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| 1 | A Novel Rice bHLH Transcription Factor, DTD, Acts Coordinately with TDR in Controlling Tapetum Function and Pollen Development显示文摘Dear Editor, Male reproductive development is an essential biological process for flowering plants and crucial for crop seed production.Formation of the male reproductive organ,the anther,involves a number of developmental events,including stamen meristem specification,generation of sporogenous cells and their differentiation into microspore mother cells (MMCs),meiosis,microspore (pollen) maturation,and pollination (Ma,2005).The formation of microspores and their development into mature pollen grains require cooperative interactions between gametophytic (microspores) and sporophytic (anther wall) cells,with the innermost cell layer,the tapetum,playing the most crucial role (Ma,2005).Tapetal cells undergo degeneration by programmed cell death (PCD). | Chonghui Ji Heying Li Libin Chen Min Xie Fengping Wang Yuanling Chen Yao-Guang Liu | 2013 | Molecular Plant2013，6，5： | 14 |
| 2 | Changes in biodiversity and ecosystem function during the restoration of a tropical forest in south china显示文摘Tropical forests continue to vanish rapidly,but few long-term studies have ever examined if and how the lost forests can be restored.Based on a 45-year restoration study in south China,we found that a tropical rain forest,once completely destroyed,could not recover naturally without deliberate restoration efforts.We identified two kinds of thresholds that must be overcome with human ameliorative measures before the ecosystem was able to recover.The first threshold was imposed primarily by extreme physical conditions such as exceedingly high surface temperature and impoverished soil,while the second was characterized by a critical level of biodiversity and a landscape context that accommodates dispersal and colonization processes.Our three treatment catchments(un-restored barren land,single-species plantation,and mixed-forest stand)exhibited dramatically different changes in biodiversity and ecosystem functioning over 4 decades.The mixed forest,having the highest level of biodiversity and ecosystem functioning,possesses several major properties of tropical rain forest.These findings may have important implications for the restoration of many severely degraded or lost tropical forest ecosystems. | REN Hai,LI ZhiAn,SHEN WeiJun,YU ZuoYue,PENG ShaoLin,LIAO ChongHui,DING MingMao & WU JianGuo 1 South China Botanical Garden,Chinese Academy of Sciences,Guangzhou 510650,China 2 Institute of Ecology and Evolution,Zhongshan University,Guangzhou 510275,China 3 Guangdong Institute of Entomology,Guangzhou 510275,China 4 School of Life Sciences and Global Institute of Sustainability,Arizona State University,Tempe,AZ 85287,USA | 2007 | Science China(Life Sciences)2007，50，2： | 9 |
| 3 | AaMYB3 interacts with AabHLH1 to regulate proanthocyanidin accumulation in Anthurium andraeanum(Hort.)—another strategy to modulate pigmentation显示文摘Proanthocyanidins(PAs),also known as“condensed tannins”,are colorless metabolites produced through the flavonoid pathway that are involved in stress resistance in plants.Because PAs are involved in the anthocyanin biosynthetic pathway,they play a role in the modification of pigmentation conferred by anthocyanins in ornamental organs.In this study,we isolated the gene and functionally characterized an R2R3-MYB transcription factor(TF),AaMYB3,and a basic helix-loop-helix TF,AabHLH1,from Anthurium andraeanum(Hort.),a typical tropical flower.AaMYB3 is primarily expressed in the spathe and negatively correlates with anthocyanin accumulation.A complementation test in an Arabidopsis tt8 mutant showed that AabHLH1 successfully restores the PA-deficient seed coat phenotype.The ectopic overexpression of AaMYB3 alone or its coexpression with AabHLH1 in transgenic tobacco resulted in light pink or even pale-pink corolla limbs by reducing their anthocyanin levels and greatly enhancing their accumulation of PAs.This overexpression of the anthurium TF genes upregulated the late anthocyanin enzymeencoding genes(NtDFR and NtANS)and the key PA genes(NtLAR and NtANR)in transgenic tobacco.The interaction between AaMYB3 and the AabHLH1 protein was confirmed using yeast two-hybrid(Y2H)and bimolecular fluorescence complementation(BiFC)assays.In the developing red spathes of the cultivars“Vitara”and“Tropical”,the expression of AaMYB3 was closely linked to PA accumulation,and AaMYB3 was coexpressed with AaCHS,AaF3H,AaDFR,AaANS,AaLAR,and AaANR.The expression pattern of AabHLH1 was similar to that of AaF3′H.Our results suggest that AaMYB3 and AabHLH1 are involved in the regulation of PA biosynthesis in anthurium and could potentially be used to metabolically engineer PA biosynthesis in plants. | Chonghui Li Jian Qiu Surong Huang Junmei Yin Guangsui Yang | 2019 | Horticulture Research2019，6，1： | 6 |
| 4 | Discovery of granulite from the Fuping area in southern Qinling Mountains and its geological significance显示文摘Two-pyroxene-bearing granulites were discovered for the first time in the Hercynian-Indosinian metamorphic belt of the southern Qinling Mountains. The granulites occur in the lower part of the Fuping complex and are dominated by intermediate-acidic rocks intercalated with a small amount of bands and lenses of basic granulites. The main metamorphic minerals include orthopyroxene, clinopyroxene, biotite, plagioclase and quartz, and orthopyroxenes are often retrogressively transformed into amphiboles. The metamorphic conditions have been estimated to be %T%=720-780℃ and %P%=0.6 GPa. The granulite-bearing Fuping complex probably belongs to early Proterozoic in age. Whether it occurs as the crystalline basement of the southern Qinling Hercynian-Indosinian orogenic belt or as a thrusted slice in the collisional process needs further study. | Chunjing Wei Chonghui Yang Shouguang Zhang Rongshe Li | 1998 | Chinese Science Bulletin1998，43，16： | 6 |
| 5 | Discovery of Eoarchean Meta-Dioritic Rocks in Anshan Area, China and Its Geological Significance显示文摘In the Anshan area of Liaoning Province, an occurrence area of the oldest rocks in the world,the meta-dioritic rock of Eoarchaean has recently been found as enclaves in the 3. 8 Ga Dongshan banded trondhjemitic rock. It has relatively high contents of REE (w(∑REE) = 149. 3×10-6) and unmarked LREE enrichment over HREE (wn (La)/wa (Yb) = 6. 99). Eight analysed zircon grains yield a well-defined discordia with an upper intercept of 3. 65 Ga. Some of the data points give an important in formation of more ancient zircon existence in the rock. The rock shows unusually low ε(Nd, 3. 8 Ga) values of - 1. 15 to -1. 24 and large tDM age of 4. 15-4.16 Ga. The geological significance of the discovery is briefly discussed in this paper. | Wan Yusheng Liu Dunyi Li Huiming Yang Chonghui(Institute of Geology, Chinese Academy of Geological Sciences, Beijing 100037) | 1999 | Journal of Earth Science1999，18，4： | 3 |
| 6 | Standard pancreatoduodenectomy versus extended pancreatoduodenectomy with modified retroperitoneal nerve resection in patients with pancreatic head cancer:a multicenter randomized controlled trial显示文摘Background:The extent of pancreatoduodenectomy for pancreatic head cancer remains controversial,and more high-level clinical evidence is needed.This study aimed to evaluate the outcome of extended pancreatoduodenectomy(EPD)with retroperitoneal nerve resection in pancreatic head cancer.Methods:This multicenter randomized trial was performed at 6 Chinese highvolume hospitals that enrolled patients between October 3,2012,and September 21,2017.Four hundred patients with stage I or II pancreatic head cancer and without specific pancreatic cancer treatments(preoperative chemotherapy or chemoradiation)within three months were randomly assigned to undergo standard pancreatoduodenectomy(SPD)or EPD,with the latter followed by dissection of additional lymph nodes(LNs),nerves and soft tissues 270◦on the right side surrounding the superior mesenteric artery and celiac axis.The primary endpoint was overall survival(OS)by intention-to-treat(ITT).The secondary endpoints were disease-free survival(DFS),mortality,morbidity,and postoperative pain intensity.Results:TheR1 ratewas slightly lower with EPD(8.46%)thanwith SPD(12.56%).The morbidity and mortality rates were similar between the two groups.The median OS was similar in the EPD and SPD groups by ITT in the whole study cohort(23.0 vs.20.2 months,P=0.100),while the median DFS was superior in the EPD group(16.1 vs.13.2 months,P=0.031).Patients with preoperative CA19–9<200.0 U/mL had significantly improved OS and DFS with EPD(EPD vs.SPD,30.8 vs.20.9 months,P=0.009;23.4 vs.13.5 months,P<0.001).The EPD group exhibited significantly lower locoregional(16.48%vs.35.20%,P<0.001)andmesenteric LNrecurrence rates(3.98%vs.10.06%,P=0.022).The EPD group exhibited less back pain 6 months postoperation than the SPD group.Conclusions:EPD for pancreatic head cancer did not significantly improve OS,but patients with EPD treatment had significantly improved DFS.In the subgroup analysis,improvements in bothOS and DFS in the EPD armwere observed in patients with preoperative CA19–9<200.0 U/mL.EPD could be used as an effective surgical procedure for patients with pancreatic head cancer,especially those with preoperative CA19–9<200.0 U/mL. | Qing Lin Shangyou Zheng Xianjun Yu Meifu Chen Yu Zhou Quanbo Zhou Chonghui Hu Jing Gu Zhongdong Xu LinWang Yimin Liu Qingyu Liu MinWang Guolin Li He Cheng Dongkai Zhou Guodong Liu Zhiqiang Fu Yu Long Yixiong Li Weilin Wang Renyi Qin Zhihua Li Rufu Chen | 2023 | Cancer Communications2023，43，2： | 3 |
| 7 | An improved algorithm for support vector clus-tering based on maximum entropy principle and kernel matrix 显示文摘 | Chonghui Guo Fang Li | 2011 | Ex-pert Systems with Applications2011，7，38： | 1 |
| 8 | Flavonoid composition and antioxidant activity of tree peony(Paeonia section moutan)yellow flowers显示文摘 | Li Chonghui Du Hui Wang Liangsheng | 2009 | Journal of Agricultural and Food Chemistry2009，57，18： | 1 |
| 9 | Flavonoid composition and antioxidant activity of tree peony (Paeonia section moutan) yellow flowers显示文摘 | LI Chonghui DU Hui WANG Liangsheng | 2009 | Journal of agricultural and food chemistry2009，57，18： | 1 |
| 10 | Improved piecewise vector quantized approximation based on normalized time subsequences显示文摘 | Li Hailin Yang Libin Guo Chonghui | 2013 | Measurement2013，46，9： | 1 |
| 11 | Similarity measure based on piecewise linear approximation and derivative dynamic time warping for time series mining显示文摘 | Li Hailin Guo Chonghui Qiu Wangren | 2011 | Expert Systems with Applications2011，38，14： | 1 |
| 12 | Flavonoid composition and antioxidant activity of tree peony (Paeonia section moutan ) yellow flowers 显示文摘 | Li Chonghui Du Hui Wang Liangsheng | 2009 | Journal of Agricultural and Food Chemistry2009，57，18： | 1 |
| 13 | Experimental Study on the Mechanism for the Formation of Sn- bearing Granite in Northern Guangxi显示文摘Experimental results have proved that the Xuefengian Sn-bearing biotite granites were formed by remelting and recrystallization of the Proterozoic metamorphic rocks of the Sibao Group at 500× 105-2000× 105 Pa and 750-570℃ and further testified that the F- and B-bear-ing aqueous solution played an important part in decreasing the formation temperature of the rocks. The results tally with the reality of the field geology. The authors have thus brought to light the mechanism for the formation of the Sn-bearing biotite granites and expounded the significance of their formation in the crust dynamics of South China. | Liang Xiangji, Qiao Li, Wang Fusheng and Yang Chonghui Institute of Geology, Chinese Academy of Geological Sciences, Beijing | 1994 | Acta Geologica Sinica(English Edition)1994，68，2： | 0 |
| 14 | Overcoming Debye length limitations:Three-dimensional wrinkled graphene field-effect transistor for ultra-sensitive adenosine triphosphate detection显示文摘Adenosine triphosphate(ATP)is closely related to the pathogenesis of certain diseases,so the detection of trace ATP is of great significance to disease diagnosis and drug development.Graphene field-effect transistors(GFETs)have been proven to be a promising platform for the rapid and accurate detection of small molecules,while the Debye shielding limits the sensitive detection in real samples.Here,a three-dimensional wrinkled graphene field-effect transistor(3D WG-FET)biosensor for ultra-sensitive detection of ATP is demonstrated.The lowest detection limit of 3D WG-FET for analyzing ATP is down to 3.01 aM,which is much lower than the reported results.In addition,the 3D WG-FET biosensor shows a good linear electrical response to ATP concentrations in a broad range of detection from 10 aM to 10 pM.Meanwhile,we achieved ultra-sensitive(LOD:10 aM)and quantitative(range from 10 aM to 100 fM)measurements of ATP in human serum.The 3D WG-FET also exhibits high specificity.This work may provide a novel approach to improve the sensitivity for the detection of ATP in complex biological matrix,showing a broad application value for early clinical diagnosis and food health monitoring. | Yue Ding Chonghui Li Meng Tian Jihua Wang Zhenxing Wang Xiaohui Lin Guofeng Liu Wanling Cui Xuefan Qi Siyu Li Weiwei Yue Shicai Xu | 2023 | Frontiers of physics2023，18，5： | 0 |
| 15 | THE HYDROSTATIC PIEZOELECTRICITY OF RELAXOR-PbTiO_(3)FERROELECTRIC CERAMICS AND CRYSTALS显示文摘The hydrostatic piezoelectricity of Pb(Mg_(1/3)Nb_(2/3))-αPbTiO_(3)(PMN-εPT)ceramics and PMN-0.32PT and Pb(Mg_(1/3)Nb_(2/3))-Pb(In_(1/2)Nb_(1/2))=PbTiO_(3)(PMN-PIN-PT)crystals wereinvestigated through a quasi-static method.The results showed that pressure-induced depolar-ization occurred in PMN-εPT ceramics when pressure was above about 50 MPa,while there wasno obvious pressure-induced depolarization for PMN-0.32PT and PMN-PIN-PT crystals inthe whole pressure range(0~530 MPa).The hydrostatic piezoelectric coeficient dh of PMN-0.32PT and PMN-PIN-PT crystals was nearly independent of pressure.The d_(h)of mono-domain orthorhombic and tetragonal phase crystals is slightly larger,on the order of 100 pC/N.In addition,the relationship between the hydrostatic piezoelectric coeficient d_(h)and the longit udinal and transverse piezoelectric coefficients d_(33)and d_(31)for different crystal systems was summarized. | JUNJIE GAO ZHUO XU FEI LI CHONGHUI ZHANG YI LIU GAOMIN LIU HONGLIANG HE | 2012 | Journal of Advanced Dielectrics2012，2，3： | 0 |
| 16 | Comparison of viral propagation and drug response among SARS-CoV-2 VOCs using replicons capable of recapitulating virion assembly and release显示文摘Several variants of concern(VOCs)have emerged since the WIV04 strain of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)was first isolated in January 2020.Due to mutations in the spike(S)protein,these VOCs have evolved to enhance viral infectivity and immune evasion.However,whether mutations of the other viral proteins lead to altered viral propagation and drug resistance remains obscure.The replicon is a noninfectious viral surrogate capable of recapitulating certain steps of the viral life cycle.Although several SARS-CoV-2 replicons have been developed,none of them were derived from emerging VOCs and could only recapitulate viral genome replication and subgenomic RNA(sgRNA)transcription.In this study,SARS-CoV-2 replicons derived from the WIV04 strain and two VOCs(the Beta and Delta variants)were prepared by removing the S gene from their genomes,while other structural genes remained untouched.These replicons not only recapitulate viral genome replication and sgRNA transcription but also support the assembly and release of viral-like particles,as manifested by electron microscopic assays.Thus,the S-deletion replicon could recapitulate virtually all the post-entry steps of the viral life cycle and provides a versatile tool for measuring viral intracellular propagation and screening novel antiviral drugs,including inhibitors of virion assembly and release.Through the quantification of replicon RNA released into the supernatant,we demonstrate that viral intracellular propagation and drug response to remdesivir have not yet substantially changed during the evolution of SARS-CoV-2 from the WIV04 strain to the Beta and Delta VOCs. | Lingqian Tian Qiuhong Liu Rongjuan Pei Yingshan Chen Chonghui Xu Jielin Tang Hao Sun Kunpeng Liu Qi Yang Lei Yang Leshan Li Yongli Zhang Yuan Zhou Chao Shan Xue Hu Xinwen Chen Yun Wang | 2022 | Virologica Sinica2022，37，5： | 0 |
| 17 | Observation of Biological Character of Drosophila melanogaster Meigen on Cherry and Screening of Its Insecticides显示文摘Indoor rearing observation and efficacy test of insecticides were conducted in 2010 to understand the biochemical characteristics of Drosophila melanogaster and high efficient insecticides against the insect pest. The results showed that D. melanogaster had preference to eight kinds of fruits with proliferation. Female adults of D. melanogaster laid eggs under epidermis of cherry fruits and newly hatched larvae caused damage on fruits. When the temperatures were (18±2) ℃ and (23±2) ℃, the egg stage was 2.4-3.0 and 1.2-1.8 d; the larval stage was 11.2-12.2 and 5.6-6.5 d; the papal stage was 9.5-10.6 and 5.0-6.2 d; one generation was 23.1-25.4 and 12.8-14.2 d, respectively. Four insecticides (including 1% emamectin benzoate EC 3 000 times dilution, 90% crystal trichlorfon 1 000 times dilution, 40% phoxim EC 1 500 times dilution and 25% buprofezin WP 2 000 times dilution) had higher control effects against D. melanogaster, with mortalities of 85.00%-100.00%, 96.67%-100.00% and 100.00% after insecticide application for 1, 3 and 6 h, respectively. | Li Deyou Chen Xiaojun Li Chonghui Geng Kun Zhang Bin Hu Jifeng Yuan Jie | 2013 | Plant Diseases and Pests2013，4，1： | 0 |
| 18 | Effect of catgut embedding at acupoints versus non-acupoints in abdominal obesity:a randomized clinical trial显示文摘OBJECTIVE:To explore the difference of catgut embedding effect between acupoints and non-acupoints in patients with abdominal obesity(AO).METHODS:In this multicenter,double-blind,randomized controlled trial,all subjects were randomly assigned into the acupoint catgut embedding(ACE)group and control group(catgut embedding at non-acupoints).With a 12-week actual intervention period and a 4-week period of follow-up.Waist circumference(WC),body weight,body mass index(BMI),hip circumference(HC)and appetite were applied and assessed at baseline and after 6,12 and 16 weeks.RESULTS:After the total intervention phase(12 weeks),the WC,body weight,BMI,HC and visual analogue scale scores of appetite,decreased significantly in the two groups as compared to the baseline(P<0.001).Meanwhile,after the 4-week follow-up,the indicators still decreased significantly in the ACE group(P<0.001).At 12 and 16 weeks,catgut embedding at acupoints showed significantly advantages to non-acupoints in WC and appetite(P<0.05).No serious adverse events were observed in ACE group and control group.CONCLUSIONS:Catgut embedding at acupoints and non-acupoints are all effective and safe for AO.ACE can effectively treat AO as expected and deliver lasting results. | ZHANG Xinghe LI Qifu YI Rong XING Chonghui JIN Yuhao MENG Jiangqiong FENG Jialei ZHAO Siwen LIANG Fanrong GUO Taipin | 2023 | Journal of Traditional Chinese Medicine2023，43，4： | 0 |
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