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| 1 | Magmatic Event at the End of the Archean in Eastern Hebei Province and Its Geological Implication显示文摘By using the SHRIMP U-Pb and single zircon stepwise evaporation methods, the authors have obtained some results for granitoids from eastern Hebei Province. The Yuhuzhai hyperthene tonalitic granite was formed 2550 Ma ago, the Qingyangshu gabbroic gneiss 2536 Ma, the Yinmahe granodioritic gneiss near Lücao, Lulong County, 2533 Ma, the gabbro-dioritic gneiss near Longwan, Qianxi County, 2518?2515 Ma, the Qiuhuayu trondjemitic gneiss at Zunhua 2515 Ma, the Xiaoguanzhuang tonalitic gneiss at Zunhua 2495 Ma, and the Cuizhangzi gneiss in Qianxi County 2492 Ma. These geochronilogical data demonstrate that, though diverse in composition, type and origin, the granitic gneisses in eastern Hebei Province were emplaced and crystallized in a rather short period of magmatic activity. The formation of such a great amount of gneisses in this small time gap suggests that it was a critical crust accretion stage at the end of Neoarchean. The fact that granitoids of various types occurred at the same time implies a large-scale underplating (mantle plume) activity, which was then responsible for the crust accretion. | GENG Yuansheng LIU Fulai YANG Chonghui | 2006 | Acta Geologica Sinica(English Edition)2006，80，6： | 87 |
| 2 | The age of the base of the Paleoproterozoic Hutuo Group in the Wutai Mountains area, North China Craton: SHRIMP zircon U-Pb dating of basaltic andesite显示文摘Basalt and basaltic andesite metamorphosed at greenschist facies occurs with conglomerate layers at the bottom of the Paleoproterozoic Hutuo Group in the Wutai Mountains area, North China Craton. Detailed geological surveying confirms that these volcanic rocks are conformable within the neighboring sedimentary rocks. The SHRIMP results on basaltic andesite are divided into two groups. In one group the 207Pb/206Pb ages are from 2433 to 2558 Ma, which is consistent with the basement crustal age in Fuping and Wutai areas. In the other group, 13 grains yielded a weighted mean 207Pb/206Pb age of 2140±14 Ma. The latter is interpreted as the eruption age of the basaltic andesite, and gives the age of the base of the Hutuo Group. This result further suggests that the Hutuo Group formed in the middle Paleoproterozoic, not the early Palaeoproterozoic or late Archaean, as thought before, and is related to a 2.2-2.1 Ga rifting event in the Central North China Craton. | DU LiLin YANG ChongHui GUO JingHui WANG Wei REN LiuDong WAN YuSheng GENG YuanSheng | 2010 | Chinese Science Bulletin2010，55，17： | 43 |
| 3 | Formation ages and source regions of the Palaeoproterozoic Gaofan, Hutuo and Dongjiao groups in the Wutai and Dongjiao areas of the North China Craton from SHRIMP U-Pb dating of detrital zircons: Resolution of debates over their stratigraphic relationships显示文摘这份报纸在北方中国 Craton 的 Wutai 和 Dongjiao 区域报导 Gaofan, Hutuo 和 Dongjiao 组的元沉积的岩石的由岩屑形成的锆石年龄分布。由岩屑形成的锆石一从 Gaofan 组的 quartzite 主要是在年龄的 2.5 Ga,与大约 2.7 Ga 并且更旧。A 石英岩从 Hutuo 组的基础集团企业的卵石在到 Gaofan 组的 quartzite 的由岩屑形成的锆石年龄分发是类似的。为从 Dongjiao 组的 meta-feldspar-quartz 沙岩,由岩屑形成的锆石的年龄主要在 2.5 Ga 被集中。比 2.6 Ga 旧的锆石都没被识别,但是在年龄与一些是 1.84 Ga 和 2.22.0 Ga。与更早的研究结合了,下列结论能被得出:(1 ) Gaofan 组是在年龄的早 Palaeoproterozoic 并且对迟了的 Neoarchaean Wutai 花岗石绿岩岩层年轻得多、无关,它 unconformably 躺它。因此, Gaofan 组是在诺思中国 Craton 的最旧的 Palaeoproterozoic 元沉积的单位之一。(2 ) Hutuo 组在一个大陆人地下室上在中间的 Palaeoproterozoic (2.14-2.09 Ga ) 被扔,在早 Palaeoproterozoic Gaofan 组后面。(3 ) Dongjiao 组在 1.84 Ga 以后被形成,并且可能属于 Changcheng 系统的更低的部分。(4 ) 从所有三个组的由岩屑形成的锆石显示出 2.5 Ga 的一座明显的年龄山峰,从在北方中国 Craton 在太古代的结束在强烈 tectono-magma-thermal 事件形成的火的岩石被采购。 | WAN YuSheng MIAO PeiSheng LIU DunYi YANG ChongHui WANG Wei WANG HuiChu WANG ZheJiu DONG ChunYan DU LiLin ZHOU HongYing | 2010 | Chinese Science Bulletin2010，55，13： | 32 |
| 4 | Formation age and tectonic environment of the Gantaohe Group,North China Craton:Geology,geochemistry,SHRIMP zircon geochronology and Hf-Nd isotopic systematics显示文摘The Gantaohe Group is an important early Precambrian unit in the Trans-North China Orogen,North China Craton,and is mainly composed of greenschist-facies metabasalt,meta-sandstone and dolomitic marble.We report whole-rock geochemical compositions and SHRIMP zircon ages as well as LA-ICP-MS Hf-in-zircon isotopeic analyses for metabasalts from the Gantaohe Group.SHRIMP dating yielded a weighted mean 207Pb/206Pb age of 2087±16 Ma(MSWD=1.3) for magmatic zircons,but there are also abundant ca.2.5 Ga inherited zircon xenocrysts.The magmatic zircons shows a large Hf(t) variation in Hf(t) from 7.17 to +0.45,suggesting an isotopically highly heterogeneous source for the metabasalt.Chemically all samples show no distinct Zr or Hf anomalies,and some samples show no Nd or Ta anomalies in a primitive mantle-normalized trace element variation diagram,and their whole-rock Nd(t) values range from 4.0 to 0.8.We suggest that the basalt is formed by partial melting of a depleted mantle source,followed by significant crustal contamination.Field observations,the presence of abundant inherited zircon,as well as isotope and trace elements geochemistry support formation of the Gantaohe Group on top of a continental basement.These data and the regional geology lead us to conclude that the Trans-North China Orogen constituted an intracontinental rift during the Paleoproterozoic that was connected to the Eastern Block since the end of the Archean. | XIE HangQiang LIU DunYi YIN XiaoYan ZHOU HongYing YANG ChongHui DU LiLin WAN YuSheng | 2012 | Chinese Science Bulletin2012，57，36： | 16 |
| 5 | Xa1 Allelic R Genes Activate Rice Blight Resistance Suppressed by Interfering TAL Effectors显示文摘Xanthomonas oryzae pathovar oryzae(Xoo)uses transcription activator-like effectors(TALEs)to cause bacterial blight(BB)in rice.In turn,rice has evolved several mechanisms to resist BB by targeting TALEs.One mechanism involves the nucleotide-binding leucine-rich repeat(NLR)resistance gene Xa1 and TALEs.Reciprocally,Xoo has evolved TALE variants,C-terminally truncated versions(interfering TALEs or iTALEs),to overcome Xa1 resistance.However,it remains unknown to what extent the two co-adaptive mechanisms mediate Xoo–rice interactions.In this study,we cloned and characterized five additional Xa1 allelic R genes,Xa2,Xa31(t),Xa14,CGS-Xo111,and Xa45(t)from a collection of rice accessions.Sequence analysis revealed that Xa2 and Xa31(t)from different rice cultivars are identical.These genes and their predicted proteins were found to be highly conserved,forming a group of Xa1 alleles.The XA1 alleles could be distinguished by the number of C-terminal tandemrepeats consisting of 93 amino acid residues and ranged from four in XA14 to seven in XA45(t).Xa1 allelic genes were identified in the 3000 rice genomes surveyed.On the other hand,iTALEs could suppress the resistance mediated by Xa1 allelic R genes,and iTALE genes were prevalent(95%)in Asian,but not in African Xoo strains.Our findings demonstrate the prominence of a defense mechanism in which rice depends on Xa1 alleles and a counteracting mechanismin which Xoo relies on iTALEs for BB. | Chonghui Ji Zhiyuan Ji Bo Liu He Cheng Hua Liu Sanzhen Liu Bing Yang Gongyou Chen | 2020 | Plant Communications2020，1，4： | 14 |
| 6 | Provenance of the Paleoproterozoic Hutuo Group basal conglomerates and Neoarchean crustal growth in the Wutai Mountains,North China Craton:Evidence from granite and quartzite pebble zircon U-Pb ages and Hf isotopes显示文摘Zircon U-Pb ages(SHRIMP and LA-ICPMS) and Lu-Hf isotope data(LA-ICPMS) are presented for two granite and two quartzite pebbles from the basal conglomerates of the Sijizhuang Formation in the Hutuo Group from the Wutai Mountains area in the North China Craton.These two granite pebbles give zircon 207 Pb/206 Pb ages of 2513±8 Ma and 2527±8 Ma respectively,which are consistent with the emplacement ages of the Wangjiahui grey granite and Guangmingsi or Shifo granite in the Wutai Mountains.Detrital zircons from those two quartzite pebbles are mostly 2550-2490 Ma old with lesser number of 2800-2550 Ma grains,which is similar to the ages of detrital zircons from quartzites in the Gaofan Subgroup of the Neoarchean Wutai Group.Thus,the pebbles in the Hutuo Group basal conglomerates were derived locally from Wutai Mountains Neoarchean sources.Zircons from the Sijizhuang Formation conglomerate granite and quartzite pebbles mostly have positive ε Hf(t) values,a minority with ε Hf(t) values like model depleted mantle(DM) of the same age,but with most showing DM model ages 200-100 Ma.This indicates that most of the source materials were derived from the mantle within the previous 200 million years,whereas some are derived from 2550-2510 Ma juvenile crustal additions.This additional evidence suggests that in the North China Craton there was important initial polycyclic crustal formation and cratonization in the late Neoarchaean,prior to superimposed Palaeoproterozoic orogenic cycles. | DU LiLin YANG ChongHui WANG Wei REN LiuDong WAN YuSheng SONG HuiXia GAO LinZhi GENG YuanSheng HOU KeJun | 2012 | Science China Earth Sciences2012，55，11： | 8 |
| 7 | Metamorphism of the East Sector of the Southern Qinling Orogenic Belt and Its Geological Significance显示文摘The east sector of the southern Qinling belt is, lithologically, composed mainly of metapelites,quartzites, marbles and small amount of metabasites and gneisses, whose protoliths are the Silurian, Devonian andless commonly the Sinian and Upper Palaeozoic. They have been subjected at least to two epochs of metamorphism.The early epoch belongs to progressive metamorphism which is centered on high amphibolite-granulite facies in theFuping area and changed outwards into low amphibolite facies (staurolite-kyanite zone), epidote amphibolite facies(garnet zone) and greenschist facies (chlorite and biotite zones), the metamorphic age of which is about 220-260 Ma.This early-epoch metamorphism belongs to different pressure types: the rocks from greenschist to low amphibolitefacies belong to the typical medium-pressure type which shows geothermal gradients of about 17-20℃/km and wasprobably produced by a crustal thickening process related to continental collision, and the high amphibolite-granulitefacies belongs to the low-pressure type which shows geothermal gradients of about 25-38℃/km and was probablyaffected by some magmatic heats. Based on the basic characteristics of the P-T paths of the different facies calculatedfrom the garnet zonations, it can be deduced that the metamorphism of medium-pressure facies series took place dur-ing an imbricated thickening process, rather than during the uplifting process after thickening. The late-epoch meta-morphism belongs to dynamic metamorphism of greenschist facies which is overprinted on the early-epoch meta-morphic rocks and is Yanshanian or Himalayan in age, probably related to intracontinental orogeny. | WEI Chunjing YANG Chonghui ZHANG Shouguang | 1999 | Acta Geologica Sinica(English Edition)1999，73，1： | 7 |
| 8 | AaMYB3 interacts with AabHLH1 to regulate proanthocyanidin accumulation in Anthurium andraeanum(Hort.)—another strategy to modulate pigmentation显示文摘Proanthocyanidins(PAs),also known as“condensed tannins”,are colorless metabolites produced through the flavonoid pathway that are involved in stress resistance in plants.Because PAs are involved in the anthocyanin biosynthetic pathway,they play a role in the modification of pigmentation conferred by anthocyanins in ornamental organs.In this study,we isolated the gene and functionally characterized an R2R3-MYB transcription factor(TF),AaMYB3,and a basic helix-loop-helix TF,AabHLH1,from Anthurium andraeanum(Hort.),a typical tropical flower.AaMYB3 is primarily expressed in the spathe and negatively correlates with anthocyanin accumulation.A complementation test in an Arabidopsis tt8 mutant showed that AabHLH1 successfully restores the PA-deficient seed coat phenotype.The ectopic overexpression of AaMYB3 alone or its coexpression with AabHLH1 in transgenic tobacco resulted in light pink or even pale-pink corolla limbs by reducing their anthocyanin levels and greatly enhancing their accumulation of PAs.This overexpression of the anthurium TF genes upregulated the late anthocyanin enzymeencoding genes(NtDFR and NtANS)and the key PA genes(NtLAR and NtANR)in transgenic tobacco.The interaction between AaMYB3 and the AabHLH1 protein was confirmed using yeast two-hybrid(Y2H)and bimolecular fluorescence complementation(BiFC)assays.In the developing red spathes of the cultivars“Vitara”and“Tropical”,the expression of AaMYB3 was closely linked to PA accumulation,and AaMYB3 was coexpressed with AaCHS,AaF3H,AaDFR,AaANS,AaLAR,and AaANR.The expression pattern of AabHLH1 was similar to that of AaF3′H.Our results suggest that AaMYB3 and AabHLH1 are involved in the regulation of PA biosynthesis in anthurium and could potentially be used to metabolically engineer PA biosynthesis in plants. | Chonghui Li Jian Qiu Surong Huang Junmei Yin Guangsui Yang | 2019 | Horticulture Research2019，6，1： | 6 |
| 9 | Discovery of granulite from the Fuping area in southern Qinling Mountains and its geological significance显示文摘Two-pyroxene-bearing granulites were discovered for the first time in the Hercynian-Indosinian metamorphic belt of the southern Qinling Mountains. The granulites occur in the lower part of the Fuping complex and are dominated by intermediate-acidic rocks intercalated with a small amount of bands and lenses of basic granulites. The main metamorphic minerals include orthopyroxene, clinopyroxene, biotite, plagioclase and quartz, and orthopyroxenes are often retrogressively transformed into amphiboles. The metamorphic conditions have been estimated to be %T%=720-780℃ and %P%=0.6 GPa. The granulite-bearing Fuping complex probably belongs to early Proterozoic in age. Whether it occurs as the crystalline basement of the southern Qinling Hercynian-Indosinian orogenic belt or as a thrusted slice in the collisional process needs further study. | Chunjing Wei Chonghui Yang Shouguang Zhang Rongshe Li | 1998 | Chinese Science Bulletin1998，43，16： | 6 |
| 10 | Industrial Poverty Alleviation Model in Southwestern High-altitude Mountainous Areas of China——A Case Study of Industrial Poverty Alleviation of Xueshan Township in Luquan County of Yunnan Province through Planting Codonopsis pilosula显示文摘Due to the severe restrictions of natural conditions and ecological environment,high-altitude mountainous areas usually become the ' hard bones' in the battle against poverty. Xueshan Township,Luquan Yi and Miao Autonomous County of Yunnan Province,located in the alpine valley of Jinsha River,is a major township with wide and deep poverty,and the incidence of poverty is up to 45. 00%. In recent years,Xueshan Township has insisted on the battle against poverty,made effort to develop the Codonopsis pilosula industry,and successfully developed a road to poverty alleviation through C. pilosula industry,and formed a unique industrial poverty alleviation model by the end of 2018,the incidence of poverty dropped to 0. 74%. Based on field survey and interview,this paper analyzes and summarizes the specific practices,main results,practical experience and promotion and application measures of the poverty alleviation model of C. pilosula planting industry in Xueshan Township,in the hope of providing certain reference for the targeted poverty alleviation in similar areas in Yunnan Province and other provinces of China. | Zisheng YANG Renyi YANG Yanbo HE Chonghui LU En ZHU Yaohan PI Mingxin WU Ying XIONG | 2019 | Asian Agricultural Research2019，11，3： | 4 |
| 11 | Petrological Implication of the Albite Rims in the Felsic Gneisses of the Fuping Complex显示文摘The albite rim is present in most felsic gneisses of the Fuping Complex.The presence of the rim indicates the coexistence of plagioclase and K-feldspar in the rock.The rim is formed immediately after the myrmekite,and both textures were derived from the alteration of K-feldspar.The difference is that that there is no quartz present in the rim,and the rim is nearly albite and the anorthite content of the rim plagioclase is substantially lower than that of the myrmekite plagioclase.Formed at 400-500°C the albite rim was derived from the K-feldspar composition adjustment in the late or post-magmatism stage.As the temperature decreased,the equilibrium between K-feldspar and plagioclase could be maintained,and reactions between the minerals occurred.The leucocratic veins in the complex show distinguished magma or migmatitic characteristics.The rim might form in the late magma or deuteric stage.The formation of the rim implies obvious granitic magma-or melt-injection activity.Typical metamorphic rocks cannot produce the rims.Anatexis after medium-high grade metamorphism might be subordinate.If present,the anatexis is water-present,but the rim texture cannot be taken as the symbol of anatexis. | REN Liudong YANG Chonghui DULilin | 2012 | Acta Geologica Sinica(English Edition)2012，86，2： | 4 |
| 12 | Circulating miR-17-5p and miR-20a: Molecular markers for gastric cancer显示文摘 | Mei Wang Hongbing Gu Sheng Wang Hui Qian Wei Zhu Ling Zhang Chonghui Zhao Yang Tao Wenrong Xu | 2012 | Molecular Medicine Reports2012，，6： | 3 |
| 13 | Discovery of Eoarchean Meta-Dioritic Rocks in Anshan Area, China and Its Geological Significance显示文摘In the Anshan area of Liaoning Province, an occurrence area of the oldest rocks in the world,the meta-dioritic rock of Eoarchaean has recently been found as enclaves in the 3. 8 Ga Dongshan banded trondhjemitic rock. It has relatively high contents of REE (w(∑REE) = 149. 3×10-6) and unmarked LREE enrichment over HREE (wn (La)/wa (Yb) = 6. 99). Eight analysed zircon grains yield a well-defined discordia with an upper intercept of 3. 65 Ga. Some of the data points give an important in formation of more ancient zircon existence in the rock. The rock shows unusually low ε(Nd, 3. 8 Ga) values of - 1. 15 to -1. 24 and large tDM age of 4. 15-4.16 Ga. The geological significance of the discovery is briefly discussed in this paper. | Wan Yusheng Liu Dunyi Li Huiming Yang Chonghui(Institute of Geology, Chinese Academy of Geological Sciences, Beijing 100037) | 1999 | Journal of Earth Science1999，18，4： | 3 |
| 14 | Host HDAC4 regulates the antiviral response by inhibiting the phosphorylation of IRF3显示文摘Class II HDACs, such as HDAC4, are critical regulators of the immune response in various immune cells;however, its role in innate immunity remains largely unknown.Here, we report that the overexpression of HDAC4 suppresses the production of type I interferons triggered by pattern-recognition receptors (PRRs). HDAC4 repressed the translocation of transcription factor IRF3 to the nucleus, thereby decreasing IRF3-mediated IFN-β expression. In particular, we also determined that HDAC4 can be phosphorylated and simultaneously block the phosphorylation of IRF3 at Ser386 and Ser396 by TBK1 and IKKε, respectively, by interacting with the kinase domain of TBK1 and IKKε. Furthermore, IFN-β may stimulate the expression of HDAC4. Our findings suggest that HDAC4 acts as a regulator of PRR signaling and is a novel mechanism of negative feedback regulation for preventing an overreactive innate immune response. | Qi Yang Jielin Tang Rongjuan Pei XiaoXiao Gao Jing Guo Chonghui Xu Yun Wang QianWang Chunchen Wu Yuan Zhou Xue Hu He Zhao Yanyi Wang Xinwen Chen Jizheng Chen | 2019 | Journal of Molecular Cell Biology2019，11，2： | 2 |
| 15 | Histone Deacetylase 3 Inhibitor Suppresses Hepatitis C Virus Replication by Regulating Apo-A1 and LEAP-1 Expression显示文摘Histone deacetylase (HDAC) inhibitors show clinical promise for the treatment of cancers, including hepatocellular carcinoma (HCC). In this study, we investigated the effect of HDAC inhibitor treatment on hepatitis C virus (HCV)replication in Huh7 human liver cells and in a mouse model of HCV infection. Viral replication was markedly suppressed by the HDAC3 inhibitor at concentrations below 1 mmol/L, with no cellular toxicity. This was accompanied by upregulation of liver-expressed antimicrobial peptide 1 (LEAP-1) and downregulation of apolipoprotein-A1 (Apo-A1), as determined by microarray and quantitative RT-PCR analyses. Moreover, HDAC3 was found to modulate the binding of CCAAT-enhancer-binding protein a (C/EBPa), hypoxia-inducible factor 1 a (HIF1 a), and signal transducer and activator of transcription 3 (STAT3) to the LEAP-1 promoter. HDAC3 inhibitor treatment also blocked HCV replication in a mouse model of HCV infection. These results indicate that epigenetic therapy with HDAC3 inhibitor may be a potential treatment for diseases associated with HCV infection such as HCC. | Yuan Zhou Qian Wang Qi Yang Jielin Tang Chonghui Xu Dongwei Gai Xinwen Chen Jizheng Chen | 2018 | Virologica Sinica2018，33，5： | 2 |
| 16 | The Mode of Promoting Industrial Targeted Poverty Alleviation through Land Circulation in Western Mountainous Region of China——A Case Study of Luquan Yi and Miao Autonomous County in Yunnan Province显示文摘In the industrial targeted poverty alleviation,land circulation is a key process. Based on the national strategy of targeted poverty alleviation,this paper combined the industrial development of targeted poverty alleviation with land circulation. According to the field survey on the current situation of land circulation and promotion of the industrial poverty alleviation in the typical project area of Zhongping Village in Zhongping Town and Jiaowuying Village in Jiulong Town in Luquan Yi and Miao Autonomous County in Yunnan Province,located in the high mountain canyon area of Jinsha River in the upper reaches of the Yangtze River in the west of China. This paper summarized and analyzed the organization and operation mechanism,basic practices and main results of the land circulation and promotion of industrial poverty alleviation model in the typical project area of the county. It also summarized the innovation and successful experience of the model,and then came up with measures to further promote the implementation of the model,so as to provide necessary reference for the implementation of land circulation and industrial targeted poverty alleviation for the poverty-stricken counties in Yunnan Province and similar provinces( cities,regions). | Jing LIU Zisheng YANG Ying XIONG Yanbo HE Chonghui LU Yimei HE Renyi YANG | 2019 | Asian Agricultural Research2019，11，2： | 1 |
| 17 | CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression显示文摘 | Brown Rhonda L Reinke Lauren M Damerow Marin S Perez Denise Chodosh Lewis A Yang Jing Cheng Chonghui | 2011 | Journal of Clinical Investigation2011，，3： | 1 |
| 18 | miR-17-5p/20a are important markers for gastric cancer and MDM2 participates in their functional regulation显示文摘 | Mei Wang Hongbing Gu Hui Qian Wei Zhu Chonghui Zhao Xu Zhang Yang Tao Ling Zhang Wenrong Xu | 2012 | European Journal of Cancer2012，，： | 1 |
| 19 | Improved piecewise vector quantized approximation based on normalized time subsequences显示文摘 | Li Hailin Yang Libin Guo Chonghui | 2013 | Measurement2013，46，9： | 1 |
| 20 | Independent component analysis for time-dependent processes using AR source model 显示文摘 | Yumin Yang Chonghui Guo and Zunquan Xia | 2008 | Neural Process Lett2008，27，： | 1 |
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