior to EVL.Results:Totally 111 patients were divided into three groups according to platelet count:(1)<50×109/L(n=38,34.2%);(2)50×109/L to 100×109/L(n=47,42.3%);and(3)>100×109/L(n=26,23.4%).No statistically significant difference was found in the aggregate size of platelets[group 1:41.0(31.8–67.3)μm 2;group 2:47.0(33.8–71.3)μm 2;and group 3:47.0(34.0–66.0)μm 2;P=0.60]and no significant correlation was found between aggregate size and platelet count(Spearman r=0.07;P=0.47).Surface coverage was 4.1%(2.8%–6.7%),8.5%(4.0%–10.0%),and 9.0%(7.1%–12.0%)(P<0.001)in groups 1,2 and 3,respectively and correlated with platelet count(Spearman r=0.39;P<0.0001).There was no significant difference between groups in VWF or ADAMTS-13.Post-EVL bleeding occurred in six(5.4%)patients(n=2 in group 1,n=1 in group 2,and n=3 in group 3;P=0.32).Patients with bleeding had higher MELD scores[15.0(11.3–20.3)versus 12.0(10.0–15.0);P=0.025],but no difference was demonstrated for platelet function parameters.Conclusion:Platelet function is preserved even in the presence of thrombocytopenia,including in the patients with post-EVL bleeding. | Evandro de Oliveira Souza Elbio Antonio D’Amico Tania Rubia Flores da Rocha Caroline Marcondes Ferreira Juliana Medeiros Batista Luiz Augusto CarneiroD’Albuquerque Flair Jose Carrilho Alberto Queiroz Farias | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，6： | 3 |
| 2 | Targeting the PI3K/ AKT/mTOR and Raf/MEK/ERK pathways in the treatment of breast cancer 显示文摘 | Saini KS Sherene L Evandro DA | 2013 | Cancer Treat Rev2013，39，： | 1 |
| 3 | Variants of Human Papillomavirus Types 53, 58 and 66 Identified in Central Brazil显示文摘 | Daniela Marreco Cerqueira Geni Noceti de Lima Camara Márcio Rojas da Cruz Evandro Oliveira Silva Marcelo de Macedo Brígido Luciano Gon?alves de Souza Carvalho Cláudia Renata Fernandes Martins | 2003 | Virus Genes2003，，1： | 1 |
| 4 | Calibration and validation of FAO-AquaCrop model to estimate the total biomass and yacon root yield显示文摘Due to the current water scarcity in the world,it is extremely important to improve the use of this natural and exhaustible resource in agriculture,by contributing to increase agricultural production and sustainability.Several models of crop growth simulation were developed to predict the edaphoclimatic effects on crop yield.These models are calibrated and validated for a given region using the data generated from field experiments.Therefore,the objective of this study was to calibrate and validate the FAO AquaCrop model for yacon(Smallanthus sonchifolius)crop in a tropical climate.The experiment was conducted in an experimental area located in the municipality of Ibatiba,state of Espírito Santo(Brazil)during the years of 2013 and 2014.The calibration was done using the Autumn planting and validation with the Winter and Spring plantings.For the statistical analysis,the coefficient of determination,Willmott concordance index,bias for the systematic error,root mean square error and the mean absolute error to test the model performance were used.In general,the FAO AquaCrop model predicted the root yield,total biomass and harvest index with acceptable accuracy,and with deviations of less than 6%for total and root biomass.Late planting of yacon showed a reduction in yield as well as total biomass. | Ramon Amaro de Sales Alexandre Cândido Xavier Evandro Chaves de Oliveira Fábio Luiz de Oliveira Diego Mathias Natal da Silva Sávio da Silva Berilli | 2020 | International Journal of Agricultural and Biological Engineering2020，13，3： | 1 |
| 5 | Evaluation of antiulcer activity of chromanone fraction from Calophyllum brasiliesnse Camb显示文摘 | Larissa Maria Scalon Lemos Thaís Bezerra Martins Guilherme Henrique Tanajura Vanessa Fátima Gazoni Josiane Bonaldo Claudia Léia Strada Marcos Gabriel da Silva Evandro Luiz Dall’Oglio Paulo Teixeira de Sousa Júnior Domingos Tabajara de Oliveira Martins | 2012 | Journal of Ethnopharmacology2012，，1： | 1 |
| 6 | Chemical Constituents and Evaluation of Antimicrobial and Cytotoxic Activities of Kielmeyera coriacea Mart. & Zucc. Essential Oils显示文摘 | Carla de M. Martins Evandro A. do Nascimento Sérgio A. L. de Morais Alberto de Oliveira Roberto Chang Luís C. S. Cunha Mário M. Martins Carlos Henrique G. Martins Thaís da S. Moraes Paulla V. Rodrigues Cláudio V. da Silva Francisco J. T. de Aquino Filippo | 2015 | Evidence-Based Complementary and Alternative Medicine2015，，： | 1 |
| 7 | Prevalence of hysteroscopic findings and histologic diagnoses in patients with abnormal uterine bleeding显示文摘 | Ricardo Bassil Lasmar Rogério Dias Paulo Roberto Mussel Barrozo Marco Aurélio Pinho Oliveira Evandro da Silva Freire Coutinho Daniela Baltar da Rosa | 2008 | Fertility and Sterility2008，，6： | 1 |
| 8 | Development and Improvement of the Regulation Sieve Svstem Harvester显示文摘 | Evandro Bertoldi Gil Eduardo Guimaraes Luiz Carlos da Silva Duarte Patricia Carolina Pedrali ClaudioFernando Rios Nara Liege Barbieri Everton Bertoldi | 2014 | Journal of Mechanics Engineering and Automation2014，4，8： | 0 |
| 9 | Participatory Governance and Decision-Making: Oil and Gas in Santos (Brazil)显示文摘 | Edison da Silva Montelro Eduardo Mario Dias Evandro Prestes Guerreiro Maria Lidia Rebello P. Dias | 2013 | Journal of Chemistry and Chemical Engineering2013，7，7： | 0 |
| 10 | Eurytrematosis: An emerging and neglected disease in South Brazil显示文摘The trematodes of the genus Eurytrema are low pathogenic pancreatic parasites, but can be related to a decrease in cattle productive performance and eventually death. Parasitized animals develop chronic interstitial pancreatitis and may show a productive performance drop and emaciation. Human infection by Eurytrema sp. has already been reported in other countries as an incidental finding during autopsy or routine tests, but the parasite has not been found in humans in Brazil. However, it is possible that a large number of people could be infected, since parasitological tests have low sensitivity and the parasite is neglected as a pathogen for humans and even animals. Attempts to control and treat Eurytrematosis have generally presented low effectiveness. With the aim to control the disease and provide more information regarding its pathogenicity, our research group is developing a number of studies about Eurytrema spp. We hope to determine the damage in productivity, as well as, establish an efficient protocol for treatment and control of Eurytrematosis based on immunoprophylaxis and antiparasitical drug therapy. | Claiton Ismael Schwertz Neuber Jose Lucca Aleksandro Schafer da Silva Piotr Baska Gustavo Bonetto Mateus Eloir Gabriel Fábio Centofanti Ricardo Evandro Mendes | 2015 | World Journal of Experimental Medicine2015，5，3： | 0 |
| 11 | Ingredients from integral valorization of Isabel grape to formulate goat yogurt with stimulatory effects on probiotics and beneficial impacts on human colonic microbiota in vitro显示文摘Isabel grape(IG)products have high contents of phenolic compounds and fiber recognized for their positive impacts on microorganisms associated with health benefits to host.This study evaluated the effects of goat yogurts formulated with ingredients from IG integral valorization on the growth and metabolism of different probiotic strains,as well as on the population of selected bacterial groups and metabolic activity of human colonic microbiota in vitro.Goat yogurts with IG ingredients(IGI)stimulated the growth of tested Lactobacillus and Bifidobacterium probiotic strains during a 48-h cultivation,as well as decreased the pH values and enhanced the organic acid production.Goat yogurts with IGI increased the population of Lactobacillus spp.and Bifidobacterium spp.during a 24-h in vitro colonic fermentation.A stable Firmicutes:Bacteroidetes ratio close to 1 was found in media with goat yogurt formulations during the colonic fermentation,being similar to the effect caused by fructooligosaccharides.Goat yogurt formulations with IGI caused increased production of short-chain fatty acids and sugar consumption during colonic fermentation.Goat yogurts with IGI should be a valuable strategy for development of novel added-value foods with beneficial effects on gut microbiota and human health. | Francyeli Araújo Silva Rita de Cássia Ramos do Egypto Queiroga Evandro Leite de Souza Glenise Bierhalz Voss Maria Manuela Estevez Pintado Margarida Angélica da Silva Vasconcelos | 2023 | Food Science and Human Wellness2023，12，4： | 0 |
| 12 | Prognosis of forest production using machine learning techniques显示文摘Forest production and growth are obtained from statistical models that allow the generation of information at the tree or forest stand level.Although the use of regression models is common in forest measurement,there is a constant search for estimation procedures that provide greater accuracy.Recently,machine learning techniques have been used with satisfactory performance in measuring forests.However,methods such as Adaptive NeuroFuzzy Inference System(ANFIS)and Random Forest are relatively poorly studied for predicting the volume of wood in eucalyptus plantations in Brazil.Therefore,it is essential to check whether these techniques can provide gains in terms of accuracy.Thus,this study aimed to evaluate the use of Random Forest and ANFIS techniques in the prognosis of forest production.The data used come from continuous forest inventories carried out in stands of eucalyptus clones.The data were divided into 70%for training and 30%for validation.The algorithms used to generate rules in ANFIS were Subtractive Clustering and Fuzzy-C-Means.Besides,training was done with the hybrid algorithm(descending gradient and least squares)with the number of seasons ranging from 1 to 20.Several RFs were trained,varying the number of trees from 50 to 850 and the number of observations by five leaves to 35.Artificial neural networks and decision trees were also trained to compare the feasibility of the techniques.The evaluation of the estimates generated by the techniques for training and validation was calculated based on the following statistics:correlation coefficient(r),relative Bias(RB),and the relative root mean square error(RRMSE)in percentage.In general,the techniques studied in this work showed excellent performance for the training and validation data set with RRMSE values<6%,RB<0.5%,and r>0.98.The RF presented inferior statistics about the ANFIS for the prognosis of forest production.The Subtractive Clustering(SC)and Fuzzy-C-Means(FCM)algorithms provide accurate baseline and volume projection estimates;both techniques are good alternatives for selecting variables used in modeling forest production. | Jeferson Pereira Martins Silva Mayra Luiza Marques da Silva Adriano Ribeiro de Mendonca Gilson Fernandes da Silva Antoˆnio Almeida de Barros Junior Evandro Ferreira da Silva Marcelo Otone Aguiar Jeangelis Silva Santos Nı´vea Maria Mafra Rodrigues | 2023 | Information Processing in Agriculture2023，10，1： | 0 |
| 13 | Prognostic factors for progression of liver structural lesions in chronic hepatitis C patients显示文摘AIM: To evaluate the epidemiological, clinical, laboratory and histological variables capable of predicting the progression of hepatic structural disturbances in chronic hepatitis C patients during the time interval between two liver biopsies. METHODS: Clinical charts of 112 chronic hepatitis C patients were retrospectively analyzed, whereas liver biopsies were revised. Immunohistochemical detection of interferon receptor was based on the Envision-Peroxidase System. RESULTS: In the multivariate analysis, the variables in the age at first biopsy, ALT levels, presence of lymphoid aggregates and siderosis were the determinants of the best model for predicting the severity of the disease. The direct progression rate of hepatic structural lesions was significantly higher in untreated patients, intermediate in treated non-responders and lower in treated responders to antiviral therapy (non-treated vs responders, 0.22 ± 0.50 vs -0.15 ± 0.46, P = 0.0053). Immuno-expression of interferon receptor is not a relevant factor. CONCLUSION: The best predictors of the progression of fibrosis are age at the first liver biopsy, extent of ALT elevation, inflammation at liver histology and hepatic siderosis. Antiviral treatment is effective in preventing the progression of liver structural lesions in chronic hepatitis C patients. | Liliana SC Mendes Marcelo E Nita Suzane K Ono-Nita Evandro S Mello Luiz Caetano da Silva Venancio AF Alves Flair J Carrilho | 2008 | World Journal of Gastroenterology2008，14，16： | 0 |
| 14 | 决定巴西Espinhaco生物圈保护区森林-草地变化的环境因素显示文摘关于热带雨林(对火敏感)和开放地层(耐火)之间边界所涉及过程的认识对于保护生物多样性和生态系统服务至关重要,尤其是在气候变化和人为压力增加的情况下。本文调查了位于巴西东南部的Espinhaco生物圈保护区内的森林岛屿和湿润草原同时出现的主要环境因素。我们使用Costa(2018)布置的永久样地来收集森林岛屿的土壤变量(水分和化学性质)。对于湿润草原的采样,我们从岛屿边缘沿不同方向设置了4条30m的线。随后,我们在每条线上划了3个点,每个点相距10m,每个区域共12个点。我们还调查了处理火烧前后的植被覆盖情况,并对环境变量进行均值检验和主成分分析。研究结果显示,森林岛屿土壤中钾、盐基总量、阳离子交换容量和有机质的值均高于湿润草地。因此,两种植被类型之间的边界定义似乎主要与土壤肥力和水分梯度有关。在对这些地区进行火烧处理后,在岛屿边缘附近没有发现树木个体的再生。因此,这些研究结果表明,由于明确的土壤气候条件,森林岛屿无法扩张。因此,这些环境应该成为设计公共保护政策的目标焦点,因为它们增加了山地岩石草原植被景观的复杂性。 | Thais Ribeiro Costa Cristiane Coelho de Moura Leovandes Soares da Silva Anne Priscila Dias Gonzaga AndréRodrigo Rech Evandro Luiz Mendonga Machado | 2023 | Journal of Plant Ecology2023，16，5： | 0 |
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