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| 1 | Brain MRI of hippocampal volumetry in patients with refractory temporal lobe epilepsy显示文摘Objective To detect for hippocampal sclerosis presurgically in a group of patients with refractory temporal lobe epilepsy Methods Eighty four consecutive patients with refractory temporal lobe epilepsy were subjected to brain MRI of hippocampal volumetry A ratio of smaller to larger hippocampal volume was determined and unilateral hippocampal atrophy (HA) was diagnosed if the ratio is less than 0 91 Results Unilateral HA was diagnosed in 42 patients (50%) and bilateral HA in 1 patient Other MRI abnormalities were detected in 18 patients with or without coexisting HA Conclusions Hippocampal sclerosis can be detected presurgically in many patients by brain MRI Additional abnormalities not detected by brain CT can also be | Ka Kui Philip Ng, Kwok Wing Tang, Yuk Ling James Cheung and Patrick Chung Ki Li | 2000 | Chinese Medical Journal2000，，3： | 3 |
| 2 | Antifungal and antiviral products of marine organisms显示文摘 | Randy Chi Fai Cheung Jack Ho Wong Wen Liang Pan Yau Sang Chan Cui Ming Yin Xiu Li Dan He Xiang Wang Evandro Fei Fang Sze Kwan Lam Patrick Hung Kui Ngai Li Xin Xia Fang Liu Xiu Yun Ye Guo Qing Zhang Qing Hong Liu Ou Sha Peng Lin Chan Ki Adnan A Bekhit Alaa | 2014 | Applied Microbiology and Biotechnology2014，，8： | 2 |
| 3 | Endoscopic stenting for malignant biliary obstruction显示文摘 | Cheung KI Laiec | 1995 | Arcg Surg1995，，2： | 1 |
| 4 | The Effect of Peer Instruction on Promoting Student Nurses' Learning in Medical-Surgical Nursing显示文摘 | Mei Ki Cheung Julia Sze Wing Wong | 2016 | US-China Education Review(A)2016，6，12： | 1 |
| 5 | Systematic review of clinical trials comparing open and endovascular treatment of abdominal aortic aneurysm显示文摘 | Pei Ho Wai Ki Yiu Grace Chung-Yan Cheung | 2006 | Surgical Practice2006，10，1： | 1 |
| 6 | The plasma lipidomic signature of nonalcoholic steatohepatitis显示文摘 | Puneet Puri Michelle M. Wiest Onpan Cheung Faridoddin Mirshahi Carol Sargeant Hae‐Ki Min Melissa J. Contos Richard K. Sterling Michael Fuchs Huiping Zhou Steven M. Watkins Arun J. Sanyal | 2009 | Hepatology2009，，6： | 1 |
| 7 | Assessment of Fibrosis by Transient Elastography Compared With Liver Biopsy and Morphometry in Chronic Liver Diseases显示文摘 | Grace Lai–Hung Wong Vincent Wai–Sun Wong Paul Cheung–Lung Choi Anthony Wing–Hung Chan Richard Hoi–Leong Chum Henry Kai–Wing Chan Kenneth Ka–Ki Lau Angel Mei–Ling Chim Karen Ka–Lam Yiu Francis Ka–Leung Chan Joseph Jao–Yao Sung Henry Lik–Yuen Chan | 2008 | Clinical Gastroenterology and Hepatology2008，，9： | 1 |
| 8 | The inventory benefit of shipment coordination and stock rebalancing in a supply chain 显示文摘 | Ki Ling Cheung Hau 1 lee | 2001 | Management Science2001，48，2： | 1 |
| 9 | Potassium permanganate poisoning a rare cause of fatal sell' poisoning显示文摘 | Ong KI Tan TH Cheung WI | 1997 | Accid Emerg Med1997，14，： | 1 |
| 10 | X-reality for phantom limb management for amputees:A systematic review and meta-analysis显示文摘Phantom limb is a disabling neuropsychiatric condition among amputees resulting in pain and disturbance that impact their functions,quality of life,and autonomy.While pharmacological approaches appeared to be ineffec-tive,the emergence and integration of X-reality,including virtual reality,augmented reality,and mixed reality,might elevate the effectiveness of mirror therapy in managing phantom limb.The objective of this study is to review X-reality for managing phantom pain.A systematic search was conducted on PubMed,Scopus,Web of Science,PsycINFO,Embase,and CINAHL.Sixteen(n=16)studies containing 66 lower-limb and 53 upper-limb amputees were included for the review over the thematic framework of amputee characteristics and intervention designs,while thirteen(n=13)studies were further proceeded for the meta-analysis.We found eleven studies on virtual reality(n=11),four studies on marker-based augmented reality(n=4)and one study on mixed reality(n=1)with a total of 40 game/task themes involving,motor skills,motor control,and stimulus-sensing.Regardless,all these interventions adopted the movement representation strategies with different techniques.Overall,the X-reality interventions reduced the pain level of the amputees(mean difference:-2.30,95%CI,-3.38 to-1.22),especially the virtual reality subgroup(mean difference:-2.83,95%CI,-4.43 to-1.22).However,there were substantial heterogeneity and partially explained by the subgroup analysis on publication year.The strength of evidence was limited by case reports and case series in this review. | James Chung-Wai Cheung Daphne Sze Ki Cheung Ming Ni Kam-Wai Chen Ye-Jiao Mao Lin Feng Wing-Kai Lam Duo Wai-Chi Wong Aaron Kam-Lun Leung | 2023 | Engineered Regeneration2023，4，2： | 0 |
| 11 | Corrigendum to‘Dual ultra-wideband(UWB)radar-based sleep posture recognition system:Towards ubiquitous sleep monitoring’[Engineered Regeneration 4(2023)36-43]显示文摘The authors regret that the name of the ethic committee that approved the study and the reference number was omitted from the published paper.In this research,all participants signed an informed consent after receiving an oral and written description of the experiment before the start of the experiment.The study was approved by the Human Subjects Ethics HSEARS20210127007. | Derek Ka-Hei Lai Li-Wen Zha Tommy Yau-Nam Leung Andy Yiu-Chau Tam Bryan Pak-Hei So Hyo Jung Lim Daphne Sze Ki Cheung Duo Wai-Chi Wong James Chung-Wai Cheung | 2023 | Engineered Regeneration2023，4，2： | 0 |
| 12 | Genomics-driven derivatization of the bioactive fungal sesterterpenoid variecolin:Creation of an unnatural analogue with improved anticancer properties显示文摘A biosynthetic gene cluster for the bioactive fungal sesterterpenoids variecolin(1)and variecolactone(2)was identified in Aspergillus aculeatus ATCC 16872.Heterologous production of 1 and 2 was achieved in Aspergillus oryzae by expressing the sesterterpene synthase VrcA and the cytochrome P450 VrcB.Intriguingly,the replacement of VrcB with homologous P450s from other fungal terpenoid pathways yielded three new variecolin analogues(5-7).Analysis of the compounds’anticancer activity in vitro and in vivo revealed that although 5 and 1 had comparable activities,5 was associated with significantly reduced toxic side effects in cancer-bearing mice,indicating its potentially broader therapeutic window.Our study describes the first tests of variecolin and its analogues in animals and demonstrates the utility of synthetic biology for creating molecules with improved biological activities. | Dexiu Yan Jemma Arakelyan Teng Wan Ritvik Raina Tsz Ki Chan Dohyun Ahn Vladimir Kushnarev Tsz Kiu Cheung Ho Ching Chan Inseo Choi Pui Yi Ho Feijun Hu Yujeong Kim Hill Lam Lau Ying Lo Law Chi Seng Leung Chun Yin Tong Kai Kap Wong Wing Lam Yim Nikolay S.Karnaukhov Richard Y.C.Kong Maria V.Babak Yudai Matsuda | 2024 | Acta Pharmaceutica Sinica B2024，14，1： | 0 |
| 13 | Dual ultra-wideband(UWB)radar-based sleep posture recognition system:Towards ubiquitous sleep monitoring显示文摘Sleep posture monitoring is an essential assessment for obstructive sleep apnea(OSA)patients.The objective of this study is to develop a machine learning-based sleep posture recognition system using a dual ultra-wideband radar system.We collected radiofrequency data from two radars positioned over and at the side of the bed for 16 patients performing four sleep postures(supine,left and right lateral,and prone).We proposed and evaluated deep learning approaches that streamlined feature extraction and classification,and the traditional machine learning approaches that involved different combinations of feature extractors and classifiers.Our results showed that the dual radar system performed better than either single radar.Predetermined statistical features with random forest classifier yielded the best accuracy(0.887),which could be further improved via an ablation study(0.938).Deep learning approach using transformer yielded accuracy of 0.713. | Derek Ka-Hei Lai Li-Wen Zha Tommy Yau-Nam Leung Andy Yiu-Chau Tam Bryan Pak-Hei So Hyo-Jung Lim Daphne Sze Ki Cheung Duo Wai-Chi Wong James Chung-Wai Cheung | 2023 | Engineered Regeneration2023，4，1： | 0 |
| 14 | Acquisition repeatability of MRI radiomics features in the head and neck:a dual-3D-sequence multi-scan study显示文摘Radiomics has increasingly been investigated as a potential biomarker in quantitative imaging to facilitate personalized diagnosis and treatment of head and neck cancer(HNC),a group of malignancies associated with high heterogeneity.However,the feature reliability of radiomics is a major obstacle to its broad validity and generality in application to the highly heterogeneous head and neck(HN)tissues.In particular,feature repeatability of radiomics in magnetic resonance imaging(MRI)acquisition,which is considered a crucial confounding factor of radiomics feature reliability,is still sparsely investigated.This study prospectively investigated the acquisition repeatability of 93 MRI radiomics features in ten HN tissues of 15 healthy volunteers,aiming for potential magnetic resonance-guided radiotherapy(MRgRT)treatment of HNC.Each subject underwent four MRI acquisitions with MRgRT treatment position and immobilization using two pulse sequences of 3D T1-weighed turbo spin-echo and 3D T2-weighed turbo spin-echo on a 1.5T MRI simulator.The repeatability of radiomics feature acquisition was evaluated in terms of the intraclass correlation coefficient(ICC),whereas within-subject acquisition variability was evaluated in terms of the coefficient of variation(CV).The results showed that MRI radiomics features exhibited heterogeneous acquisition variability and uncertainty dependent on feature types,tissues,and pulse sequences.Only a small fraction of features showed excellent acquisition repeatability(ICC>0.9)and low within-subject variability.Multiple MRI scans improved the accuracy and confidence of the identification of reliable features concerning MRI acquisition compared to simple test-retest repeated scans.This study contributes to the literature on the reliability of radiomics features with respect to MRI acquisition and the selection of reliable radiomics features for use in modeling in future HNC MRgRT applications. | Cindy Xue Jing Yuan Yihang Zhou Oi Lei Wong Kin Yin Cheung Siu Ki Yu | 2022 | Visual Computing for Industry,Biomedicine,and Art2022，5，1： | 0 |
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