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| 1 | 皮肤病摄影的回顾和展望显示文摘医学知识最早由文字或绘画记载,皮肤病学亦是如此,已知最早被绘画记载的皮肤病是梅毒。很多著名皮肤病学家如Ferdinand Hebra(1816--1880年,Vienna皮肤病学校创立者)、Moritz Kaposi(1837—1902年,最早研究红斑狼疮、扁平苔藓等疾病, | 崔勇 W.P. Daniel Su Mark D.P. Davis Mark R. Pittelkow 张学军 | 2011 | 中华皮肤科杂志2011，44，10： | 8 |
| 2 | Ground response to high horizontal stresses during longwall retreat and its implications for longwall headgate support显示文摘Roof falls in longwall headgate can occur when weak roof and high horizontal stress are present. To prevent roof falls in the headgate under high horizontal stress, it is important to understand the ground response to high horizontal stress in the longwall headgate and the requirements for supplemental roof support. In this study, a longwall headgate under high horizontal stress was instrumented to monitor stress change in the pillars, deformations in the roof, and load in the cable bolts. The conditions in the headgate were monitored for about six months as the longwall face passed by the instrumented site.The roof behavior in the headgate near the face was carefully observed during longwall retreat.Numerical modeling was performed to correlate the modeling results with underground observation and instrumentation data and to quantify the effect of high horizontal stress on roof stability in the longwall headgate. This paper discusses roof support requirements in the longwall headgate under high horizontal stress in regard to the pattern of supplemental cable bolts and the critical locations where additional supplemental support is necessary. | Peter Zhang Dave Gearhart Mark Van Dyke Daniel Su Essie Esterhuizen Berk Tulu | 2019 | International Journal of Mining Science and Technology2019，29，1： | 6 |
| 3 | Non-spherical multi-oscillations of a bubble in a compressible liquid显示文摘Bubble dynamics are associated with wide and important applications in cavitation erosion in many industrial systems, medical ultrasonics and underwater explosions. Two recent developments to this classical problem are reviewed in this paper. Firstly, computational studies on the problem have commonly been based on an incompressible fluid model. However, a bubble usually undergoes significantly damped oscillation due to the compressible effects. We model this phenomenon using weakly compressible theory and a modified boundary integral method. This model considers the energy loss due to shock waves emitted at minimum bubble volumes. Secondly, the computational studies so far have largely been concerned with the first-cycle of oscillation. However, a bubble usually oscillates for a few cycles before it breaks into much smaller ones. We model both the first- and second-cycles of oscillationand predict damped oscillations. Our computations correlate well with the experimental data. | WANG Qian-xi YANG Yuan-xiang TAN Danielle SU Jian TAN Soon Keat | 2014 | Journal of Hydrodynamics2014，26，6： | 4 |
| 4 | Mars Ion and Neutral Particle Analyzer (MINPA) for Chinese Mars Exploration Mission (Tianwen-1): Design and ground calibration显示文摘The main objective of the Mars Ion and Neutral Particle Analyzer(MINPA)aboard the Chinese Mars Exploration Mission(Tianwen-1)is to study the solar wind-Mars interaction by measuring the ions and energetic neutral atoms(ENAs)near Mars.The MINPA integrates ion and ENA measurements into one sensor head,sharing the same electronics box.The MINPA utilizes a standard toroidal top-hat electrostatic analyzer(ESA)followed by a time of flight(TOF)unit to provide measurement of ions with energies from 2.8 eV to 25.9 keV and ENAs from 50 eV to 3 keV with a base time resolution of 4 seconds.Highly polished silicon single crystal substrates with an Al2O3 film coating are used to ionize the ENAs into positive ions.These ions can then be analyzed by the ESA and TOF,to determine the energy and masses of the ENAs.The MINPA provides a 360°×90°field of view(FOV)with 22.5°×5.4°angular resolution for ion measurement,and a 360°×9.7°FOV with 22.5°×9.7°angular resolution for ENA measurement.The TOF unit combines a-15 kV acceleration high voltage with ultra-thin carbon foils to resolve H+,He2+,He+,O+,O2+and CO2+for ion measurement and to resolve H and O(≥16 amu group)for ENA measurement.Here we present the design principle and describe our ground calibration of the MINPA. | LingGao Kong AiBing Zhang Zhen Tian XiangZhi Zheng WenJing Wang Bin Liu Peter Wurz Daniele Piazza Adrian Etter Bin Su YaYa An JianJing Ding WenYa Li Yong Liu Lei Li YiRen Li Xu Tan YueQiang Sun | 2020 | Earth and Planetary Physics2020，4，4： | 4 |
| 5 | Transitional geology and its effects on development and longwall mining in Pittsburgh Seam显示文摘This paper presents the geologic and ground control challenges that were encountered by Consol Energy's coal mining operations in southwestern Pennsylvania,USA. Geologic encounters,such as sandstoneto-limestone geology transition,massive sandstone channels,shale channels,pyritic rich green claystone,laminated roof,and soft floor,have significantly impacted the development and longwall mining in Consol's Pittsburgh Seam coal mines. Experience from different mines shows that,in the sandstone-to-limestone geology transition zone,1.83 m high-tension,fully-grouted primary bolts employed along with 4.88 m center cable bolts at every other strap greatly improved beam building and ensured proper anchorage into the competent roof. Hydraulic fracturing of the massive sandstone was often necessary to enhance caving of the massive sandstone behind the shields to relieve pressure at the face. The presence of soft floor coupled with presence of thick floor coal and deep cover,induced excessive headgate convergence during retreat of the first right hand longwall panel. In all,it is important to explore the roof and in-seam geology in detail to delineate normal and anomalous geologic conditions prior to and during development. With diligent geologic reconnaissance,geotechnical monitoring,and assessment,site-specific geotechnical solutions have been provided to mine operations to improve safety and productivity. | Lu Jun Van Dyke Mark Su Daniel W.H. Hasenfus Greg | 2016 | International Journal of Mining Science and Technology2016，26，1： | 3 |
| 6 | Inhibition of CDK9 by voruciclib synergistically enhances cell death induced by the Bcl-2 selective inhibitor venetoclax in preclinical models of acute myeloid leukemia显示文摘Venetoclax,an FDA-approved Bcl-2 selective inhibitor for the treatment of chronic lymphocytic leukemia and acute myeloid leukemia(AML),is tolerated well in elderly patients with AML and has good overall response rates;however,resistance remains a concern.In this study,we show that targeting CDK9 with voruciclib in combination with venetoclax results in synergistic antileukemic activity against AML cell lines and primary patient samples.CDK9 inhibition enhances venetoclax activity through downregulation of Mcl-1 and c-Myc.However,downregulation of Mcl-1 is transient,which necessitates an intermittent treatment schedule to allow for repeated downregulation of Mcl-1.Accordingly,an every other day schedule of the CDK9 inhibitor is effective in vitro and in vivo in enhancing the efficacy of venetoclax.Our preclinical data provide a rationale for an intermittent drug administration schedule for the clinical evaluation of the combination treatment for AML. | Daniel A.Luedtke Yongwei Su Jun Ma Xinyu Li Steven ABuck Holly Edwards Lisa Polin Juiwanna Kushner Sijana HDzinic Kathryn White Hai Lin Jeffrey WTaub Yubin Ge | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 3 |
| 7 | Targeted Epithelial Tight Junction Dysfunction Causes Immune Activation and Contributes to Development of Experimental Colitis显示文摘 | Liping Su Le Shen Daniel R. Clayburgh Sam C. Nalle Erika A. Sullivan Jon B. Meddings Clara Abraham Jerrold R. Turner | 2009 | Gastroenterology2009，，2： | 2 |
| 8 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 9 | Donor-specific cell-free DNA as a biomarker in liver transplantation:A review显示文摘Due to advances in modern medicine,liver transplantation has revolutionised the prognosis of many previously incurable liver diseases.This progress has largely been due to advances in immunosuppressant therapy.However,despite the judicious use of immunosuppression,many liver transplant recipients still experience complications such as rejection,which necessitates diagnosis via invasive liver biopsy.There is a clear need for novel,minimally-invasive tests to optimise immunosuppression and improve patient outcomes.An emerging biomarker in this‘‘precision medicine’‘liver transplantation field is that of donorspecific cell free DNA.In this review,we detail the background and methods of detecting this biomarker,examine its utility in liver transplantation and discuss future research directions that may be most impactful. | Tess McClure Su Kah Goh Daniel Cox Vijayaragavan Muralidharan Alexander Dobrovic Adam G Testro | 2020 | World Journal of Transplantation2020，10，11： | 2 |
| 10 | 一种头部磁共振图像自动配准方法显示文摘提出一种基于曲线形状匹配的头部磁共振图像自动配准方法,可实现预分割提取头部轮廓曲线、曲线形状特征提取及匹配和单层匹配结果的校正。实验证明在缺乏成像位置参数时,该方法可快速有效地成功实现头部磁共振图像的配准,特别是颅脑内部包含肿瘤的图像配准。 | 邓莹莹 廖庆敏 李永 Su Ruan Daniel Bloyet | 2003 | 计算机应用2003，23，5： | 2 |
| 11 | Influence of longwall mining on the stability of gas wells in chain pillars显示文摘Longwall mining has a significant influence on gas wells located within longwall chain pillars.Subsurface subsidence and abutment pressure induced by longwall mining can cause excessive stresses and deformations in gas well casings.If the gas well casings are compromised or ruptured,natural gas could migrate into the mine workings,potentially causing a fire or explosion.By the current safety regulations,the gas wells in the chain pillars have to be either plugged or protected by adequate coal pillars.The current regulations for gas well pillar design are based on the 1957 Pennsylvania gas well pillar study.The study provided guidelines for gas well pillars by considering their support area and overburden depth as well as the location of the gas wells within the pillars.As the guidelines were developed for room-andpillar mining under shallow cover,they are no longer applicable to modern longwall coal mining,particularly,under deep cover.Gas well casing of failures have occurred even though the chain pillars for the gas wells met the requirements by the 1957 study.This study,conducted by the National Institute for Occupational Safety and Health(NIOSH),presents seven cases of conventional gas wells penetrating through longwall chain pillars in the Pittsburgh Coal Seam.The study results indicate that overburden depth and pillar size are not the only determining factors for gas well stability.The other important factors include subsurface ground movement,overburden geology,weak floor,as well as the type of the construction of gas wells.Numerical modeling was used to model abutment pressure,subsurface deformations,and the response of gas well casings.The study demonstrated that numerical models are able to predict with reasonable accuracy the subsurface deformations in the overburden above,within,and below the chain pillars,and the potential location and modes of gas well failures,thereby providing a more quantifiable approach to assess the stability of the gas wells in longwall chain pillars. | Peter Zhang Heather Dougherty Daniel Su Jack Trackemas Berk Tulu | 2020 | International Journal of Mining Science and Technology2020，30，1： | 2 |
| 12 | Experimental investigation of the Zn-Fe-V system at450℃显示文摘 | Wu Changjun Su Xuping Liu Daniel | 2010 | International Journal of MaterialsResearch2010，101，12： | 1 |
| 13 | Immunomagnetic separation and detection of Salmonella cells using newly designed carriers显示文摘 | Alena ?panová Bohuslav Rittich Daniel Horák Ji??? Lenfeld Jana Prodělalová Jana Su?iková Soňa ?trumcová | 2003 | Journal of Chromatography A2003，，1： | 1 |
| 14 | Pegasus: A framework for mapping complex scientific workflows onto distributed systems显示文摘 | Ewa Deelman Gurmeet Singh Mei-Hui Su James Blythe Yolanda Gil Carl Kesselman Gaurang Mehta Karan Vahi G. Bruce Berriman John Good Anastasia Laity Joseph C. Jacob Daniel S. Katz | 2005 | Scientific Programming2005，，3： | 1 |
| 15 | Anti-VEGF therapy for the treatment of glaucoma: a focus on ranibizumab and bevacizumab显示文摘 | Sung Chul Park Daniel Su Celso Tello | 2012 | Expert Opinion on Biological Therapy2012，，12： | 1 |
| 16 | Mapping ideas from cyberspace to realspace: visualizing the spatial context of keywords from web page search results显示文摘We introduce a new method for visualizing and analyzing information landscapes of ideas and events posted on public web pages through customized web-search engines and keywords.This research integrates GIScience and web-search engines to track and analyze public web pages and their web contents with associated spatial relationships.Web pages searched by clusters of keywords were mapped with real-world coordinates(by geolocating their Internet Protocol addresses).The resulting maps represent web information landscapes consisting of hundreds of populated web pages searched by selected keywords.By creating a Spatial Web Automatic Reasoning and Mapping System prototype,researchers can visualize the spread of web pages associated with specific keywords,concepts,ideas,or news over time and space.These maps may reveal important spatial relationships and spatial context associated with selected keywords.This approach may provide a new research direction for geographers to study the diffusion of human thought and ideas.A better understanding of the spatial and temporal dynamics of the‘collective thinking of human beings’over the Internet may help us understand various innovation diffusion processes,human behaviors,and social movements around the world. | Ming-Hsiang Tsou Ick-Hoi Kim Sarah Wandersee Daniel Lusher Li An Brian Spitzberg Dipak Gupta Jean Mark Gawron Jennifer Smith Jiue-An Yang Su Yeon Han | 2014 | International Journal of Digital Earth2014，7，4： | 1 |
| 17 | Microcavity exciton polaritons at room temperature显示文摘The quest for realizing novel fundamental physical effects and practical applications in ambient conditions has led to tremendous interest in microcavity exciton polaritons working in the strong coupling regime at room temperature.In the past few decades,a wide range of novel semiconductor systems supporting robust exciton polaritons have emerged,which has led to the realization of various fascinating phenomena and practical applications.This paper aims to review recent theoretical and experimental developments of exciton polaritons operating at room temperature,and includes a comprehensive theoretical background,descriptions of intriguing phenomena observed in various physical systems,as well as accounts of optoelectronic applications.Specifically,an in-depth review of physical systems achieving room temperature exciton polaritons will be presented,including the early development of ZnO and GaN microcavities and other emerging systems such as organics,halide perovskite semiconductors,carbon nanotubes,and transition metal dichalcogenides.Finally,a perspective of outlooking future developments will be elaborated. | Sanjib Ghosh Rui Su Jiaxin Zhao Antonio Fieramosca Jinqi Wu Tengfei Li Qing Zhang Feng Li Zhanghai Chen Timothy Liew Daniele Sanvitto Qihua Xiong | 2022 | Photonics Insights2022，1，1： | 1 |
| 18 | Zircon Trace Element Constraints on the Evolution of the Paleoproterozoic Birimian Granitoids of the West African Craton(Ghana)显示文摘The Paleoproterozoic Birimian granitoids of the West African Craton(WAC) in the northwestern part of Ghana, have been studied for their zircon trace elements concentrations to infer the source characteristics, origin, and magmatic evolution. The zircons in the granitoids have Th/U ratios ranging from 0.03 to 1.55, and display depleted light rare earth elements(LREE) and enriched heavy rare earth elements(HREE) contents, characterized by pronounced positive to negative anomalies of Eu(Eu/Eu~*=0.14–0.98 and 1.01–6.06, respectively) and Ce(Ce/Ce~*=0.08–0.98 and 1.02–116, respectively), which may imply that they were derived from both magmatic and hydrothermal sources. The geochemical plots of U/Yb vs. Y and Hf, the positive correlation between Hf and the other high field strength elements(HFSE) and high rare earth elements(REE) contents, with enrichment in Ce and depletion in Eu, indicate that the granitoids possibly formed from partial melting of the crust. The trace elements characteristics(i.e., wide range of Hf, Ce/Ce~*, Th/U and Zr/Hf values) of the zircons suggest that crystallization of the magma occurred under variable oxidation states, which spanned over a longer period, implying that our data corroborate interpretations from studies of whole-rock geochemistry and geochronology on the granitoids of northwestern Ghana. This further indicates that the evolution of the Birimian granitoids in this part of the WAC occurred earlier than what had been reported in the literature. | Patrick Asamoah Sakyi Benxun Su Daniel Kwayisi Chen Chen Yang Bai Melesse Alemayehu | 2018 | Journal of Earth Science2018，29，1： | 1 |
| 19 | Chronic cola drinking induces metabolic and cardiac alterations in rats显示文摘AIM: To investigate the effects of chronic drinking of cola beverages on metabolic and echocardiographic parameters in rats. METHODS: Forty-eight male Wistar rats were divided in 3 groups and allowed to drink regular cola (C), diet cola (L), or tap water (W) ad libitum during 6 mo. After this period, 50% of the animals in each group were euthanized. The remaining rats drank tap water ad libitum for an additional 6 mo and were then sacrificed. Rat weight, food, and beverage consumption were measured regularly. Biochemical, echocardiographic and systolic blood pressure data were obtained at baseline, and at 6 mo (treatment) and 12 mo (washout). A complete histopathology study was performed after sacrifice. RESULTS: After 6 mo, C rats had increased body weight (+7%, P < 0.01), increased liquid consumption (+69%, P < 0.001), and decreased food intake (-31%, P < 0.001). C rats showed mild hyperglycemia and hypertriglyceridemia. Normoglycemia (+69%, P < 0.01) and sustained hypertriglyceridemia (+69%, P < 0.01) were observed in C after washout. Both cola beverages induced an increase in left ventricular diastolic diameter (C: +9%, L: +7%, P < 0.05 vs W) and volumes (diastolic C: +26%, L: +22%, P < 0.01 vs W; systolic C: +24%, L: +24%, P < 0.05 vs W) and reduction of relative posterior wall thickness (C: -8%, L: -10%, P < 0.05 vs W). Cardiac output tended to increase (C: +25%, P < 0.05 vs W; L: +17%, not significant vs W). Heart rate was not affected. Pathology findings were scarce, related to aging rather than treatment. CONCLUSION: This experimental model may prove useful to investigate the consequences of high consumption of soft drinks. | José Milei Matilde Otero Losada Hernán Gómez Llambí Daniel R Grana Daniel Suárez Francisco Azzato Giuseppe Ambrosio | 2011 | World Journal of Cardiology2011，3，4： | 1 |
| 20 | m6A-TSHub:Unveiling the Context-specific m^(6)A Methylation and m^(6)A-affecting Mutations in 23 Human Tissues显示文摘As the most pervasive epigenetic marker present on mRNAs and long non-coding RNAs(lncRNAs),N6-methyladenosine(m^(6)A)RNA methylation has been shown to participate in essential biological processes.Recent studies have revealed the distinct patterns of m^(6)A methylome across human tissues,and a major challenge remains in elucidating the tissue-specific presence and circuitry of m^(6)A methylation.We present here a comprehensive online platform,m^(6)A-TSHub,for unveiling the context-specific m^(6)A methylation and genetic mutations that potentially regulate m^(6)A epigenetic mark.m^(6)A-TSHub consists of four core components,including(1)m^(6)A-TSDB,a comprehensive database of 184,554 functionally annotated m^(6)A sites derived from 23 human tissues and 499,369 m^(6)A sites from 25 tumor conditions,respectively;(2)m^(6)A-TSFinder,a web server for high-accuracy prediction of m^(6)A methylation sites within a specific tissue from RNA sequences,which was constructed using multi-instance deep neural networks with gated attention;(3)m^(6)ATSVar,a web server for assessing the impact of genetic variants on tissue-specific m^(6)A RNA modifications;and(4)m^(6)A-CAVar,a database of 587,983 The Cancer Genome Atlas(TCGA)cancer mutations(derived from 27 cancer types)that were predicted to affect m^(6)A modifications in the primary tissue of cancers.The database should make a useful resource for studying the m^(6)A methylome and the genetic factors of epitranscriptome disturbance in a specific tissue(or cancer type).m^(6)A-TSHub is accessible at www.xjtlu.edu.cn/biologicalsciences/m^(6)ats. | Bowen Song Daiyun Huang Yuxin Zhang Zhen Wei Jionglong Su João Pedro de Magalhães Daniel J.Rigden Jia Meng Kunqi Chen | 2023 | Genomics, Proteomics & Bioinformatics2023，21，4： | 1 |
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