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| 1 | Total knee arthroplasty and fractures of the tibial plateau显示文摘Tibial plateau fractures are common injuries that occur in a bimodal age distribution. While there are various treatment options for displaced tibial plateau fractures, the standard of care is open reduction and internal fixation(ORIF). In physiologically young patients with higher demand and better bone quality, ORIF is the preferred method of treating these fractures. However, future total knee arthroplasty(TKA) is a consideration in these patients as post-traumatic osteoarthritis is a common long-term complication of tibial plateau fractures. In older, lower demand patients, ORIF is potentially less favorable for a variety of reasons, namely fixation failure and the need for delayed weight bearing. In some of these patients, TKA can be considered as primary mode of treatment. This paper will review the literature surrounding TKA as both primary treatment and as a salvage measure in patients with fractures of the tibial plateau. The outcomes, complications, techniques and surgical challenges are also discussed. | Kenneth A Softness Ryan S Murray Brian G Evans | 2017 | World Journal of Orthopedics2017，8，2： | 15 |
| 2 | Genetics of coronary artery disease and myocardial infarction显示文摘Atherosclerotic coronary artery disease(CAD) comprises a broad spectrum of clinical entities that include asymptomatic subclinical atherosclerosis and its clinical complications, such as angina pectoris, myocardial infarction(MI) and sudden cardiac death. CAD continues to be the leading cause of death in industrialized society. The long-recognized familial clustering of CAD suggests that genetics plays a central role in its development, with the heritability of CAD and MI estimated at approximately 50% to 60%. Understanding the genetic architecture of CAD and MI has proven to be difficult and costly due to the heterogeneity of clinical CAD and the underlying multi-decade complex pathophysiological processes that involve both genetic and environmental interactions. This review describes the clinical heterogeneity of CAD and MI to clarify the disease spectrum in genetic studies, provides a brief overview of the historical understanding and estimation of the heritability of CAD and MI, recounts major gene discoveries of potential causal mutations in familial CAD and MI, summarizes CAD and MIassociated genetic variants identified using candidate gene approaches and genome-wide association studies(GWAS), and summarizes the current status of the construction and validations of genetic risk scores for lifetime risk prediction and guidance for preventive strategies. Potential protective genetic factors against the development of CAD and MI are also discussed. Finally, GWAS have identified multiple genetic factors associated with an increased risk of in-stent restenosis following stent placement for obstructive CAD. This review will also address genetic factors associated with in-stent restenosis, which may ultimately guide clinical decision-making regarding revascularization strategies for patients with CAD and MI. | Xuming Dai Szymon Wiernek James P Evans Marschall S Runge | 2016 | World Journal of Cardiology2016，8，1： | 15 |
| 3 | The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming显示文摘新陈代谢对房间功能的每个方面重要,然而,导致的 pluripotent 干细胞(iPSCs ) 的 metabolome 仍然保持大部分未经勘探。这里,我们报导,用一条 untargeted metabolomics 途径,那人的 iPSCs 份额有从他们的父母房间是不同的胚胎的干细胞(转换字符) 的 pluripotent metabolomic 签名,并且那被变化在涉及细胞的呼吸的代谢物描绘。细胞的 bioenergetics 的检查与我们的 metabolomic 分析支持了,并且证明体的房间在 pluripotency 从一个氧化状态变换成一个 glycolytic 状态。有趣地,各种各样的体的房间的 bioenergetics 与他们的 reprogramming 效率相关。我们进一步识别了在 iPSCs 和转换字符之间不同的代谢物,它揭示了在调整体的房间 reprogramming 起一个关键作用的新奇新陈代谢的小径。我们的调查结果是第一全球性分析 iPSCs 的 metabolome,并且提供机械学的卓见进涉及导致 pluripotency,并且在评估 iPSC 和转换字符等价的规定的新层。 | Athanasia D Panopoulos Oscar Yanes Sergio Ruiz Yasuyuki S Kida Dinh Diep Ralf Tautenhahn Aida Herrerias Erika M Batchelder Nongluk Plongthongkum Margaret Lutz W Travis Berggren Kun Zhang Ronald M Evans Gary Siuzdak Juan Carlos Izpisua Belmonte] | 2012 | Cell Research2012，22，1： | 12 |
| 4 | Acute liver failure due to natural killer-like T-cell leukemia/ lymphoma: A case report and review of the Literature显示文摘尖锐的肝失败(ALF ) 是为肝移植要求立即的评估的一种医药紧急情况。我们描述与腹水,黄疸,和脑病介绍了并且被发现由于象 T 房间白血病 / 淋巴瘤一样的生来的杀手(NK ) 有 ALF 的一个病人的一个不平常的盒子。关键免疫显型是 CD2+ , CD3+ , CD7+ , CD56+ 。这诊断,在外部血和腹水基于调查结果,与肝活体检视被证实,并且是到肝移植的禁止徵候。hematologic 恶意是暴发性的肝的失败的一个不平常的原因的文学表演的评论,和那个象 NK 一样 T 房间白血病 / 淋巴瘤是一最近相对表示特性地认出了是的实体 CD3+ 和 CD56+ 。这个盒子证明那肝活体检视在与淋巴瘤 / 白血病能引起尖锐的肝失败的象 NK 一样 T 房间诊断肝的尖锐的肝失败,和那渗入的不平常的原因是必要的。 | Evan S Dellon Shannon R Morris Wozhan Tang Cherie H Dunphy Mark W Russo | 2006 | World Journal of Gastroenterology2006，12，25： | 5 |
| 5 | Guidelines and Good Clinical Practice Recommendations for Contrast Enhanced Ultrasound (CEUS) - Update 2008显示文摘 | M Claudon D Cosgrove T Albrecht L Bolondi M Bosio F Calliada J.-M Correas K Darge C Dietrich M D’Onofrio D Evans C Filice L Greiner K J?ger N Jong E Leen R Lencioni D Lindsell A Martegani S Meairs C Nols?e F Piscaglia P Ricci G Seidel B Skjoldbye L Solbia | 2008 | Ultraschall in Med2008，，01： | 4 |
| 6 | Guidelines and Good Clinical Practice Recommendations for Contrast Enhanced Ultrasound (CEUS) - Update 2008显示文摘 | M Claudon D Cosgrove T Albrecht L Bolondi M Bosio F Calliada J.-M Correas K Darge C Dietrich M D'Onofrio D Evans C Filice L Greiner K J?ger N Jong E Leen R Lencioni D Lindsell A Martegani S Meairs C Nols?e F Piscaglia P Ricci G Seidel B Skjoldbye L Solbia | 2008 | Ultraschall in Med2008，，01： | 3 |
| 7 | Analysis of somatostatin receptor subtype mRNA expression in human breast cancer显示文摘 | Evans AA Crook T Laws S | 1997 | BrJ Cancer1997，75，： | 2 |
| 8 | High early morta-lity rate from acute pancreatitis显示文摘 | Mckay CJ Evans S Sindair M | 2000 | Br J Surg2000，87，3： | 2 |
| 9 | Posterior interosseous nerve localization within the proximal forearm-a patient normalized parameter显示文摘AIM To provide a 'patient-normalized' parameter in the proximal forearm. METHODS Sixty-three cadaveric upper extremities from thirty-five cadavers were studied. A muscle splitting approach was utilized to locate the posterior interosseous nerve(PIN) at the point where it emerges from beneath the supinator. The supinator was carefully incised to expose the midpoint length of the nerve as it passes into the forearm while preserving the associated fascial connections, thereby preserving the relationship of the nerve with the muscle. We measured the transepicondylar distance(TED), PIN distance in the forearm's neutral rotation position, pronation position, supination position, and the nerve width. Two individuals performed measurements using a digital caliper with inter-observer and intraobserver blinding. The results were analyzed with the Wilcoxon-Mann-Whitney test for paired samples. RESULTS In pronation, the PIN was within two confidence intervals of 1.0 TED in 95% of cases(range 0.7-1.3 TED); in neutral, within two confidence intervals of 0.84 TED in 95% of cases(range 0.5-1.1 TED); in supination,within two confidence intervals of 0.72 TED in 95% of cases(range 0.5-0.9 TED). The mean PIN distance from the lateral epicondyle was 100% of TED in a pronated forearm, 84% in neutral, and 72% in supination. Predictive accuracy was highest in supination; in all cases the majority of specimens(90.47%-95.23%) are within 2 cm of the forearm position-specific percentage of TED. When comparing right to left sides for TEDs with the signed Wilcoxon-Mann-Whitney test for paired samples as well as a significance test(with normal distribution), the P-value was 0.0357(significance-0.05) indicating a significant difference between the two sides.CONCLUSION This 'patient normalized' parameter localizes the PIN crossing a line drawn between the lateral epicondyle and the radial styloid. Accurate PIN localization will aid in diagnosis, injections, and surgical approaches. | Srinath Kamineni Crystal R Norgren Evan M Davidson Ellora P Kamineni Andrew S Deane | 2017 | World Journal of Orthopedics2017，8，4： | 2 |
| 10 | proton binding and cadminum complexation constants for a soil humic acid using a Quase - partucle nidek显示文摘 | Bolton K A Sjoberg S and Evans L J | 1996 | Soil sci sik an hm1996，60，： | 2 |
| 11 | Adverse events of upper GI endoscopy显示文摘 | Tamir Ben-Menachem G. Anton Decker Dayna S. Early Jerry Evans Robert D. Fanelli Deborah A. Fisher Laurel Fisher Norio Fukami Joo Ha Hwang Steven O. Ikenberry Rajeev Jain Terry L. Jue Khalid M. Khan Mary L. Krinsky Phyllis M. Malpas John T. Maple Ravi N. S | 2012 | Gastrointestinal Endoscopy2012，，4： | 2 |
| 12 | Yttrium-90 microsphere selective internal radiation therapy for liver metastases following systemic chemotherapy and surgical resection for metastatic adrenocortical carcinoma显示文摘Adrenocortical carcinoma(ACC)is a rare malignancy with generally poor outcomes and limited treatment options.While surgical resection can be curative for early local disease,most patients present with advanced ACC owing to nonspecific symptoms.For those patients,treatment options include systemic chemotherapy and locoregional therapies including radiofrequency ablation and transarterial chemoembolization.We present the first reported case of utilizing yttrium-90 microsphere selective internal radiation therapy(SIRT)in combination with first line EDP-M(Etoposide,Doxorubicin,Cisplatin,Mitotane)chemotherapy and debulking surgical primary tumor resection for treatment of metastatic ACC.Stable complete radiologic response has been maintained after twelve months with resolution of clinical symptoms.These findings prompt the need for further consideration and studies to elucidate the role of SIRT in combination with systemic and surgical treatment for metastatic ACC. | Mina S Makary Lawrence S Krishner Evan J Wuthrick Mark P Bloomston Joshua D Dowell | 2018 | World Journal of Clinical Oncology2018，9，1： | 2 |
| 13 | Apoptosis of human vascular smooth muscle cells derived from normal vessels couonary atheresclerotic plaques 显示文摘 | Bennet M Evan G Schwartz S | 1995 | Clin invest1995，95，5： | 1 |
| 14 | Gene transfer approaches to the healing of bone and cartilage显示文摘 | Lieberman J R Ghivizzani S C Evans C H | 2002 | Mol Ther2002，6，： | 1 |
| 15 | Glacier depth sounding from the air显示文摘 | Evans S Robin G Q | 1966 | Nature1966，210，： | 1 |
| 16 | Performance of dynamic programming techniques for track-before-detect显示文摘 | Tonissen S M Evans R J | 1996 | IEEE Transactions on Aerospace and Electronic Systems1996，32，4： | 1 |
| 17 | Correlations between the mammographic features of ductal carcinoma in situ(DCIS) and c-erbB-2 oncogene expression显示文摘 | Pinder S E Ellis I O | 1994 | Clin Radiol1994，49，8： | 1 |
| 18 | Image quality assessment based on a degradation 显示文摘 | Kite T D Gersler W S Evans B L | 2000 | IEEE Transactions on Image Processing2000，9，4： | 1 |
| 19 | Rapid synthesis of ZrW2O8 and related phases,and structure refinement of ZrWMoO8显示文摘 | SLEIGHT A W EVANS J S O | 2000 | International Journal of Inorganic Materials2000，2，： | 1 |
| 20 | Forest litter production,chemistry,and decomposition following two years of free air CO2 enrichment显示文摘 | ADRIEN C F ANDREW S A EVAN H D | 2001 | Ecology2001，82，2： | 1 |
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