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| 1 | New innovations in pavement materials and engineering:A review on pavement engineering research 2021显示文摘Sustainable and resilient pavement infrastructure is critical for current economic and environmental challenges.In the past 10 years,the pavement infrastructure strongly supports the rapid development of the global social economy.New theories,new methods,new technologies and new materials related to pavement engineering are emerging.Deterioration of pavement infrastructure is a typical multi-physics problem.Because of actual coupled behaviors of traffic and environmental conditions,predictions of pavement service life become more and more complicated and require a deep knowledge of pavement material analysis.In order to summarize the current and determine the future research of pavement engineering,Journal of Traffic and Transportation Engineering(English Edition)has launched a review paper on the topic of'New innovations in pavement materials and engineering:A review on pavement engineering research 2021'.Based on the joint-effort of 43 scholars from 24 well-known universities in highway engineering,this review paper systematically analyzes the research status and future development direction of 5 major fields of pavement engineering in the world.The content includes asphalt binder performance and modeling,mixture performance and modeling of pavement materials,multi-scale mechanics,green and sustainable pavement,and intelligent pavement.Overall,this review paper is able to provide references and insights for researchers and engineers in the field of pavement engineering. | JTTE Editorial Office Jiaqi Chen Hancheng Dan Yongjie Ding Yangming Gao Meng Guo Shuaicheng Guo Bingye Han Bin Hong Yue Hou Chichun Hu Jing Hu Ju Huyan Jiwang Jiang Wei Jiang Cheng Li Pengfei Liu Yu Liu Zhuangzhuang Liu Guoyang Lu Jian Ouyang Xin Qu Dongya Ren Chao Wang Chaohui Wang Dawei Wang Di Wang Hainian Wang Haopeng Wang Yue Xiao Chao Xing Huining Xu Yu Yan Xu Yang Lingyun You Zhanping You Bin Yu Huayang Yu Huanan Yu Henglong Zhang Jizhe Zhang Changhong Zhou Changjun Zhou Xingyi Zhu | 2021 | Journal of Traffic and Transportation Engineering(English Edition)2021，8，6： | 7 |
| 2 | Engineering Escherichia coli to improve tryptophan production via genetic manipulation of precursor and cofactor pathways显示文摘Optimizing the supply of biosynthetic precursors and cofactors is usually an effective metabolic strategy to improve the production of target compounds.Here,the combination of optimizing precursor synthesis and balancing cofactor metabolism was adopted to improve tryptophan production in Escherichia coli.First,glutamine synthesis was improved by expressing heterologous glutamine synthetase from Bacillus subtilis and Bacillus megaterium in the engineered Escherichia coli strain KW001,resulting in the best candidate strain TS-1.Then icd and gdhA were overexpressed in TS-1,which led to the accumulation of 1.060 g/L tryptophan.Subsequently,one more copy of prs was introduced on the chromosome to increase the flux of 5-phospho-α-D-ribose 1-diphosphate followed by the expression of mutated serA and thrA to increase the precursor supply of serine,resulting in the accumulation of 1.380 g/L tryptophan.Finally,to maintain cofactor balance,sthA and pntAB,encoding transhydrogenase,were overexpressed.With sufficient amounts of precursors and balanced cofactors,the engineered strain could produce 1.710 g/L tryptophan after 48 h of shake-flask fermentation,which was 2.76-times higher than the titer of the parent strain.Taken together,our results demonstrate that the combination of optimizing precursor supply and regulating cofactor metabolism is an effective approach for high-level production of tryptophan.Similar strategies could be applied to the production of other amino acids or related derivatives. | Zhu Li Dongqin Ding Huiying Wang Linxia Liu Huan Fang Tao Chen Dawei Zhang | 2020 | Synthetic and Systems Biotechnology2020，5，3： | 5 |
| 3 | Dynamic microwave-assisted extraction combined with liquid phase microextraction based on the solidification of a floating drop for the analysis of organochlorine pesticides in grains followed by GC显示文摘A convenient,cost-effective and fast method using dynamic microwave-assisted extraction and liquid phase microextraction based on the solidification of a floating drop was proposed to analyze organochlorine pesticides in grains including rice,maize and millet.Twelve samples can be processed simultaneously in the method.During the extraction process,10%acetonitrile-water solutions containing 110μL of n-hexadecane were used to extract organochlorine pesticides.Subsequently,1.0 g sodium chloride was placed in the extract,and then centrifuged and cooled.The n-hexadecane drops containing the analytes were solidifi ed and transferred for determination by gas chromatography-electron capture detector without any further filtration or cleaning process.Limits of detection for organochlorine pesticides were 0.97–1.01μg/kg and the RSDs were in the range of 2.6%–8.5%.The developed technology has succeeded in analyzing six real grains samples and the recoveries of the organochlorine pesticides were 72.2%–94.3%.Compared with the published extraction methods,the developed method was used to analyze organochlorine pesticides in grains,being more environmentally friendly,which is suitable for the daily determination of organochlorine pesticides. | Guijie Li Xu Zhang Tingting Liu Hongxiu Fan Hongcheng Liu Shangyu Li Dawei Wang Lan Ding | 2021 | Food Science and Human Wellness2021，10，3： | 4 |
| 4 | H-infinity filtering for discrete-time switched linear systems under arbitrary switching显示文摘This paper is concerned with the problem of H-infinity filtering for discrete-time switched linear systems under arbitrary switching laws.New sufficient conditions for the solvability of the problem are given via switched quadratic Lyapunov functions.Based on Finsler's lemma,two sets of slack variables with special structure are introduced to provide extra degrees of freedom in optimizing the guaranteed H-infinity performance.Compared to the existing methods,the proposed one has better performances and less conservatism.An example is given to illustrate its effectiveness. | Ding, Dawei Yang, Guanghong Li, Xiaoli | 2011 | 控制理论与应用(英文版)2011，9，2： | 4 |
| 5 | Characterization of the unprecedented polynya events north of Greenland in 2017/2018 using remote sensing and reanalysis data显示文摘Based on an ice concentration threshold of 90%,it has been identified that two polynya events occurred in the region north of Greenland during the 2017/2018 ice season.The winter event lasted from February 20 to March 3,2018 and the summer event persisted from August 2 to September 5,2018.The minimum ice concentration derived from Advanced Microwave Scanning Radiometer 2(AMSR2)observations was 72%and 65%during the winter and summer events,respectively.The occurrence of both events can be related to strengthened southerly winds associated with an increased east-west zonal surface level air pressure gradient across the north Greenland due to perturbation of mid-troposphere polar vortex.The relatively warm air temperature during the 2017/2018 freezing season in comparison with previous years,together with the occurrence of the winter polynya,formed favourable pre-conditions for ice field fracturing in summer,which promoted the formation of the summer polynya.Diminished southerly winds and increased cover of new ice over the open water were the dominant factors for the disappearance of the winter polynya,whereas increased ice inflow from the north was the primary factor behind the closure of the summer polynya.Sentinel-1 Synthetic Aperture Radar(SAR)images were found better suited than AMSR2 observations for quantification of a new ice product during the polynya event because the SAR images have high potential for mapping of different sea ice regimes with finely spatial resolution.The unprecedented polynya events north of Greenland in 2017/2018 are important from the perspective of Arctic sea ice loss because they occurred in a region that could potentially be the last“Arctic sea ice refuge”in future summers. | Ruibo Lei Dawei Gui Zhouli Yuan Xiaoping Pang Ding Tao Mengxi Zhai | 2020 | Acta Oceanologica Sinica2020，39，9： | 3 |
| 6 | In situ stress state and seismic hazard in the Dayi seismic gap of the Longmenshan thrust belt显示文摘In the Longmenshan thrust belt,the Dayi seismic gap,an area with few earthquakes,is located between the ruptures of the 2008 Wenchuan Earthquake and the 2013 Lushan Earthquake,with a length of approximately 40–60 km.To date,however,the extent of the seismic hazard of the Dayi seismic gap and whether this gap is under high stress are still hotly debated.To further evaluate the seismic hazard of the Dayi seismic gap with regard to stress,two boreholes(1,000 and 500 m deep)were arranged to carry out hydraulic fracturing in situ stress measurement on either side of the Shuangshi-Dachuan fault zone.This zone has a high seismic hazard and the capacity to undergo surface rupture.Through the analogy of this new data with stability analysis using Byerlee’s Law and existing stress measurement data collected before strong earthquakes,the results show that the area surrounding the Shuangshi-Dachuan fault zone in the Dayi seismic gap(Dachuan Town)is in a state of high in situ stress,and has the conditions necessary for friction slip,with the potential hazard of moderate to strong earthquakes.Our results are the first to reveal the in situ stress profile at a depth of 1,000 m in the Dayi seismic gap,and provide new data for comprehensive evaluation of the seismic hazard in this seismic gap,which is of great significance to explore the mechanism of earthquake occurrence and to help mitigate future disaster. | Bing LI Furen XIE Jinshui HUANG Xiwei XU Qiliang GUO Guangwei ZHANG Junshan XU Jianxin WANG Dawei JIANG Jian WANG Lifeng DING | 2022 | Science China Earth Sciences2022，65，7： | 3 |
| 7 | Mechanism,condition and characteristics for the formation of the network structure in Zr-Al-Ni-Cu bulk metallic glasses显示文摘Mechanism,condition and characteristics for the formation of the network structure in a group of Zr-Al-Ni-Cu bulk metallic glasses(BMGs) were investigated.The results show that the constituent segregation and/or the symplastic growth would be the mechanisms for the formation of the cell structure in the present Zr-Al-Ni-Cu BMGs.The cell structure can be easily obtained for the glass forming alloys whose compositions locate nearby the eutectic point.The shorter the distance is from the eutectic point,the larger the cell and the thicker the cell wall of the network structure will be.The present investigation would provide useful information for the development of the BMG with the network structure. | AN WeiKe DING DaWei CAI AnHui ZHOU GuoJun LUO Yun LI JiangHong PENG YongYi | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，6： | 2 |
| 8 | Alkaline phosphatase activity in ornithogenic soils in polar tundra显示文摘Phosphatase plays an important role in the microbial liberation of phosphorus in soil systems.In this study,alkaline phosphatase activity (APA) was investigated from tundra ornithogenic soil profiles in Antarctica and Arctic.The organic carbon (TOC),total nitrogen (TN),and phosphorus fractions and pH were also analyzed in these soils.The correlation between APA and soil chemical properties is discussed.In almost all the soil profiles,APA showed the same variation patterns.The maximum APA appeared in the surface layers,and decreased with soil depth.The APA ranged from 1.00 ppm to 1 403.5 ppm with an average of approximately 408.3 ppm.The APA showed a significant positive correlation with TOC (r =0.70,p <0.001),TN (r =0.43,p =0.002),total phosphorus (r =0.39,p <0.05)and inorganic phosphorus (r =0.40,p =0.037),indicating that they were predominant factors affecting APA in the polar tundra soils.In addition,APA showed a significant negative correlation with Cu and Zn concentrations in the soils,indicating that Cu and Zn may inhibit APA.Our results showed that APA could be used as an important indicator for soil fertility in polar tundra ecosystems. | MA DaWei ZHU RenBin DING Wei SUN JianJun LIU YaShu SUN LiGuang | 2011 | Advances in Polar Science2011，22，2： | 2 |
| 9 | Positioning taxonomic research for the future显示文摘Why do taxonomists matter? The work of taxonomists is often understated if not completely misunderstood. Without taxonomists, organisms cannot be accurately identified, neither can these organisms be given universally accepted names, and reliably positioned in the phylogenetic tree of life. Thanks to the work of taxonomists over the last 269 years since Carl Linnaeus established the binomial system, we can now measure the health and wealth of our biodiversity in a refined, science-based inventory prescribed by stringent nomenclatural rules. | Deyuan Hong Wenying Zhuang Min Zhu Keping Ma Xiaoquan Wang Dawei Huang Yalin Zhang Guodong Ren Wenjun Bu Wanzhi Cai Dong Ren Ding Yang Aiping Liang Fengyan Bai Runzhi Zhang Fumin Lei Shuqiang Li Hongzhi Kong Lei Cai Yucheng Dai Chaodong Zhu Qisen Yang Jun Chen Zhongli Sha Jianping Jiang Jing Che Donghui Wu Jiatang Li Qiang Wang Xinli Wei Ming Bai Xingyue Liu Xuexin Chen Gexia Qiao | 2022 | Zoological Systematics2022，47，3： | 2 |
| 10 | Premonitory phenomenon of El Nino event reflected in the observations of LOD and sea level显示文摘Data sets of the changes of the length of day, the sea surface temperature in the eastern Pacific and of the sea level in Hong Long from tide gauge observations are used to analyze and reveal the reflections in the observations of the length of day and the sea level changes concerned with the premonitory phenomenon of next El Nino event. The results from this study indicate that a new El Nino event has been brewing with the ending of the strong La Nina event that started in early summer of 1998. The estimated formation period of the new El Nino event will begin before the end of 2000, and the peak period may be reached at around the end of 2001. | ZHENG Dawei DING Xiaoli ZHOU Yonghong CHEN Yongqi LI Zhilin LIAO Xinhao | 2000 | Chinese Science Bulletin2000，45，24： | 2 |
| 11 | Application of fluorescence in situ hybridization in the detection of bladder transitional-cell carcinoma: A multi-center clinical study based on Chinese population显示文摘Objective:To evaluate the diagnostic value of fluorescence in situ hybridization(FISH)in bladder cancer.Methods:We enrolled healthy volunteers and patients who were clinically suspected to have bladder cancer and conducted FISH tests and cytology examinations from August 2007 to December 2008.Receiver operating characteristic(ROC)curve analysis was performed and the area under curve(AUC)values were calculated for both the FISH and urine cytology tests.Results:A cohort of 988 healthy volunteers was enrolled to establish a reference range for the normal population.A total of 4807 patients with hematuria were prospectively,randomly enrolled for the simultaneous analysis of urine cytology,FISH testing,and a final diagnosis as determined by the pathologic findings of a biopsy or a surgically-excised specimen.Overall,the sensitivity of FISH in detecting transitional-cell carcinoma was 82.7%,while that of cytology was 33.4%(p<0.001).The sensitivity values of FISH for non-muscle invasive and muscle invasive bladder transitional-cell carcinoma were 81.7%and 89.6%,respectively(p=0.004).The sensitivity values of FISH for low and high grade bladder cancer were 82.6%and 90.1%,respectively(p=0.002).Conclusion:FISH is significantly more sensitive than voided urine cytology for detecting bladder cancer in patients evaluated for gross hematuria at all cancer grades and stages.Higher sensitivity using FISH was obtained in high grade and muscle invasive tumors. | Liqun Zhou Kaiwei Yang Xuesong Li Yi Ding Dawei Mu Hanzhong Li Yong Yan Jinyi Li Dongwen Wang Wei Li Yulong Cong Jiangping Gao Kewei Ma Yajun Xiao Sheng Zhang Hongyi Jiang Weilie Hu Qiang Wei Xunbo Jin Zhichen Guan Qingyong Liu Danfeng Xu Xin Gao Yongguang Jiang Weimin Gan Guang Sun Qing Wang Yanhui Liu Jianquan Hou Liping Xie Xishuang Song Fengshuo Jin Jiafu Feng Ming Cai Zhaozhao Liang Jie Zhang Dingwei Ye Lin Qi Lulin Ma Jianzhong Shou Yuping Dai Jianyong Shao Ye Tian Shizhe Hong Tao Xu Chuize Kong Zefeng Kang Yuexin Liu Xun Qu Benkang Shi Shaobin Zheng Yi Lin Shujie Xia Dong Wei Jianbo Wu Weiling Fu Zhiping Wang Jianbo Liang | 2019 | Asian Journal of Urology2019，6，1： | 2 |
| 12 | Development and validation of a UPLC–MS/MS assay for the determination of gemcitabine and its L-carnitine ester derivative in rat plasma and its application in oral pharmacokinetics显示文摘A simple and rapid UPLC–MS/MS method to simultaneously determine gemcitabine and its L-carnitine ester derivative(2’-deoxy-2’, 2’-difluoro-N-((4-amino-4-oxobutanoyl) oxy)-4-(trimethyl amm-onio) butanoate-cytidine, JDR) in rat plasma was developed and validated.The conventional plasma sample preparation method of nucleoside analogues is solidphase extraction(SPE) which is time-consuming and cost-expensive. In this study, gradient elution with small particles size solid phase was applied to effectively separate gemcitabine and JDR, and protein precipitation pretreatment was adopted to remove plasma protein and extract the analytes with high recovery(>81%). Method validation was performed as per the FDA guidelines, and the standard curves were found to be linear in the range of 5–4000 ng/ml for JDR and 4–4000 ng/ml for gemcitabine, respectively. The lower limit of quantitation(LLOQ)of gemcitabine and JDR was 4 and 5 ng/ml, respectively. The intra-day and inter-day precision and accuracy results were within the acceptable limits. Finally, the developed method was successfully applied to investigate the pharmacokinetic studies of JDR and gemcitabine after oral administration to rats. | Gang Wang Dongyang Zhao Hongxiang Chen Dawei Ding Longfa Kou Lifang Sun Chenxia Hao Xincong Li Kai Jia Qiming Kan Xiaohong Liu Zhonggui He Jin Sun | 2017 | Asian Journal of Pharmaceutical Sciences2017，12，5： | 2 |
| 13 | Molecular Epidemiology of Klebsiella pneumoniae from Clinical Bovine Mastitis in Northern Area of China,2018–2019显示文摘Klebsiella pneumoniae(K.pneumonia,KpⅠ)is a predominate inducement of bovine mastitis,which is associated with high mortality and milk yield reduction.However,data is lacking on the molecular characteristics of bovine K.pneumoniae,limiting the risk assessment of its transmission through the food chain.Herein,we investigated the prevalence of K.pneumoniae in 6301 clinical mastitis(CM)milk samples from dairy cattle in northern area of China.In total,183 K.pneumoniae isolates were recovered,with detection rates of 3.0% and 2.8% in 2018 and 2019,respectively.Like human clinical K.pneumoniae,all CM K.pneumoniae isolates belonged to one of three phylogroups:KpⅠ(n=143),Klebsiella.quasipneumoniae subsp.similipneumoniae(KpⅡ-B)(n=37),and Klebsiella variicola(KpⅢ)(n=3).We detected the extendedspectrum β-lactamase-encoding genes bla_(SHV-2a),blac_(CTX-M-14),and bla_(CTX-M-15),as well as clpC,lpfA,lacI,lacZ,lacY,and the fecABDEIR operon in the KpⅠ isolates,which may contribute to their pathogenicity and host adaptability in cows.The high prevalence of KpⅠ in dairy farms may be problematic,as it showed relatively higher rates of antibiotic resistance and virulence gene carriage than the KpⅡ-B and KpⅢ isolates.Furthermore,we observed distinct differences in population structure between CM-and human infection-associated KpⅠ isolates,with the genes associated with invasive infection in humans rarely being observed in bovine isolates,indicating that few CM-associated K.pneumoniae isolates pose a threat to human health.Nevertheless,bovine KpⅡ-B isolates shared a high level of nucleotide sequence identity with isolates from human infections and frequently carried the nitrogen-fixation gene nif,suggesting an association between KpⅡ-B isolates from cattle and humans,and plant-derived bacteria. | Shikai Song Wenjuan He Dawei Yang Manar Benmouffok Yao Wang Jiyun Li Chengtao Sun Xiangbin Song Shizhen Ma Chang Cai Shuangyang Ding Congming Wu Zhangqi Shen Yang Wang | 2022 | Engineering2022，8，3： | 1 |
| 14 | Optical, structural and thermal characteristics of Cu-CuAl2O4 hybrids deposited in anodic aluminum oxide as selective solar absorber显示文摘 | Ding Dawei Cai Weimin | 2010 | Solar Energy Mater Solar Cells2010，94，： | 1 |
| 15 | Eco-friendly and Cleaner Process Using Online Microwave-assisted Steam Extraction Coupled with Solid-phase Extraction for Trace Analysis of Sulfonamides in Animal Feed显示文摘 | LI Guijie LIU Chang WANG Dawei DING Lan | 2018 | Chemical Research in Chinese Universities2018，34，6： | 1 |
| 16 | Optimization of Al2O2/SiNx Stacked Antireflection Structure for n-type surface-passivated crystalline silicon solar cells显示文摘 | Dawei W Rui J Ding Wuchang | 2011 | Journal of Semiconductors2011，32，9： | 1 |
| 17 | Sustained delivery of endostatin improves the efficacy of therapy in lewis lung cancer model显示文摘 | WU Jinhui DING Dawei REN Guoyan | 2009 | Journal of Controlled Release2009，134，： | 1 |
| 18 | Asymmetric synthesis of c,c-disubstituted amino acids by diastereoselective functionalization of enantiopu- rephenyloxazinones, derivatives of asymmetric Strecker reaction products of aldehydes显示文摘 | Ke Ding Dawei Ma | 2001 | Tetrahedron2001，，57： | 1 |
| 19 | Filtering method for SAR interferograms with strong noise显示文摘 | Li Zhiwei Ding Xiaoli Huang Cheng Zheng Dawei W.B.ZOU Y.K.SHEA | | 0，，01： | 1 |
| 20 | Least Squares-Based Filter for Remote Sensing Image Noise Reduction显示文摘 | Li Zhiwei Ding Xiaoli Zheng Dawei Huang Cheng | | 0，，07： | 1 |
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