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| 1 | 波士顿人工角膜临床应用及其进展显示文摘波士顿人工角膜是全世界应用范围最广,最成功的人工角膜之一,它适用于严重角膜疾病和多次角膜移植失败的病例.它的长期预后因病种不同而不同,自身免疫性疾病,如瘢痕性类天疱疮和Stevens-Johnson综合征、中毒性表皮坏死溶解症,以及严重化学烧伤等疾病的预后较非感染性角膜病的预后差.在适应证的扩展方面,儿童遗传性角膜混浊病早期植入人工角膜可以有效地减少弱视的发生.波士顿人工角膜采用“领扣”式设计,使用聚甲基丙烯酸甲酯的生物材料.波士顿人工角膜使用供体角膜,也可使用患者自体角膜作为载体.针对我国角膜供体材料匮乏的特点,采用自体角膜为载体为角膜盲患者复明提供了一种选择.波士顿人工角膜经过多次改进,减少了严重并发症的发生,其中包括后盘的多孔设计,使角膜植片能够从房水中获得充足的营养,减少了角膜溶解的发生率,持续性佩戴角膜接触镜有效地防止了眼表水分的蒸发,有效地减少角膜组织的坏死和溶解,人工角膜的在位率明显提高.术后预防性地使用抗生素有效地预防了感染的发生,从而降低了眼内炎的发生率. | 王丽强 黄一飞 James Chodosh Claes H.Dohlman | 2014 | 中华眼科杂志2014，50，4： | 4 |
| 2 | Tracking SARS-CoV-2 Omicron diverse spike gene mutations identifies multiple inter-variant recombination events显示文摘The current pandemic of COVID-19 is fueled by more infectious emergent Omicron variants.Ongoing concerns of emergent variants include possible recombinants,as genome recombination is an important evolutionary mechanism for the emergence and re-emergence of human viral pathogens.In this study,we identified diverse recombination events between two Omicron major subvariants(BA.1 and BA.2)and other variants of concern(VOCs)and variants of interest(VOIs),suggesting that co-infection and subsequent genome recombination play important roles in the ongoing evolution of SARS-CoV-2.Through scanning high-quality completed Omicron spike gene sequences. | Junxian Ou Wendong Lan Xiaowei Wu Tie Zhao Biyan Duan Peipei Yang Yi Ren Lulu Quan Wei Zhao Donald Seto James Chodosh Zhen Luo Jianguo Wu Qiwei Zhang | 2022 | Signal Transduction and Targeted Therapy2022，7，5： | 3 |
| 3 | Silent stroke in the NINCDS stroke data bank显示文摘 | CHODOSH E H FOULKES M A KASE C S | 1988 | Neurology1988，38，： | 1 |
| 4 | mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging显示文摘 | Castilho RM Squarize CH Chodosh LA | 2009 | Cell Stem Cell2009，5，3： | 1 |
| 5 | Pharmacokinetics and pharmacodynamics of oral grepatloxacin in patients with acute bacterial exacerbations of chronic bronchitis 显示文摘 | Forrest A Chodosh S Amantea MA | 1997 | J Antimicrob Chemother1997，40，： | 1 |
| 6 | Short-course moxifloxacin therapy for treatment of acute bacterical exacerbations of chronic bronchitis显示文摘 | Chodosh S DeAbate CA Haverstock D | 2000 | Respir Med2000，94，1： | 1 |
| 7 | Partial dislocation of laser in situ keratomileusis flap by air bag injury 显示文摘 | Lemley HL Chodosh J Wclf TC | 2000 | J Refract Surg2000，16，3： | 1 |
| 8 | Diagnostic and therapeutic considerations in fungal keratitis显示文摘 | Chang HY Chodosh J | 2011 | Int Ophthalmol Clin2011，51，4： | 1 |
| 9 | Depres- sive symptoms, chronic diseases, and physical disabilities as predictors of cognitive functioning trajectories in older Ameri- cans 显示文摘 | Chodosh J Miller-Martinez D Aneshensel CS | 2010 | J Am Geriatr Soc2010，58，12： | 1 |
| 10 | mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging显示文摘 | Castilho RM Squarize CH Chodosh LA | 2009 | Cell Stem Cell2009，5，3： | 1 |
| 11 | Partial dislocation of laser in situ keratomileusis flap by air bag injury显示文摘 | Lemley HL Chodosh J Wolf TC | 2000 | J Refract Surg2000，16，3： | 1 |
| 12 | 显示文摘 | Chodosh J Can Y Holder VP | 2000 | Virology2000，266，2： | 1 |
| 13 | Breast cancer: current state and future promise显示文摘 | Chodosh LA | 2011 | Breast Cancer Research2011，13，6： | 1 |
| 14 | Differential roles of hypoxia-inducible factor 1alpha(HIF-1alpha)and HIF-2alpha in hypoxic gene regulation显示文摘 | Hu CJ Wang LY Chodosh LA | | 0，，： | 1 |
| 15 | Evidence-based treatment of herpes simplex virus keratitis: a systematic review显示文摘 | Guess S Stone DU Chodosh J | 2007 | Ocul Surf2007，5，3： | 1 |
| 16 | Using the whole-genome sequence to characterize and name human adenoviruse显示文摘 | Seto D Chodosh J Brister JR | 2011 | J Virol2011，85，： | 1 |
| 17 | Silent stroke in the NINCDS stroked at a bank显示文摘 | Chodosh EH Foulkes MA Kase CS | 1988 | Neurology1988，38，： | 1 |
| 18 | Meta-Analysis: Chronic disease serf-management programs for older adults 显示文摘 | J Chodosh SC Morton W Mojica M Maglione | 2005 | Annals of Internal medicine2005，143，： | 1 |
| 19 | Prevalence of silent stroke in patients presenting with initial stroke :The Framingham study显示文摘 | Kase C S Wolf P A Chodosh E H | 1989 | Stroke1989，20，7： | 1 |
| 20 | Using the whole-genome se- quence to characterize and name human adenoviruses 显示文摘 | Seto D Chodosh J Brister JR | 2011 | J Virol2011，85，11： | 1 |
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