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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | 等离子喷涂复合涂层结构对力学性能影响的有限元分析:网状孔隙结构的影响显示文摘本研究的目的是进一步理解等离子喷涂制备的复合涂层在外力作用下内部应力场的规律。目前,相关方面的报道较少。为了达到这个目的,采用扫描电镜获得高分辨率的涂层照片,经过离散化处理,并进行有限元分析。Al2O3-13TiO2等离子喷涂涂层是一个比较理想的研究目标。通过调整喷涂参数获得了不同的多孔结构,例如孔隙率、裂纹密度、裂纹方向等。数值模拟显示网状孔隙结构对涂层内应力场有显著的影响。同样的,通过改变相的本征力学属性,研究了其它成分的涂层。在理想状态下,仿真结果显示第二相对涂层内部应力场的影响较弱。另外,提出了一种通用的涂层性能分析方法,指出了它的优点和局限性,并强调其重要性(REV)。 | C. Palaccio Espinosa G. Antou, A A, Denoirjean G. Montavon 王辉(译) | 2010 | 热喷涂技术2010，，4： | 2 |
| 3 | A phase Ⅱ trial of cisplatin and vinorelbine in patients with recurrent or metastatic squamous cell carcinoma of the head and neck显示文摘 | Espinosa E Zamora P Milla A | 2002 | Head Neck2002，24，12： | 1 |
| 4 | High ALTlevel predict viremia in anti-HCV-positive HD patients if a modi-fied normal range of ALT is applied显示文摘 | Espinosa M Martin-Malo A Alvarez de Lara MA | 2000 | Clin Nephrol2000，54，2： | 1 |
| 5 | Determi- nation of tetracyclines in milk samples by magnetic solid phase extraction flow injection analysis 显示文摘 | Rodriguez J A Espinosa J Aguilar-Arteaga K | 2010 | Microchim Acta2010，171，84： | 1 |
| 6 | MRI features of mucosa-associated lymphoid tissue lymphoma in the breast显示文摘 | ESPINOSA L A DANIEL B L JEFFREY S S | | 0，，01： | 1 |
| 7 | Identification of a gene,MLL,that spans the breakpoint in 11q23 translocations associated with human leukemias显示文摘 | Ziemin-Van Der Poel S McCabe NR Gill HJ Espinosa R 3rd Patel Y Harden A Rubinelli P Smith SD LeBeau MM Rowley JD | | 0，，： | 1 |
| 8 | Characterisation of dusts and sludges generated during stainless steel production in brazilian industries 显示文摘 | Nolasco-Sobrinho P J Espinosa D C R Tenorio J A S | 2003 | Iron- making and steelmaking2003，30，1： | 1 |
| 9 | Performance of nanocrystalline graphite field emitters显示文摘 | Busta H H Espinosa R J Rakhimov A T Suetin N V | 2001 | Solid State Electronics2001，，45： | 1 |
| 10 | An overview on the current processes for the recycling of batte - ries 显示文摘 | Espinosa D C R Bemardes A M Teno6rio J A S | 2004 | Journal Power Sources2004，135，： | 1 |
| 11 | Thermal behavior of chro- mium electroplating sludge显示文摘 | ESPINOSA D C R TEN RIO J A S | 2001 | Waste Management2001，21，4： | 1 |
| 12 | Alternative Nuclear Functions forNF-Kappab Family Members显示文摘 | ESPINOSA L BIGAS A MULERO M C | 2011 | Am J Cancer Res2011，1，4： | 1 |
| 13 | Increased expression of the novel proinflammatory cytokine high mobility group box chromosomal protein 1 in skin lesions of patients with lupus erythematosus显示文摘 | Popovic K Ek M Espinosa A | 2005 | Arthritis Rheum2005，52，11： | 1 |
| 14 | Simple but Effective Ferrocene Derivative as aRedox, Colorimetric,and Fluorescent Receptor forHighly Selective Recognition of Zn2+ Ions 显示文摘 | ZAPATA F CABALLERO A ESPINOSA A etal | 2007 | OrgLett2007，，9： | 1 |
| 15 | Analysis of histological change of tendinous grafts in reconstruc- tion of the dorsal wrist ligament显示文摘 | Espinosa - Gutierrez A Villegas - Castrejon H Sanchez - Gutierrez LE | 2008 | Acta Ortop Mex2008，1，： | 1 |
| 16 | A computer model for teaching the dynamic behavior of AC contac- tors显示文摘 | RUIZ J R ESPINOSA A G ROMERAL L | 2010 | IEEE Transactions on Education2010，53，2： | 1 |
| 17 | Thermal behavior of chromi-um electroplating sludge显示文摘 | ESPINOSA D C R TEN6RI0 J A S | 2001 | Waste Manage2001，21，4： | 1 |
| 18 | Impaired mitogenic response of peripheral blood T cell in ulcerative colitis is not due to apoptosis显示文摘 | PEREZ-MACHADO M A ESPINOSA L M de la MADRGAL E J | 1999 | Dig Dis Sci1999，44，5： | 1 |
| 19 | Monitoring of heavy metals in topsoils,atmospheric particles and plant leaves to identify possible contamination sources显示文摘 | Rossini Oliva S Fernandez Espinosa A J | 2007 | Microchemical Journal2007，86，1： | 1 |
| 20 | Adventitious shoot regeneration and rooting of Prunus serotina in vitro vultures显示文摘 | ESPINOSA A C PIJUT P M MICHLER C H | 2006 | Hort Science2006，41，1： | 1 |
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