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90篇 您的检索式:作者名="Strada"
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1Dual Gabriel theorem with applications显示文摘We introduce the quiver of a bicomodule over a cosemisimple coalgebra. Applying this to the coradical C0 of an arbitrary coalgebra C, we give an alternative definition of the Gabriel quiver of C, and then show that it coincides with the known Ext quiver of C and the link quiver of C. The dual Gabriel theorem for a coalgebra with a separable coradical is obtained, which generalizes the corresponding result for a pointed coalgebra. We also give a new description of C1 = C0 ∧X C0 of any coalgebra C, which can be regarded as a generalization of the first part of the well-known Taft-Wilson Theorem for pointed coalgebras. As applications, we give a characterization of locally finite coalgebras via their Gabriel quivers, and a property of the Gabriel quiver of a quasi-coFrobenius coalgebra.CHEN Xiaowu, HUANG Hualin & ZHANG Pu Department of Mathematics, University of Science and Technology of China, Hefei 230026, China USTC Shanghai Institute for Advanced Studies, Shanghai 201315, China Mathematical Section, the Abdus Salam ICTP, Strada Costiera 11, Trieste 34014, Italy Department of Mathematics, Shanghai Jiao Tong University, Shanghai 200030, China 2006Science China Mathematics2006,49,1:6
2Role of the advanced glycation end products receptor in Crohn's disease inflammation显示文摘AIM:To investigate the level of mucosal expression and the involvement of the receptor for the advanced glycation end products(RAGE)in delayed apoptosis and tumor necrosis factor(TNF)-αproduction in Crohn’s disease(CD).METHODS:Surgical and endoscopic specimens from both inflamed and non-inflamed areas of the ileum and/or colon were collected from 20 and 14 adult CD patients,respectively,and used for the assessment of RAGE expression by means of immunohistochemistry and western blotting analysis.Normal tissues from 21 control subjects were used for comparison.The same polyclonal anti-human RAGE antibody(R and D System)was used in all experimental conditions.RAGE staining was quantized by a score including both the amount of positive cells and intensity of immunoreactivity;cellular pattern was also described.The effects of RAGE blocking on apoptotic rate and TNF-αproduction were investigated on immune cells freshly isolated from CD mucosa and incubated both with and without the muramyl dipeptide used as antigenic stimulus.Statistical analysis was performed via the test for trend,with regression models to account for intra-patient correlations.A 2-sided P<0.05 was considered significant.RESULTS:In inflamed areas,RAGE expression in both the epithelial and lamina propria compartments was higher than control tissues(P=0.001 and 0.021,respectively),and a cluster of positive cells were usually found in proximity of ulcerative lesions.Similar results were obtained in the lamina propria compartment of non-inflamed areas(P=0.025).The pattern of staining was membranous and granular cytosolic at the epithelial level,while in the lamina propria it was diffuse cytosolic.When evaluating the amount of protein expression by immunoblotting,a significant increase of both surface area and band intensity(P<0.0001 for both)was observed in CD inflamed areas compared to control tissue,while in non-inflamed areas a significant increase was found only for band intensity(P<0.005).Moreover,a significantly lower expression in noninflamed areas in comparison with inflamed areas was found for both surface area and band intensity(P<0.0006 for both).Finally,RAGE blocking largely affects both the apoptotic rate of mucosal cells(towards an increase in both non-inflamed and inflamed areas of P<0.001 and<0.0001,respectively)and TNF-αsecretion(towards a decrease in both non-inflamed and inflamed areas of P<0.05 and<0.01,respectively),mainly in the presence of antigenic stimulation.CONCLUSION:RAGE is up-regulated in CD,especially in inflamed areas,and it appears to play a role in the mechanisms involved in chronic inflammation.Rachele Ciccocioppo Alessandro Vanoli Catherine Klersy Venerina Imbesi Vincenzo Boccaccio Rachele Manca Elena Betti Giuseppina Cristina Cangemi Elena Strada Roberta Besio Antonio Rossi Colomba Falcone Sandro Ardizzone Paolo Fociani Piergiorgio Danelli Gino Roberto Corazza 2013World Journal of Gastroenterology2013,19,45:2
3Magnetic resonance imaging in progress supanuclear palsy and other parkinsonian disorders 显示文摘Savoiardo M GirottiF Strada L 1994J Neuuroltransm Suppl1994,42,:1
4Neurotoxicity of Platinum Compounds: Comparison of the Effects of Cisplatin and Oxaliplatin on the Human Neuroblastoma Cell Line SH-SY5Y显示文摘Elisabetta Donzelli Maria Carfì Mariarosaria Miloso Alberto Strada Stefania Galbiati Martine Bayssas Genevieve Griffon-Etienne Guido Cavaletti Maria Grazia Petruccioli Giovanni Tredici 2004Journal of Neuro - Oncology (-)2004,,1:1
5Injury severity score versus new injury severity score for penetrating injuries 显示文摘Husun H Strada G 2002Pre Dis Med2002,17,1:1
6Olivopontocerebellar atro phy: MR diagnosis and relationship to muhiple system atrophy 显示文摘Savoiardo M Strada L Girotti F 1990Radiology1990,174,3:1
7Cyclic nucleotide phosphodiesterases and vascular smooth muscle显示文摘Polson JB Strada SJ 1996Annu Rev Pharmacol Toxicol1996,36,:1
8First-linechemo therapy with vinorelbine, gemcitabine, and carboplatin in the treatmentof brain metastas esfrom non-small·-celllung can cer: a phase IIstudy显示文摘Bernardo G Cuzzoni Q Strada M R 2002CancerInvest2002,20,3:1
9Olivopontocerebellar atrophy: MR diagnosis and relationship to multisystem atrophy 显示文摘Savoiardo M Strada L Girotti F 1990Radiology1990,174,31:1
10First-line chemotherapy with vinorelbine, gemcitabine, and carhoplatin in the treatment of brain matastases from non-small-cell lung cancer: a phase Ⅱ study 显示文摘Bernardo G Cuzzoni Q Strada MR 2002Cancer Invest2002,20,3:1
11First-line chemotherapy with vinorelbine, gemcitabine and carboplatin in the treatment of brain metastases from non-small-cell lung cancer: a phase Ⅱ study 显示文摘Bemardo G Cuzzoni Q Strada MR 2002Cancer Invest2002,20,3:1
12Platelet lysate fa- vours in vitro expansion of human bone marrow stromal ceils for bone and cartilage engineering显示文摘Zaky SH Ottonello A Strada P 2008J Tissue Eng Regen Meal2008,2,8:1
13Leydig cell tumour of the testis : presenta-tion ,therapy,long - term follow - up and the role of organ - spar-ing surgery in a single - institution experience 显示文摘Strada E Colombo R 2009BJU Int2009,103,2:1
14Leydig cell tumour of the testis : presentation, therapy, long- term follow- up and the role of organ-sparing surgery in a single-institution ex- perience 显示文摘SURADI N STRADA E COLOMBO R 2009BJU Int2009,103,2:1
15Leydig cell tumour of the testis:presentation,therapy,long-term follow-up and the role of organ-sparing surgery in a single-institution experience显示文摘Suardi N Strada E Colombo R 2009BJU Int2009,103,2:1
16Acute pain response in infants: A multidimensional description 显示文摘Johnston CC Strada ME 1986Pain1986,24,:1
17Intravenous or o- ral vinorelbine plus capecitabine as first-line treatment in HER2- metastatic breast cancer joint analysis of 2 consecutive prospective phase Ⅱ trials 显示文摘Strada MR Palumbo R Bernardo A 2012Clin Breast Cancer2012,12,1:1
18Tree and fruit characters of several genetic semi-dwarf peach selection 显示文摘Fideghelli C Quarta R Delia Strada G 1983Ann Ist Sper Fruit1983,47,:1
19Intravenous or oralvinorelbine plus capecitabine as first-line treatment in HER2-metastatic breast cancer:jointanalysis of 2 consecutive prospectivephase Ⅱ trials显示文摘Strada MR Palumbo R Bernardo A 2012Clin Breast Cancer2012,12,1:1
20Olivopontocerebellar atrophy:MR diagnosis and relationship to multisystem atrophy显示文摘Savoiardo M Strada L Girotti F 1990Radiology1990,174,:1
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