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1649篇 您的检索式:作者名="Dowding"
    题名 作者 年代 出处 被引量
1Carbon sequestration potential of the Habanero reservoir when carbon dioxide is used as the heat exchange fluid显示文摘The use of sequestered carbon dioxide(CO_2) as the heat exchange fluid in enhanced geothermal system(EGS) has significant potential to increase their productivity, contribute further to reducing carbon emissions and increase the economic viability of geothermal power generation. Coupled CO_2 sequestration and geothermal energy production from hot dry rock(HDR) EGS were first proposed 15 years ago but have yet to be practically implemented. This paper reviews some of the issues in assessing these systems with particular focus on the power generation and CO_2 sequestration capacity. The Habanero geothermal field in the Cooper Basin of South Australia is assessed for its potential CO_2 storage capacity if supercritical CO_2 is used as the working fluid for heat extraction. The analysis suggests that the major CO_2 sequestration mechanisms are the storage in the fracture-stimulation damaged zone followed by diffusion into the pores within the rock matrix. The assessment indicates that 5% of working fluid loss commonly suggested as the storage capacity might be an over-estimate of the long-term CO_2 sequestration capacity of EGS in which supercritical CO_2 is used as the circulation fluid.Chaoshui Xu Peter Dowd Qi Li 2016Journal of Rock Mechanics and Geotechnical Engineering2016,8,1:4
2Can bacterial virulence factors predict antibiotic resistant Helicobacter pylori infection?显示文摘AIM To evaluate the association between virulence factor status and antibiotic resistance in Helicobacter pylori(H. pylori)-infected patients in Ireland. METHODS DNA was extracted from antral and corpus biopsies obtained from 165 H. pylori-infected patients. Genotyping for clarithromycin and fluoroquinolone-mediating mutations was performed using the Genotype Helico DR assay. cag A and vac A genotypes were investigated using PCR. RESULTS Primary, secondary and overall resistance rates for clarithromycin were 50.5%(n = 53/105), 78.3%(n = 47/60) and 60.6%(n = 100/165), respectively. Primary, secondary and overall resistance rates for fluoroquinolones were 15.2%(n = 16/105) and 28.3%(n = 17/60) and 20%(n = 33/165), respectively. Resistance to both antibiotics was 12.4%(n = 13/105) in treatment-na?ve patients, 25%(n = 15/60) in those previously treated and 17%(n = 28/165) overall. A cag A-positive genotype was detected in 22.4%(n = 37/165) of patient samples. The dominant vac A genotype was S1/M2 at 44.8%(n = 74/165), followed by S2/M2 at 26.7%(n = 44/165), S1/M1 at 23.6%(n = 39/165) and S2/M1 at 4.8%(n = 8/165). Primary clarithromycin resistance was significantly lower in cag A-positive strains than in cag A-negative strains [32%(n = 8/25) vs 56.3%(n = 45/80); P = 0.03]. Similarly, in patients infected with more virulent H. pylori strains bearing the vac A s1 genotype, primary clarithromycin resistance was significantly lower than in those infected with less virulent strains bearing the vac A s2 genotype, [41%(n = 32/78) vs 77.8%(n = 21/27); P = 0.0001]. No statistically significant association was found between primary fluoroquinolone resistance and virulence factor status.CONCLUSION Genotypic H. pylori clarithromycin resistance is high and cag A-negative strains are dominant in our population. Less virulent(cag A-negative and vac A S2-containing) strains of H. pylori are associated with primary clarithromycin resistance.Denise E Brennan Colin Dowd Colm O'Morain Deirdre McNamara Sinéad M Smith 2018World Journal of Gastroenterology2018,24,9:4
3Central CB2 receptors in inflammation-driven neurodegeneration: dysregulation and therapeutic potential显示文摘In recent times there has been an intensification of interest in the pathological role of neuroinflammation in neurodegenerative disease.Neuroprotective strategies to slow,halt or reverse neurodegeneration have not proven fruitful clinically,and the notion of a multi-hit hypothesis in the progression of neurodegenerative disease has steered focus towards other contributoryRuth M. Concannon Eilis Dowd 2016Neural Regeneration Research2016,11,9:4
4Principles of time domain reflectometry applied to measurement of rock mass deformation显示文摘Dowding C H Su M B O'Connor K 1988International Journal of Rock Mechanics Mining Sciences & Geomechanics Abstracts1988,25,5:2
5Measurement of rock mass deformation with grouted coaxial antenna cables显示文摘Dowding C H Su M B O'Connor K 1989Rock Mechanics and Rock Engineering1989,22,1:2
6Partial growth-hormone insensitivity: The role of growth-hormone receptor mutations in idiopathic short stature显示文摘Audrey D. Goddard Patrick Dowd Steven Chernausek Mitchell Geffner Joseph Gertner Raymond Hintz Nancy Hopwood Selna Kaplan Leslie Plotnick Alan Rogol Robert Rosenfield Paul Saenger Nellie Mauras Richard Hershkopf Morris Angulo Kenneth Attie 1997The Journal of Pediatrics1997,,1:2
7Preparation and Swelling Properties of Poly ( NIPAM ) Minigel Particles Prepared by Inverse Suspension Polymerization 显示文摘Dowding P J Vincent B Williams E 2000J Colloid and Interface Sei2000,221,26:1
8Association of central obesity with early Carotid intima-media thickening is independent of that from other risk factors显示文摘Maher V O'Dowd M Carey M 2009Int J Obes ( Lond)2009,33,1:1
9Swine flu claims first European death,as cases worldwide rise to 36,000显示文摘O'Dowd A 2009BMJ2009,338,:1
10Pricing death: Frameworks for the valuation and securitization of mortality risk 显示文摘Cairns A J G Blake D Dowd K 2006ASTIN Bulletin2006,36,1:1
11Complete genomes of two clinical Staphylococcus aureus strains:evidence for the rapid evolution of virulence and drug resistance显示文摘Holden MT Feil EJ Lindsay JA Peacock SJ Day NP Enright MC Foster TJ Moore CE Hurst L Atkin R Barron A Bason N Bentley SD Chillingworth C Chillingworth T Churcher C Clark L Corton C Cronin A Doggett J Dowd L Feltwell T Hance Z Harris B Hauser H Holroyd S Jagels K James KD Lennard N Line A Mayes R Moule S Mungall K Ormond D Quail MA Rabbinowitsch E Rutherford K Sanders M Sharp S Simmonds M Stevens K Whitehead S Barrell BG Spratt BG Parkhill J 2004Proc Natl Acad Sci USA2004,101,26:1
12Currency competition, network externalities and switching costs: towards an alternative view of optimum currency areas显示文摘Dowd Kevin and Greenaway David 1993The Economic Journal1993,103,420:1
13Retinoid X receptorsstimulate and 9-cis retinoic acid inhibits 1,25-dihydroxyvitaminD3-activated expression of the rat osteocalcin gene显示文摘Macdonald PN Dowd DR Nakajima S 1993Mol CellBiol1993,13,9:1
14Cryptic vascular malformation of the spinal cord:diagnostic by magnetic resonance and outcome of surgery显示文摘Barnwell SL Dowd CF Davis RL 1990J Neurosurg1990,72,3:1
15ANGⅡ stimulates endothelial nitric oxide synthase expression in bovine pulmonary artery endothelium显示文摘Olson SC Dowds TA Pino PA 1997Am J Physiol1997,273,21:1
16Rapid stimulation of EAAC1-mediated Na+-dependent L-glutamate transport activity in C6 glioma cells by phorbol ester显示文摘Dowd LA Robinson MB 1996J Neurochem1996,67,:1
17Unravelling the roles of the Apelin system:prospective therapeutic applications in heart failure and obesity 显示文摘Lee DK Gorge SR O'Dowd BF 2006Trends Pharmacol Sci2006,27,4:1
18Future CH4 emissions from rice production显示文摘Anastasi C Dowding M Simpson V J 1992Journal of Geophysical Research1992,97,:1
19An assessment of the effect of pulsed electrical fields on tenderness and selected quality attributes of post rigour beef muscle显示文摘O'Dowd L P Arimi J M Noci F Cronin D A Lyng J G 2013Meat Sicence2013,93,2:1
20A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11 显示文摘O'Dowd BF Heiber M Chan A 1993Gene1993,136,12:1
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