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| 1 | 尼可地尔在经皮冠状动脉介入治疗不稳定心绞痛时对心肌的保护作用显示文摘心肌损伤通常在经皮冠状动脉介入治疗(PCI)过程中出现,并且损伤可以通过对心肌酶的测试使之容易被监控。众所周知,尼可地尔是三磷酸腺苷ATP-敏感的K+通道的开启器,通过减小作用电位从而具有抗心律失常效应和保护心脏作用。比如,通过松弛血管平滑肌以减少微冠状动脉血流阻力。研究尼可地尔的心肌保护作用,IONA研究(尼可地尔对心绞痛的作用)即大规模对稳定型心绞痛进行的研究表明,尼可地尔口服给药能够减少冠心病致死率和非致命型心肌梗塞或胸痛意外住院治疗。目前已经对数个不稳定心绞痛(UAP)或急性心肌梗塞病人进行了尼可地尔心脏保护效应的研究评估,但还没有进行大规模研究。此研究的目的在于通过对经尼可地尔注射并PCI治疗12~48h后的不稳定心绞痛患者的心肌酶进行评估来预期考察尼可地尔的心脏保护作用。 | Ju Han Kim Myung Ho Jeong Kyung Ho Yun Kye Hun Kim Dong Koo Kang Seo Na Hong Sang Yup Lim Sang Hyun Lee Yun Sang Lee Young Joon Hong Hyung Wook Park Weon Kim Young Keun Ahn Jeong Gwang Cho Jong Chun Park Jung Chaee Kang 田玉敬 | 2017 | 首都食品与医药2017，24，18： | 3 |
| 2 | Predictive value of glycosylated hemoglobin for mortality of patients with acute myocardial infarction undergoing percutaneous coronary intervention显示文摘 | Min Goo Lee Myung Ho Jeong Dong Han Kim Ki Hong Lee Keun Ho Park Doo Sun Sim Hyun Ju Yoon Nam Sik Yoon Kye Hun Kim Hyoung Wook Park Young Joon Hong Ju Han Kim Youngkeun Ahn Jeong Gwan Cho Jong Chun Park Jung Chaee Kang | 2012 | International Journal of Cardiology2012，，1： | 1 |
| 3 | Clinical impact of thrombus aspiration during primary percutaneous coronary intervention: Results from Korea Acute Myocardial Infarction Registry显示文摘 | Daisuke Hachinohe Myung Ho Jeong Shigeru Saito Min Chol Kim Kyung Hoon Cho Khurshid Ahmed Seung Hwan Hwang Min Goo Lee Doo Sun Sim Keun-Ho Park Ju Han Kim Young Joon Hong Youngkeun Ahn Jung Chaee Kang Jong Hyun Kim Shung Chull Chae Young Jo Kim Seung Ho H | 2012 | Journal of Cardiology2012，，3： | 1 |
| 4 | 尼可地尔在经皮冠状动脉介入治疗不稳定心绞痛时对心肌的保护作用显示文摘2结果
在200例患者中,36例由于其胸痛不是缺血性心脏病引起的而被排除,9例由于胸痛难以控制在给药12h内需要进行紧急冠状动脉造影术,另外155例在给药12-48h间进行选择性冠状动脉造影术。在155例中,39例没有明显表现出冠状动脉狭窄,13例由于PCI没有表明因此进行了冠状动脉旁路移植术或内科治疗,结果,103例患者接受了PCI,由于没有血液回流或旁支路闭塞,6例按计划或因需要抢救服用IIb/IIIa抑制剂,1例由于完全性心脏传导阻滞需抢救而使用临时起搏器. | Ju Han Kim Myung Ho Jeong Kyung Ho Yun Kye Hun Kim Dong Koo Kang Seo Na Hong Sang Yup Lim Sang Hyun Lee Yun Sang Lee Young Joon Hong Hyung Wook Park Weon Kim Young Keun Ahn Jeong Gwang Cho Jong Chun Park Jung Chaee Kang 田玉敬(译) | 2017 | 首都食品与医药2017，24，24： | 1 |
| 5 | Impact of Baseline Plaque Components on Plaque Progression in Nonintervened Coronary Segments in Patients With Angina Pectoris on Rosuvastatin 10 mg/day显示文摘 | Young Joon Hong Myung Ho Jeong Yun Ha Choi Eun Hye Ma Jum Suk Ko Min Goo Lee Keun Ho Park Doo Sun Sim Nam Sik Yoon Hyun Ju Youn Kye Hun Kim Hyung Wook Park Ju Han Kim Youngkeun Ahn Jeong Gwan Cho Jong Chun Park Jung Chaee Kang | 2010 | The American Journal of Cardiology2010，，9： | 1 |
| 6 | Endothelial dysfunction, increased carotid artery intima-media thickness and pulse wave velocity, and increased level of inflammatory markers are associated with variant angina显示文摘 | Sook Hee Cho Myung Ho Jeong In Hyae Park Jin Soo Choi Hyun Ju Yoon Kye Hun Kim Young Joon Hong Hyung Wook Park Ju Han Kim Youngkeun Ahn Jeong Gwan Cho Jong Chun Park Jung Chaee Kang | 2009 | Journal of Cardiology2009，，2： | 1 |
| 7 | Plaque Characteristics in Culprit Lesions and Inflammatory Status in Diabetic Acute Coronary Syndrome Patients显示文摘 | Young Joon Hong Myung Ho Jeong Yun Ha Choi Jum Suk Ko Min Goo Lee Won Yu Kang Shin Eun Lee Soo Hyun Kim Keun Ho Park Doo Sun Sim Nam Sik Yoon Hyun Ju Yoon Kye Hun Kim Hyung Wook Park Ju Han Kim Youngkeun Ahn Jeong Gwan Cho Jong Chun Park Jung Chaee Kang | 2009 | JACC: Cardiovascular Imaging2009，，3： | 1 |
| 8 | MTE water re- mediation using Loy Yang brown coal as a ? lter bed adsorbent 显示文摘 | Butler C J Green A M Chaee A L | 2008 | Fuel2008，，87： | 1 |
| 9 | Quantification of malonylcarnitine in dried blood spots by use of MS/MS varies by stable isotope internal standard composition 显示文摘 | Chaee DH Lira T Hansen CR | 2009 | Cliniea Chimica Acta2009，402，12： | 1 |
| 10 | Relation of Soft Plaque and Elevated Preprocedural High-Sensitivity C-Reactive Protein Levels to Incidence of In-Stent Restenosis After Successful Coronary Artery Stenting显示文摘 | Young Joon Hong Myung Ho Jeong Sang Yup Lim Sang Rok Lee Seo Na Hong Kye Hun Kim Il Suk Sohn Hyung Wook Park Ju Han Kim Weon Kim Youngkeun Ahn Jeong Gwan Cho Jong Chun Park Jung Chaee Kang | 2006 | The American Journal of Cardiology2006，，3： | 1 |
| 11 | Predictors of no-reflow after percutaneous coronary intervention for culprit lesion with plaque rupture in infarct-related artery in patients with acute myocardial infarction显示文摘 | Young Joon Hong Myung Ho Jeong Yun Ha Choi Jum Suk Ko Min Goo Lee Won Yu Kang Shin Eun Lee Soo Hyun Kim Keun Ho Park Doo Sun Sim Nam Sik Yoon Hyun Ju Youn Kye Hun Kim Hyung Wook Park Ju Han Kim Youngkeun Ahn Jeong Gwan Cho Jong Chun Park Jung Chaee Kang | 2009 | Journal of Cardiology2009，，1： | 1 |
| 12 | Comparison of peri-procedural platelet inhibition with prasugrel versus adjunctive cilostazol to dual anti-platelet therapy in patients with ST segment elevation myocardial infarction显示文摘 | Keun-Ho Park Myung Ho Jeong Ki Hong Lee Doo Sun Sim Hyun Ju Yoon Nam Sik Yoon Kye Hun Kim Hyung Wook Park Young Joon Hong Ju Han Kim Youngkeun Ahn Jeong Gwan Cho Jong Chun Park Jung Chaee Kang | 2014 | Journal of Cardiology2014，，2： | 1 |
| 13 | 尼可地尔在经皮冠状动脉介入治疗不稳定心绞痛时对心肌的保护作用显示文摘(接2017年12月下)
3讨论
PCI治疗中的冠状动脉疾病患者均出现了心肌肌钙蛋白浓度升高的现象,这是由于PCI过程中心肌细胞被破坏所致。然而,心肌肌钙蛋白浓度并没有很好地被用于监测成功PCI之后对心肌细胞的破坏作用。心肌肌钙蛋白是控制心肌收缩的一种蛋白,且在正常的血液中不会被检测到,因为它是心脏特性指标, | Ju Han Kim Myung Ho Jeong Kyung Ho Yun Kye Hun Kim Dong Koo Kang Seo Na Hong Sang Yup Lim Sang Hyun Lee Yun Sang Lee Young Joon Hong Hyung Wook Park Weon Kim Young Keun Ahn Jeong Gwang Cho Jong Chun Park Jung Chaee Kang 田玉敬 | 2018 | 首都食品与医药2018，25，1： | 0 |
| 14 | 尼可地尔在经皮冠状动脉介入治疗不稳定心绞痛时对心肌的保护作用显示文摘1.2冠状动脉造影术和PCI冠状动脉造影术主要利用5或6号法国冠状动脉插管器(Judkins或Amplatz)作用于桡动脉或者股动脉。损伤按照美国大学心脏学/美国心脏学会(ACC/AHA)标准进行分类,冠状动脉血流量用心肌梗塞中血栓的溶解来评估。 | Ju Han Kim Myung Ho Jeong Kyung Ho Yun Kye Hun Kim Dong Koo Kang Seo Na Hong Sang Yup Lim Sang Hyun Lee Yun Sang Lee Young Joon Hong Hyung Wook Park Weon Kim Young Keun Ahn Jeong Gwang Cho Jong Chun Park Jung Chaee Kang 田玉敬(译) | 2017 | 首都食品与医药2017，24，22： | 0 |
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