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100篇 您的检索式:作者名="DIMITRIOU L"
    题名 作者 年代 出处 被引量
1一种miRNA标记在胶质瘤侵袭性表型的确定与预后评估中的价值(英文)显示文摘Gliomas represent a disparate group of tumours for which there are to date no cure. Thus,there is a recognized need for new diagnostic and therapeutic approaches based on increased understanding of their molecular nature. We performed the comparison of the microRNA( miRNA) profile of 8 WHO grade II gliomas and 24 higher grade tumours( 2 WHO grade III and 22 glioblastomas) by using the Affymetrix Gene Chip miRNA Array v. 1. 0. A relative quantification method( RT-q PCR) with standard curve was used to confirm the 22 miRNA signature resulted by array analysis. The prognostic performances of the confirmed miRNAs were estimated on the Tumor Cancer Genome Atlas( TCGA) datasets. We identified 22 miRNAs distinguishing grade II gliomas from higher grade tumours.RT-q PCR confirmed the differential expression in the two patients' groups for 13 out of the 22 miRNAs. The analysis of the Glioblastoma Multiforme( GBM) and Lower Grade Glioma( LGG) datasets from TCGA demonstrated the association with prognosis for 6 of those miRNAs. Moreover,in the GBM dataset miR-21 and miR-210 were predictors of worse prognosis in both univariable and multivariable Cox regression analyses( HR 1. 19,P = 0. 04,and HR 1. 18,P = 0. 029 respectively). Our results support a direct contribution of miRNAs to glioma cancerogenesis and suggest that miR-21 and miR-210 may play a role in the aggressive clinical behaviour of glioblastomas.Barbano R Palumbo O Pasculli B Galasso M Volinia S D'Angelo V Icolaro N Coco M Dimitri L Graziano P Copetti M Valori VM Maiello E Carella M Fazio VM Parrella P 2014中华神经外科疾病研究杂志2014,13,5:6
2Is There a Possibility of a Cure in Patients With Colorectal Peritoneal Carcinomatosis Amenable to Complete Cytoreductive Surgery and Intraperitoneal Chemotherapy?显示文摘Diane Goéré David Malka Dimitri Tzanis Vinicius Gava Valérie Boige Clarisse Eveno Léon Maggiori Frédéric Dumont Michel Ducreux Dominique Elias 2013Annals of Surgery2013,,6:2
3Solitary fibrous tumor of the central nervous system:report of an additional 5cases with comprehensive literature review显示文摘Bisceglia M Dimitri L Giantempo G 2011Int J Surg Pathol2011,19,4:1
4Investigation of mixing/segregation of mixture particles in gas-solid fluidized beds 显示文摘LU H L ZHAO Y H DING J M DIMITRI G LI W 2007Chemical Engineering Science2007,62,12:1
5The patho physiologic roles of interleukin-6 in human disease 显示文摘Dimitris A Papanicolaou MD Ronald L 1998Ann Intern Med1998,128,:1
6Putting out the fire: coordinated suppression of the innate and adap tire immune systems by SOCS1 and SOCS3 proteins 显示文摘Dimitriou ID Clemenza L Scotter AJ etal 2008Immunol Rev2008,224,:1
7Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis显示文摘Stefan Leucht Andrea Cipriani Loukia Spineli Dimitris Mavridis Deniz ?rey Franziska Richter Myrto Samara Corrado Barbui Rolf R Engel John R Geddes Werner Kissling Marko Paul Stapf Bettina L?ssig Georgia Salanti John M Davis 2013The Lancet2013,,:1
8Storage response of cactus pear fruit following hot water brushing 显示文摘Dimitris L Pompodakis N Markellou E 2005Postharvest Biol Technol2005,38,:1
9Circadian effects on the acute responses of salivary cortisol and IgA in well trained swimmers显示文摘Dimitriou L Sharp NC Doherty M 2002Br J Sports Med2002,36,4:1
10Solitary fibrous tumorof the central nervous system: Report of an additional 5 cases withcomprehensive literature review 显示文摘Bisceglia M Dimitri L Giannatempo G 2011Int J Surg Pathol2011,19,4:1
11Diversity, Activity, and Abundance of Sulfate-Reducing Bacteria in Saline and Hypersaline Soda Lakes显示文摘Mirjam F Dimitry Y S Bait L 2007Appl Environ Microbiol2007,73,7:1
12Endometrioid carcinoma of the fallopian tube resembling a female adnexal tumor of probable wolffian origin显示文摘Fukunaga M Bisceglia M Dimitri L 0,,05:1
13Flatness defects after bridle rolls: a numerical analysis of leveling显示文摘Norman Mathieu Regis Dimitriou Anthony Parrico l 2013International Journal of Mate- rial Forming2013,6,2:1
14Pacing pattern and physiological responses to a 5 -rain maximal exercise bout显示文摘Berg Kris E Kauftman Christopher L Katsavelis Dimitris C etal 2008Journal of Strength and Conditioning Research2008,22,5:1
15Solitary fibrous tumor of the central nervous system : report of an additional 5 cases with comprehensive literature review显示文摘Bisceglia M Dimitri L Giannatempo G 2011Int J Surg Pathol2011,19,4:1
16Surgical treatment of missed Monteggia lesions in children显示文摘Alexandre L?dermann Dimitri Ceroni Yan Lefèvre Vincenzo De Rosa Geraldo De Coulon André Kaelin 2007Journal of Children’s Orthopaedics2007,,4:1
17Inclusion of P-A effect in displacement-based seismic design of steel moment resisting frames 显示文摘Aristidis V Asimakopoulos Dimitris L Karabalis Dimitri E Beskos 2007Earthquake Engineering and Structural Dynamics2007,36,14:1
18Determinants of Olympic fencing performance and implications for strength and conditioning training显示文摘TURNER A JAMES N DIMITRIOU L 2014Journal of Strength and Conditioning Research2014,28,10:1
19Structure and magnetic characterization of trinuclear,mixedvalence manganese acetates显示文摘DIMITRIS P K MARTIN L K MYOUNG S L 1992Inorg Chem1992,31,:1
20Adaptive robust optimization for the security constrained unit commiment problem显示文摘Dimitris B Eugene L Sun Xu Andy 2013IEEE Transaction on Power Systems2013,28,1:1
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