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| 1 | Antifibrotic effect of heparin on liver fibrosis model in rats显示文摘AIM: To evaluate the effect of chronic thrombin inhibition by heparin on experimentally induced chronic liver injury (liver fibrosis) in rats. METHODS: Chronic liver injury (liver fibrosis) was induced in Wistar rats by oral administration of carbon tetrachloride (CCl 4 ) for 7 wk, an animal model with persistent severe hepatic fibrosis. Intravenous administration of the thrombin antagonist (heparin) started 1 wk after the start of CCl 4 intoxication for 6 wk. After completion of treatment (7 wk), markers of hepatic dysfunction were measured and changes evaluated histopathologically. RESULTS: Higher serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), alkaline phosphatase (ALP), total, direct and indirect bilirubin levels, as well as lower fibrinogen levels, were found in CCl 4 intoxicated rats. Heparin, silymarin and combination of drug (heparin and silymarin) treatment for 6 wk prevented a rise in SGOT, SGPT, ALP, total, direct and indirect bilirubin levels and improved fibrinogen levels. Deterioration in hepatic function determined by the fibrosis area was retarded, as evident from hepatic histopathology. Total protein levels were not changed in all groups.CONCLUSION: Heparin, a thrombin antagonist, preserved hepatic function and reduced severity of hepatic dysfunction/fibrogenesis. Combination of heparin and silymarin produced additional benefits on liver fibrosis. | Binita Shah Gaurang Shah | 2012 | World Journal of Gastrointestinal Pharmacology and Therapeutics2012，3，6： | 5 |
| 2 | Removal of Fluoride from Aqueous Solution by CaO Nanoparticles 显示文摘 | Gaurang Patel Usha Pal Shobhana Menon | 2009 | Separation Science and Technology2009，44，12： | 1 |
| 3 | Pegasus: A framework for mapping complex scientific workflows onto distributed systems显示文摘 | Ewa Deelman Gurmeet Singh Mei-Hui Su James Blythe Yolanda Gil Carl Kesselman Gaurang Mehta Karan Vahi G. Bruce Berriman John Good Anastasia Laity Joseph C. Jacob Daniel S. Katz | 2005 | Scientific Programming2005，，3： | 1 |
| 4 | Impact of temporary hilar clamping during laparoscopic partial nephrectomy on postoperative renal function:a prospective study显示文摘 | Shah Gaurang Upadhyay Jyoti | 2004 | J Urol2004，172，： | 1 |
| 5 | Cerebral perfusion CT:Technique and Clinical Applications显示文摘 | Ellen GH Rajan J Gaurang VS | 2004 | Radiology2004，231，3： | 1 |
| 6 | Salpingectomy increases peri-implantation endometrial HOXA10 expression in women with hydrosalpinx显示文摘 | Gaurang S. Daftary Umit Kayisli Emre Seli Orhan Bukulmez Aydin Arici Hugh S. Taylor | 2007 | Fertility and Sterility2007，，2： | 1 |
| 7 | Endocrine Regulation of HOX Genes 显示文摘 | Gaurang S Daftary Taylor | 2006 | Reproductive Endocrinology2006，27，4： | 1 |
| 8 | Planning percutaneous nephrolithotomy using multidetector computed tomography urography,multiplanar reconstruction and three-dimensional reformatting显示文摘 | Nikesh T Hugh M Gaurang U | 2005 | BJU International2005，95，： | 1 |
| 9 | Planning percutaneous nephrolithotomy using multidetector computed tomography urography,multiplanar reconstruction and three-dimensional reformatting显示文摘 | Nikesh T Hugh M Gaurang U | 2005 | BJU Int2005，95，9： | 1 |
| 10 | Hydrosalpinx fluid diminishes endometrial cell HOXA 10 express-ion显示文摘 | Gaurang S Daftary MD Hugh S | 2002 | Fertil Steril2002，78，3： | 1 |
| 11 | Equity valuation art or science? 显示文摘 | Trived Gaurang S | 2003 | AFP Exchange2003，23，5： | 1 |
| 12 | Ureteral Access Sheath for the Management of Pediatric Renal and Ureteral Stones: A Single Center Experience显示文摘 | Amar Singh Gaurang Shah Jennifer Young Maryellen Sheridan Gabriel Haas Jyoti Upadhyay | 2006 | The Journal of Urology2006，，3： | 1 |
| 13 | Laparoendoscopic Single-site Repair of Retrocaval Ureter: First Case Report显示文摘 | Riccardo Autorino Rakesh Khanna Michael A. White Georges-Pascal Haber Gaurang Shah Jihad H. Kaouk Robert J. Stein | 2010 | Urology2010，，6： | 1 |
| 14 | Impact of temporary hilar clamping during laparoscopie partial ne- phrectomy on postoperative renal function: a prospective study 显示文摘 | Shekarriz Bijan Shah Gaurang Upadhyay Jyoti | 2004 | J Urol2004，172，： | 1 |
| 15 | 提高家用电器电机的工作效率显示文摘众所周知,电机是许多家用电器产品重要部件之一。从冰箱、微波炉直到洗衣机和滚筒烘衣机在内的众多家用电器中经常要用到电机,特别是交流感应电机(ACIM)。家用电器电机的驱动效率一直是用户关注的焦点,因此,如何提高家用电器电机的工作效率便被提上了日程。 | Cheri Keller Gaurang Kavaiya | 2004 | 电子测试(新电子)2004，，8： | 1 |
| 16 | Mapping Abstract Complex Workflows onto Grid Environments显示文摘 | Ewa Deelman James Blythe Yolanda Gil Carl Kesselman Gaurang Mehta Karan Vahi Kent Blackburn Albert Lazzarini Adam Arbree Richard Cavanaugh Scott Koranda | 2003 | Journal of Grid Computing2003，，1： | 1 |
| 17 | Determination of mycophenolic acid in human plasma by ultra performance liquid chromatography tandem mass spectrometry显示文摘A simple, sensitive and high throughput ultra performance liquid chromatography tandem mass spectrometry method has been developed for the determination of mycophenolic acid in human plasma. The method involved simple protein precipitation of MPA along with its deuterated analog as an internal standard(IS) from 50 mL of human plasma. The chromatographic analysis was done on Acquity UPLC C18(100 mm 2.1 mm, 1.7 mm) column under isocratic conditions using acetonitrile and 10 mM ammonium formate, pH 3.00(75:25, v/v) as the mobile phase. A triple quadrupole mass spectrometer operating in the positive ionization mode was used for quantitation. In-source conversion of mycophenolic glucuronide metabolite to the parent drug was selectively controlled by suitable optimization of cone voltage, cone gas flow and desolvation temperature. The method was validated over a wide concentration range of 15–15000 ng/mL. The mean extraction recovery for the analyte and IS was 495%. Matrix effect expressed as matrix factors ranged from 0.97 to 1.02. The method was successfully applied to support a bioequivalence study of 500 mg mycophenolate mofetil tablet in 72 healthy subjects. | Vivek Upadhyay Vikas Trivedi Gaurang Shah Manish Yadav Pranav S.Shrivastav | 2014 | Journal of Pharmaceutical Analysis2014，4，3： | 1 |
| 18 | Preparation and evaluation of hepatic stellate cell selective, surface conjugated, peroxisome proliferator-activated receptor-gamma ligand loaded liposomes显示文摘 | Gaurang Patel Gitanjali Kher Ambikanandan Misra | 2012 | Journal of Drug Targeting2012，，2： | 1 |
| 19 | Rapid and Sensitive UPLC–MS-MS Determination of Tacrolimus in Wistar Rats and Human Blood显示文摘 | Vivek Upadhyay Vikas Trivedi Gaurang Shah Manish Yadav Pranav S. Shrivastav | 2014 | Journal of Chromatographic Science2014，，1： | 1 |
| 20 | Xanthogranulomatous cystitis显示文摘 | Rajiv G Gaurang K Amit D | 2007 | Int Urol Nephrol2007，39，： | 1 |
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