|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Spinal Cord Stimulation for Pain Treatment After Spinal Cord Injury显示文摘In addition to restoration of bladder, bowel, and motor functions, alleviating the accompanying debilitating pain is equally important for improving the quality of life of patients with spinal cord injury(SCI). Currently,however, the treatment of chronic pain after SCI remains a largely unmet need. Electrical spinal cord stimulation(SCS) has been used to manage a variety of chronic pain conditions that are refractory to pharmacotherapy. Yet, its efficacy, benefit profiles, and mechanisms of action in SCI pain remain elusive, due to limited research, methodological weaknesses in previous clinical studies, and a lack of mechanistic exploration of SCS for SCI pain control. We aim to review recent studies and outline the therapeutic potential of different SCS paradigms for traumatic SCI pain. We begin with an overview of its manifestations,classification, potential underlying etiology, and currentchallenges for its treatment. The clinical evidence for using SCS in SCI pain is then reviewed. Finally, future perspectives of pre-clinical research and clinical study of SCS for SCI pain treatment are discussed. | Qian Huang Wanru Duan Eellan Sivanesan Shuguang Liu Fei Yang Zhiyong Chen Neil C.Ford Xueming Chen Yun Guan | 2019 | Neuroscience Bulletin2019，35，3： | 13 |
| 2 | Epidemiology of Helicobacter pylori infection and Public Health Implications显示文摘 | Alexander C.Ford Anthony T. R.Axon | 2010 | Helicobacter2010，，： | 4 |
| 3 | Synthesis,Contact Printing,and Device Characterization of Ni-Catalyzed,Crystalline InAs Nanowires显示文摘InAs nanowires have been actively explored as the channel material for high performance transistors owing to their high electron mobility and ease of ohmic metal contact formation.The catalytic growth of nonepitaxial InAs nanowires,however,has often relied on the use of Au colloids which is non-CMOS compatible.Here,we demonstrate the successful synthesis of crystalline InAs nanowires with high yield and tunable diameters by using Ni nanoparticles as the catalyst material on amorphous SiO_(2) substrates.The nanowires show superb electrical properties with field-effect electron mobility~2700 cm^(2)/Vs and ION/IOFF>10^(3).The uniformity and purity of the grown InAs nanowires are further demonstrated by large-scale assembly of parallel arrays of nanowires on substrates via the contact printing process that enables high performance,“printable”transistors,capable of delivering 510 mA ON currents(~400 nanowires). | Alexandra C.Ford Johnny C.Ho Zhiyong Fan Onur Ergen Virginia Altoe Shaul Aloni Haleh Razavi Ali Javey | 2008 | Nano Research2008，1，1： | 3 |
| 4 | Systematic review: granulocyte/monocyte adsorptive apheresis for ulcerative colitis显示文摘 | S.Thanaraj P. J.Hamlin A. C.Ford | 2010 | Alimentary Pharmacology & Therapeutics . 2010 (11‐)2010，，11： | 1 |
| 5 | Generation of Transgene‐Free Lung Disease‐Specific Human Induced Pluripotent Stem Cells Using a Single Excisable Lentiviral Stem Cell Cassette显示文摘 | AbaSomers Jyh‐ChangJean Cesar A.Sommer AmelOmari Christopher C.Ford Jason A.Mills LeiYing Andreia GianottiSommer Jenny M.Jean Brenden W.Smith RobertLafyatis Marie‐FranceDemierre Daniel J.Weiss Deborah L.French PaulGadue George J.Murphy GustavoMostoslavsky | 2010 | STEM CELLS2010，，10： | 1 |
| 6 | Detecting white matter alterations in multiple sclerosis using advanced diffusion magnetic resonance imaging显示文摘Multiple sclerosis is a neurodegenerative and inflammatory disease, a hallmark of which is demyelinating lesions in the white matter. We hypothesized that alterations in white matter microstructures can be non-invasively characterized by advanced diffusion magnetic resonance imaging. Seven diffusion metrics were extracted from hybrid diffusion imaging acquisitions via classic diffusion tensor imaging, neurite orientation dispersion and density imaging, and q-space imaging. We investigated the sensitivity of the diffusion metrics in 36 sets of regions of interest in the brain white matter of six female patients(age 52.8 ± 4.3 years) with multiple sclerosis. Each region of interest set included a conventional T2-defined lesion, a matched perilesion area, and normal-appearing white matter. Six patients with multiple sclerosis(n = 5) or clinically isolated syndrome(n = 1) at a mild to moderate disability level were recruited. The patients exhibited microstructural alterations from normal-appearing white matter transitioning to perilesion areas and lesions, consistent with decreased tissue restriction, decreased axonal density, and increased classic diffusion tensor imaging diffusivity. The findings suggest that diffusion compartment modeling and q-spa ce analysis appeared to be sensitive for detecting subtle microstructural alterations between perilesion areas and normal-appearing white matter. | Sourajit M.Mustafi Jaroslaw Harezlak Chandana Kodiweera Jennifer S.Randolph James C.Ford Heather A.Wishart Yu-Chien Wu | 2019 | Neural Regeneration Research2019，14，1： | 1 |
| 7 | Wavelet basis reconstruction of nonuniformly sampled data显示文摘 | C.Ford D.M.Etter | 1998 | IEEE Transactions Circuits and System II:Analog and Digital Signal Processing1998，，08： | 1 |
| 8 | Why buy what you can get for free? The effect of foreign direct investment on state patent rates显示文摘 | Timothy C.Ford a Jonathan C.Rork | | 0，，： | 1 |
| 9 | Epidemiology of Helicobacter pylori infection and Public Health Implications显示文摘 | Alexander C.Ford Anthony T. R.Axon | 2010 | Helicobacter2010，，： | 1 |
| 10 | Mechanisms of bone pain:Progress in research from bench to bedside显示文摘The field of research on pain originating from various bone diseases is expanding rapidly, with new mechanisms and targets asserting both peripheral and central sites of action. The scope of research is broadening from bone biology to neuroscience,neuroendocrinology, and immunology. In particular, the roles of primary sensory neurons and non-neuronal cells in the peripheral tissues as important targets for bone pain treatment are under extensive investigation in both pre-clinical and clinical settings. An understanding of the peripheral mechanisms underlying pain conditions associated with various bone diseases will aid in the appropriate application and development of optimal strategies for not only managing bone pain symptoms but also improving bone repairing and remodeling, which potentially cures the underlying etiology for long-term functional recovery. In this review, we focus on advances in important preclinical studies of significant bone pain conditions in the past 5 years that indicated new peripheral neuronal and non-neuronal mechanisms, novel targets for potential clinical interventions, and future directions of research. | Gehua Zhen Yuhan Fu Chi Zhang Neil C.Ford Xiaojun Wu Qichao Wu Dong Yan Xueming Chen Xu Cao Yun Guan | 2022 | Bone Research2022，10，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员