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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | 显示文摘 | Jahan M S Cooke D W Hults W L | 1990 | J Luminesc1990，47，： | 2 |
| 3 | Assessment of management alternatives on a small agricultural watershed 显示文摘 | Mostaghimi S Park S W Cooke R A | 1997 | Water Research1997，31，8： | 1 |
| 4 | Simultaneous axial and rotational electron beam velocity measurement using a phosphor scintillator显示文摘 | He W Cooke S J Cross A W | 2001 | Review of Scientific Instruments2001，72，5： | 1 |
| 5 | The Effect of time Delay and Growth Rate Inhibition in the Bacterial Treatment of Wastewater显示文摘 | Bush A W Cook S E | 1975 | J Thoo- ret Biol1975，63，： | 1 |
| 6 | Canine distemper terminal and intergenic non-protein coding nucleotide sequences:completion of the entire CDV genome sequences显示文摘 | Sidhu M S Husar W Cook S D | 1993 | Virology1993，193，1： | 1 |
| 7 | An autosomal genome scan for loci influencing the longitudinal burden of body mass index from childhood to young adulthood in white sibships: the Bogalusa Heart Study显示文摘 | Chen W Li S Cook NR | 2004 | Int J Obes Relat Metab Disord2004，28，： | 1 |
| 8 | Curly bare (cub) ,a new mouse mutation on chromosome 11 cau- sing skin and hair abnormalities, and a modifies gene( mcub) on chromosome 5 显示文摘 | Johnson K R Lane P W Cook S A | 2003 | Genomics2003，81，1： | 1 |
| 9 | Thermally stimulated luminescence from commonly occurring impurity phases in high-temperature superconductors显示文摘 | Jahan M S Cooke D W Huhs W L | 1990 | J Lumin1990，47，3： | 1 |
| 10 | Minimum shear reinforcement in normal, medium, and high-strength concrete beams显示文摘 | Yoon Y S Cook W D Mitchell D | 1996 | ACI Structural Journal1996，93，5： | 1 |
| 11 | The Synthesis of 4-Nitro-,5-Nitro-,6-Nitro-and 7-Nitroindole显示文摘 | Parmerter S M Cook G A Dixon W B | 1958 | Journal of the American Chemical Society1958，80，： | 1 |
| 12 | DNA marker analysis detects multiple maternity and paternity in single brood of the lesser snow goose 显示文摘 | Quinn T W Quinn J S Cooke F | 1987 | Nature1987，326，： | 1 |
| 13 | Irrigation and land use drive ground ar-thropod community palterns in urban desert 显示文摘 | Cook W M Faeth S H | 2006 | Environmental Entomology2006，35，： | 1 |
| 14 | Xenon purity analysis for exo-200 via mass spectrometry 显示文摘 | Dobi A Hall C Slutsky S Yen Y R Aharmin B Auger M Barbeau P S Benitez-Medina C Breidenbach M Cleveland B Conley R Cook J Cook S Counts I Craddock W Daniels T Davis C G Davis J Devoe R Dixit M Dolinski M J Donato K Fairbank Jr W Farine J Fierlinger P Franco D Giroux G Gornea R Graham K Gratta G Green C Hagemann C Hall K Hallman D Hargrove C Herrin S Hughes M Hodgson J Juget F Karelin A Kaufman L J Kuchenkov A Kumar K Leonard D S Lutter G Mackay D Maclellan R Marino M Mong B Montero Diez M Morgan P MUller A R Neilson R Odian A Oullivan K Piepke A Pocar A Prescott C Y Pushkin K Rivas A Rollin E Rowson P C Sabourov A Sinclair D Skarpaas K Stekhanov V Strickland V Swift M Twelker K Vuilleumier J L Vuilleumier J M Weber M Wichoski U Wodin J Wright J D Yang L | 2012 | Nuclear Instruments and Methods in Physics Research Section A: Accelerators Spectrometers Detectors and Associated Equipment2012，675，： | 1 |
| 15 | Canine distemper terminal and intergenic non- protein coding nucleotide sequences: completion of the entire CDV genome sequence显示文摘 | Sidhu M S Husar W Cook S D | 1993 | Virology1993，193，1： | 1 |
| 16 | Linking plant tissue concentrations and soil copper pools in urban contaminated soils显示文摘 | SAUVE S COOK N HENDERSHOT W H | 1996 | Environmental Pollution1996，94，2： | 1 |
| 17 | Evaluation of alkaline phosphatase- and digoxigenin-labeled probes for detection of the thermolabile hemolysin (tlh) gene of Vibrio parahaemolyticus 显示文摘 | McCarthy S A DePaola A Cook D W Kaysner C A and Hill W E | 1999 | Letters in Applied Microbiology1999，28，： | 1 |
| 18 | Defect in peroxisome prol- iferator-activated receptor-inducible fatty acid oxidation deter- mines the severity of hepatic steatosis in responseto fasting显示文摘 | Hashimoto T Cook W S Qi C | 2000 | J Biol Chem2000，275，28： | 1 |
| 19 | Performance of sand-domina ted golf greens in relation to rootzone characteristics 显示文摘 | Baker S W Binns D J Cook A | 1997 | Journal of Turfgrass Science1997，73，1： | 1 |
| 20 | Selective ring opening of naphthenic molecules显示文摘 | McVicker G B Daage M Touvelle M S Hudson C W Klein D P Baird W C Cook B R Chen J G Hantzer S Vaughan D E W Ellis E S Feeley O C | | 0，，01： | 1 |
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