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| 1 | 长茎葡萄蕨藻培养条件的研究显示文摘为研究长茎葡萄蕨藻的培养条件,通过温度、光照、盐度以及不同营养盐(硝酸钠NaNO_3、硝酸铵NH_4NO_3、尿素CO(NH_2)_2、碳酸氢铵NH_4HCO_3)四个方面探索对长茎葡萄蕨藻生长的影响。结果表明,长茎葡萄蕨藻适宜的温度范围为21~27℃,最适温度为27℃,在此温度条件下其相对生长率(RGR)最大为3.63%·d^(-1);适宜的光照范围为72.73~145.45μmol·m^(-2)s^(-1),最适光照为109.09~145.45μmol·m^(-2)s^(-1),2个光照强度下,相对生长率差异不显著;最适的盐度范围为27.5~32.5‰,随盐度的继续升高,长茎葡萄蕨藻RGR呈下降趋势。通过4种不同营养盐(NaNO_3、NH_4NO_3、CO(NH_2)_2、NH_4HCO_3)的培养实验得出,其最适浓度分别为10~20mg·L^(-1)、10~20mg·L^(-1)、10~30mg·L^(-1)、10~30mg·L^(-1)。不同营养盐的对比结果显示,硝酸盐(硝酸钠NaNO_3、硝酸铵NH_4NO_3)更能促进长茎葡萄蕨藻的生长;浓度为20mg·L^(-1 )NH_4NO_3条件下,长茎葡萄蕨藻的相对生长率(RGR)最高。 | 王海阳 唐贤明 金月梅 Maria Dyah Nur Meinita 池姗 刘涛 | 2017 | 海洋湖沼通报2017，，6： | 7 |
| 2 | Chemopreventive effect of apple and berry fruits against colon cancer显示文摘Colon cancer arises due to the conversion of precancerous polyps(benign)found in the inner lining of the colon.Prevention is better than cure,and this is very true with respect to colon cancer.Various epidemiologic studies have linked colorectal cancer with food intake.Apple and berry juices are widely consumed among various ethnicities because of their nutritious values.In this review article,chemopreventive effects of these fruit juices against colon cancer are discussed.Studies dealing with bioavailability,in vitro and in vivo effects of apple and berry juices are emphasized in this article.A thorough literature survey indicated that various phenolic phytochemicals present in these fruit juices have the innate potential to inhibit colon cancer cell lines.This review proposes the need for more preclinical evidence for the effects of fruit juices against different colon cancer cells,and also strives to facilitate clinical studies using these juices in humans in large trials.The conclusion of the review is that these apple and berry juices will be possible candidates in the campaign against colon cancer. | Saravana Kumar Jaganathan Muthu Vignesh Vellayappan Gayathri Narasimhan Eko Supriyanto Dyah Ekashanti Octorina Dewi Aqilah Leela T Narayanan Arunpandian Balaji Aruna Priyadarshini Subramanian Mustafa Yusof | 2014 | World Journal of Gastroenterology2014，20，45： | 3 |
| 3 | 冷冻保护剂对牛精子功能和渗透压的影响显示文摘本文验证了一个假设:在精子中添加和去除冷冻保护剂可能导致精子的调节容量减少,渗透物质损失,精子功能降低。不进行冷冻和解冻的情况下,常用的冷冻保护剂可以降低培养基中牛精子的总活力和前进运动力,降低精子通过宫颈粘液的能力,破坏精子头膜,并导致精子尾巴卷曲。如果在很多小的步骤中而非仅在一个步骤中添加和去除冷冻保护剂,可适当保护精子的功能。特定的冷冻保护剂能降低细胞内的左旋肉碱和谷氨酸的浓度,而不是肌醇和山梨醇的浓度。在多步中添加或者去除冷冻保护剂比在一步中进行好,因为粘液的渗透依赖于精子中原始细胞内左旋肉碱和谷氨酸的总量。总之,在多步中添加或者去除丙三醇和丙二醇可以最好地保持精子的质量。因为丙三醇和丙二醇与降低的细胞内谷氨酸浓度有关。在牛精子中,谷氨酸看来可以调控冷冻保护剂导致的细胞膨胀。 | Erif E. M. Setyawan Trevor G. Cooper Dyah A. Widiasih Aris Junaidi Ching-Hei Yeung | 2009 | Asian Journal of Andrology2009，11，5： | 3 |
| 4 | Multivariate Process Variability Monitoring显示文摘 | Maman A. Djauhari Muhammad Mashuri Dyah E. Herwindiati | 2008 | Communications in Statistics - Theory and Methods2008，，11： | 1 |
| 5 | Frequency of Shiga toxin-producing Escherichia coli in cattle at a breeding farm and at a slaughterhouse in Japan显示文摘 | Kunihiro Shinagawa Masahiko Kanehira Katsuhiko Omoe Ibuki Matsuda Dong-Liang Hu Dyah Ayu Widiasih Shunji Sugii | 2000 | Veterinary Microbiology2000，，3： | 1 |
| 6 | Information quality improvement model on hospital information system using six sigma显示文摘 | DYAH D R KRIDANTO S | 2013 | Procedia Technol2013，9，： | 1 |
| 7 | Comparison of sulfuric and hydrochloric acids as catalysts in hydrolysis of Kappaphycus alvarezii (couonii ) 显示文摘 | MARIA DYAH NUR MEINITA YONG KI HONG GWI TAEK JEONG | 2012 | Bioprocess Biosyst Eng2012，38，： | 1 |
| 8 | Reprogramming of Mouse and Human Cells to Pluripotency Using Mature MicroRNAs显示文摘 | Norikatsu Miyoshi Hideshi Ishii Hiroaki Nagano Naotsugu Haraguchi Dyah Laksmi Dewi Yoshihiro Kano Shinpei Nishikawa Masahiro Tanemura Koshi Mimori Fumiaki Tanaka Toshiyuki Saito Junichi Nishimura Ichiro Takemasa Tsunekazu Mizushima Masataka Ikeda Hirofumi | 2011 | Cell Stem Cell2011，，6： | 1 |
| 9 | An approach of sustainable development: rural re- vitalization as the pioneer of OVOP movement显示文摘 | Dyah Savitri | 2008 | Journal of OVOP Policy2008，1，7： | 1 |
| 10 | Reprogramming of Mouse and Human Cells to Pluripotency Using Mature MicroRNAs显示文摘 | Norikatsu Miyoshi Hideshi Ishii Hiroaki Nagano Naotsugu Haraguchi Dyah Laksmi Dewi Yoshihiro Kano Shinpei Nishikawa Masahiro Tanemura Koshi Mimori Fumiaki Tanaka Toshiyuki Saito Junichi Nishimura Ichiro Takemasa Tsunekazu Mizushima Masataka Ikeda Hirofumi | 2011 | Cell Stem Cell2011，，6： | 1 |
| 11 | Effect of in vivo administration of reprogramming factors in the mouseliver显示文摘 | Akira Tomokuni Hidetoshi Eguchi Hiromitsu Hoshino Dyah Dewi Shinpei Nishikawa Yoshihiro Kano Norikatsu Miyoshi Arinobu Tojo Seiichiro Kobayashi Noriko Gotoh Kunihiko Hinohara Noemi Fusaki Toshiyuki Saito Hiroshi Suemizu Hiroshi Wada Shogo Kobayashi Shiger | 2013 | Oncology Letters2013，，2： | 1 |
| 12 | Mathematical modeling of the development of antioxidant activity in soybeans fermented with Aspergillus oryzae and Aspergillus awamori in the solid state 显示文摘 | Dyah Hesti Wardhani Jose Antonio Vazquez Severino S Pandiella | 2008 | Journal of Agricultural and Food Chemistry2008，，： | 1 |
| 13 | Optimization of antioxidants extraction from soybeans fermented by Aspergillus oryzae显示文摘 | DYAH H WARDHANI JOSE A | 2010 | Food Chem2010，118，3： | 1 |
| 14 | Endothelial Cell–Derived Endothelin-1 Promotes Cardiac Fibrosis in Diabetic Hearts Through Stimulation of Endothelial-to-Mesenchymal Transition显示文摘 | Bambang Widyantoro Noriaki Emoto Kazuhiko Nakayama Dyah W. Anggrahini Suko Adiarto Naoko Iwasa Keiko Yagi Kazuya Miyagawa Yoshiyuki Rikitake Takashi Suzuki Yaz Y. Kisanuki Masashi Yanagisawa Ken-ichi Hirata | 2010 | Circulation2010，，22： | 1 |
| 15 | 海啸灾害后印度尼西亚班达阿齐市的土地覆盖变化与海岸带区域规划(英文)显示文摘2004年12月26日,由于欧亚板块的碰撞,40年以来最大的地震灾害发生在印度洋。地震诱发的海啸影响到Nangroe Aceh Darussalam省的许多城市,包括省会城市班达阿齐。在这地区共有超过12万人死亡,100万人无家可归。基于遥感数据的分析表明,有12万亩的土地受到了灾害。在班达阿齐市,鱼塘、住宅用地和保护区的变化是这一地区最显著的土地利用/覆盖变化,受灾前后这些用地类型的面积相应的变化了61.5%、57.8%和77.6%。目前,印度尼西亚中央政府正在计划一个新的海岸带土地利用规划,在原来密集的海岸带建立一个缓冲区(约距海岸带2 km)。政府已经要求许多海岸带的社区代表与非政府组织参与到决策的过程中。为了选择并采取最佳的土地利用方式,海啸灾害后的海岸带规划应该包括一些重要的基本要素。本研究主要关注作为该省社会经济活动中心的班达阿齐市。检测了由于海啸灾害造成的土地利用/覆盖变化(包括物理破坏),特别是农业用地和居住区用地的变化,并且分析了受灾村落的不同类型及灾害对社会经济活动造成的影响。此外,还为政府以及当地居民在灾后的规划中选择更为可持续的空间布局方案提出了建议。 | Ernan Rustiadi Dyah R.Panuju B.H.Trisasongko Ruchyat Deni Djakapermana | 2006 | 地球科学进展2006，21，2： | 1 |
| 16 | Bioprospecting for anti-Streptococcus mutans:The activity of 10% Sesbania grandiflora flower extract comparable to erythromycin显示文摘Objective:To search an herbal material,capable of inhibiting plaque producing bacteria Streptococcus mutans.Methods:Twenty materials comprising 10 flowers and 10 rhizomes were extracted with70% ethanol.Their activity was then examined at a concentration of 10%(w/v) against Streptococcus mutans in vitro on Mueller–Hinton media.Erythromycin(Oxoid,20 mg disc) was used as a positive control.Meanwhile,to establish a fingerprint guide for authentication or quality control,the most potent material was further analyzed regarding its chemical constituents by means of reversed phase-high performance liquid chromatography(HPLC) and thin-layer chromatography(TLC).Results:Of the tested samples,Sesbania grandiflora(S.grandiflora) flower and Costus speciosus rhizome extracts showed the most potent activity with inhibited zone diameters of 18.5 and 14.8 mm,respectively.On the other hand,other extract plants showed a diameter zone in the range of 0.5–10.6 mm or being inactive(diameter=0 mm).The activity of S.grandiflora was comparable to that of erythromycin(diameter=18.0 mm).The best separation was achieved on HPLC system with acetonitrile-water with a ratio of2:8,and a flow rate at 0.5 m L/min.TLC,meanwhile,was featured on chloroform–methanol(8.5:1.5) as a mobile system.Conclusions:S.grandiflora flower is a promising material to be developed as the active ingredient of anti-plaque toothpaste as well as mouthwash solution.The developed HPLC and TLC system can be used for a further standard in its material authentication as well as for a fingerprinting of quality control during the manufacturing process. | Azis Saifudin Alfian Mahardika Forentin Arini Fadhilah Kuswandi Tirtodiharjo Witri Dyah Melani Devita Widyasari Tri Agus Saroso | 2016 | Asian Pacific Journal of Tropical Biomedicine2016，6，9： | 0 |
| 17 | 酪醇通过提高糖尿病高糖环境下骨骼肌细胞的活力和旁分泌功能促进糖尿病小鼠缺血下肢的血管新生显示文摘目的下肢缺血性疾病(HLI)是糖尿病的主要并发症之一,治疗的关键是体内血管重构。但由于糖尿病伴随持续的高血糖,机体发生系统性损伤,血管新生能力被严重破坏,所以阻碍了治疗性血管新生促糖尿病血管重构的作用。骨骼肌细胞(SMC)分泌血管新生因子,通过细胞间交流在血管重构中发挥重要作用。但在HLI的糖尿病病理条件下(高糖、低氧),骨骼肌细胞功能受损,导致SMC的促血管新生作用下降。小分子化合物酪醇(TYR)具有细胞保护和抗氧化的作用,但在高糖环境中,其对SMC的保护和促血管新生作用仍是未知的。方法将骨骼肌细胞分为3组:对照、高糖、高糖+TYR。利用MTIT法、细胞内活性氧(ROS)检测法和流式细胞术细胞凋亡检测法等考察TYR对SMC细胞活力和凋亡的影响;利用Western Blotting和ELISA考察TYR对血管新生因子(VEGF-A和PDGF-BB)表达和分泌的作用;EdU和transwell实验观察SMC细胞分泌物对血管内皮细胞(HUVECs)和血管平滑肌细胞(MOVAS)增殖和迁移的影响;体内实验通过构建糖尿病下肢缺血小鼠模型,肌肉注射TYR,应用激光多普勒扫描仪分析糖尿病下肢缺血小鼠下肢血流恢复情况,考察酪醇对糖尿病下肢缺血小鼠的治疗作用。结果(1)TYR抑制了高血糖诱导的细胞内活性氧(ROS)水平,降低了细胞凋亡率,提高了SMC细胞活力;(2)TYR促进了高糖环境中SMC细胞VEGF-A和PDGF-BB的表达和分泌;(3)TYR预处理SMC后收集到的条件培养基促进了HUVECs和MOVAS的增值和迁移;(4)TYR改善了糖尿病下肢缺血模型小鼠的血管新生和血流恢复功能。结论用TYR处理SMC可显著提高骨骼肌的细胞活力和旁分泌功能,促进缺血组织中血流恢复和血管新生。研究结果提示对于糖尿病下肢缺血疾病,酪醇是一种具有潜在应用价值的促进血管新生作用的小分子化合物。 | 张建琪 Olivia Marcelina Dyah Ari Nugrahaningrum 徐志玲 刘才平 王贵学 吴寿荣 江启慧 | 2019 | 医用生物力学2019，34，A01： | 0 |
| 18 | Salidroside Pretreatment to Mesenchymal Stem Cells Improves Cell Survival and Migration to Promote Diabetic Wound Healing显示文摘Objective Diabetic patients pose a greater challenge in managing chronic wound healing,leading to a higher amputation risk compared to non-diabetic patients.Due to their paracrine function by secreting various cytokines and angiogenic factors,mesenchymal stem cells(MSCs)have been acknowledged to be a potential agent in modulating wound healing process.However,post-transplanted MSCs are vulnerable to death,indicating poor survival and migration ability in the wound site of the host,especially under hyperglycemia.As hyperglycemia induces reactive oxygen species(ROS)generation and cellular apoptosis,improvement of MSCs survival and migration potentials under hyperglycemia could contribute to a more efficient MSCs-based wound healing therapy.Salidroside(Sa),a small-molecule drug derived from Rhodiola plant,has been proved to enhance the paracrine function of skeletal muscle cells,as well as their migration even under hypoxichyperglycemia.Herein,we investigated whether Sa could improve the survival and migration potentials of MSCs,subsequently enhance the wound healing process under hyperglycemia.Methods MSCs were cultured under three conditions:low glucose,high glucose,and high glucose+Sa.qPCR analysis and western blotting were done to examine the mRNA and protein expression level of several factors which are important in upregulating the wound healing process.MTT colorimetric assay,intracellular ROS detection,and flow cytometry assay were employed to examine the effect of Sa in MSCs survival.Transwell chamber assay,scratch assay,and phalloidin staining were done to elucidate the role of Sa in regulating MSCs migration potential.For in vivo experiment,diabetic wound healing mice model was generated to elucidate the effect of Sa-pretreated MSCs transplantation in wound closure rate,as well as re-epithelization status,observed with hematoxylin and eosin staining.The diabetic wound healing mice model were divided into three groups:1)mice injected with PBS,2)mice transplanted with PBS-pretreated MSCs,and 3)mice transplanted with Sa-pretreated MSCs.Results(1)Hyperglycemic condition induced the generation of ROS and suppressed total cell number of MSCs,while Sa treatment into MSCs restored these hyperglycemia-induced alterations.In line with this,total apoptotic cells were also suppressed by treating MSCs with Sa.The expression level of cell survival factor,heme-oxygenase 1(HO-1),was enhanced in Sa-pretreated MSCs.Further treatment of HO-1 inhibitor into Sa-pretreated MSCs nullified the ROS level and total apoptotic cells,indica-ting the importance of HO-1 in mediating the Sa-induced survival of MSCs under hyperglycemia.(2)Transwell chamber and scratch assay results showed that Sa-pretreated MSCs have a higher migration potential under hyperglycemia,supported by higher F-actin polymerization fractal dimension.Fibroblast growth factor 2(FGF2)and hepatocyte growth factor(HGF)expression level,which are essential factors for cell migration,were also improved in Sa-pretreated MSCs under hyperglycemia.(3)In diabetic wound healing mice model,transplantation of Sa-pretreated MSCs resulted in significantly improved wound closure rate and re-epithelization.The protein levels of HO-1,FGF2,and HGF were also enhanced in the tissues obtained from the wound site of diabetic wound healing mice model which were transplanted with Sa-pretreated MSCs.Conclusions Salidroside pretreatment on MSCs could improve their survival and migration potentials,subsequently promoting wound healing process under hyperglycemia.This prospective MSC-based therapy could serve as a novel strategy to improve diabetic wound healing. | Olivia Marcelina Jianqi Zhang Dyah Ari Nugrahaningrum Zhiling Xu Guixue Wang Li Yang Shourong Wu Vivi Kasim | 2019 | 医用生物力学2019，34，A01： | 0 |
| 19 | Robust Classification of Remote Sensing Data for Green Space Analysis显示文摘 | Dyah E. Herwindiati Maman A. Djauhari Luan Jaupi | 2013 | Journal of Mathematics and System Science2013，3，4： | 0 |
| 20 | Analysis of International Migrant Workers: Case Study of Worker of Madura Origin显示文摘 | R. M. Moch. Wispandono Nety Dyah Kurniasari Deny S. B. Yuherawan | 2018 | Management Studies2018，6，5： | 0 |
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