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| 1 | Targeted next‐generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas显示文摘 | Eliana Amato Marco dal Molin Andrea Mafficini Jun Yu Giuseppe Malleo Borislav Rusev Matteo Fassan Davide Antonello Yoshihiko Sadakari Paola Castelli Giuseppe Zamboni Anirban Maitra Roberto Salvia Ralph H Hruban Claudio Bassi Paola Capelli Rita T Lawlor Mi | 2014 | J. Pathol2014，，3： | 2 |
| 2 | Characterisation of a microwave induced plasma torch for glass surface modification显示文摘Microwave induced plasma torches find wide applications in material and chemical analysis.Investigation of a coaxial electrode microwave induced plasma(CE–MIP)torch is conducted in this study,making it available for glass surface modification and polishing.A dedicated nozzle is designed to inject secondary gases into the main plasma jet.This study details the adaptation of a characterisation process for CE–MIP technology.Microwave spectrum analysis is used to create a polar plot of the microwave energy being emitted from the coaxial electrode,where the microwave energy couples with the gas to generate the plasma jet.Optical emission spectroscopy analysis is also employed to create spatial maps of the photonic intensity distribution within the plasma jet when different additional gases are injected into it.The CE–MIP torch is experimentally tested for surface energy modification on glass where it creates a super-hydrophilic surface. | Adam BENNETT Nan YU Fengzhou FANG Marco CASTELLI Guoda CHEN Alessio BALLERI Takuya URAYAMA | 2021 | Frontiers of Mechanical Engineering2021，16，1： | 2 |
| 3 | Novel Approaches for Preventing or Limiting Events (Naples) II Trial显示文摘 | Carlo Briguori Gabriella Visconti Amelia Focaccio Bruno Golia Alaide Chieffo Alfredo Castelli Marco Mussardo Matteo Montorfano Bruno Ricciardelli Antonio Colombo | 2009 | Journal of the American College of Cardiology2009，，23： | 2 |
| 4 | Design of a motorised plasma delivery system for ultra-precision large optical fabrication显示文摘A unique plasma figuring(PF)process was created and demonstrated at Cranfield University for manufacturing extremely large telescopes.The atmospheric pressure processing is faster and more cost-effective than other finishing processes;thus,providing an important alternative for large optical surfaces.The industrial scale manufacturing of thousands of ultra-precision metre-scale optics requires a robust PF machine:this requirement is achieved by making the plasma delivery system(PDS)performance repeatable.In this study,a dedicated PDS for large optical manufacturing was proposed to meet the industrial requirement.The PDS is based on an L-type radiofrequency(RF)network,a power supply,and an inductively coupled plasma torch.However,the complexities of these technologies require an in depth understanding of the integrated components that from the PDS.A smart control system for the modified PDS was created.This novel control system aims to make the characterization process deterministic:by automating the tuning of critical electrical components in the RF network,which is achieved by the use of in-line metrology.This paper describes the main design aspects.The PDS was tested with a good correlation between capacitance and RF frequencies.The robust PDS design enables a stable discharge of plasma with a low deviation of RF signals during the total15 hours’test. | Hui Zhou Adam Bennett Marco Castelli Renaud Jourdain Jiang Guo Nan Yu | 2020 | International Journal of Extreme Manufacturing2020，2，4： | 2 |
| 5 | Numerical evaluation of aerodynamic and inertial contributions to Darrieus wind turbine blade deformation显示文摘 | MARCO RACITI CASTELLI ANDREA DAL MONTE MARINO QUARESIMIN | | 0，，： | 1 |
| 6 | The Darrieus wind turbine: Proposal for a new performance prediction model based on CFD显示文摘 | Castelli Marco Raciti Englaro Alessandro Benini Ernesto | 2011 | Energy2011，36，8： | 1 |
| 7 | Unique immunological profile in patients with COVID-19显示文摘The relationship between severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)and host immunity is poorly understood.We performed an extensive analysis of immune responses in 32 patients with severe COVID-19,some of whom succumbed A control population of healthy subjects was included.Patients with COVID-19 had an altered distribution of peripheral blood lymphocytes,with an increased proportion of mature natural killer(NK)cells and low T-cell numbers.NK cells and CD8^(+)T cells overexpressed T-cellimmunoglobulin and mucin domain-3(TIM-3)and CD69.NK cell exhaustion was attested by increased frequencies of programmed cell death protein 1(PD-1)positive cells and reduced frequencies of natural killer group 2 member D(NKG2D)-,DNAX accessory molecule-1(DNAM-1)-and sialic acid-binding Ig-like lectin 7(Siglec-7)-expressing NK cells,associated with a reduced ability to secrete interferon(IFN)γ.Patients with poor outcome showed a contraction of immature CD56^(bright) and an expansion of mature CD57^(+)F_(CEI)Rlγ^(eng) adaptive NK cells compared to survivors.Increased serum levels of IL-6 were also more frequently identified in deceased patients compared to survivors.Of note,monocytes secreted abundant quantities of IL-6,IL-8,and IL-1β which persisted at lower levels several weeks after recovery with concomitant normalization of CD69,PD-1 and TIM-3 expression and restoration of CD8^(+)T cell numbers.A hyperactivated/exhausted immune response dominate in severe SARS-CoV-2 infection,probably driven by an uncontrolled secretion of inflammatory cytokines by monocytes.These findings unveil a unique immunological profile in COVID-19 patients that will help to design effective stage-specific treatments for this potentially deadly disease. | Stefania Varchetta Dalila Mele Barbara Olivier Stefania Mantovani Serena Ludovisi Antonella Cerino Raffaele Bruno Alberto Castelli Mario Mosconi Marco Vecchia Silvia Roda Michele Sachs Catherine Klersy Mario U.Mondelli | 2021 | Cellular & Molecular Immunology2021，18，3： | 1 |
| 8 | Investigation of a plasma delivery system for optical figuring process显示文摘Plasma figuring process enables the correction of metre-scale optical surfaces,which has advantages such as rapid convergence to ultra-precision accuracy level,no subsurface damage,ease of upscale thanks to the conditions of operation at atmospheric.Such attributes make plasma figuring a highly competitive technology.To maintain a stable discharge of plasma for long period,a robust Plasma Delivery System(PDS)is required for large optics manufacturing.A dedicated PDS,mainly based on an L-type radio frequency(RF)network and an inductively coupled plasma(ICP)torch,had been previously proposed and designed.This study addresses the requirement for improving the robustness and securing the performance of the plasma etching.Due to the complexity of interactions of PDS parameters,single variable optimization is conducted for adjusting the impedance of the plasma torch.The PDS optimization is analysed based on ignition power demand,test repeatability and reflected power values.The results show that reflected power values are controllable within 10 W,when the RF power is supplied from 200 W up to 800 W.Finally,plasma processing is carried out on fused silica glass,using the optimum parameters of the PDS. | Nan YU Renaud JOURDAIN Marco CASTELLI Adam BENNETT Jiang GUO Chengyu MA Fengzhou FANG | 2021 | Chinese Journal of Aeronautics2021，34，4： | 1 |
| 9 | Impairment of mitochondrial oxidative phosphorylation in rat fatty liver exposed to preservation-reperfusion injury显示文摘 | Paolo Caraceni Cristina Bianchi Marco Domenicali Anna Maria Pertosa Elisabetta Maiolini Giovanna Parenti Castelli Bruno Nardo Franco Trevisani Giorgio Lenaz Mauro Bernardi | 2004 | Journal of Hepatology2004，，1： | 1 |
| 10 | Reactive atom plasma for rapid figure correction of optical surfaces显示文摘 | Castelli Marco Jourdain Renaud Morantz Paul | 2012 | Key Engineering Materials2012，96，： | 1 |
| 11 | Catastrophe analysis of a planar system with flexural pivots显示文摘 | Marco C Duffy J Castelli V P | 2002 | Mecha- nism and Machine Theory2002，37，： | 1 |
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