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| 1 | Lymph node ratio and preoperative CA 19-9 levels predict overall survival and recurrence-free survival in patients with resected pancreatic adenocarcinoma显示文摘AIM:Clinicopathologic factors predicting overall survival (OS) would help identify a subset to benefit from adjuvant therapy. METHODS: One hundred and sixty-nine patients patients from 1984 to 2009 with curative resections for pancreatic adenocarcinoma were included. Tumors were staged by American Joint Committee on Cancer 7th edition criteria. Univariate and multivariable analyses were performed using Kaplan-Meier methodology or Cox proportional hazard models. Log-rank tests were performed. Statistical inferences were assessed by two-sided 5% significance level. RESULTS: Median age was 67.1 (57.2-73.0) years with equal gender distribution. Tumors were in the head (89.3%) or body/tail (10.7%). On univariate analysis, adjuvant therapy, lymph node (LN) ratio, histologic grade, negative margin status, absence of peripancreatic extension, and T stage were associated with improved OS. Adjuvant therapy, LN ratio, histologic grade, number of nodes examined, negative LN status, and absence of peripancreatic extension were associated with improved recurrence-free survival (RFS). On multivariable analysis, LN ratio and carbohydrate antigen (CA) 19-9 levels were associated with OS. LN ratio was associated with RFS. CONCLUSION: The LN ratio and CA 19-9 levels are independent prognostic factors following curative resections of pancreatic cancer. | Sabrina C Wentz Zhi-Guo Zhao Yu Shyr Chan-Juan Shi Kay Washington Nipun B Merchant Fen Xia A Bapsi Chakravarthy | 2012 | World Journal of Gastrointestinal Oncology2012，4，10： | 3 |
| 2 | Alternative treatments to inhibit VEGF in age-related choroidal neovascularisation: 2-year findings of the IVAN randomised controlled trial显示文摘 | Usha Chakravarthy Simon P Harding Chris A Rogers Susan M Downes Andrew J Lotery Lucy A Culliford Barnaby C Reeves | 2013 | The Lancet2013，，： | 2 |
| 3 | Tile amniotic mem- brane in oral and maxillofacial surgery-an overview 显示文摘 | Sujan S Rathore K Chakravarthy C | 2014 | Annals and Essences of Dentistry2014，6，1： | 1 |
| 4 | Tomato tran- scription factors pti4, pti5, and pti6 activate defense responses when expressed in Arabidopsis defense against Botrytis cinerea in Arabidopsis显示文摘 | Gu Y Q Wildermuth M C Chakravarthy S | 2002 | Plant Cell2002，14，： | 1 |
| 5 | Evidence from cultured rat cortical neurons of differences in the mechanism of ischemic preconditioning of brain and heart显示文摘 | TAUSKELA J S CHAKRAVARTHY B R MURRAY C L | 1999 | Brain Res1999，827，12： | 1 |
| 6 | Neoadjuvant concurrent paclitaxel and radiation in stage Ⅱ/Ⅲ breast cancer显示文摘 | Chakravarthy A B Kelley M C McLaren B | 2006 | Clin Cancer Res2006，12，5： | 1 |
| 7 | Mutational screening of the RB1 gene in Indian patients with retinoblastoma reveals eight novel and several recurrent mutations显示文摘 | Kiran VS Kannabiran C Chakravarthi K | 2003 | Hum Mutat2003，22，： | 1 |
| 8 | Autogenous regulation of a networkof BMPs mediates the osteogenic differentiationin murine marrow stromal cells显示文摘 | Edgar C M Chakravarthy V Barnes G | | 0，，03： | 1 |
| 9 | The tomato transcription factor Pti4 regulates defense-related gene expression via GCC box and non-GCC box cis elements显示文摘 | Chakravarthy S Tuori R P D'Ascanzo M D Fobert P R Despres C Martin G B | | 0，，： | 1 |
| 10 | Minimizing destruction of thermodynamic availability in hydrogen combustion 显示文摘 | Daw C S Chakravarthy K Con/din J C | 2006 | International Journal of Hydrogen Energy2006，31，6： | 1 |
| 11 | Tomato transcription factors Pti4, Pti5, and Pti6 activate defense responses when expressed in Arabidopsis显示文摘 | Gu Y Q Wildermuth M C Chakravarthy S | 2002 | Plant Cell2002，14，4： | 1 |
| 12 | Relation between macular morphology and visual function in patients with choroidal neovascularisation of age related macular degeneration显示文摘 | Doris N Hart PM Chakravarthy U McCleland J Stevenson M Hudson C | 2001 | Br J Ophthalmol2001，85，： | 1 |
| 13 | Tomato transcription factors Pti4, Pti5 and Pti6 activate defense responses when expressed in Arabidopsis显示文摘 | Gu Y Q Wildermuth M C Chakravarthy S | 2002 | Plant Cell2002，14，4： | 1 |
| 14 | The Tomato Transcription Factor Pti4Regulates Defense-Related Gene Expression via GCC Box and Non-GCC Box cis Elements显示文摘 | Chakravarthy S Tuori RP D'Ascenzo MD Fobert PR Despres C Martin GB | 2003 | Plant Cell2003，15，： | 1 |
| 15 | Cigarette smoking and age-related macular degeneration in the EUREYE Study显示文摘 | Chakravarthy U Augood C Bentham GC | 2007 | Ophthalmology2007，114，： | 1 |
| 16 | Methods to study PAMP-triggered immunity using tomato and Nicotiana benthamiana显示文摘 | Nguyen H P Chakravarthy S Velisquez A C | 2010 | Molecular Plant- Microbe Interactions2010，23，8： | 1 |
| 17 | Pathogenicity and management of phomopsis blight and leaf spot in brinjal caused by Phomopsis vexans and alternaria solani显示文摘 | Thippeswamy B Krishnappa M Chakravarthy C N | 2006 | Indian Phytopathology2006，59，4： | 1 |
| 18 | Tomato transcription factors Pti4,Pti5,and Pti6 activate defense responses when expressed in Arabidopsis显示文摘 | GU Yongqiang WILDERMUTH M C CHAKRAVARTHY S | | 0，，04： | 1 |
| 19 | Toma- to transcription factors Pti4, Pti5, and Pti6 activate defense re- sponses when expressed in Arabidopsis显示文摘 | GU Yong-qiang Wildermuth M C Chakravarthy S | 2002 | The Plant Cell2002，14，： | 1 |
| 20 | Tomato transcription factors pti4, pti5, and pti6 activate defense responses when expressed in Arabidopsis 显示文摘 | Gu Y Q Wildermuth M C Chakravarthy S | 2002 | Plant Cell2002，14，： | 1 |
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