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| 1 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 2 | Diagnosis in bile acid-CoA:Amino acid N-acyltransferase deficiency显示文摘Cholate-CoA ligase(CCL) and bile acid-CoA:amino acid N-acyltransferase(BAAT) sequentially mediate bile-acid amidation.Defects can cause intrahepatic cholestasis.Distinction has required gene sequencing.We assessed potential clinical utility of immunostaining of liver for CCL and BAAT.Using commercially available antibodies against BAAT and CCL,we immunostained liver from an infant with jaundice,deficiency of amidated bile acids,and transcription-terminating mutation in BAAT.CCL was normally expressed.BAAT expression was not detected.Immunostaining may facilitate diagnosis in bileacid amidation defects. | Nedim Hadzi Laura N Bull Peter T Clayton AS Knisely | 2012 | World Journal of Gastroenterology2012，18，25： | 3 |
| 3 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 4 | E-Cadherin gene promoter hypermethylation in primary human gastric carcinomas显示文摘 | Tamura G Yin J Wang S Fleisher AS Zou T Abraham JM Kong D Smolinski KN Wilson KT James SP Silverberg SG Nishizuka S Terashima M Motoyama T Meltzer SJ | | 0，，： | 2 |
| 5 | Effects of temperature and body weight on growth rate and feed conversion ratio in turbot ( Scophthalmus maximus )显示文摘 | Tómas árnason Bj?rn Bj?rnsson Agnar Steinarsson Matthías Oddgeirsson | 2009 | Aquaculture2009，，3： | 2 |
| 6 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 7 | A simplified equation to predict glomerular filtration rate from serum creatinine 显示文摘 | Levery AS Greene T Kusek JW | 2000 | J Am Soc Nephrol2000，11，： | 1 |
| 8 | Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers显示文摘 | Read MA Neish AS | 1995 | FASEB J1995，9，： | 1 |
| 9 | Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis显示文摘 | Karban AS Okazaki T Panhuysen CI | 2004 | Hum Mol Genet2004，13，1： | 1 |
| 10 | Myocardial cell death in fibrillation and dilated human right artia显示文摘 | Christine AS Folliguet T Catherine RM | 1999 | J Am Coll Cardiol1999，34，5： | 1 |
| 11 | Preparation of Magnetically Labeled Cells for Cell Tracking by Magnetic Resonance Imaging显示文摘 | BULTE JW ARBAB AS DOUGLAS T | 2004 | Methods Enzymol (S0076-6879)2004，386，： | 1 |
| 12 | A simplified equation to pre- dict glomerular fihration Rate from serum creatinine 显示文摘 | Levey AS Greene T Kusek J | 2000 | J Am Soc Nephrol2000，，： | 1 |
| 13 | Severe hyperchol- esterolemia and atheroselerosis in apolipoprotein E-defi- cient mice created by homologous recombination in ES cells显示文摘 | Plump AS Smith JD Hayek T | 1992 | Cell1992，71，2： | 1 |
| 14 | Effects of bone density al- terations on strain patterns in the pelvis: application of a finite ele- ment model显示文摘 | Leung AS Gordon LM Skrinskas T | 2009 | Proc Inst Mech Eng H2009，223，8： | 1 |
| 15 | Somatic mutations of calreticulin in myeloproliferative neoplasms显示文摘 | Klampfl T Gisslinger H Harutyunyan AS | 2013 | EnglJ Med2013，369，25： | 1 |
| 16 | Adjuvant effective as fluorouracil plusleucovorin for survival in people with resected stage III colon cancer 显示文摘 | Lamberti C Sauerbruch capecitabine is at least as T Glasmacher A | 2005 | Cancer Treat Rev2005，31，8： | 1 |
| 17 | Genome classification of banana cuhivars from South India using IRAP markers 显示文摘 | Nair AS Teo CH Schwarzacher T Harrison PH | 2005 | Euphytica2005，144，： | 1 |
| 18 | Immune function in young children with previous pulmonary or miliary/meningeal tuberculosis and impact of BCG vaccination 显示文摘 | Terling TR Martire T de Almeida AS | 2007 | Pediatrics2007，120，4： | 1 |
| 19 | Severe hypercholesqerolemia and atheroslerosis in apolipoprotein E-deficient mice created by ho-mologous recombination in ES cells显示文摘 | Plump AS Smith JD Hayek T | 1992 | Cell1992，71，10： | 1 |
| 20 | Multiple pathways of repair of DNA double-strand breaks in mammalian chromosomes显示文摘 | Lin Y Lukacsovich T Waldman AS | 1999 | Mol Cell Biol1999，19，： | 1 |
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