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| 1 | Percutaneous electrochemotherapy in the treatment of portal vein tumor thrombosis at hepatic hilum in patients with hepatocellular carcinoma in cirrhosis: A feasibility study显示文摘AIM To treated with electrochemotherapy(ECT) a prospective case series of patients with liver cirrhosis and Vp3-Vp4- portal vein tumor thrombus(PVTT) from hepatocellular carcinoma(HCC), in order to evaluate the feasibility, safety and efficacy of this new non thermal ablative technique in those patients. METHODS Six patients(5 males and 1 female), aged 61-85 years(mean age, 70 years), four in Child-Pugh A and two in Child-Pugh B class, entered our study series. All patients were studied with three-phase computed tomography(CT), contrast enhanced ultrasound(CEUS) and ultrasound-guided percutaneous biopsy of the thrombus before ECT. All patients underwent ECT treatment(Cliniporator Vitae?, IGEA Sp A, Carpi, Modena, Italy) of Vp3-Vp4 PVTT in a single session. At the end of the procedure a post-treatment biopsy of the thrombus was performed. Scheduled follow-up in all patients entailed: CEUS within 24 h after treatment; triphasic contrastenhanced CT and CEUS at 3 mo after treatment and every six months thereafter.RESULTS Post-treatment CEUS showed complete absence of enhancement of the treated thrombus in all cases. Post-treatment biopsy showed apoptosis and necrosis of tumor cells in all cases. The follow-up ranged from 9 to 20 mo(median, 14 mo). In 2 patients, the followup CT and CEUS demonstrated complete patency of the treated portal vein. Other 3 patients showed a persistent avascular non-tumoral shrinked thrombus at CEUS and CT during follow-up. No local recurrence was observed at follow-up CT and CEUS in 5/6 patients. One patient was lost to follow-up because of death from gastrointestinal hemorrage 5 wk after ECT. CONCLUSION In patients with cirrhosis, ECT seems effective and safe for curative treatment of Vp3-Vp4 PVTT from HCC. | Luciano Tarantino Giuseppina Busto Aurelio Nasto Raffaele Fristachi Luigi Cacace Maria Talamo Catello Accardo Sara Bortone Paolo Gallo Paolo Tarantino Riccardo Aurelio Nasto Matteo Nicola Dario Di Minno Pasquale Ambrosino | 2017 | World Journal of Gastroenterology2017，23，5： | 7 |
| 2 | World Gastroenterology Organisation Global Guideline: Constipation—A Global Perspective显示文摘 | Greger Lindberg Saeed S. Hamid Peter Malfertheiner Ole Ostergaard Thomsen Luis Bustos Fernandez James Garisch Alan Thomson Khean-Lee Goh Rakesh Tandon Suliman Fedail Benjamin C.Y. Wong Aamir Ghafoor Khan Justus H. Krabshuis Anton LeMair | 2011 | Journal of Clinical Gastroenterology2011，，6： | 3 |
| 3 | Concurrent measurement of (Na+,K+)-ATPase activity and lipid peroxides in rat brain following reversible global ischemia显示文摘 | William J. Goldberg Brant D. Watson Raul Busto Harry Kurchner Mercedes Santiso Myron D. Ginsberg | 1984 | Neurochemical Research1984，，12： | 2 |
| 4 | A comparison of methods for sketch-based 3D shape retrieval显示文摘 | Bo Li Yijuan Lu Afzal Godil Tobias Schreck Benjamin Bustos Alfredo Ferreira Takahiko Furuya Manuel J. Fonseca Henry Johan Takahiro Matsuda Ryutarou Ohbuchi Pedro B. Pascoal Jose M. Saavedra | 2014 | Computer Vision and Image Understanding2014，，： | 2 |
| 5 | Comparative effect of transient global ischemia on extracellular levels of glutamate,glycine and gamma-aminobutyric acid in vulnerable and nonvulnerable brain regions in the rat显示文摘 | Globus MY Busto R Martinez E | 1991 | J Neurechem1991，5，： | 2 |
| 6 | Molecular characterisation of the inactive allele of the gene Glu-A1 and the development of a set of AS-PCR markers for HMW glutenins of wheat显示文摘 | A. De Bustos P. Rubio N. Jouve | 2000 | TAG Theoretical and Applied Genetics2000，，7： | 2 |
| 7 | Mutations of PVRL1, encoding a cell-cell adhesion molecule/herpesvirus receptor, in cleft lip/palateectodermal dysplasia 显示文摘 | Suzuki K Hu D Bustos T | 2000 | Nat Genet2000，25，4： | 1 |
| 8 | Small diffemnces in-tntlschemlc brain temperature critically determine the extent of is-chemic neuronal injury显示文摘 | Dietrich WD Globus M | 1987 | J Cereb Blood Flow Metab1987，7，： | 1 |
| 9 | Combating Hyperthermia in Acute Stroke:A Significant Clinical Concern显示文摘 | BUSTO R | 1998 | Stroke(S0039-2499)1998，29，2： | 1 |
| 10 | Intraischemic but not postischemic brain hypothermia protects chronically following global forebrain ischemia in rats显示文摘 | Dietrich WD Busto R Alonso O | 1993 | J Cereb Blood Flow Metab1993，13，4： | 1 |
| 11 | Multiple route and dose pharmacokinetics of enrofloxaein in juvenile Atlantic salmon 显示文摘 | Stoffregen D A Wooster G A Bustos P S | 1997 | J Vet Pharmaeol Therap1997，20，： | 1 |
| 12 | Pain management after major orthopaedic surgery:Current strategies and new con- cepts 显示文摘 | Sinatra RS Tortes J Bustos AM | 2002 | J Am Acad Orthop Surg2002，10，： | 1 |
| 13 | Grape-seed procyanidins prevent low-grade inflammation by modulating cyto- kine expression in rats fed a high-fat diet显示文摘 | Ximena Terra Gemma Montagut Mario Bustos | 2009 | Journal of Nutritional Biochemistry2009，20，： | 1 |
| 14 | Genetic profiles of longevityand healthy cognitive aging in nonagenarians from the Basquecountry显示文摘 | Martín XE Busto FG Artabe IA | 2011 | Rev Esp Geriatr Gerontol2011，46，4： | 1 |
| 15 | Regional alteration of protein kinase C activity following transient cerebral ischemia:effects of intraischemia brain temperature modulation显示文摘 | Busto R Globus MY Neary JT | 1994 | J Neurochem1994，63，3： | 1 |
| 16 | Atorvastatin reduces NF-κB activation and chemokine expression in vascular smooth cells and mononuclear cells显示文摘 | Monica Qrtego Carmen Bustos Miguel A | 1999 | Atherosclerosis1999，147，： | 1 |
| 17 | Middle cerebral artery occlusion in the rat by intraluminal suture显示文摘 | Belayev L Alonso OF Busto R | 1996 | Stroke1996，27，9： | 1 |
| 18 | Small differences in intraischemic Brain temperature critically determined the extent of ischemia neuronal in jury显示文摘 | Busto R Dietrich WP Globus MY | 1987 | Cereb Blood Flow Metab1987，7，6： | 1 |
| 19 | Effect of delayed albumin hemod-ilution on infarction volume and brain edema after transient middle cerebral artery occlusion in rats 显示文摘 | Belayev L Busto R Zhao W | 1997 | J Neurosurg1997，87，： | 1 |
| 20 | Purification of trypsin- like enzymes from Antarctic krill processing wastewater显示文摘 | BUSTOS R O ROMO C R HEALY M | 1999 | Process Biochemistry1999，35，3： | 1 |
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