|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Combined carriership of TLR9 -1237C and CD14 -260T alleles enhances the risk of developing chronic relapsing pouchitis显示文摘AIM: To investigate the single nucleotide polymorphisms (SNPs) in genes involved in bacterial recognition and the susceptibility to pouchitis or pouchitis severity.METHODS: Analyses of CD14 -260C>T, CARD15/NOD2 3020insC, Toll-like receptor (TLR)4 +896A>G,TLR9 -1237T>C, TLR9+ 2848G>A, and IRAKM +22148G>A SNPs were performed in 157 ileal-pouch anal anastomosis (IPAA) patients (79 patients who did not develop pouchitis, 43 infrequent pouchitis patients,35 chronic relapsing pouchitis patients) and 224 Italian Caucasian healthy controls.RESULTS: No significant differences were found in SNP frequencies between controls and IPAA patients.However, a significant difference in carriership frequency of the TLR9-1237C allele was found between the infrequent pouchitis and chronic relapsing pouchitis groups [P = 0.028, odd's ratio (OR) = 3.2, 95%CI = 1.2-8.6].This allele uniquely represented a 4-locus TLR9 haplotype comprising both studied TLR9 SNPs in Caucasians.Carrier trait analysis revealed an enhanced combined carriership of the alleles TLR9 -1237C and CD14 -260T in the chronic relapsing pouchitis and infrequent pouchitis group (P = 0.018, OR = 4.1, 95%CI = 1.4 -12.3).CONCLUSION: There is no evidence that the SNPs predispose to the need for IPAA surgery. The significant increase of the combined carriership of the CD14 -260T and TLR9 -1237C alleles in the chronic relapsing pouchitis group suggests that these markers identify a subgroup of IPAA patients with a risk of developing chronic or refractory pouchitis. | KM Lammers S Ouburg SA Morré JBA Crusius P Gionchetti F Rizzello C Morselli E Caramelli R Conte G Poggioli M Campieri AS Pea | 2005 | World Journal of Gastroenterology2005，11，46： | 7 |
| 2 | Numerical investigation of forced fluid flow and heat transfer from conically coiled pipes显示文摘 | CONTE I PENG X F WANG B X | 2008 | Nume Heat Transfer A Appl2008，53，9： | 1 |
| 3 | Thirty years ofgraph matching in pattern recognition显示文摘 | CONTE D F()GGIA P SANSONE C | 2004 | International Jour-nal of Pattern Recognition and Artificial Intelligence2004，18，3： | 1 |
| 4 | Identification of novel RP2 mutations in a subset of X-linked retilfitis pigmentosa families and prediction of new domains 显示文摘 | Miano MG Testa F Filippini F Trujifio M Conte I Lanzara C | 2001 | Hum Murat2001，18，2： | 1 |
| 5 | Cardiovascular disease in chronic renal failure: The challenge continues显示文摘 | Locatelli F Marcelli D Conte F | 2000 | Nephrol Dial Transplant2000，15，： | 1 |
| 6 | Pediatric endocrinology update : an overview 显示文摘 | Mac Gillivray MH Morishima A Conte F | 1998 | Horm Res1998，49，1： | 1 |
| 7 | Severe coronary artery disease after radiation therapy of the chest and mediastinum: clinical presentation and treatment 显示文摘 | ORZAN F BRUSCA A CONTE M R | 1993 | Br Heart J1993，69，6： | 1 |
| 8 | Successful phacoemulsification in vitrectomized eyes : technical considerations 显示文摘 | Rouhette H Conte M Guillemot F | 2014 | J Fr Ophtalmol2014，37，3： | 1 |
| 9 | Survivin expression in chronic myeloid leukemia显示文摘 | CONTE E STAGNO F GUGLIELMO P | 2005 | Cancer Lett2005，225，1： | 1 |
| 10 | Parathyroidectomy in patients on renal replacement therapy: an epidemiologic study显示文摘 | Malberti F Marcelli D Conte F | 2001 | J Am Soc Nephrol2001，12，6： | 1 |
| 11 | Modal identification study of vincent thomas bridge using simulated wind-induced ambient vibration data 显示文摘 | He X F Babak M Conte J P | 2008 | Computer-Aided Civil and Infrastructure Engineering2008，23，： | 1 |
| 12 | Close relation between cirrhosis and gallstone: cross sectional and longitudinal survey显示文摘 | Conte D Fragucelli M Fornari F | 1999 | Arch Intern Med1999，159，1： | 1 |
| 13 | Polycyclic aromatic hydrocarbons in farmed rainbow trout (Oncorhynchus mykiss) processed by traditional flue gas smoking and by liquid smoke flavorings显示文摘 | VISCIANO P PERUGINI M CONTE F | 2008 | Food and Chemical Toxicology2008，46，5： | 1 |
| 14 | Stability analysis of slopes in soils with strain-softening behavior显示文摘 | Conte E Silvestri F Troncone A | 2010 | Computers and Geotechnics2010，37，5： | 1 |
| 15 | Micro-beamer based on MEMS micro-mirrors and laser light source 显示文摘 | Winter C Fabre L Conte F Lo | 2009 | Proeedia Chemistry(S1876-6196)2009，1，1： | 1 |
| 16 | Economic Growth and the Expanding Public Sector: A Reexamination显示文摘 | Conte M A A F Darrar | 1988 | The Review of Economics and Statistics1988，70，2： | 1 |
| 17 | Stress and the welfare of cultured fish 显示文摘 | Conte F S | 2004 | Applied Animal Behaviour Science2004，86，34： | 1 |
| 18 | Phosphorylation of the TGBpl movement protein of Potato virus X by a Nicotiana tabacum CK2-like activity显示文摘 | Modena N A Zelada A M Conte F | 2008 | Virus Res2008，137，1： | 1 |
| 19 | Metal catalysis in oxidation by peroxides, electrophilic oxygen transfer from anionic, coordinatively saturated molybdenum peroxo complexes显示文摘 | CAMPESTRINI S CONTE V FURIA F D | 1988 | Org Chem1988，53，： | 1 |
| 20 | Survival and development of cardiovascular disease by modality of treatment in patients with endstage renal disease显示文摘 | Locatelli F Marcelli D Conte F | 2001 | J Am Soc Nephrol2001，12，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员