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| 1 | More anxious than depressed:prevalence and correlates in a 15-nation study of anxiety disorders in people with type 2 diabetes mellitus显示文摘Background Anxiety disorder, one of the highly disabling, prevalent and common mental disorders, is known to be more prevalent in persons with type 2 diabetes mellitus (T2DM) than the general population, and the comorbid presence of anxiety disorders is known to have an impact on the diabetes outcome and the quality of life. However, the information on the type of anxiety disorder and its prevalence in persons with T2DM is limited. Aims To assess the prevalence and correlates of anxiety disorder in people with type 2 diabetes in different countries. Methods People aged 18-65 years with diabetes and treated in outpatient settings were recruited in 15 countries and underwent a psychiatric interview with the Mini-International Neuropsychiatric Interview. Demographic and medical record data were collected. Results A total of 3170 people with type 2 diabetes (56.2% women;with mean (SD) duration of diabetes 10.01 (7.0) years) participated. The overall prevalence of anxiety disorders in type 2 diabetic persons was 18%;however, 2.8% of the study population had more than one type of anxiety disorder. The most prevalent anxiety disorders were generalised anxiety disorder (8.1%) and panic disorder (5.1%). Female gender, presence of diabetic complications, longer duration of diabetes and poorer glycaemic control (HbA1c levels) were significantly associated with comorbid anxiety disorder. A higher prevalence of anxiety disorders was observed in Ukraine, Saudi Arabia and Argentina with a lower prevalence in Bangladesh and India. Conclusions Our international study shows that people with type 2 diabetes have a high prevalence of anxiety disorders, especially women, those with diabetic complications, those with a longer duration of diabetes and poorer glycaemic control. Early identification and appropriate timely care of psychiatric problems of people with type 2 diabetes is warranted. | Santosh K Chaturvedi Shayanth Manche Gowda Helal Uddin Ahmed Fahad D Alosaimi Nicola Andreone Alexey Bobrov Viola Bulgari Giuseppe Carra Gianluca Castelnuovo Giovanni de Girolamo Tomasz Gondek Nikola Jovanovic Thummala Kamala Andrzej Ki Nebojsa Lalic Dusica Lecic-Tosevski Fareed Minhas Victoria Mutiso David Ndetei Golam Rabbani Suntibenchakul Somruk Sathyanarayana Srikanta Rizwan Taj Umberto Valentini Olivera Vukovic Wolfgang Wolwer Larry Cimino Arie Nouwen Cathy Lloyd Norman Sartorius | 2019 | General Psychiatry2019，32，4： | 11 |
| 2 | Clinical practice of transarterial chemoembolization for hepatocellular carcinoma:consensus statement from an international expert panel of International Society of Multidisciplinary Interventional Oncology(ISMIO)显示文摘Importance:Transarterial chemoembolization(TACE)has been associated with a wide range of practice variations for hepatocellular carcinoma(HCC)between the East and the West.This considerable ambiguity may lead to the heterogeneous quality in treatment and have a negative impact on the role of TACE in the overall multidisciplinary HCC treatment system.Objective:It may be a good start to establish a guideline worldwide to have this consensus from experts who represent east and west,although it does not cover all aspects of TACE.Evidence Review:An international expert panel on TACE is convened to cluster the expert’s opinions and summary a standard consensus.This panel committee consist of leading physicians in TACE on HCC from USA,France,Japan,Singapore,Korea,China,and so on.The first-round face-to-face consensus meeting was held during in Nanjing,China in October 2019.The second-round conference for revision of the consensus was held during the Annual Meeting of Chinese College of Interventionalists in August 2020 by a hybrid format of a Webinar and roundtable meeting.After several on-line revisions,the final manuscript was approved by all members of the panel in June 2021.Findings:The consensus statements were organized into the following categories:patients’selection,performing the procedure,TACE outcomes,repeat TACE,TACE failure/refractory,and TACE-based combination treatments.Conclusions and Relevance for Reviews:More and more evidences have showed the better outcomes with strategy of combined TACE with other local therapies such as ablations.The most-recently developing strategy of combined TACE with PD-1/PD-L1 plus tyrosine kinase inhibitor(TKI)agents has shined a light to the HCC patients,especially to those with high risk of tumor recurrence after treatment or TACE failure/refractory. | Jian Lu Ming Zhao Yasuaki Arai Bin-Yan Zhong Hai-Dong Zhu Xiao-Long Qi Thierry de Baere Uei Pua Hyun Ki Yoon David C.Madoff Gao-Jun Teng International Society of Multidisciplinary Interventional Oncology(ISMIO) | 2021 | Hepatobiliary Surgery and Nutrition2021，10，5： | 9 |
| 3 | The Effect of Own-ership Structure on Firm Performance,Additional Evidence显示文摘 | Han Ki C Suk David Y | | 0，，02： | 1 |
| 4 | Endocrine factors in the etiology of postpartum depression显示文摘 | Mi Ki B Robert C D David R R | 2003 | Comprehensive psychiatry2003，44，： | 1 |
| 5 | The Future Prospects of Microbial Cel|u- lose in Biomedical Applications显示文摘 | Wojciech K Czaja David J Young Marek Kawec- ki | 2007 | Biomacromol- ecules2007，8，1： | 1 |
| 6 | Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci显示文摘 | Trine Folseraas Espen Melum Philipp Rausch Brian D. Juran Eva Ellinghaus Alexey Shiryaev Jon K. Laerdahl David Ellinghaus Christoph Schramm Tobias J. Weismüller Daniel Nils Gotthardt Johannes Roksund Hov Ole Petter Clausen Rinse K. Weersma Marcel Janse Ki | 2012 | Journal of Hepatology2012，，2： | 1 |
| 7 | Towards an integrated global framework to assess the impacts of land use and management change on soil carbon: current capability and future vision显示文摘 | Pete Smith Christian A. Davies Stephen Ogle Giuliana Zanchi Jessica Bellarby Neil Bird Robert M. Boddey Niall P. M c Namara David Powlson Annette Cowie Meine Noordwijk Sarah C. Davis Daniel DE B. Richter Len Kryzanowski Mark T. Wijk Judith Stuart Akira Ki | 2012 | Glob Change Biol2012，，7： | 1 |
| 8 | The Arabidopsis thaliana gametophytic mutation gemini pollen1 disrupts mi- crospore polarity, division asymmetry and pollen cell fate显示文摘 | Soon Ki Park Ross Howden David Twell | 1998 | Development1998，125，： | 1 |
| 9 | The Effect of Ownership Structure on Firm Performance:Additional Evidence显示文摘 | Ki C.Han David Y.Suk | | 0，，07： | 1 |
| 10 | Effects of the mussel Mytilus edulis L. on the invertebrate fauna of sediments显示文摘 | Stefán áki Ragnarsson David Raffaelli | 1999 | Journal of Experimental Marine Biology and Ecology1999，，1： | 1 |
| 11 | Endocrine factors in the etiology of postpartum depression显示文摘 | Mi Ki B Robert C D David R R | 2003 | Comprehensive psychi- atry2003，44，： | 1 |
| 12 | Associations Between Change in Sleep Duration and Inflammation: Findings on C-reactive Protein and Interleukin 6 in the Whitehall II Study显示文摘 | Jane E. Ferrie Mika Kivim?ki Tasnime N. Akbaraly Archana Singh-Manoux Michelle A. Miller David Gimeno Meena Kumari George Davey Smith Martin J. Shipley | 2013 | American Journal of Epidemiology2013，，6： | 1 |
| 13 | Twenty‐three years of hypersensitivity pneumonitis mortality surveillance in the United States显示文摘 | Ki MoonBang David N.Weissman Germania A.Pinheiro Vinicius C.S.Antao John M.Wood GirijaSyamlal | 2006 | Am. J. Ind. Med2006，，12： | 1 |
| 14 | Preparation of an amino acid intermediate for the dipeptidyl peptidase IV inhibitor, saxagliptin, using a rood- flied phenylalanine dehydrogenase 显示文摘 | Ronald L Hanson Steven L Goldberg David B Brzozows- ki | 2007 | Adv Syrah Catal2007，349，： | 1 |
| 15 | Redox sensor QSOX1 regulates plant immunity by targeting GSNOR to modulate ROS generation显示文摘Reactive oxygen signaling regulates numerous biological processes,including stress responses in plants.Redox sensors transduce reactive oxygen signals into cellular responses.Here,we present biochemical evidence that a plant quiescin sulfhydryl oxidase homolog(QSOX1)is a redox sensor that negatively regulates plant immunity against a bacterial pathogen.The expression level of QSOX1 is inversely correlated with pathogen-induced reactive oxygen species(ROS)accumulation.Interestingly,QSOX1 both senses and regulates ROS levels by interactingn with and mediating redox regulation of S-nitrosoglutathione reductase,which,consistent with previous findings,influences reactive nitrogen-mediated regulation of ROS generation.Collectively,our data indicate that QSOX1 is a redox sensorthat negatively regulates plant immunity by linking reactive oxygen and reactive nitrogen signaling to limit ROS production. | Ho Byoung Chae Min Gab Kim Chang Ho Kang Joung Hun Park Eun Seon Lee Sang-Uk Lee Yong Hun Chi Seol Ki Paeng Su Bin Bae Seong Dong Wi Byung-Wook Yun Woe-Yeon Kim Dae-Jin Yun David Mackey Sang Yeol Lee | 2021 | Molecular Plant2021，14，8： | 1 |
| 16 | Identification of characteristic molecular signature of Müllerian inhibitingsubstance in human HPV-related cervical cancer cells显示文摘 | Seong Hwang Min Suh Joo Yoon Mee Kim Ki Ryu Suk Nam Patricia Donahoe David MacLaughlin Jang Kim | 2011 | International Journal of Oncology2011，，4： | 1 |
| 17 | The Influence of Push and Pull Factors at Korean National Parks显示文摘 | Choong Ki Lee David B Klenosky | 2003 | Tourism Management2003，24，2： | 1 |
| 18 | Integrated scanning spectrometer with a tunable micro-ring resonator and an arrayed waveguide grating显示文摘Integrated spectrometers with both wide optical bandwidths and high spectral resolutions are required in applications such as spectral domain optical coherence tomography(SD-OCT).Here we propose a compact integrated scanning spectrometer by using a tunable micro-ring resonator(MRR)integrated with a single arrayed waveguide grating for operation in the 1265-1335-nm range.The spectral resolution of the spectrometer is determined by the quality factor of the MRR,and the optical bandwidth is defined by the free spectral range of the arrayed waveguide grating.The spectrometer is integrated with on-chip germanium photodetectors,which enable direct electrical readout.A 70-nm optical bandwidth and a 0.2-nm channel spacing enabled by scanning the MRR across one free spectral range are demonstrated,which offer a total of350 wavelength channels with 31-kHz wavelength scanning speed.The integrated spectrometer is applied to measure different spectra and the interference signals from an SD-OCT system,which shows its great potential for future applications in sensing and imaging systems. | ZUNYUE ZHANG YI WANG JIARUI WANG DAN YI DAVID WENG U CHAN WU YUAN HON KI TSANG | 2022 | Photonics Research2022，10，5： | 1 |
| 19 | Iron homeostasis in astro- cytes and microglia is differentially regulated by TNF-alpha and TGF-betal 显示文摘 | Rathore KI Redensek A David S | 2012 | Glia2012，60，： | 1 |
| 20 | The Validity, Reliability and Clinical Utility of the Hong Kong Montreal Cognitive Assessment (HK-MoCA) in Patients with Cerebral Small Vessel Disease显示文摘 | Wong Adrian Xiong Yun Y Kwan Pauline W L Chan Anne Y Y Lam Wynnie W M Wang Ki Chu Winnie C W Nyenhuis David L Nasreddine Ziad Wong Lawrence K S Mok Vincent C T | 2009 | Dementia and Geriatric Cognitive Disorders2009，，1： | 1 |
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