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| 1 | FSH dosage effect on conventional sperm parameters:a meta-analysis of randomized controlled studies显示文摘Follicle-stimulating hormone(FSH)represents a therapeutic option in normogonadotropic patients with idiopathic oligozoospermia.The aim of this review was to evaluate the possible dose-and drug-dependent efficacy of FSH treatment on conventional sperm parameters.We performed a comprehensive systematic review via a meta-analysis of all available randomized controlled trials,in which FSH administration was compared with placebo or no treatment when administered to normogonadotropic patients with idiopathic oligozoospermia.Of the 971 articles that were retrieved,5 were fin ally included,in eluding a total of 372 patie nts and 294 controls.Overall,FSH treatment was effective in ameliorating the sperm concentration,total count,progressive motility,but not normal forms.On the basis of the weekly dosage,the studies were classified into those using low(175-262.5 IU per week),intermediate(350-525 IU per week),and high(700-1050 IU per week)doses.At low doses,FSH improved only sperm motility.At intermediate doses,FSH ameliorated sperm concentration and morphology.Total sperm count and progressive motility showed a trend toward the increase.At high doses,FSH increased sperm concentration,total sperm count,and progressive motility.Sperm morphology showed a trend toward the increase.Finally,both highly purified FSH(hpFSH)and recombinant human FSH(rhFSH)improved sperm concentration,total sperm count,progressive motility,but not morphology.No different efficacy was observed between these two preparations.This meta-analysis provides evidence in favor of high FSH doses.The FSH efficacy was not related to the preparation type(recombinant vs highly purified).Further studies are needed to evaluate the effectiveness of Iong-standing treatment regimes. | Rossella Cannarella Sandro La Vignera Rosita A Condorelli Laura M Mongioi Aldo E Calogero | 2020 | Asian Journal of Andrology2020，22，3： | 2 |
| 2 | The beneficial effects of antioxidant supplementation in enteral feeding in critically ill patients:a prospective,randomized,double-blind,placebo-controlled trial显示文摘 | Crimi E Liguori A Condorelli M | 2004 | Anesth Analg2004，99，： | 1 |
| 3 | PED/PEA-15:an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis显示文摘 | Condorelli G Vigliotta G Cafieri A Trencia A AndalòP Oriente F Miele C Caruso M Formisano P Beguinot F | 1999 | Oncogene1999，18，31： | 1 |
| 4 | Metal- organic chemical vapor deposition of ferroelectric SrBi2Ta2O9 films from a fluorine-containing precursor system显示文摘 | CONDORELLI G G FAVAZZA M BEDOYA C | 2006 | Chem Mater2006，18，4： | 1 |
| 5 | Glycoxidation of low-density lipoprotein increase Tunel positivity and CPP32 activation in human coronary cells显示文摘 | Nigris F Tajana G Condorelli M | 2003 | Ann N Y Acad Sci2003，1010，： | 1 |
| 6 | Haemostatic balance in patients with acute focal cerebral vaseulopathy显示文摘 | Ferlito S Condorelli M Mazzone D | 1994 | Panminerva Med1994，36，4： | 1 |
| 7 | MicroRNA control of podosome formation in vascular smooth musclecells in vivo and in vitro 显示文摘 | Quintavalle M Elia L Condorelli G | 2010 | J Cell Biol2010，189，1： | 1 |
| 8 | nfieroRNAs in heart disease: putative novel therapeutic targets显示文摘 | Condorelli G Latronico M V Dorn G W | 2010 | Eur Heart J2010，31，： | 1 |
| 9 | MicroRNAs as regulators of death receptors signaling显示文摘 | Garofalo M Condorelli GL Croce CM | | 0，，02： | 1 |
| 10 | Increased recovery systolic pressure after upright bicycle exercise : its incidence and usefulness for dectecting coronary artery disease 显示文摘 | Romano M Condorelli M | 1988 | Am J Nonivas cardiol1988，2，： | 1 |
| 11 | miR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation显示文摘 | Michela Garofalo Gianpiero Di Leva Giulia Romano Gerard Nuovo Sung-Suk Suh Apollinaire Ngankeu Cristian Taccioli Flavia Pichiorri Hansjuerg Alder Paola Secchiero Pierluigi Gasparini Arianna Gonelli Stefan Costinean Mario Acunzo Gerolama Condorelli Carlo M | 2009 | Cancer Cell2009，，6： | 1 |
| 12 | miR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation显示文摘 | Michela Garofalo Gianpiero Di Leva Giulia Romano Gerard Nuovo Sung-Suk Suh Apollinaire Ngankeu Cristian Taccioli Flavia Pichiorri Hansjuerg Alder Paola Secchiero Pierluigi Gasparini Arianna Gonelli Stefan Costinean Mario Acunzo Gerolama Condorelli Carlo M | 2009 | Cancer Cell2009，，6： | 1 |
| 13 | Circulating levels of cytokines and their site of production in patients with mild to severe chronic heart failure显示文摘 | Pettetta M Condorelli GL Spinelli L | 2000 | Am Heart J2000，140，： | 1 |
| 14 | MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice显示文摘 | Zhang D Contu R Latronico M.V Zhang J Rizzi R Catalucci D Miyamoto S Huang K Ceci M Gu Y Dalton N.D Peterson K.L Guan K.L Brown J.H Chen J Sonenberg N Condorelli G | | 0，，： | 1 |
| 15 | MicroRNA and cardiac pathologies 显示文摘 | LATRONICO M V CATALUCCI D CONDORELLI G | 2008 | Physiol Genom- ics2008，34，3： | 1 |
| 16 | MicroRNAs in diseases and drug response显示文摘 | Garofalo M Condorelli G Croce CM | | 0，，： | 1 |
| 17 | IPO-V2: a prospective, muhicenter, randomized, comparative clinical inves- tigation of the effects of sulodexide in preventing cardiovascular ac- cidents in the first year after acute myocardial infarction 显示文摘 | Condorelli M hiariello M aggianti A | 1994 | Am Coil Cardiol1994，23，： | 1 |
| 18 | Mi- croRNAs as regulators of death receptors signaling 显示文摘 | GAROFALO M CONDORELLI G L CROCE C M | 2009 | Cell Death Differ2009，17，2： | 1 |
| 19 | Effect of coenzyme QlO therapy in patients with congestive heart failure: a long-term multicenter randomized study显示文摘 | MORISCO C TRIMARCO B CONDORELLI M | 1993 | Clin Investig1993，71，8： | 1 |
| 20 | MicroRNAs in diseases and drug respones显示文摘 | Garofalo M Condorelli G Croce CM | 2008 | Curt Opin Pharmaco12008，8，5： | 1 |
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