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106篇 您的检索式:作者名="David JA"
    题名 作者 年代 出处 被引量
1Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics显示文摘交往受体的蛋白质 kinase-3 (RIP3 或 RIPK3 ) 是执行 “ 的细胞的机械的必要部分; programmed”或 “ regulated”坏死。这里,我们证明那规划坏死响应许多化学疗法的代理人被激活并且贡献导致化疗的房间死亡。然而,我们证明那 RIP3 表情经常在化学疗法的死亡期间由于它的 transcriptional 开始地点, MLKL 的这样 RIP3 依赖的激活和下游地规划的坏死附近的 genomic methylation 是在癌症房间的 silenced 大部分被镇压。不过,有 hypomethylating 代理人的治疗恢复 RIP3 表示,并且从而以一种 RIP3 依赖的方式把敏感提升到 chemotherapeutics。RIP3 表示在 85% 乳癌病人与正常织物相比在肿瘤被减少,建议那 RIP3 缺乏断然在肿瘤生长 / 发展期间被选择。因为 hypomethylating 代理人在病人是相当容忍得好的,我们建议病人们可以从收到 hypomethylating 代理人与常规 chemotherapeutics 在治疗以前导致 RIP3 表示有益于的那 RIP3 缺乏的癌症。Gi-Bang Koo Michael J Morgan Da-Gyum Lee Woo-Jung Kim Jung-Ho Yoon Ja Seung Koo Seung I1 Kim Soo Jung Kim Mi Kwon Son Soon Still Hong Jean M Mulcahy Levy Daniel A Pollyea Craig T Jordan Pearlly Yan David Frankhouser Deedra Nicolet Kati Maharry Guido Marcucci Kyeong Sook Choi Hyeseong Cho ndrew Thorbum You-Sun Kim 2015Cell Research2015,25,6:20
2Cerebral blood volume maps of gliomas: comparison with tumor grade and histologic findings显示文摘Hannu JA Inna EG David NL 1994Radiology1994,191,1:2
3The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a celldeath pathway characterized by cleavage of Bid and production of reactive oxygen species显示文摘Astrid AR Michael JA David 2001Proc Natl Acad Sci USA2001,98,10:1
4A comparison of remifentanil and fentanyl for fast track paediatric cardiac anaesth显示文摘Robert HF Andrew SV David JA 2003Paediatr Anaesth2003,13,2:1
5The prognostic value of B-type natriuretic peptide in patient with acute coronary syndromes显示文摘James A De Lemos JA David A 2001N Engl J Med2001,345,:1
6Effect ofheparin surface modification in reducing silicone oil adherence to various intraocular lenses显示文摘Stelh NA Peng Q David JA 2001J Cataract Refract Surg2001,27,10:1
7Annual health outcomes and treatment costs for schizophrenia populations显示文摘Mauskopf JA David K Grainger DL ct al 1999J Clin Psychia-try1999,60,19:1
8The NIH human microbiome project显示文摘NIH HMP Working Group Peterson J Garges S Giovanni M McInnes P Wang L Schloss JA Bonazzi V McEwen JE Wetterstrand KA Deal C Baker CC Di Francesco V Howcroft TK Karp RW Lunsford RD Wellington CR Belachew T Wright M Giblin C David H Mills M Salomon R Mullins C Akolkar B Begg L Davis C Grandison L Humble M Khalsa J Little AR Peavy H Pontzer C Portnoy M Sayre MH Starke-Reed P Zakhari S Read J Watson B Guyer M 2009Genome Res2009,19,12:1
9Sep to ptic dysplasis: MR Imaging 显示文摘Barkovich JA Fram EK David N 1989Radiology1989,171,:1
10Cisplatin ototoxicity 显示文摘Jodie LN David JA Craig WN 1999Am J Clin Oncol1999,22,3:1
11Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America显示文摘Thomas JW Elias JA David WD 2008Clin Infect Dis2008,46,:1
12Merkel cell carcinoma: prognosis and treatment of patients from a single institution 显示文摘Peter JA Wilbur BB David PJ 2005J Clin Oncol2005,23,10:1
13The behavior of landscape metrics commonly used in the study of habitat fragmentation显示文摘ARGIS CD BISSONETrE JA DAVID JL 1998Landscape Ecology1998,13,3:1
14High-dose ibuprofen for reduction of striatal infarcts during middle cerebral artery occlusion in rats显示文摘David FA Richard EC Nabil JA 2003J Neurosurg2003,98,4:1
15New approaches to prevention and treatment of radial artery graft vasospasm显示文摘 Cable DG Caccitolo JA 1999Circulation1999,19,:1
16Ischemic preconditioning reduces apoptosis by upregulating antideath gene bcl-2显示文摘Maulik N David Engelman RM Rousou JA 1999circulation1999,13,:1
17Population comparison of two clinical approaches to the metabolic syndrome显示文摘Robert JA Sarah A David HW 0,,11:1
18The link between dietary fibre and human health显示文摘Cyril W C Kendall Amin Esfahani David JA Jenkins 2010Food Hydrocolloids2010,24,:1
19Colorectal cancer screening 显示文摘Burr RW Cannon JA David DS 2013J Natl Comor Cane Netw2013,11,12:1
20Annual health outcomes and treatment costs for schizophrenia populations显示文摘Mauskopf JA David K Grainger DL 1999J Clin Psychia- try1999,60,19:1
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