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95篇 您的检索式:作者名="Dimitris B"
    题名 作者 年代 出处 被引量
1一种miRNA标记在胶质瘤侵袭性表型的确定与预后评估中的价值(英文)显示文摘Gliomas represent a disparate group of tumours for which there are to date no cure. Thus,there is a recognized need for new diagnostic and therapeutic approaches based on increased understanding of their molecular nature. We performed the comparison of the microRNA( miRNA) profile of 8 WHO grade II gliomas and 24 higher grade tumours( 2 WHO grade III and 22 glioblastomas) by using the Affymetrix Gene Chip miRNA Array v. 1. 0. A relative quantification method( RT-q PCR) with standard curve was used to confirm the 22 miRNA signature resulted by array analysis. The prognostic performances of the confirmed miRNAs were estimated on the Tumor Cancer Genome Atlas( TCGA) datasets. We identified 22 miRNAs distinguishing grade II gliomas from higher grade tumours.RT-q PCR confirmed the differential expression in the two patients' groups for 13 out of the 22 miRNAs. The analysis of the Glioblastoma Multiforme( GBM) and Lower Grade Glioma( LGG) datasets from TCGA demonstrated the association with prognosis for 6 of those miRNAs. Moreover,in the GBM dataset miR-21 and miR-210 were predictors of worse prognosis in both univariable and multivariable Cox regression analyses( HR 1. 19,P = 0. 04,and HR 1. 18,P = 0. 029 respectively). Our results support a direct contribution of miRNAs to glioma cancerogenesis and suggest that miR-21 and miR-210 may play a role in the aggressive clinical behaviour of glioblastomas.Barbano R Palumbo O Pasculli B Galasso M Volinia S D'Angelo V Icolaro N Coco M Dimitri L Graziano P Copetti M Valori VM Maiello E Carella M Fazio VM Parrella P 2014中华神经外科疾病研究杂志2014,13,5:6
2Sensitivity analysis of a star optical network based on mutually coupled semiconductor lasers显示文摘Michail B Apostolos A Dimitris S 2012Journal of Lightwave Technology2012,30,16:1
3Robust optimization with simulated an- nealing显示文摘Dimitris B Omid N 2010Journal of Global Optimization2010,48,2:1
4Towards a holistic knowledge management model 显示文摘Ioannis E Diakoulakis Nikolaos B Georgopoulos Dimitrious E Koulouriotis Dimitrios M Emiris 2004Journal of Knowledge Management2004,,8:1
5Agricultural Contracts:Data and Research Needs显示文摘Hueth B Ligon E Dimitri C 0,,05:1
6Fitting the Weibull log-linear model to accelerated life-test data 显示文摘Wendai W Dimitri B K 2000IEEE Transactions on Reliability2000,49,2:1
7Analysis of the bubbling effect in synchronized networks with semiconductor laser显示文摘Michail B Apostolos A Dimitris S 2013IEEE Photonics Technology Letters2013,25,9:1
8Comparison of effects of theophylline and caffeine on respiratory function of prematurely born infants 显示文摘Laubscher B Greenough A Dimitriou G 1998Early Hum Dev1998,50,2:1
9Single institution's expe- rience in laparoscopic appendectomy as a suitable therapy for compli- cated appendicitis显示文摘Dimitriou I Reckmann B Nephuth O 2013Langenbecks Arch Surg2013,398,1:1
10Treatment of malunion and nonunion at the site of an ankle fusion with the llizarov apparatus 显示文摘Dimitris K Anil B Herzenberg JE 2005The Journal of Bone and Joint Surgery2005,87,:1
11Treatment of malunion and nonunion at the site of an ankle fusion with the llizarov apparatus 显示文摘Dimitris K Anil B 2005The Journal of Bone and Joint Surgery2005,87,:1
12Structure and composition of sweet sorghum stalk components 显示文摘Evaggeli B Dimitris P K Bernard M 1997Industrial Crops and Products1997,,6:1
13On the encapsulation of numerical-hydraulic models in artificial neural network显示文摘Yonas B Dibike Dimitri Solomatine Michael B Abbott 1999Journal of Hydraulic Research1999,37,2:1
14Fitting the Weibull log-linear model to accelerated life-test data显示文摘Wendai W Dimitri B K 2000IEEE Transactions on Reliability2000,49,2:1
15Fitting the Weibull log-llnear model to accelerated life-test data 显示文摘Wendai W Dimitri B K 2000IEEE Transactions on Reliability2000,49,2:1
16Coating of mesh grafts for prolapse and urinary incontinence repair with autologous plasma: Exploration stage of a surgical innovation显示文摘Dimitri B Hplger G Evangelos G 2014Biomed Res Int2014,,:1
17A new generation of vehicle routing research 显示文摘 David S 1995Survey Expository & Tutorial1995,44,2:1
18Effects of Non-planar Geometries and Volumetric Expansion in the Modeling of Oxidation in Titanium显示文摘Pavlin B Entchev Dimitris C Lagoudas John C Slattery 2001International Jounal of Engineering Science2001,39,:1
19Adaptive robust optimization for the security constrained unit commiment problem显示文摘Dimitris B Eugene L Sun Xu Andy 2013IEEE Transaction on Power Systems2013,28,1:1
20Reactive transport modeling of subaqueous sediment caps and implications for the long-term fate of arsenic, mercury, and methylmercury 显示文摘BRAD A B DIMITRI V SUSANA S 2012Aquatic Geochemistry2012,18,4:1
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