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| 1 | Nerve growth factor and injured peripheral nerve regeneration显示文摘Nerve growth factor (NGF) exhibits many biological activities,such as supply of nutrients,neuroprotection,and the generation and rehabilitation of injured nerves. The neuroprotective and neurotrophic qualities of NGF are generally recognized. NGF may enhance axonal regeneration and myelination of peripheral nerves,as well as cooperatively promote functional recovery of injured nerves and limbs. The clinical efficacy of NGF and its therapeutic potentials are reviewed here. This paper also reviews the latest NGF research developments for repairing injured peripheral nerve,thereby providing scientific evidence for the appropriate clinical application of NGF. | Endong Shi Bingchen Wang Qingshan Sun | 2008 | Neural Regeneration Research2008，3，11： | 10 |
| 2 | Modeling of fixed bed reactor for coal tar hydrogenation via the kinetic lumping approach显示文摘Hydrogenation technology is an indispensable chemical upgrading process for converting the heavy feedstock into favorable lighter products.In this work,a new kinetic model containing four hydrocarbon lumps(feedstock,diesel,gasoline,cracking gas)was developed to describe the coal tar hydrogenation process,the Levenberg–Marquardt’s optimization algorithm was used to determine the kinetic parameters by minimizing the sum of square errors between experimental and calculated data,the predictions from model validation showed a good agreement with experimental values.Subsequently,an adiabatic reactor model based on proposed lumped kinetic model was constructed to further investigate the performance of hydrogenation fixed-bed units,the mass balance and energy balance within the phases in the reactor were taken into accounts in the form of ordinary differential equation.An application of the reactor model was performed for simulating the actual bench-scale plant of coal tar hydrogenation,the simulated results on the products yields and temperatures distribution along with the reactor are shown to be good consistent with the experimental data. | Fei Dai Yalin Zhang Endong Xia Zhanquan Zhang Zhihua Zhang Chunshan Li | 2018 | Carbon Resources Conversion2018，1，3： | 2 |
| 3 | Dynamic-Response Analysis of the Branch System of a Utility Tunnel Subjected to Near-Fault and Far-Field Ground Motions in Different Input Mechanisms显示文摘There are few studies on the dynamic-response mechanism of near-fault and far-field ground motions for large underground structures,especially for the branch joint of a utility tunnel(UT)and its internal pipeline.Based on the theory of a 3D viscous-spring artificial boundary,this paper deduced the equivalent nodal force when a P wave and an SV wave were vertically incident at the same time and transformed the ground motion into an equivalent nodal force using a self-developed MATLAB program,which was applied to an ABAQUS finite element model.Based on near-fault and far-field groundmotions obtained fromtheNGA-WEST2 database,the dynamic responses of a utility tunnel and its internal pipeline in different inputmechanisms of near-fault and far-field groundmotions were compared according to bidirectional input and tridirectional input,respectively.Generally,the damage to the utility tunnel caused by the near-fault ground motion was stronger than that caused by the far-field ground motion,and the vertical ground motion of near-fault ground motion aggravated the damage to the utility tunnel.In addition,the joint dislocation of the upper and lower three-way joints of the pipeline in the branch systemunder the seismic action led to local stress concentrations.In general,the branch system of the utility tunnel had good seismic performance to resist the designed earthquake action and protect the internal pipeline fromdamage during the rare earthquake. | Yuhang Jin Endong Guo Houli Wu Peilei Yan | 2022 | Computer Modeling in Engineering & Sciences2022，，1： | 2 |
| 4 | Expression and localization of Hsps in the heart and blood vessel of heat-stressed broilers显示文摘 | JIMIAN YU ENDONG BAO JIANYAN YAN | 2008 | Cell Stress and Chaperones2008，13，： | 1 |
| 5 | The gap-junction inhibitor carbenoxolone suppresses the differentiation of Th17 cells through inhibition of IL-23 expression in antigen presenting cells显示文摘 | Endong L Shijie J Sonobe Y | 2011 | J Neuroimmunol2011，24，： | 1 |
| 6 | An On-chip Interconnection QoS Verification Platform of Processor of Large Data for Architectural Modeling Analysis显示文摘This paper presents introduction for a QoS verification of on-chip interconnection based on the new progress of the industry, which combined with an AMD processor chip design for big data. Some verification experience in architectural modeling and simulation of on-chip interconnection is also introduced in this paper. | Li Qinghua Qin Jilong Ding Xu Wang Endong Gong Weifeng | 2015 | 国际计算机前沿大会会议论文集2015，，1： | 1 |
| 7 | Neuroprotective effect of deferoxamine on N-methyI-D-aspartate-induced excitotoxicity in RGC-5 cells显示文摘 | Ying Tian Ye He Weitao Song Endong Zhang Xiaobo Xia | 2017 | Acta Biochimica et Biophysica Sinica2017，49，9： | 1 |
| 8 | Chinese traditional medicine and adult neurogenesis in the hippocampus显示文摘 | ZHANG Endong SHEN Jiangang So K F | 2014 | Journal of Traditional and Complementary medicine2014，4，2： | 1 |
| 9 | The gap-junction inhibitor carbenoxolone suppresses the differentiation of Th17 cells through inhibition of IL-23 expression in antigen presenting cells显示文摘 | Endong L Shijie J Sonobe Y | 2011 | J Neuroimmunol2011，24，： | 1 |
| 10 | The growth and capability development of electronics manufacturing service (EMS) companies显示文摘 | Endong Z Yongjiang S Mike G | 2007 | International Journal of Production Economics2007，，107： | 1 |
| 11 | Cellular nanovesicles for therapeutic immunomodulation:A perspective on engineering strategies and new advances显示文摘Cellular nanovesicles which are referred to as cell-derived,nanosized lipid bilayer structures,have emerged as a promising platform for regulating immune responses.Owing to their outstanding advantages such as high biocompatibility,prominent structural stability,and high loading capacity,cellular nanovesicles are suitable for delivering various immunomodulatory molecules,such as small molecules,nucleic acids,peptides,and proteins.Immunomodulation induced by cellular nanovesicles has been exploited to modulate immune cell behaviors,which is considered as a novel cell-free immunotherapeutic strategy for the prevention and treatment of diverse diseases.Here we review emerging concepts and new advances in leveraging cellular nanovesicles to activate or suppress immune responses,with the aim to explicate their applications for immunomodulation.We overview the general considerations and principles for the design of engineered cellular nanovesicles with tailored immunomodulatory activities.We also discuss new advances in engineering cellular nanovesicles as immunotherapies for treating major diseases. | Endong Zhang Philana Phan Zongmin Zhao | 2023 | Acta Pharmaceutica Sinica B2023，13，5： | 1 |
| 12 | The growth and capability development of electronics manufacturing service (EMS) companies 显示文摘 | Zhai Endong Shi Yongjiang Gregory M | 2007 | International Journal of Production Economics2007，107，1： | 1 |
| 13 | Up-regulated microRNA-146a negatively modulate Helicobacter pylori -induced inflammatory response in human gastric epithelial cells显示文摘 | Zhen Liu Bin Xiao Bin Tang Bosheng Li Na Li Endong Zhu Gang Guo Jiang Gu Yuan Zhuang Xiaofei Liu Honglei Ding Xiaoyan Zhao Hong Guo Xuhu Mao Quanming Zou | 2010 | Microbes and Infection2010，，11： | 1 |
| 14 | The effect of transportation on the expression of heat shock proteins and meat quality of M. longissimus dorsi in pigs显示文摘 | Jimian Yu Shu Tang Endong Bao Miao Zhang Qingqing Hao Zhenghua Yue | 2009 | Meat Science2009，，3： | 1 |
| 15 | Transportation Stress and Expression of Heat Shock Protein Affecting Pork Quality 显示文摘 | TANG Shu BAO Endong Sultan K R | 2014 | Pakistan Veterinary Journal2014，34，1： | 1 |
| 16 | Numerical Simulation of the Seismic Response of a Horizontal Storage Tank Based on a SPH-FEM Coupling Method显示文摘A coupled numerical calculation method combining smooth particle hydrodynamics(SPH)and the finite element method(FEM)was implemented to investigate the seismic response of horizontal storage tanks.Anumericalmodel of a horizontal storage tank featuring a free liquid surface under seismic action was constructed using the SPH–FEM coupling method.The stored liquid was discretized using SPH particles,while the tank and supports were discretized using the FEM.The interaction between the stored liquid and the tank was simulated by using the meshless particle contact method.Then,the numerical simulation results were compared and analyzed against seismic simulation shaking table test data to validate the method.Subsequently,a series of numerical models,considering different liquid storage volumes and seismic effects,were constructed to obtain time history data of base shear and top center displacement,which revealed the seismic performance of horizontal storage tanks.Numerical simulation results and experimental data showed good agreement,with an error rate of less than 18.85%.And this conformity signifies the rationality of the SPH-FEM coupling method.The base shear and top center displacement values obtained by the coupled SPH-FEM method were only 53.3% to 69.1% of those calculated by the equivalent mass method employed in the current code.As the stored liquid volume increased,the seismic response of the horizontal storage tank exhibited a gradual upward trend,with the seismic response increasing from 73% to 388% for every 35% increase in stored liquid volume.The maximum von Mises stress of the tank and the supports remained below the steel yield strength during the earthquake.The coupled SPH-FEM method holds certain advantages in studying the seismic problems of tanks with complex structural forms,particularly due to the representation of the flow field distribution during earthquakes by involving reservoir fluid participation. | Peilei Yan Endong Guo HouliWu Liangchao Zhang | 2024 | Computer Modeling in Engineering & Sciences2024，139，5： | 0 |
| 17 | Flexible triboelectric nanogenerator toward ultrahigh-frequency vibration sensing显示文摘Flexible high-frequency vibration sensors are highly desirable in various real-world applications such as structural health monitoring,environmental monitoring,and the internet of things.However,developing a facile and effective method to fabricate vibration sensors simultaneously featuring high vibration frequency response-ability and flexibility remains a grand challenge.Herein,we report a flexible ultrahigh-frequency triboelectric vibration sensor(UTVS)prepared by a layer-particle-layer structure.Owing to the flexibility of the materials(i.e.,polyethylene terephthalate membrane)and the ultrahigh-frequency vibration response-ability of internal microparticles,the flexible UTVS exhibits an enhanced working frequency range of 3–170 kHz,which is much broader than previously reported triboelectric vibration sensors.Moreover,the UTVS can work not only in a flat state but also in a bent state due to its flexibility and the unique layer-particle-layer structural design.The UTVS shows nanometer-level vibration response-ability,omnidirectional response,stability in the temperature range of 10–70°C,good frequency resolution of 0.01 kHz,and excellent performance in burst vibration detection(e.g.,pencil lead break events and impact events from falling steel balls).With a collection of compelling features,the device is successfully demonstrated in vibration monitoring of curved structures(e.g.,real-time water pipeline leak monitoring).Such a flexible ultrahigh-frequency triboelectric vibration sensor holds great potential in a wide range of practical applications,such as communication,health care,and infrastructure monitoring. | Zhiwei Lin Chenchen Sun Gaoqiang Zhang Endong Fan Zhihao Zhou Ziying Shen Jun Yang Mingyang Liu Yushu Xia Shaobo Si Jin Yang | 2022 | Nano Research2022，15，8： | 0 |
| 18 | Adversarial attack and defense in reinforcement learning-from AI security view显示文摘Reinforcement learning is a core technology for modern artificial intelligence,and it has become a workhorse for AI applications ranging from Atrai Game to Connected and Automated Vehicle System(CAV).Therefore,a reliable RL system is the foundation for the security critical applications in AI,which has attracted a concern that is more critical than ever.However,recent studies discover that the interesting attack mode adversarial attack also be effective when targeting neural network policies in the context of reinforcement learning,which has inspired innovative researches in this direction.Hence,in this paper,we give the very first attempt to conduct a comprehensive survey on adversarial attacks in reinforcement learning under AI security.Moreover,we give briefly introduction on the most representative defense technologies against existing adversarial attacks. | Tong Chen Jiqiang Liu Yingxiao Xiang Wenjia Niu Endong Tong Zhen Han | 2019 | Cybersecurity2019，2，1： | 0 |
| 19 | Unexpected Photocatalytic Degeneration of NAD^(+) for Inducing Apoptosis of Hypoxia Cancer Cells显示文摘Developing customized chemical reactions that could regulate a specific biological process on demand is regarded as an advanced and promising strategy for treating diseases.However,conventional chemical reactions become challenging in complex physiological environments,which demand mild reaction conditions,high efficiency,good biocompatibility,and strong controllability.Moreover,the effects of the achieved reactions on the real biological system are usually further lessened.Herein,we describe an advanced photocatalytic reaction that irreversibly converted nicotinamide adenine dinucleotide(NAD+)to nicotinamide and adenosine diphosphate(ADP)-ribose by the cationic conjugated poly(fluorene-co-phenylene)(PFP).This reaction was introduced to tumor cells and triggered cell apoptosis.Under white-light illumination,the photocatalytic reaction decreased the NAD+ratio in tumor cells,disrupted the mitochondrial membrane potential,inhibited the synthesis of adenosine triphosphate(ATP),and effectively induced apoptosis.We propose a mechanism of the reaction where PFP is photoexcited to PFP*,and the obtained photoelectrons are transferred from PFP*to NAD+to produce nicotinamide and another unstable intermediate,ADP-ribosyl radical.ADP-ribosyl radical quickly reacts with triethanolamine to form ADP-ribose.This intracellular utilization of a specific photocatalytic reaction could offer a new approach to affect biological function for efficient cancer treatment. | Shengpeng Xia Haotian Bai Endong Zhang Wen Yu Zhiqiang Gao Fengting Lv Yiming Huang Daoben Zhu Shu Wang | 2023 | CCS Chemistry2023，5，10： | 0 |
| 20 | Shaking table test study on performance and functionality of a typical telecommunication room after earthquakes显示文摘Large numbers of basic transceiver stations,where the telecommunication room is one of the main components,comprise an important part of the telecommunication system.After earthquakes,considerable economic loss from telecommunication systems is often associated with seismic damage and functional loss of the telecommunication room.However,research related to this has been limited.In this study,shaking table tests were conducted for a full-scale typical telecommunication room,including a light-steel house and the necessary communication and power supply equipment.The tests not only focused on the seismic damage to all the structures but also considered the functions of the communication and power supply of the equipment.The interactions between these facilities and their effects on communication function were also investigated.Compared with the damage to structures,the interruption of the power supply due to earthquakes is a weak link.Finally,the damage indexes,together with their threshold values of different damage states for the communication and power supply equipment,were derived from the test results.The results of this research can contribute to the literature gaps regarding seismic performance studies of telecommunication rooms,and can serve as a valuable reference for future research on its seismic fragility and economic losses evaluation. | Li Bo Guo Endong Sun Guoliang Ji Shuqiang Mao Chenxi Wang Tao Han Di Li Xiaofei | 2024 | Earthquake Engineering and Engineering Vibration2024，23，2： | 0 |
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