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| 1 | Genetic mapping of QTL for agronomic traits and grain mineral elements in rice显示文摘Malnutrition is one of the prevailing health problems worldwide, affecting a large proportion of the populations in rice-consuming countries. Breeding rice varieties with increased concentrations of elements in the grain is considered the most cost-effective approach to alleviate malnutrition. Development of molecular markers for high grain concentrations of essential elements, particularly Zn, for use in marker-assisted selection (MAS) can hasten breeding efforts to develop rice varieties with nutrient-dense grain. We performed QTL mapping for four agronomic traits: days to 50% flowering, plant height, number of tillers, grain yield, and 13 grain elements: As, B, Ca, Co, Cu, Fe, K, Mg, Mn, Mo, Na, P, and Zn, in two doubled-haploid populations derived from the crosses IR64 × IR69428 and BR29 × IR75862. These populations were phenotyped during 2015DS and 2015WS at IRRI, Los Ba os, The Philippines, and genotyped them with a 6 K SNP chip. Inclusive composite interval mapping revealed 15 QTL for agronomic traits and 50 QTL for grain element concentration. Of these, eight QTL showed phenotypic variance of >25% and 11 QTL were consistent across seasons. There were seven QTL co-localization regions containing QTL for more than two traits. Twenty five epistatic interactions were detected for two agronomic traits and seven mineral elements. Several DH lines with high Fe and Zn in polished rice were identified. These lines can be used as donors for breeding high-Zn rice varieties. Some of the major QTL can be further validated and used in MAS to improve the concentrations of nutritive elements in rice grain. | Gwen Iris Descalsota-Empleo Amery Amparado Mary Ann Inabangan-Asilo Frances Tesoro James Stangoulis Russell Reinke B.P.Mallikarjuna Swamy | 2019 | The Crop Journal2019，7，4： | 4 |
| 2 | Collaboration for success:the value of strategic collaborations for precision medicine and biomarker discovery显示文摘Precision medicine aims to provide the precise treatment for the patient with the right dose at the right point of time.Biomarkers(BM)are vital for the identification of patients who would benefit the most from individualized treatment.In addition,they help to enable the prediction of prognosis,the detection of early therapeutic and adverse effects,and may serve as surrogate endpoints in clinical trials.BM are becoming essential tools to increase productivity in drug discovery and impressively enhance the way medicine is practiced.However,the identification,sufficient validation and implementation of such BM are challenging.This process requires expertise from different areas and high resource investments.Collaborations of different partners may be helpful to overcome these challenges.In the past decade,collaborations between diagnostics and pharmaceutical companies as well as industrial–academic collaborations have been increasingly pursued.Moreover,public funding may offer support and open new opportunities to form such consortia.Herein we give an overview of the different types of collaborations,their opportunities and challenges,and describe experiences in forming strategic partnerships with other companies. | Lilla Landeck Monika Lessl Joachim Reischl Andreas Busch Patricia Carrigan Matthias Gottwald Petra Reinke Khusru Asadullah | 2016 | Advances in Precision Medicine2016，1，1： | 3 |
| 3 | Intercomparison of Himawari-8 AHI-FSA with MODIS and VIIRS active fire products显示文摘The AHI-FSA(Advanced Himawari Imager-Fire Surveillance Algorithm)is a recently developed algorithm designed to support wildfire surveillance and mapping using the geostationary Himawari-8 satellite.At present,the AHI-FSA algorithm has only been tested on a number of case study fires in Western Australia.Initial results demonstrate potential as a wildfire surveillance algorithm providing high frequency(every 10 minutes),multi-resolution fire-line detections.This paper intercompares AHI-FSA across the Northern Territory of Australia(1.4 million km2)over a ten-day period with the well-established fire products from LEO(Low Earth Orbiting)satellites:MODIS(Moderate Resolution Imaging Spectroradiometer)and VIIRS(Visible Infrared Imaging Radiometer Suite).This paper also discusses the difficulties and solutions when comparing high temporal frequency fire products with existing low temporal resolution LEO satellite products.The results indicate that the multi-resolution approach developed for AHI-FSA is successful in mapping fire activity at 500 m.When compared to the MODIS,daily AHIFSA omission error was only 7%.High temporal frequency data also results in AHI-FSA observing fires,at times,three hours before the MODIS overpass with much-enhanced detail on fire movement. | Chathura Wickramasinghe Luke Wallace Karin Reinke Simon Jones | 2020 | International Journal of Digital Earth2020，13，4： | 2 |
| 4 | 对哮喘患者自我护理的指导——合作管理显示文摘1990年,美国哮喘患者住院医护费用是1.6亿美元,另外还有急诊方面的费用约为2.95亿美元。然而,调查表明,许多相对并不昂贵的措施如卫生宣教、定期追踪以及预先计划的家庭护理,可大大减少住院及急诊患者数量。因此,当今哮喘治疗的焦点是病人教育:让病人自己治疗常见的症状。这种指导下的自我护理,被称为合作管理(co-management),它强调病人和医务人员之间的协作。 | Reinke L F 刘义兰 | 1993 | 国外医学(护理学分册)1993，12，3： | 2 |
| 5 | Compartment-specific expression and function of the chemokine IP-10/CXCL10 in a model of renal endothelial microvascular injury显示文摘 | Panzer U Steinmetz O M Reinking R R Meyer T N Fehr S Schneider A | 2006 | J Am Soc Nephrol2006，17，： | 1 |
| 6 | Erkl,2 Phosphorylates p27 (Kipl): functional evidence for a role in high glucose-induced hypertrophy of mesangial cells显示文摘 | Wolf G Reinking R Zahner G | 2003 | Diabetologia2003，46，： | 1 |
| 7 | Pedicle screw-based dynamic stabilization of the thoracolumbar spine with the Cosmic-system: a prospective observation 显示文摘 | STOFFEL M BEHR M REINKE A | 2010 | Acta Neurochi ' (Wien)2010，152，5： | 1 |
| 8 | International Prognostic Index, Type of Transplant and Response to Rituximab Are Key Parameters to Tailor Treatment in Adults With CD20‐Positive B Cell PTLD: Clues From the PTLD‐1 Trial显示文摘 | R. U. Trappe S. Choquet D. Dierickx P. Mollee J. M. Zaucha M. H. Dreyling U. Dührsen C. Tarella O. Shpilberg M. Sender G. Salles F. Morschhauser A. Jaccard T. Lamy P. Reinke R. Neuhaus H. Lehmkuhl H. A. Horst M. Leith?user P. Schlattmann I. Anagnostopoulo | 2015 | American Journal of Transplantation2015，，4： | 1 |
| 9 | Monocytc deactivationraonale for a new therapeutic strategy in sepsis显示文摘 | Volk HD Reinke P Krausch D | 1996 | Intensive Care Med1996，22，4： | 1 |
| 10 | Influence of the ion energy on the growth and structure of thin hydrocarbon films 显示文摘 | Reinke P Jacob W Moiler W | 1993 | J Appl Phys1993，74，： | 1 |
| 11 | Selenium supplementation affects broiler growth performance, meat yield and feather coverage显示文摘 | Choct M Naylor A J Reinke N | 2004 | British Poultry Science2004，45，5： | 1 |
| 12 | The Drosophila nuclear receptor E75 contains heme and is gas responsive 显示文摘 | Reinking J Lam M M S Pardee K | 2005 | Cell2005，122，2： | 1 |
| 13 | Creep and recovery显示文摘 | D Angelo J A R Dongre G Reinke | 2007 | Public roads2007，，70： | 1 |
| 14 | High-pressure catalytic combustion of methane overplatinum: In situ experiments and detailed numericalpredictions显示文摘 | Reinke M Mantzaras J Schaeren R | 2004 | Combustion and Flame2004，136，： | 1 |
| 15 | Preparation,characterization and reaction behaviour of sodium and potassium hydridosilylamides R2(H)Si-N(M)R' (MNa,K)-crystal structure of2THF显示文摘 | Schneider J Popowski E Reinke H | 2003 | Zeitschrift für anorganische und allgemeine Chemie2003，629，1： | 1 |
| 16 | Implantation and follow-up oftotally subcutaneous versus conventional implantable cardioverter-de-fibrillators: A multicenter case-control study 显示文摘 | Kobe J Reinke F Meyer C | 2012 | Heart Rhythm2012，10，1： | 1 |
| 17 | Implantation and follow-up of totally subcutaneous versus conventionalimplantable cardioverter- defibrillators:A multicenter case-control study显示文摘 | Kobe J Reinke F Meyer C | 2013 | Heart Rhythm2013，10，1： | 1 |
| 18 | Successful treatment of eatecholaminergic polymorphic ventricular tachyeardiawith {lecainide: a case report and review of the current literature 显示文摘 | Pott C Dechering DG Reinke F | 2011 | Europace2011，13，6： | 1 |
| 19 | Impairment of protein trafficking by direct interaction of gliadin peptides with actin显示文摘 | Yvonne Reinke Marc Behrendt Sonja Schmidt Klaus-Peter Zimmer Hassan Y. Naim | 2011 | Experimental Cell Research2011，，15： | 1 |
| 20 | Explosive vaporization of super- heated liquids by boiling fronts 显示文摘 | Reinke P Yadigarroglu G | 2001 | International Journal of Muhiphase Flow2001，27，9： | 1 |
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