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| 1 | Metabolomic studies of human gastric cancer:Review显示文摘Metabolomics is a field of study in systems biology that involves the identification and quantification of metabolites present in a biological system. Analyzing metabolic differences between unperturbed and perturbed networks, such as cancerous and noncancerous samples, can provide insight into underlying disease pathology, disease prognosis and diagnosis. Despite the large number of review articles concerning metabolomics and its application in cancer research, biomarker and drug discovery, these reviews do not focus on a specific type of cancer. Metabolomics may provide biomarkers useful for identification of early stage gastric cancer, potentially addressing an important clinical need. Here, we present a short review on metabolomics as a tool for biomarker discovery in human gastric cancer, with a primary focus on its use as a predictor of anticancer drug chemosensitivity, diagnosis, prognosis, and metastasis. | Naresh Doni Jayavelu Nadav S Bar | 2014 | World Journal of Gastroenterology2014，20，25： | 19 |
| 2 | Tensile and fracture properties of an Mg-RE-Zn alloy at elevated temperatures显示文摘Magnesium alloy EZ10(Mg-RE-Zn) was deformed in tension at temperatures from 20 up to 520 °C. A rapid decrease of the yield and tensile strength with temperature was observed at temperatures higher than 300 °C. On the other hand, ductility of samples rapidly increased in the same temperature range. Light microscopy and scanning electron microscopy was used to reveal the reason for these behaviours. Intermetallic particles in grain boundaries are responsible for excellent mechanical properties at lower temperatures. Diffusional processes occurring at temperatures higher than 300 °C significantly influenced the deformation mechanism as well as the fracture character. | TROJANOVZuzanka DONI Tibor LUK Pavel PALEK Peter CHALUPOV Mária TILLOV Eva BASTOVANSKY Ronald | 2014 | Journal of Rare Earths2014，32，6： | 3 |
| 3 | 等温微量量热法研究石油污染对土壤微生物活性的影响显示文摘利用TAMⅢ等温微量量热仪研究不同浓度的石油污染对土壤微生物活性的影响。对大港油田不同石油污染程度的土壤样品(3683-5-1、西51-5、西15-14和8-13-6H-1)以及实验室配置的短时间内石油污染土壤(空白、0.5%、1.5%、2.5%和4.0%)进行了微量热检测。含油量升高,总放热量升高,生长速率常数降低,峰值功率先升高后降低,达到最大峰值功率的时间随着含油量的升高而延长。结果表明,石油污染会影响土壤微生物的活性,并且在低浓度时促进微生物的生长,石油浓度高时会抑制土壤中微生物的生长代谢。 | 佘文文 姚俊 王飞 蔡珉敏 王静伟 宋长顺 Brunello Ceccanti Serena Doni | 2013 | 环境工程学报2013，7，9： | 2 |
| 4 | Antioxidant treatment attenuates hyperglycemia-induced cardiomyocyte death in rats显示文摘 | Fabio Fiordaliso Roberto Bianchi Lidia Staszewsky Ivan Cuccovillo Mirko Doni Teresa Laragione Monica Salio Costanza Savino Silvia Melucci Francesco Santangelo Eugenio Scanziani Serge Masson Pietro Ghezzi Roberto Latini | 2004 | Journal of Molecular and Cellular Cardiology2004，，5： | 2 |
| 5 | Optimizing the Double Inverted Pendulum′s Performance via the Uniform Neuro Multiobjective Genetic Algorithm显示文摘An inverted pendulum is a sensitive system of highly coupled parameters, in laboratories, it is popular for modelling nonlinear systems such as mechanisms and control systems, and also for optimizing programmes before those programmes are applied in real situations. This study aims to find the optimum input setting for a double inverted pendulum(DIP), which requires an appropriate input to be able to stand and to achieve robust stability even when the system model is unknown. Such a DIP input could be widely applied in engineering fields for optimizing unknown systems with a limited budget. Previous studies have used various mathematical approaches to optimize settings for DIP, then have designed control algorithms or physical mathematical models.This study did not adopt a mathematical approach for the DIP controller because our DIP has five input parameters within its nondeterministic system model. This paper proposes a novel algorithm, named Uni Neuro, that integrates neural networks(NNs) and a uniform design(UD) in a model formed by input and response to the experimental data(metamodel). We employed a hybrid UD multiobjective genetic algorithm(HUDMOGA) for obtaining the optimized setting input parameters. The UD was also embedded in the HUDMOGA for enriching the solution set, whereas each chromosome used for crossover, mutation, and generation of the UD was determined through a selection procedure and derived individually. Subsequently, we combined the Euclidean distance and Pareto front to improve the performance of the algorithm. Finally, DIP equipment was used to confirm the settings. The proposed algorithm can produce 9 alternative configured input parameter values to swing-up then standing in robust stability of the DIP from only 25 training data items and 20 optimized simulation results. In comparison to the full factorial design, this design can save considerable experiment time because the metamodel can be formed by only 25 experiments using the UD. Furthermore, the proposed algorithm can be applied to nonlinear systems with multiple constraints. | Dony Hidayat Al-Janan Hao-Chin Chang Yeh-Peng Chen Tung-Kuan Liu | 2017 | International Journal of Automation and computing2017，14，6： | 2 |
| 6 | Specific biotests to assess eco-toxicity of biodegradable polymer materials in soil显示文摘Eco-toxicity investigation of polymer materials was considered extremely necessary for their potential menace,which was widely use as mulching materials in agricultural.In this study,polyethylene(PE),polystyrene(PS)and synthetic biomaterials-Ecoflex and cellulose were applying into soil cultivated with two potential indicator plants species:oat(A v ena sati v a)and red radish(Raphanus sativum).Variety of chemical,biochemical parameters and enzyme activity in soil were proved as effective approach to evaluate polymers phytotoxicity in plant-soil mesocosm.The F-value of biomass,pH,heavy metal and electoral conductivity of Raphanus behaved significant different from T0.Significant analysis results indicated biodegradation was fast in PE than PS,besides,heavy metals were dramatically decrease in the end implied the plant absorption may help decrease heavy metal toxicity.The increase value at T2 of Dehydrogenase activity(0.84 higher than average value for Avena&0.91 higher for Raphanus),Metabolic Index(3.12 higher than average value for Avena&3.81 higher for Raphanus)means during soil enzyme activity was promoted by biodegradation for its heterotrophic organisms’energy transportation was stimulated.Statistics analysis was carried on Biplot PC1(24.2%of the total variance),PC2(23.2%of the total variance),versus PC3(22.8%of the total variance),which indicated phosphatase activity and metabolic index was significant correlated,and high correlation of ammonium and protease activity.Furthermore,the effects were more evident in Raphanus treatments than in Avena,suggesting the higher sensitivity of Raphanus to polymers treatment,which indicate biodegradation of polymers in Raphanus treatment has produced intermediate phytotoxic compounds. | Haiyan Chen Fei Wang Huilun Chen HongDa Fang Weiying Feng Yuan Wei FanFan Wang HaiLei Su YiDong Mi Min Zhou XinRu Li Serena Doni Andrea Corti | 2021 | Journal of Environmental Sciences2021，33，7： | 2 |
| 7 | Reversal of experimental pulmonary hypertension by PDGF inhibition显示文摘 | Schermuly R T Dony E Ghofrani H A | 2005 | J Clin Invest2005，115，10： | 1 |
| 8 | Production of the soluble pattern recognition receptor PTX-3 by myeloid but not plasmacytoid,dendritic cells显示文摘 | Doni A Peri G Chieppa M | 2003 | Eur J Immunol2003，33，10： | 1 |
| 9 | Recombinant polypeptide from the gp48 region of the bovine viral diarrhoea virus (BVDV) detects serum antibodies in vaccinated and infected cattle 显示文摘 | Kwang J Littledike E Donis R | 1992 | Vet Microbiol1992，32，： | 1 |
| 10 | The long pentraxin PTX3 as alink among innate immunity,inflammation,and female fertility显示文摘 | Bottazzi B Bastone A Doni A el al | 2006 | JLeukoc Biol2006，79，5： | 1 |
| 11 | Gemcitabine with or without continuous infusion 5-FU in advanced pancreatic cancer: a randomised phase Ⅱ trial of the italian pncology group for clinical research (GOIRC) 显示文摘 | Di Costanzo F Carlini P Doni L | 2005 | Br J Cancer2005，93，： | 1 |
| 12 | Pentraxins in innateimmunity:fromC-reactive protein to the long pentraxin PTX3显示文摘 | Mantovani Garlanda DonI | 2008 | Clinlmmunoi2008，28，1： | 1 |
| 13 | Neural network approaches to image compression 显示文摘 | Dony R D | 1995 | Proc IEEE1995，83，： | 1 |
| 14 | Circulating levels of the long pen-traxin 3 PTX3 correlate with severity of infection in cirtically ill pa-tients显示文摘 | Meller B Peri G Doni A | 2001 | Crit Care Med2001，29，7： | 1 |
| 15 | Clinical trial design aveding undue placebo treatment显示文摘 | Amery W Dony JA | 1975 | J Clin Pharmacol1975，15，： | 1 |
| 16 | The bubbling of inert gas into the tundish--a means to improve steel cleanliness 显示文摘 | Marique C Dony A Mahieu J P | 1990 | Iron and Steelmaker1990，17，9： | 1 |
| 17 | Wetland plants, micro-organisms and enzymatic activities interrelations in treating N polluted water显示文摘 | Michela Salvato Maurizio Borin Serena Doni Cristina Macci Brunello Ceccanti Sara Marinari Grazia Masciandaro | 2012 | Ecological Engineering2012，，： | 1 |
| 18 | Effects of petroleum contamination on soil microbial numbers, metabolic activity and urease activity显示文摘 | Huan Guo Jun Yao Minmin Cai Yiguang Qian Yue Guo Hans H. Richnow Ruth E. Blake Serena Doni Brunello Ceccanti | 2012 | Chemosphere2012，，11： | 1 |
| 19 | Structure and function of the long pentraxin PTX3 glycosidic moiety: fine-tuning of the interaction with Clq and complement activation显示文摘 | Inforzato A Peri G Doni A | 2006 | Biochemistry2006，45，11： | 1 |
| 20 | The Humoral Pattern Recognition Molecule PTX3 Is a Key Component of Innate Immunity against Urinary Tract Infection显示文摘 | Sébastien Jaillon Federica Moalli Bryndis Ragnarsdottir Eduardo Bonavita Manoj Puthia Federica Riva Elisa Barbati Manuela Nebuloni Lidija Cvetko Krajinovic Alemka Markotic Sonia Valentino Andrea Doni Silvia Tartari Giorgio Graziani Alessandro Montanelli Y | 2014 | Immunity2014，，4： | 1 |
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