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| 1 | Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines显示文摘SARS-CoV-2 variants could induce immune escape by mutations on the receptor-binding domain(RBD)and N-terminal domain(NTD).Here we report the humoral immune response to circulating SARS-CoV-2 variants,such as 501Y.V2(B.1.351),of the plasma and neutralizing antibodies(NAbs)elicited by CoronaVac(inactivated vaccine),ZF2001(RBD-subunit vaccine)and natural infection.Among 86 potent NAbs identified by high-throughput single-cell VDJ sequencing of peripheral blood mononuclear cells from vaccinees and convalescents,near half anti-RBD NAbs showed major neutralization reductions against the K417N/E484K/N501Y mutation combination,with E484K being the dominant cause.VH3-53/VH3-66 recurrent antibodies respond differently to RBD variants,and K417N compromises the majority of neutralizing activity through reduced polar contacts with complementarity determining regions.In contrast,the 242–244 deletion(242–244Δ)would abolish most neutralization activity of anti-NTD NAbs by interrupting the conformation of NTD antigenic supersite,indicating a much less diversity of anti-NTD NAbs than anti-RBD NAbs.Plasma of convalescents and CoronaVac vaccinees displayed comparable neutralization reductions against pseudo-and authentic 501Y.V2 variants,mainly caused by E484K/N501Y and 242–244Δ,with the effects being additive.Importantly,RBD-subunit vaccinees exhibit markedly higher tolerance to 501Y.V2 than convalescents,since the elicited anti-RBD NAbs display a high diversity and are unaffected by NTD mutations.Moreover,an extended gap between the third and second doses of ZF2001 leads to better neutralizing activity and tolerance to 501Y.V2 than the standard three-dose administration.Together,these results suggest that the deployment of RBD-vaccines,through a third-dose boost,may be ideal for combating SARS-CoV-2 variants when necessary,especially for those carrying mutations that disrupt the NTD supersite. | Yunlong Cao Ayijiang Yisimayi Yali Bai Weijin Huang Xiaofeng Li Zhiying Zhang Tianjiao Yuan Ran An Jing Wang Tianhe Xiao Shuo Du Wenping Ma Liyang Song Yongzheng Li Xiang Li Weiliang Song Jiajing Wu Shuo Liu Xuemei Li Yonghong Zhang Bin Su Xianghua Guo Yangyang Wei Chuanping Gao Nana Zhang Yifei Zhang Yang Dou Xiaoyu Xu Rui Shi Bai Lu Ronghua Jin Yingmin Ma Chengfeng Qin Youchun Wang Yingmei Feng Junyu Xiao Xiaoliang Sunney Xie | 2021 | Cell Research2021，31，7： | 12 |
| 2 | Salvianolic acid A alleviates renal injury in systemic lupus erythematosus induced by pristane in BALB/c mice显示文摘The purpose of this study was to investigate the effects of salvianolic acid A(SAA) in systemic lupus erythematosus(SLE) induced by pristane in BALB/c mice.Lupus mice were established by confirming elevated levels of autoantibodies and IL-6 after intraperitoneal injection of pristane.Mice were then treated with daily oral doses of SAA for 5 months in parallel with mice treated with prednisone and aspirin as positive controls.The levels of autoantibodies were monitored at monthly intervals and nephritic symptoms observed by hematoxylin and eosin(H&E) and periodic acid-Schiff(PAS) staining.Western blot analysis of renal tissue was also employed.SAA treatment caused a significant reduction in the levels of anti-Sm autoantibodies and reduced renal histopathological changes and pathological effects.SAA treatment also significantly inhibited the phosphorylation of IKK,IκB and NFκB in renal tissues of lupus mice.In conclusion,the results suggest that SAA alleviates renal injury in pristane-induced SLE in BALB/c mice through inhibition of phosphorylation of IKK,IκB and NFκB. | Yihuang Lin Yu Yan Huifang Zhang Yucai Chen Yangyang He Shoubao Wang Lianhua Fang Yang Lv Guanhua Du | 2017 | Acta Pharmaceutica Sinica B2017，7，2： | 8 |
| 3 | Diagnosis of CO2 dynamics and fluxes in global coastal oceans显示文摘Global coastal oceans as a whole represent an important carbon sink but,due to high spatial–temporal variability,a mechanistic conceptualization of the coastal carbon cycle is still under development,hindering the modelling and inclusion of coastal carbon in Earth SystemModels.Although temperature is considered an important control of sea surface pCO2,we show that the latitudinal distribution of global coastal surface pCO2 does not match that of temperature,and its inter-seasonal changes are substantially regulated by non-thermal factors such as watermassmixing and net primary production.These processes operate in both ocean-dominated and river-dominated margins,with carbon and nutrients sourced from the open ocean and land,respectively.These can be conceptualized by a semi-analytical framework that assesses the consumption of dissolved inorganic carbon relative to nutrients,to determine how a coastal system is a CO2 source or sink.The framework also finds utility in accounting for additional nutrients in organic forms and testing hypotheses such as using Redfield stoichiometry,and is therefore an essential step toward comprehensively understanding and modelling the role of the coastal ocean in the global carbon cycle. | Zhimian Cao Wei Yang Yangyang Zhao Xianghui Guo Zhiqiang Yin Chuanjun Du Huade Zhao Minhan Dai | 2020 | National Science Review2020，7，4： | 5 |
| 4 | 3-1 Transmission Electron Microscopy Investigations of Bubble Formation in Grain Boundaries of He-implanted Polycrystalline SiC显示文摘Because of the low cross-section for neutron capture and its excellent structural, chemical and mechanical stability, silicon carbide (SiC) is an important material with application in the development of nuclear energy and waste technologies. For example, in the fourth generation of fission reactors, such as high-temperature gas-cooled reactors and gas-cooled fast reactors, TRISO-coated particle fuel is designed, because this fuel is very robust with no failures anticipated during irradiation and under accident conditions. | Li Bingsheng Du Yangyang Wang Zhiguang | 2015 | IMP & HIRFL Annual Report2015，，1： | 2 |
| 5 | Effects of mass layer imperfect bonding on the electrical impedance of a quartz crystal microbalance显示文摘We study electrically forced vibrations of a crystal plate of AT-cut quartz carrying a thin mass layer operating as a quartz crystal microbalance for mass sensing.The mass layer is imperfectly bonded to the crystal plate with their interface described by the so-called interface-slip model which allows a discontinuity of the tangential interface displacement.Mindlin’s equations for piezoelectric plates are used.An analytical solution is obtained.The electrical impedance is calculated.The effects of an elastic interface and a viscoelastic interface are examined. | CHEN YangYang WANG Ji DU JianKe YANG JiaShi | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，11： | 2 |
| 6 | Decoding Cortical Glial Cell Development显示文摘Mouse cortical radial glial cells(RGCs)are primary neural stem cells that give rise to cortical oligodendrocytes,astrocytes,and olfactory bulb(OB)GABAergic interneurons in late embryogenesis.There are fundamental gaps in understanding how these diverse cell subtypes are generated.Here,by combining single-cell RNA-Seq with intersectional lineage analyses,we show that beginning at around E16.5,neocortical RGCs start to generate ASCL1^(+)EGFR^(+)apical multipotent intermediate progenitors(MIPCs),which then differentiate into basal MIPCs that express ASCL1,EGFR,OLIG2,and MKI67.These basal MIPCs undergo several rounds of divisions to generate most of the cortical oligodendrocytes and astrocytes and a subpopulation of OB interneurons.Finally,single-cell ATAC-Seq supported our model for the genetic logic underlying the specification and differentiation of cortical glial cells and OB interneurons.Taken together,this work reveals the process of cortical radial glial cell lineage progression and the developmental origins of cortical astrocytes and oligodendrocytes. | Xiaosu Li Guoping Liu Lin Yang Zhenmeiyu Li Zhuangzhi Zhang Zhejun Xu Yuqun Cai Heng Du Zihao Su Ziwu Wang Yangyang Duan Haotian Chen Zicong Shang Yan You Qi Zhang Miao He Bin Chen Zhengang Yang | 2021 | Neuroscience Bulletin2021，37，4： | 2 |
| 7 | Reliability Evaluation of All-User Terminals in LEO Satellite Communication Network Based on Modular Reduction显示文摘LEO satellite communication network has a large number of satellites distributed in low orbits,which leads to multiple coverage of many areas on the ground.It is hard work to describe and evaluate the reliability of LEO satellite communication network.To solve this problem,the reliability of all-user terminals in LEO satellite communication network is defined,and the corresponding reliability evaluation method is proposed in the paper.Due to the large scale of the interstellar network,a modular reduction algorithm using the modular network instead of the original network for state decomposition is proposed in this paper.Case study shows that the calculation time of the proposed method is equivalent to 6.28%of the original state space decomposition algorithm.On this basis,the reliability of LEO satellite communication network is further analyzed.It is found that the reliability of LEO satellite network was more sensitive to the reliability of Inter-Satellite link and the satisfaction of global coverage in the early stage,and it is more sensitive to the reliability of the satellite in the later stage.The satellite-ground link has a relatively constant impact on of LEO satellite network. | Yangyang Du Sifeng Liu Zhigeng Fang Su Gao | 2022 | China Communications2022，19，2： | 1 |
| 8 | Electromechanical modeling of eye fatigue detecting using flexible piezoelectric sensors显示文摘Eye fatigue has attracted significant interest due to its potential harm to human daily activities. An ultrathin flexible piezoelectric sensor was currently designed and fabricated to detect eye fatigue by deforming together with the eyelid epidermis. Herein we develop a theoretical model to illustrate the correlation between the eyelid motion and the signals output by the piezoelectric sensor. The theoretical predictions on the eyelid motion based on the measured electrical output agree well with the in vivo observations in experiment. A simple scaling law is established to evaluate the impacts of different parameters on the function ability of the flexible piezoelectric sensor. The results may provide useful guidelines for designing and optimizing similar devices for alike biological motions. | Chaofeng LU Shuang WU Yangyang ZHANG Yangkun DU | 2018 | Science China(Information Sciences)2018，61，6： | 1 |
| 9 | Studies on the roles of vanadyl sulfate and sodium nitrite in catalytic oxidation of benzyl alcohol with molecular oxygen显示文摘An efficient catalytic system consisting of vanadyl sulfate/sodium nitrite was disclosed previously for the oxidation of benzylic alcohols into aldehydes with molecular oxygen.However,the roles of catalyst components were not investigated.In this paper,we examined catalytic oxidation of benzyl alcohol as a model reaction,especially by infrared spectroscopy.The role of each component is discussed including nitrite,vanadyl,sulphate,and water.Sodium nitrite could be converted into nitrate and nitric acid.The vanadium(IV)could be smoothly oxidized into vanadium(V)under mild and acidic conditions without any organic ligands.The transformation of sulfate and bisulfate,the cessation of an induction period,and the oxidation of benzyl alcohol were closely interrelated.The multiple roles of water are discussed,including reduction of the induction period,participation in redox cycles of nitric compounds,deactivation of vanadium,and as a byproduct of oxidation.This study contributes to further development of aerobic oxidation using vanadium based catalysts. | Zhongtian Du Junxia Liu Tianliang Lu Yangyang Ma Jie Xu | 2015 | Science China Chemistry2015，58，1： | 1 |
| 10 | Recent advances in carbon-supported non-precious metal singleatom catalysts for energy conversion electrocatalysis显示文摘Non-precious metal single-atom catalysts(NPM-SACs)with unique electronic structures and coordination environments have gained much attention in electrocatalysis owing to their low cost,high atomic utilization,and high performance.NPM-SACs on carbon support(NPM-SACs/CS)are promising because of the carbon substrate with a large surface area,excellent electrical conductivity,and high chemical stability.This review provides an overview of recent developments in NPM-SACs/CS for the electrocatalytic field.First,the state-of-the-art synthesis methods and advanced characterization techniques of NPM-SACs/CS are discussed in detail.Then,the structural adjustment strategy of NPM-SACs/CS for optimizing electrocatalytic performance is introduced concisely.Furthermore,we provide a comprehensive summary of recent advances in developing NPM-SACs/CS for important electrochemical reactions,including carbon dioxide reduction reaction,hydrogen evolution reaction,oxygen evolution reaction,oxygen reduction reaction,and nitrogen reduction reaction.In the end,the existing challenges and future opportunities of NPM-SACs/CS in the electrocatalytic field are highlighted. | Li-Xia Liu Yangyang Ding Linan Zhu Jin-Cheng Li Huitong Du Xiang Li Zhaoyuan Lyu Dan Du Fuqiang Liu Yuanyuan Wang Wenlei Zhu Yuehe Lin | 2023 | National Science Open2023，2，2： | 1 |
| 11 | AI in spotting high-risk characteristics of medical imaging and molecular pathology显示文摘Medical imaging provides a comprehensive perspective and rich information for disease diagnosis.Combined with artificial intelligence technology,medical imaging can be further mined for detailed pathological information.Many studies have shown that the macroscopic imaging characteristics of tumors are closely related to microscopic gene,protein and molecular changes.In order to explore the function of artificial intelligence algorithms in in-depth analysis of medical imaging information,this paper reviews the articles published in recent years from three perspectives:medical imaging analysis method,clinical applications and the development of medical imaging in the direction of pathologicalmolecular prediction.We believe that AI-aidedmedical imaging analysis will be extensively contributing to precise and efficient clinical decision. | Chong Zhang Jionghui Gu Yangyang Zhu Zheling Meng Tong Tong Dongyang Li Zhenyu Liu Yang Du Kun Wang Jie Tian | 2021 | Precision Clinical Medicine2021，4，4： | 1 |
| 12 | Simple self-assembly of 3D laminated CuO/SnO2 hybrid for the detection of triethylamine显示文摘Tin dioxide is important gas sensor material and has wide applications in the detection of toxic gases and volatile organic compounds.Here,we synthesized a 3D laminated structural CuO/SnO2 material possessing p-n heterostructures.The morphology and structure were characterized by XRD,SEM,TEM and XPS techniques and the sensing properties were investigated for the detection of triethylamine(TEA).The results indicate that 3D laminated CuO/SnO2 material,assembled by lamellae consisting of ordered nanoparticles,exhibit an enhanced sensing performance compared with SnO2,and notably,CuO/SnO2 with size less than 1μm has obvious high selectivity in the detection of 100 ppm TEA.Particularly,it has a high response and stability to 1 and 5 ppm TEA(S is 8 and 33),and that is higher than SnO2 material,suggesting 3D laminated CuO/SnO2 is an effective ca ndidate material served as sensor platform to detect low-concentration amines. | Yangyang Shang Wenqiong Shi Ruihua Zhao Md.Maruf Ahmed Jinping Li Jianping Du | 2020 | Chinese Chemical Letters2020，31，8： | 1 |
| 13 | BLM helicase inhibition synergizes with PARP inhibition to improve the radiosensitivity of olaparib resistant non-small cell lung cancer cells by inhibiting homologous recombination repair显示文摘Objective:We aimed to investigate the radiosensitizing efficacy of the poly-ADP-ribose polymerase(PARP)inhibitor,olaparib,and the Bloom syndrome protein(BLM)helicase inhibitor,ML216,in non-small cell lung cancer(NSCLC)cells.Methods:Radiosensitization of NSCLC cells was assessed by colony formation and tumor growth assays.Mechanistically,the effects of ML216,olaparib,and radiation on cell and tumor proliferation,DNA damage,cell cycle,apoptosis,homologous recombination(HR)repair,and non-homologous end joining(NHEJ)repair activity were determined.Results:Both olaparib and ML216 enhanced the radiosensitivities of olaparib-sensitive H460 and H1299 cells,which was seen as decreased surviving fractions and Rad51 foci,increased total DNA damage,andγH2AX and 53BP1 foci(P<0.05).The expressions of HR repair proteins were remarkably decreased in olaparib-treated H460 and H1299 cells after irradiation(P<0.05),while olaparib combined with ML216 exerted a synergistic radiosensitization effect on olaparib-resistant A549 cells.In addition to increases of double strand break(DSB)damage and decreases of Rad51 foci,olaparib combined with ML216 also increased pDNA-PKcs(S2056)foci,abrogated G2 cell cycle arrest,and induced apoptosis in A549 lung cancer after irradiation in vitro and in vivo(P<0.05).Moreover,Western blot showed that olaparib combined with ML216 and irradiation inhibited HR repair,promoted NHEJ repair,and inactivated cell cycle checkpoint signals both in vitro and in vivo(P<0.05).Conclusions:Taken together,these results showed the efficacy of PARP and BLM helicase inhibitors for radiosensitizing NSCLC cells,and supported the model that BLM inhibition sensitizes cells to PARP inhibitor-mediated radiosensitization,as well as providing the basis for the potential clinical development of this combination for tumors intrinsically resistant to PARP inhibitors and radiotherapy. | Yangyang Kong Chang Xu Xiaohui Sun Hao Sun Xiaotong Zhao Ningning He Kaihua Ji Qin Wang Liqing Du Jinhan Wang Manman Zhang Yang Liu Yan Wang Qiang Liu | 2022 | Cancer Biology & Medicine2022，19，8： | 1 |
| 14 | Ultrasound-visualized nanocarriers with siRNA for targeted inhibition of M2-like TAM polarization to enhance photothermal therapy in NSCLC显示文摘Photothermal therapy(PTT)has received a lot of attention as a promising strategy for eliminating tumors quickly.However,the unavoidable inflammatory response during the treatment might result in a high concentration of M2-like tumor-associated macrophages(TAMs),increasing the risk of tumor recurrence and metastasis.To address this problem,gold-based nanocarriers(PGMP-small interfering RNA(siRNA)nanoparticles(NPs))containing STAT6siRNA,that inhibited M2-like TAM polarization,were designed and investigated for PTT and gene therapy of non-small cell lung cancer(NSCLC).In an NSCLC model,the nanocarriers demonstrated excellent siRNA delivery ability and a high gene transfection rate of up to 90%in macrophages,thus inhibiting the polarization of about 87%of M2-like TAMs and effectively suppressing the invasion and metastasis of NSCLC.Meanwhile,the unique gold nanosphere structure offered improved PTT and contrast-enhanced ultrasound imaging,thus contributing to the efficient elimination and real-time monitoring of the tumor tissues.These nanocarriers with combined gene and photothermal therapeutic capabilities improved the efficacy of single-modality treatment,and showed the potential to inhibit cancer cell recurrence and metastasis to ultimately cure NSCLC. | Wenhao Lv Chen Xu Hao Wu Yangyang Zhu Ozioma Udochukwu Akakuru Hui Du Fang Nie Aiguo Wu Juan Li | 2023 | Nano Research2023，16，1： | 0 |
| 15 | Experimental Characterization and Model Verification of Thermal Conductivity from Mesoporous to Macroporous SiOC Ceramics显示文摘Based on the chemical cross-linking method,this paper uses polydimethylsiloxane with various viscosities of 10 cSt,20 cSt,50 cSt,and 100 cSt to synthesize mesoporous and macroporous SiOC ceramics.Their thermal conductivities are measured by using 3ωmethod with high accuracy.Three typical models for their thermal conductivities,i.e.,series model(SM),maxwell-Eucken 1 model(ME1),and effective medium theory(EMT)model,are utilized to derive the empirical formula through the multi-parameter linear optimization algorithm,which agrees well with the experimental results.The effects of pore size and specific surface area on the overall thermal conductivity of the porous structure are explored.Interestingly,it is found that the thermal conductivities of both gas phase and solid phase inside the porous structure increase with the increasing pore size at the nanometer scale,but the overall thermal conductivity of the porous structure decreases with the increasing pore size.Scanning electron microscopy graphs corroborate that the extension of the heat transfer route and the barrier of more pores between the solid phases together cause the reduction of the gas-solid coupling thermal conductivity of SiOC ceramics with larger pore size.On the contrary,the miniaturization of individual particles through modulating the synthesis parameters can increase the number of small pores in the sample itself to meet the pseudo-lattice vibration conditions,which results in the increment of the gas-solid coupling thermal conductivity and the overall thermal conductivity of the porous structure.These findings would provide meaningful guidance for designing SiOC porous ceramic super-insulation materials with extremely low thermal conductivity. | QIU Lin DU Yanbo BAI Yangyang FENG Yanhui ZHANG Xinxin WU Jin WANG Xiaotian XU Caihong | 2021 | Journal of Thermal Science2021，30，2： | 0 |
| 16 | Moving Towards Refinement:Rural Organizations and Rural Governance in the Song Dynasty显示文摘With the society moving from decentralization to a whole and the strengthening of centralization,the state gradually enhanced the involvement in rural community.At the same time,the management of people-land relationship tended to be refined.The original Xiang-Li system,which was suitable to decentralized community,was no longer needed by the state,and would be inevitably replaced by smaller rural organizations that were suitable to centralized community.In this context,the Du-Bao system emerged as the times required.During this process,the combination of the Bao-Jia system,territory division,and mapping technique played a key role in pushing forward the refinement management of people-land relationship.From the Xiang-Li system to the Du-Bao system,from rural officials to rural servants,when rural power was transferred to the government,more new rural authority systems that embodied the state will replaced the traditional rural authority system.There was a lack of obvious dominant class such as aristocratic families and gentry representatives in rural community in the Song Dynasty.Such a unique era provided an excellent opportunity for the state forces to go deep into and change rural community.For this reason,the state authority upon rural areas in the Song Dynasty exceeded the Han and Tang dynasties,and even the subsequent Yuan,Ming,and Qingdynasties. | Liao Yin Du Yangyang | 2023 | Frontiers of History in China-Selected Publications from Chinese Universities2023，18，4： | 0 |
| 17 | MOF-derived Zn-Co-Ni sulfides with hollow nanosword arrays for high-efficiency overall water and urea electrolysis显示文摘Water electrolysis is a promising technology to produce hydrogen but it was severely restricted by the slow oxygen evolution reaction(OER).Herein,we firstly reported an advanced electrocatalyst of MOF-derived hollow Zn-Co-Ni sulfides(ZnS@Co_(9)S_(8)@Ni_(3)S_(2)-1/2,abbreviated as ZCNS-1/2)nanosword arrays(NSAs)with remarkable hydrogen evolution reaction(HER),OER and corresponding water electrolysis performance.To reach a current density of 10 mA cm^(-2),the cell voltage of assembled ZCNS-1/2//ZCNS-1/2 for urea electrolysis(1.314 V)is 208 mV lower than that for water electrolysis(1.522 V)and stably catalyzed for over 15 h,substantially outperforming the most reported water and urea electrolysis electrocatalysts.Density functional theory calculations and experimental result clearly reveal that the properties of large electrochemical active surface area(ECSA)caused by hollow NSAs and fast charge transfer resulted from the Co_(9)S_(8)@Ni_(3)S_(2) heterostructure endow the ZCNS-1/2 electrode with an enhanced electrocatalytic performance. | Xiaoqiang Du Yangyang Ding Xiaoshuang Zhang | 2023 | Green Energy & Environment2023，8，3： | 0 |
| 18 | 3-5 An Experiment Setup for Synergetic Effect of Irradiation and LBE in IMP显示文摘Due to its unique properties, such as favorable neutronic characteristic, low melting point(~125 ?C) and highboiling point (> 1 600 ?C), good natural circulation and chemical inertness with water and air (unlike sodium), etc,lead bismuth eutectic (LBE) has been considered as perspective coolant and spallation target for accelerator drivensystems (ADS)[1;2]. The spallation structural materials of ADS will be long-term irradiated with fast neutrons whilesimultaneous being contact with LBE coolant. In the past few decades, irradiation or LBE corrosion behaviors invarious of materials have been massively investigated for the purpose of developing ADS. However, there are onlya few experiment data on the combined effect of irradiation and LBE corrosion on structural materials due to lackof related experimental setups[3;4]. Such tests are not only essential for ensuring the safety and reliability of ADS,but also necessary for building a database for licensing any materials for use in LBE cooled nuclear systems. | Yao Cunfeng Wang Zhiguang Zhang Hongpeng Sheng Yanbin Chang Hailong Sun Jianrong Wei Kongfang Li Bingsheng Shen Tielong Pang Lilong Zhu Yabin Wang Dong Du Yangyang Wang Ji Cui Minhuan Zhu Huiping Liu Chao Yang Yongwei Fan Deliang | 2014 | IMP & HIRFL Annual Report2014，，1： | 0 |
| 19 | 3-11 Transmission Electron Microscopy Investigations of Bubble Formation along GBs in He-implanted Polycrystalline SiC显示文摘Because of the low cross-section for neutron capture and its excellent structural, chemical and mechanicalstability, silicon carbide (SiC) is an important material with application in the development of nuclear energyand waste technologies. The (n,) nuclear reaction inevitably introduces numerous He in SiC. Because of the lowsolubility of He atoms in SiC, a certain concentration of He atoms that are trapped in the matrix in the formof helium-vacancy clusters would form bubbles upon annealing. He bubbles would perhaps lead to degradation ofmaterial properties. Especially, He bubbles along Grain boundaries (GBs) can cause embrittlement by intergranularfracture, as usually observed in metals. Therefore, it is important to investigate the nucleation and growth of Hebubbles along GBs in He-implanted SiC. | Li Bingsheng Wang Zhiguang Du Yangyang Wei Kongfang Yao Cunfeng Sun Jianrong Zhang Hongpeng | 2014 | IMP & HIRFL Annual Report2014，，1： | 0 |
| 20 | 3-12 Recrystallization of He-ion Implanted 6H-SiC upon Annealing显示文摘SiC is a wide band-gap semiconductor material with high breakdown voltage, large electron saturation migrationrate, small dielectric coefficient and good chemical stability which is of great interest for high-speed communicationand high-power control devices. For SiC microelectronics devices, ion-implantation is a kind of great ways to dopeimpurities. However, high dose energetic ions could create radiation damages which may cause amorphization atRT. Thermally annealing could cause recrystallization of SiC amorphous layers which significantly affects electricand optical properties of SiC material. Recrystallization of amorphous SiC occurs in a wide window of annealingtemperature. A partial recrystallization of amorphous SiC occurs upon annealing at a low temperature, whereascomplete recrystallization of amorphous SiC occurs upon annealing at a high temperature. He implantation-induceddamage in SiC has been extensively investigated. However, the complete recrystallization threshold temperature ofkeV He-ion implantation has not been systematically studied. | Li Bingsheng Du Yangyang Wang Zhiguang | 2014 | IMP & HIRFL Annual Report2014，，1： | 0 |
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