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    题名 作者 年代 出处 被引量
1从国际视野重新审视家校合作--《学校、家庭和社区合作伙伴:行动手册》中文版序显示文摘一 本书是Epstein教授研究和指导家校合作工作的代表作和集大成之作.'家校合作'是国内的提法,在国外(以及在本书中)对应的概念是'学校、家庭(和社区)合作伙伴关系'(School,Family,and Community Partnerships). 这是一本写给美国教师、家长、校长和各级教育行政领导阅读的关于家校合作的经典工具书.无疑,从书名就可以看出,这是一本指导学校如何开展家校合作活动的行动指南,是按照家校合作的行动者的实践逻辑展开的,提供了详尽的、一步一步的家校合作行动策略.书中详细描述了美国、加拿大家校合作的实践框架、组织架构、制订计划与实施,对活动组织参与者的专业培训,分幼、小、初、高各学段和学校、学区和州各个行政层次的行动和责任特点,教师必须具备的有关专业知识、能力和工作内容,如何评估和选择有效的家校合作活动等等,具有很强的、系统的实践指导性.Epstein 吴重涵 2013教育学术月刊2013,,1:31
2Evolution of systemic therapy of advanced hepatocellular carcinoma显示文摘Hepatocellular carcinoma (HCC) commonly occurs in hepatitis B endemic areas, especially in Asian countries. HCC is highly refractory to cytotoxic chemotherapy. This resistance is partly related to its tumor biology, pharmacokinetic properties, and both intrinsic and acquired drug resistance. There is no convincing evidence thus far that systemic chemotherapy improves overall survival in advanced HCC patients. Other systemic approaches, such as hormonal therapy and immunotherapy, have also disappointing results. Recently, encouraging results have been shown in using sorafenib in the treatment of advanced HCC patients. In this review, we concisely summarize the evolution of developments in the systemic therapy of advanced HCC.Thomas Yau Pierre Chan Richard Epstein Ronnie T Poon 2008World Journal of Gastroenterology2008,14,42:23
3螺旋CT多期扫描在进展期胃癌术前分期的价值(英文)显示文摘目的 :评价螺旋CT多期扫描在进展期胃癌术前分期的价值。材料和方法 :前瞻性研究一组36例胃癌病例 ,采用国际胃癌协会通用的TNM标准 ,螺旋CT与手术和病理对照 ,观察螺旋CT对进展期胃癌病变的检出率 ,分期的准确性。结果 :36例进展期胃癌 ,螺旋CT病变检出率100 % ,分期准确性83.33 %(25/30),3例(10 %)CT分期低于外科病理分期 ,2例(6.66 %)CT分期高于外科病理分期。结论 :螺旋CT多期扫描在胃癌术前分期方面有较高的准确性 ,值得临床应用。彭卫军 周康荣 秦新裕 Robert Epstein 2001中国医学计算机成像杂志2001,7,3:8
4可应用于民机空气动力设计中的数值优化方法显示文摘目前民机成功设计的一个关键要素即在设计中有效地引入计算流体力学(CFD)的模拟方法和软件,特别是具有设计能力的方法和工具。本文概要地叙述了反设计、基于CFD低可信度和高可信度模型等数值优化方法的发展和应用于民机设计的历史和现状;简单地介绍了即将举行的空气动力优化设计计算系列研讨会;重点讨论了对可应用于民机设计的基于Navier-Stokes方程解算器的OPTIMAS的数值优化方法的要求及其构造方法,并以翼身组合体整流外形和翼身融合体(BWB)外形的算例表明其有效性,说明OPTIMAS可以成为民机日常设计的方法和工具之一。Sergey PEIGIN 朱自强 Boris EPSTEIN 2014航空学报2014,35,1:8
5中国部分城市重型血友病A患者医疗及预后现状调查分析显示文摘血友病是一种遗传性出血性疾病,是由于凝血因子Ⅷ(FⅧ)或FⅨ基因突变导致人体内FⅧ或FⅨ水平降低或缺乏,从而导致出血。本病分为血友病A(FⅧ减少或缺乏)和血友病B(FⅨ减少或缺乏)。薛峰 周泽平 杨仁池 Joshua Epstein Yan Xiong 2011中华血液学杂志2011,32,7:7
6中药治疗海洛因依赖急性戒断症状的Meta分析显示文摘目的:系统评价中药治疗海洛因依赖急性戒断症状的有效性与安全性。方法:计算机检索多种中英文数据库,收集中、西药(α2-肾上腺素受体激动剂或阿片受体激动剂)对比研究海洛因脱毒的随机对照实验(RCT)。采用Jadad量表对纳入研究进行质量评价,并采用RevM an软件以固定效应和随机效应模型进行M eta分析。评价指标包括:戒断症状评分、焦虑评分及不良反应发生率。结果:共纳入21个实验(共2949位受试者)。结果显示:对于戒断症状的缓解,在疗程的d4-10(d8除外),中药组优于α2-受体激动剂组,在疗程的前3 d,两者无显著性差异。与阿片受体激动剂相比,在疗程前3 d,中药略显逊色,但在疗程d4-9,两者疗效相当。对于焦虑的缓解,中药组与阿片受体激动剂组相比无显著性差异,但与α2-受体激动剂组相比,中药在疗程后期显示出优越性。另外,在某些不良反应(疲乏、眩晕)发生率上,中药组也显著低于α2-受体激动剂组(阿片受体激动剂组数据不足,未分析)。结论:现有数据表明,中药是海洛因依赖脱毒有效而安全的治疗方法。但对于中药特定方剂的特定疗效还需要有进一步的研究。刘婷婷 时杰 David H Epstein 鲍彦平 陆林 2011中国药物依赖性杂志2011,20,4:6
7Statistical variances of diffusional properties from ab initio molecular dynamics simulations显示文摘Ab initio molecular dynamics(AIMD)simulation is widely employed in studying diffusion mechanisms and in quantifying diffusional properties of materials.However,AIMD simulations are often limited to a few hundred atoms and a short,sub-nanosecond physical timescale,which leads to models that include only a limited number of diffusion events.As a result,the diffusional properties obtained from AIMD simulations are often plagued by poor statistics.In this paper,we re-examine the process to estimate diffusivity and ionic conductivity from the AIMD simulations and establish the procedure to minimize the fitting errors.In addition,we propose methods for quantifying the statistical variance of the diffusivity and ionic conductivity from the number of diffusion events observed during the AIMD simulation.Since an adequate number of diffusion events must be sampled,AIMD simulations should be sufficiently long and can only be performed on materials with reasonably fast diffusion.We chart the ranges of materials and physical conditions that can be accessible by AIMD simulations in studying diffusional properties.Our work provides the foundation for quantifying the statistical confidence levels of diffusion results from AIMD simulations and for correctly employing this powerful technique.Xingfeng He Yizhou Zhu Alexander Epstein Yifei Mo 2018npj Computational Materials2018,,1:6
8Role of virtual reality simulation in endoscopy training显示文摘Recent advancements in virtual reality graphics and models have allowed virtual reality simulators to be incorporated into a variety of endoscopic training programmes. Use of virtual reality simulators in training programmes is thought to improve skill acquisition amongst trainees which is reflected in improved patient comfort and safety. Several studies have already been carried out to ascertain the impact that usage of virtual reality simulators may have upon trainee learning curves and how this may translate to patient comfort. This article reviews the available literature in this area of medical education which is particularly relevant to all parties involved in endoscopy training and curriculum development. Assessment of the available evidence for an optimal exposure time with virtual reality simula-tors and the long-term benefits of their use are also discussed.Louis Harpham--Lockyer Faidon--Marios Laskaratos Pasquale Berlingieri Owen Epstein 2015World Journal of Gastrointestinal Endoscopy2015,7,18:5
9Update on Cardiovascular Implantable Electronic Device Infections and Their Management: A Scientific Statement From the American Heart Association显示文摘Larry M. Baddour Andrew E. Epstein Christopher C. Erickson Bradley P. Knight Matthew E. Levison Peter B. Lockhart Frederick A. Masoudi Eric J. Okum Walter R. Wilson Lee B. Beerman Ann F. Bolger N A. Mark Estes Michael Gewitz Jane W. Newburger Eleanor B. S 2010Circulation2010,,3:4
10Critical role of OX40 signaling in the TCR-independent phase of human and murine thymic Treg generation显示文摘Regulatory T cells(Tregs)play a pivotal role in immune-tolerance,and loss of Treg function can lead to the development of autoimmunity.Natural Tregs generated in the thymus substantially contribute to the Treg pool in the periphery,where they suppress self-reactive effector T cells(Teff)responses.Recently,we showed that OX40L(TNFSF4)is able to drive selective proliferation of peripheral Tregs independent of canonical antigen presentation(CAP-independent)in the presence of low-dose IL-2.Therefore,we hypothesized that OX40 signaling might be integral to the TCR-independent phase of murine and human thymic Treg(tTreg)development.Development of tTregs is a two-step process:Strong T-cell receptor(TCR)signals in combination with co-signals from the TNFRSF members facilitate tTreg precursor selection,followed by a TCR-independent phase of tTreg development in which their maturation is driven by IL-2.Therefore,we investigated whether OX40 signaling could also play a critical role in the TCR-independent phase of tTreg development.OX40−/−mice had significantly reduced numbers of CD25−Foxp3low tTreg precursors and CD25+Foxp3+mature tTregs,while OX40L treatment of WT mice induced significant proliferation of these cell subsets.Relative to tTeff cells,OX40 was expressed at higher levels in both murine and human tTreg precursors and mature tTregs.In ex vivo cultures,OX40L increased tTreg maturation and induced CAP-independent proliferation of both murine and human tTregs,which was mediated through the activation of AKT-mTOR signaling.These novel findings show an evolutionarily conserved role for OX40 signaling in tTreg development and proliferation,and might enable the development of novel strategies to increase Tregs and suppress autoimmunity.Prabhakaran Kumar Alejandra Marinelarena Divya Raghunathan Vandhana K Ragothaman Shikha Saini Palash Bhattacharya Jilao Fan Alan L Epstein Ajay V Maker Bellur S Prabhakar 2019Cellular & Molecular Immunology2019,16,2:4
11认知偏差及其对专家证人和法院的影响显示文摘专家证据为法院司法做出了巨大贡献。但是,在对人类思维方式和大脑信息处理过程有所知悉后,我们认识到,专家证据可能会受到情境信息和认知偏差的影响。认知科学能够发现这些潜在的弱点,并提出切实可行的办法来减少它们。Itiel E.Dror Bridget M.McCormack Jules Epstein 王进喜(译) 朱海(译) 2019证据科学2019,27,3:4
12Effects of aging on time course of neovascularization-related gene expression following acute hindlimb ischemia in mice显示文摘neovascularization 的背景分子的分析到响应局部缺血的路线没在老化的上下文被描述的时间联系了基因。我们试图提供老化怎么损害 neovascularization.Methods 幼仔的日益增多地更深的理解(3 月) 并且旧(18 月) C57BI 老鼠受到左 hindlimb 局部缺血。坏死 20 在小牛肌肉被评估。小牛肌肉,外部血,骨头髓在不同时间点被收获。矩阵 metalloproteiniase-9 ( MMPg )的表情, endothelial 氮的氧化物 synthase ( eNOS ),脉管的 endothelial 生长因素( VEGF ), stromal 导出生长 factor-1 ( SDF1 ),组织缺氧可诱导的 factor-1 ( HIF1 ), VEGF receptor-1 ( Fit1 ), VEGF receptor-2 ( Flk1 ), angiopoietin-1 ( Ang1 ), CD133 , CD26 被 RT-PCR 检测或西方的 blotting.White 血房间在外部血被数。基因表达式数据被 variance.Results MMP9, HIF-1 和 SDF-1 的双向分析比较,思考是更多的 upregulated 在老化鼠标在在年老对小的鼠标的尖锐局部缺血期间增加了局部缺血。然而, VEGF 和 eNOS 在年老对小的老鼠展出了更低的表示,尽管有更大的局部缺血紧张。Ang1 和 Flk1 在年老对小的鼠标显示出类似的表示。MMP9 在小对年老的老鼠在外部血更早达到顶点。在老化 bonemarrow 的并发的减少 CD26 和增加的 CD133 表示建议老化损害祖先房间动员,我们的结果显示那的结论缺点的一个复杂数组与变老发生防碍最佳的 neovascularization。这些包括祖先房间的潜在的损害动员到 ischemic 织物,到 ischemia.ZLEr 的 eNOS 和 VEGF 和推迟的回答的减少的层次。王金松,脉管的外科的分割,首先隶属于的医院,孙中山大学,广州,广东 510080,中国(Tel:86-20-87333440.Fax:86-20-87333242。Email:wangjs@mail.sysu.edu.cn ) 这个工作被 NIH RO1 HL085003-01A2 支持, NNSF30100179。WANG Jin-song LIU Xia XUE Zhen-yi Lee Alderman Justin U. Tilan Remi Adenika Stephen E. Epstein Mary Susan Bumett 2011Chinese Medical Journal2011,,7:3
13Prevalence of glaucoma in the Israeli Arab population显示文摘We describe the prevalence and treatment of glaucoma in a Muslim Arab population in Israel. Based on the medical records of 15 122 persons, the overall prevalence of glaucoma was 3.9%. Prevalence rates of primary open angle glaucoma(POAG) and primary angle-closure glaucoma(PACG) were 3.0% and 0.42%, respectively. Prevalence rates of women were 135% that of men considering all types of glaucoma, 143% for POAG, and 96% for PACG. Prostaglandin analogs and beta blockers, alone or combined with carbonic anhydrase inhibitors, were the preferred medications. Of 68 patients who underwent trabeculectomy, 27(39.7%) required medications, postoperatively, for treatment of glaucoma; following Ex-Press shunt surgery, 3/11(27.3%) required medications. During the last three years, 16(1.3%) individuals with POAG were recorded as legally blind as a result of glaucoma.Otzem Chassid Irena Epstein Adi Sharabi-Nov Joseph Pikkel 2018International Journal of Ophthalmology(English edition)2018,11,1:3
14Pulmonary radiation injury显示文摘Benjamin M Raffin Thomas A Epstein Alan H 1997Chest1997,111,4:2
15Diabetes, Hypertension, and Cardiovascular Disease: An Update显示文摘James R. Sowers Murray Epstein Edward D. Frohlich 2001Hypertension: Journal of the American Heart Association2001,,4:2
16发生于乳房假体置入女性的间变性大细胞淋巴瘤:173例临床分析显示文摘背景与目的1962年,首例硅胶乳房假体被成功置人体内。1997年,报道了首例与硅胶乳房假体相关的间变性大细胞淋巴瘤(ALCL)。笔者回顾了已发表的37篇文献报道,共79例患者,并收集了94例未报道的病例。方法复习全世界文献。向作者和主治医师寻求文献或病例中缺少的临床和实验数据。由于需要收集的病例信息很多,有时需要在多个地点获得完整的病例信息。因为不是所有被询问的作者和主治医师均提供了信息,所以造成了数据的不完整。结果ALCL病变首先在假体周围血清肿内发现,其肿块附着于包膜,肿块可侵及皮肤,可在区域淋巴结发生,也可在乳房矫形手术中被发现。临床特点呈现多样化,有的仅表现为细胞学阳性结果,肿块自发消退;有的表现为转移性、难治性肿瘤,甚至死亡。其与假体填充物(盐水或硅胶)和置入假体目的(隆乳或乳房再造)没有相关性。在假体信息完整的病例中,患者体内至少置入过1个毛面假体;18例肿块扩散至包膜外,其中9例是致命的。主要的组织化学标记物是cD-30和Alk-1;其他标记物出现频率较低。乳房假体置入女性发生ALCL的风险评估范围是1/500000—1/3000000。结论与乳房假体相关的ALCL是一种新的淋巴瘤,其起源于瘢痕,具有部位和材料特异性,且临床表现呈现多样化,由多因素引起。Garry S. Brody Dennis Deapen Clive R. Taylor Lauren Pinter-Brown Sarah Rose House-Lightner James S. Andersen Grant Carlson Melissa G. Lechner Alan L. Epstein 朱利娜 高景恒 张晨 袁继龙 2015中国美容整形外科杂志2015,26,12:2
17An experiment of film cooling in a rot ating tran sonic turbine显示文摘Arhari R S Epstein A H 1994Journal of Turbomachinery1994,116,10:2
18单克隆抗体TNT-1的纯化、F(ab)_2片段化及其免疫活性的测定显示文摘TNT-1是-种鼠IgG_2a单抗,已用于肿瘤病人的临床试验。本文将介绍从腹水中进一步纯化TNT-1的方法及制备其F(ah′)_2片段的条件。经Protein A亲和柱层析从小鼠腹水中提取出的lgG,再通过阳离子交换树脂柱Mono S,用缓冲液A(20 mmol/L MES,pH6.3)和缓冲液B(lmol/L NaCI),在快速蛋白液相色层(FPLC)系统上进行梯度洗脱分离,可制得纯净的TNT-1抗体,其免疫活性可达80%~85%;经纯化的TNT-1,用胃蛋白酶消化,制备F(ah′)~2片段,其消化条件是:酶的用量为抗体的1/250,pH3.8,温度37℃,时间4~5 /小时。消化后的混合物,用protein A亲和结合法除去完整的IgG,其余的F(ab′)_2和Fab、Fc等片段,在Mono S柱上,按前述的条件分离。产物TNT-1或F(ah′)_2的免疫活性,用标记抗体和过量抗原结合的方法测定;分高纯化过程中的洗脱峰,用间接免疫荧光技术监测其活性。结果戾明,TNR-1的F(ab′)_2片段的制备是成功的,色层分离纯化的方法简便而有效,并已成功地应用于批量生产。刘长征 F-M Chen Alan L Epstein 1991中山医科大学学报1991,12,4:2
19Immuno-histochemical analysis of Bcl-2, Bax, Bcl-X, and mcl-1 expression in prostate cancers显示文摘Krajewska M Krajewski S Epstein JI 1996Am J Pathol1996,148,:2
20Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency显示文摘Frederick Anokye-Danso Chinmay M. Trivedi Denise Juhr Mudit Gupta Zheng Cui Ying Tian Yuzhen Zhang Wenli Yang Peter J. Gruber Jonathan A. Epstein Edward E. Morrisey 2011Cell Stem Cell2011,,4:2
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