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| 1 | Glutamine prevents oxidative stress in a model of mesenteric ischemia and reperfusion显示文摘AIM: To evaluate preventative effects of glutamine in an animal model of gut ischemia/reperfusion(I/R).METHODS: Male Wistar rats were housed in a controlled environment and allowed access to food and water ad libitum. Twenty male Wistar rats were divided into four experimental groups:(1) control group(control)- rats underwent exploratory laparotomy;(2) control + glutamine group(control-GLU)- rats were subjected to laparotomy and treated intraperitoneally with glutamine 24 and 48 h prior to surgery;(3) I/R group- rats were subjected to occlusion of the superior mesenteric artery for 30 min followed by 15 min of reperfusion; and(4) ischemia/reperfusion + glutamine group(G + I/R)- rats were treated intraperitoneally with glutamine 24 and 48 h before I/R. Local and systemic injuries were determined by evaluating intestinal and lung segments for oxidative stress using lipid peroxidation and the activity of superoxide dismutase(SOD), interleukin-6(IL-6) and nuclear factor kappa beta(NFkB) after mesenteric I/R. RESULTS: Lipid peroxidation of the membrane was increased in the animals subjected to I/R(P < 0.05). However, the group that received glutamine 24 and 48 h before the I/R procedure showed levels of lipid peroxidation similar to the control groups(P < 0.05). The activity of the antioxidant enzyme SOD was decreased in the gut of animals subjected to I/R when compared with the control group of animals not subjected to I/R(P < 0.05). However, the group that received glutamine 24 and 48 h before I/R showed similar SOD activity to both control groups not subjected to I/R(P < 0.05). The mean area of NF-kB staining for each of the control groups was similar. The I/R group showed the largest area of staining for NF-kB. The G + I/R group had the second highest amount of staining, but the mean value was much lower than that of the I/R group(P < 0.05). For IL-6, control and control-GLU groups showed similar areas of staining. The I/R group contained the largest area of IL-6 staining, followed by the G + I/R animals; however, this area was significantly lower than that of the group that underwent I/R without glutamine(P < 0.05). CONCLUSION: These results demonstrate that pretreatment with glutamine prevents mucosal injury and improves gut and lung recovery after I/R injury in rats. | Gilmara Pandolfo Zabot Gustavo Franco Carvalhal Norma Possa Marroni Renata Minuzzo Hartmann Vinícius Duval da Silva Henrique Sarubbi Fillmann | 2014 | World Journal of Gastroenterology2014，20，32： | 7 |
| 2 | 非抗菌素法防治奶牛乳腺炎显示文摘前言 乳腺炎是影响乳牛生产的一种常见病,主要产奶国家的一份调查显示,每年有15%-20%的奶牛患乳腺炎。抗菌素治疗乳腺炎不是一个好办法,除了抗菌素残余和影响牛奶质量外,还会产生耐药性菌株。生态农业上通常不准使用抗菌素,但仍有许多预防、治疗乳腺炎的措施,现简介如下: 一、引起乳腺炎的微生物 奶牛乳房上和乳腺内约有137种微生物。多数种属于正常的,不引起乳腺炎,90%的乳腺炎是由少数几种微生物引起,主要有传染性微生物(无乳链球菌。 | Jean Duval 傅小平 | 2001 | 乳业科学与技术2001，24，1： | 4 |
| 3 | Glutamine prevents oxidative stress in a model of portal hypertension显示文摘AIM To evaluate the protective effects of glutamine in a model of portal hypertension(PH) induced by partial portal vein ligation(PPVL).METHODS Male Wistar rats were housed in a controlled environment and were allowed access to food and water ad libitum. Twenty-four male Wistar rats were divided into four experimental groups:(1) control group(SO)-rats underwent exploratory laparotomy;(2) control + glutamine group(SO + G)-rats were subjected to laparotomy and were treated intraperitoneally with glutamine;(3) portal hypertension group(PPVL)-rats were subjected to PPVL; and(4) PPVL + glutamine group(PPVL + G)-rats were treated intraperitoneally with glutamine for seven days. Local injuries were determined by evaluating intestinal segments for oxidative stress using lipid peroxidation and the activities of glutathione peroxidase(GPx), endothelial nitric oxide synthase(e NOS) and inducible nitric oxide synthase(i NOS) after PPVL.RESULTS Lipid peroxidation of the membrane was increased in the animals subjected to PH(P < 0.01). However, the group that received glutamine for seven days after the PPVL procedure showed levels of lipid peroxidation similar to those of the control groups(P > 0.05). The activity of the antioxidant enzyme GTx was decreased in the gut of animals subjected to PH compared with that in the control group of animals not subjected to PH(P < 0.01). However, the group that received glutamine for seven days after the PPVL showed similar GTx activity to both the control groups not subjected to PH(P > 0.05). At least 10 random, non-overlapping images of each histological slide with 200 × magnification(44 pixel = 1 μm) were captured. The sum means of all áreas, of each group were calculated. The mean areas of e NOS staining for both of the control groups were similar. The PPVL group showed the largest area of staining for e NOS. The PPVL + G group had the second highest amount of staining, but the mean value was much lower than that of the PPVL group(P < 0.01). For i NOS, the control(SO) and control + G(SO + G) groups showed similar areas of staining. The PPVL group contained the largest area of i NOS staining, followed by the PPVL + G group; however, this area was significantly smaller than that of the group that underwent PH without glutamine(P < 0.01).CONCLUSION Treatment with glutamine prevents gut mucosal injury after PH in rats. | Gilmara Pandolfo Zabot Gustavo Franco Carvalhal Norma Possa Marroni Francielli Licks Renata Minuzzo Hartmann Vinícius Duval da Silva Henrique Sarubbi Fillmann | 2017 | World Journal of Gastroenterology2017，23，25： | 3 |
| 4 | Localisation of nitrate in the rhizosphere of biochar-amended soils显示文摘 | Miranda T. Prendergast-Miller Michael Duvall Saran P. Sohi | 2011 | Soil Biology and Biochemistry2011，，11： | 3 |
| 5 | Surgery for Early-Stage Non-Small Cell Lung Cancer: A Systematic Review of the Video-Assisted Thoracoscopic Surgery Versus Thoracotomy Approaches to Lobectomy显示文摘 | Bryan A. Whitson Shawn S. Groth Susan J. Duval Scott J. Swanson Michael A. Maddaus | 2008 | The Annals of Thoracic Surgery2008，，6： | 3 |
| 6 | 丘陵地区面波衰减的两种革新方法显示文摘在地形多变的丘陵地区,地震资料的面波衰减成为一大难题。本文介绍的两种面波衰减革新方法是用不同标准组合方式对有效信号和噪声进行区分的。第1种称双重(视速度和极化)投影滤波,我们以美国南部丘陵地区合成记录证明了其噪声监测能力;第2种是综合利用视速度与不同时间和空间尺度的分解对传统FK滤波方法的改进,我们以加拿大丘陵地区单分量实际地震资料为例进行了说明。 | Laurent Duval 唐祥功 | 2006 | 油气地球物理2006，4，2： | 2 |
| 7 | Effectiveness of a Smoking Cessation Program for Peripheral Artery Disease Patients显示文摘 | Deborah Hennrikus Anne M. Joseph Harry A. Lando Sue Duval Laurie Ukestad Molly Kodl Alan T. Hirsch | 2010 | Journal of the American College of Cardiology2010，，： | 2 |
| 8 | Stent placement versus angioplasty for hepatic artery stenosis after liver transplant: a meta-analysis of case series显示文摘 | Nassir Rostambeigi David Hunter Sue Duval Srinath Chinnakotla Jafar Golzarian | 2013 | European Radiology2013，，5： | 2 |
| 9 | The Role of Matrix Metalloproteinase-7 in Redefining the Gastric Microenvironment in Response to Helicobacter pylori显示文摘 | Catherine McCaig Cedric Duval Elaine Hemers Islay Steele D. Mark Pritchard Sabine Przemeck Rod Dimaline Suhail Ahmed Keith Bodger David D. Kerrigan Timothy C. Wang Graham J. Dockray Andrea Varro | 2006 | Gastroenterology2006，，6： | 2 |
| 10 | 使用体外重建皮肤模型研究真皮成纤维细胞对皮肤色素沉着的重要调节作用:皮肤光老化的影响显示文摘已有大量研究强调了人类角质形成细胞在皮肤色素沉着中所起的作用。例如,角质形成细胞通过释放大量的促色素沉着旁分泌生长因子,如αMSH、内皮素1(ET-1)、干细胞因子(SCF)和多种细胞因子,参与紫外线(UV)急性照射诱导的黑素合成(晒黑)。然而,越来越多的证据显示,真皮内成分在皮肤色素沉着调控中的作用不容忽视。20世纪90年代中期,证实细胞外基质(ECM)可调节黑素细胞的增殖、凋亡抑制和黑素生成活性。有报道证实,真皮成纤维细胞可通过分泌可溶性因子对色素沉着起调控作用。另外,对于构成性肤色,研究发现在掌跖,由成纤维细胞产生的Dikkopf-1(DKK-1)对黑素细胞的生长、活性以及对黑素小体转移均有抑制作用,且认为是这两处身体部位颜色较浅的原因。反之,深肤色皮肤内成纤维细胞分泌的神经调节蛋白1(NGR-1)的促色素沉着效应提示,该特定信号分子在决定高度色素沉着的皮肤类型中发挥作用。此外,在各种先天性色素沉着过度障碍中,如系统性硬皮病、皮肤纤维瘤、多发性神经纤维瘤的咖啡牛奶斑和泛发性进行性色素异常症,已知真皮黑素生成生长因子数量增加;这些因子包括SCF、肝细胞生长因子(HGF)或角质形成细胞生长因子(KGF)。表皮与细胞间质之间紧密的互动也可能在黑素细胞内稳态中发挥作用。最近已证实,层粘连蛋白332可通过调节L酪氨酸摄取来促进黑素生成。生长因子/细胞因子调节环也存在于真皮细胞和表皮细胞之间,并参与色素沉着的调控。 | 陈旭 孔佩慧 Duval C Cohen C Chagnoleau C | 2016 | 中华皮肤科杂志2016，49，10： | 2 |
| 11 | Pression de sublimation du tetrafluoromethane显示文摘 | GENOT B DUVAL X | 1970 | J Chim Physique1970，67，： | 1 |
| 12 | Self-focus, Helping Request Salience, Felt Responsibility, and Helping Behavior 显示文摘 | Mayer F S Duval T S Holtz R Bowman C | 1985 | Personality and Social Psychology Bulletin1985，，11： | 1 |
| 13 | A Hybrid GA/SVM Approach for Gene Selection and Classification of Microarray Data显示文摘 | Huerta E B Duval B Hao J K | 2006 | Lecture Notes in Computer Science2006，3907，： | 1 |
| 14 | A review of faults detectable by gas-in-oil analysis in transformers显示文摘 | DUVAL M | 2002 | IEEE Electrical Insulation Magazine2002，18，3： | 1 |
| 15 | NiO thin film formaldehyde gas sensor显示文摘 | Dirksen J A Duval K Ring T A | 2001 | Sensors and Actuators B2001，80，： | 1 |
| 16 | Development of cryopreservation for oil palm somatic embryos using an improved process显示文摘 | Dumet D Engelmann F Chabrillange N and Duval Y | 1993 | Ol e agineux1993，48，： | 1 |
| 17 | Ten-year incidence and risk factors of bone fractures in a cohort of treated HIV1- infected adults显示文摘 | Collin F Duval X Le MV | 2009 | AIDS2009，23，8： | 1 |
| 18 | A review of faults detectable by gas-in-oil analysis in transformers显示文摘 | DUVAL M | 2002 | Electrical Insulation Magazine2002，18，3： | 1 |
| 19 | Improving the reliability of trans- former gas-in-oil diagnosis显示文摘 | DUVAL M DUKARM J | 2005 | IEEE Electrical Insulation Magazine2005，21，4： | 1 |
| 20 | Ursolic acid induces apoptosis through caspase-3 activation and cell cycle arrest in HaCat cells显示文摘 | Harmand PO Duval R Liagre B etal | 2003 | Int J Oncol2003，23，1： | 1 |
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