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| 1 | Solutions for submucosal injection: What to choose and how to do it显示文摘During the past decades, endoscopic resection techniques have gradually improved and gained more importance for the management of premalignant lesions and early cancers. These endoscopic resection techniques can be divided in 3 major groups: snare polipectomy, endoscopic mucosal resection(EMR) and endoscopic submucosal dissection(ESD). The use of submucosal injection is essential for the majority of EMR techniques and is an integral part of ESD,whereas during polipectomy it is not crucial in most cases except to prevent bleeding in large polyps and/or those with large stalks as an alternative to mechanical methods. Injection provides a lifting up effect of the lesion separating it from the muscular layer, thereby reducing thermal injury and the risk of perforation and bleeding while also facilitating en-bloc resection by improving technical feasibility. With this work, we aim to review the most common endoscopic resection techniques and the importance of submucosal injection in each one of them. For that, we present some of the most commonly used submucosal injection solutions, taking into account their advantages and disadvantages. We also discuss, based on current recommendations and our own experience, how and when to preform submucosal injection, depending on lesions features and endoscopic resection technique that′s being used, to assure complete resection and to prevent associated adverse events. Finally, we also present and discuss some new proposed submucosal injection solutions,endoscopic resection techniques and devices that may have a major impact on the future of therapeutic endoscopy. | Rui Castro Diogo Libanio Inês Pita Mário Dinis-Ribeiro | 2019 | World Journal of Gastroenterology2019，25，7： | 13 |
| 2 | Prevalence and risk factors of infections by multiresistant bacteria in cirrhosis: A prospective study显示文摘 | Javier Fernández Juan Acevedo Miriam Castro Orlando Garcia Carlos Rodríguez de Lope Daria Roca Marco Pavesi Elsa Sola Leticia Moreira Anibal Silva Tiago Seva‐Pereira Francesco Corradi Jose Mensa Pere Ginès Vicente Arroyo | 2012 | Hepatology2012，，： | 4 |
| 3 | Susceptibility Genetic Variants Associated With Colorectal Cancer Risk Correlate With Cancer Phenotype显示文摘 | Anna Abulí Xavier Bessa Juan Ramón González Clara Ruiz–Ponte Alejandro Cáceres Jenifer Mu?oz Victoria Gonzalo Francesc Balaguer Ceres Fernández–Rozadilla Dolors González Luisa de Castro Juan Clofent Luís Bujanda Joaquín Cubiella Josep M a Re?é Juan Diego | 2010 | Gastroenterology2010，，3： | 2 |
| 4 | Comparison of Effectiveness of Right Ventricular Septal Pacing Versus Right Ventricular Apical Pacing显示文摘 | Oscar Cano Joaquín Osca María-José Sancho-Tello Juan M. Sánchez Víctor Ortiz José E. Castro Antonio Salvador José Olagüe | 2010 | The American Journal of Cardiology2010，，10： | 2 |
| 5 | Effect of a highly concentrated lipopeptide extract of Bacillus subtilis on fungal and bacterial cells 显示文摘 | Etchegaray A de Castro Bueno C de Melo I S | 2008 | Archives of Microbiology2008，190，2： | 1 |
| 6 | Left ventricular remodelling index (LVRI) in various pathophysiological conditions: a real-time three-dimensional echocardiographic study 显示文摘 | De Castro S Caselli S Maron M | 2007 | Heart2007，93，2： | 1 |
| 7 | Carbon nanotubes/poly (e- caprolactone) composite vapour sensors显示文摘 | Castro M Lu J Bruzaud S | 2009 | Carbon2009，47，8： | 1 |
| 8 | New oxidation catalysts based on iron(III) porphyrins immobilized on Mg-Al layered double hydroxides modified with triethanolamine 显示文摘 | CASTRO K A D F BAIL A GROSZEWICZ P B MACHADO G S SCHREINER W H WYPYCH F NAKAGAKI S | 2010 | Appl Catal A: Gen2010，386，： | 1 |
| 9 | Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins显示文摘 | Sangfelt O Erickson S Castro J | 1999 | Oncogene1999，18，18： | 1 |
| 10 | Structural, morphological and surface properties as a function of composition of Ru + Ti + Pt mixed-oxided electrodes 显示文摘 | LASSALI T A F CASTRO S C D BOODTS J F C | 1998 | Electrochimica Acta1998，43，1617： | 1 |
| 11 | Symmetry of Below-ground Competition Between Kochia Scoparia Individuals 显示文摘 | Weiner J Wright D B Castro S | 1997 | Oikos1997，，79： | 1 |
| 12 | Pathogenic variation a- mong isolates of Pyrlcularia grisea infecting rice,wheat and grasses in Brazil显示文摘 | Prabhu A S Filippi M C Castro N | 1992 | Trop Pest Manage1992，38，： | 1 |
| 13 | Effects of levosimendan on systemic and regional hemodynamics in septic myocar-dial depression 显示文摘 | Mo relli A De Castro S Teboul JL | 2005 | Intens Care Med2005，31，5： | 1 |
| 14 | Propolis: recent advances in chemistry and plant origin显示文摘 | BANKOVA V S DE CASTRO S L MARCUCI M C | 2000 | Apidologie2000，31，： | 1 |
| 15 | PROSITE,aprotein domain database for functional characterization and anno-tation显示文摘 | S IGRIST C J A CERUTTI L de CASTRO E | 2010 | Nucleic Acids Research2010，38，1： | 1 |
| 16 | Perturbation of membrane dynamics in nerve cells as an early event during bilirubin-induced apoptosis 显示文摘 | RODRIGUES C M SOLA S CASTRO R E | 2002 | J Lipid Res2002，43，6： | 1 |
| 17 | CFL1 expression levels as a prognostic and drug resistance marker in nonsmall cell lung cancer显示文摘 | Castro MA Dal-Pizzol F Zdanov S | 2010 | Cancer2010，116，： | 1 |
| 18 | The roles of cells and cytokines in the pathogenesis of psoriasis 显示文摘 | Coimbra S Figueiredo A Castro E | 2012 | Int J Dermatol2012，51，4： | 1 |
| 19 | Leucocytoclastic vasculitis associated with golimumab 显示文摘 | pAMIES A CASTRO S POVEDA MJ | 2013 | Rheumatology (Oxford)2013，52，10： | 1 |
| 20 | Updated guidelines for using interferon gamma release assays to detect Mycobacterium turculosis infectiorUnited States, 2010 显示文摘 | Mazurek GH Jereb J Vernon A LoBue P Goldberg S Castro K IGRA Expert Committee Centers for Disease Control and Prevention (CDC) | 2010 | MMWR Recomm Rep2010，59，5： | 1 |
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