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| 1 | 正常人左心室功能指标的参考值及其预计公式的初步研究报告显示文摘目的:当前评估左心室容量和功能仍常用正常值范围,个体化分析也仅使用体表面积进行校正。尚缺少个体化因素相关的大样本参考值和预计公式。方法:本研究纳入美国加州洛杉矶县南湾地区1200名健康志愿者,其中男807女393,年龄20岁-94岁,心脏CT造影(CTA),经过高精度三维成像技术处理,计算左心室容积在收缩和舒张过程中的连续动态变化,测定左心室(LV)容量和功能指标:舒张末期容积(EDV)、收缩末期容积(ESV)、每搏输出量(SV)、射血分数(EF)和心输出量(CO)。将以上指标与一般特征指标进行多因素相关分析,以探索正常人预计值计算公式。结果:男性除LVEF小于女性外(P<0.001),其余各指标均大于女性(P<0.001)。多元线性回归分析提示,性别、年龄、身高和体质量均为EDV、ESV、SV的独立影响因子(P<0.001);而CO仅受年龄、性别、体质量显著影响(P<0.001),但与身高无关(P>0.05)。CO的预测公式CO(L·min-1)=6.963+0.446(Male)-0.037×年龄(yr)+0.013×体质量(kg)。结论:性别、年龄、身高、体质量均影响左心室容量和功能,建立预测值计算公式,对心血管疾病的无创评估和个体化精准医疗具有重要参考价值。 | 卢志南 孙兴国 Songshou Mao Matthew J. Budoff William W. Stringer 葛万刚 李浩 黄洁 刘方 胡盛寿 | 2015 | 中国应用生理学杂志2015，31，4： | 6 |
| 2 | NAFLD prevalence differs among hispanic subgroups:The multi-ethnic study of atherosclerosis显示文摘AIM:To compare prevalence rates of non-alcoholic fatty liver disease(NAFLD)between Hispanics of Mexican origin and Hispanics of Dominican and Puerto Rican origin.METHODS:We evaluated prevalence rates of NAFLD between the two largest sub-populations of Hispanics in the United States;Hispanics of Mexican origin and Hispanics of Caribbean origin(Dominican and Puerto Rican),in the multi-ethnic study of atherosclerosis(MESA)cohort.MESA is a large,population based,multi-center cohort study comprised of 6814 healthy Caucasian,African-American,Hispanic,and Asian men and women aged 45-84.We utilized the baseline serum,anthropometric and radiographic measurements obtained between 2000 and 2002.NAFLD was measured via computed tomography scan and was defined as liver/spleen attenuation ratio<1.RESULTS:There were 788 Hispanic participants included in the study after exclusions.The prevalence of NAFLD was 29%(n=225).Hispanics of Mexican origin had a significantly higher prevalence of NAFLD(33%),compared to Hispanics of Dominican origin(16%),(P<0.01)and Hispanics of Puerto Rican origin(18%),(P<0.01).After controlling for age,sex,BMI,waist circumference,hypertension,serum HDL,triglyceride and CRP level and insulin resistance,Hispanics of Mexican origin remained significantly more likely to have NAFLD than those of Dominican and Puerto Rican origin.CONCLUSION:United States Hispanics of Mexican origin have a significantly higher prevalence of NAFLD when compared to United States Hispanics of Dominican or Puerto Rican origin after controlling for known risk factors.Care should be taken when performing risk assessment in Hispanic populations not to make assumptions of homogeneity. | Michael Wayne Fleischman Matthew Budoff Ifran Zeb Dong Li Temitope Foster | 2014 | World Journal of Gastroenterology2014，20，17： | 5 |
| 3 | Metabolic syndrome and coronary artery calcification: a community-based natural population study显示文摘 | CAO Hui-li CHEN Xiong-biao LU Jin-guo HOU Zhi-hui TANG Xiang GAO Yang YU Fang-fang JIANG Shi-liang ZHAO Lian-cheng LI Ying Matthew J Budoff Robert Detrano LU Bin | 2013 | Chinese Medical Journal2013，，24： | 4 |
| 4 | 建立正常人肺血管容量的无创精确测量方法的初步报告显示文摘目的:由于传统呼吸调控环路忽略了对血液循环的决定性作用,肺(静脉)血管容量相关研究甚少,亟需建立肺血管容量测量方法。方法:选择正常志愿者完成CT全肺扫描,图像数据经过计算机软件分析处理,从肺尖到肺底以40~50层进行肺野手工切划,相邻层间由计算机自动模拟连接,在去除干扰后进行全肺血管(≥0.6 mm)高精度三维立体成像技术处理,进而计算全肺和肺血管容积。结果:12例正常志愿者从肺尖到肺底CT扫描图片层数为530±98(431~841)张。全肺和肺血管的总容积是3705±857(2398~5383)ml,肺血管血液总的容积是125±32(94~201)ml。按肺静脉系统血管容量约为全肺血管血液容量一半计算,应该是63±16(47~100)ml。结论:肺CT扫描数据分析三维立体成像建立肺血管容量无创测量方法精确可行。 | 孙兴国 Songshou Mao Matthew J. Budoff William W. Stringer 程显声 | 2015 | 中国应用生理学杂志2015，31，4： | 4 |
| 5 | 在有症状的患者中,与传统危险因素相比,冠状动脉钙化积分能更准确地预测显著的冠状动脉狭窄:欧洲钙化性冠状动脉疾病研究显示文摘在这项回顾性研究中,研究人员评估了冠状动脉钙化积分相对于传统危险因素对显著狭窄(冠状动脉狭窄〉50%)的预测价值。方法与结果:纳入来自丹麦、法国、德国、意大利、西班牙和美国有症状的患者5515例,所有研究对象均进行危险因素评估、计算机断层冠状动脉造影(computed tomographic coronary angiogram,CTCA)或常规血管造影。 | 刘莉 叶鹏 Nicoll R Wiklund U Zhao Y Diederichsen A Mickley H Ovrehus K Zamorano P Gueret P Schmermund A Maffei E Cademartiri F Budoff M Henein M | 2016 | 中华高血压杂志2016，24，3： | 4 |
| 6 | 冠状动脉钙化在高血压患者心血管病风险分层中的作用显示文摘研究者研究了冠状动脉钙化(coronary artery calcium,CAC)在成人高血压心血管病风险分层中的作用,包括符合收缩压干预试验(systolic blood pressure intervention trial,SPRINT)标准的患者。此外,研究者使用CAC来确定心血管病死亡率与SPRINT中标准降压组心血管病死亡率('SPRINT水平')相当的高血压成年患者,其可能受益于强化降压治疗。研究人群包括来自CAC研究联盟的高血压患者16 167例,其中6375例患者构成'SPRINT类似人群'。研究者按CAC分类(0,1~99,100~399,≥400)比较了多因素校正后的冠状动脉粥样硬化性心脏病(冠心病)和心血管病死亡风险比。 | 刘青(译) 叶鹏(摘、审校) Uddin SMI Mirbolouk M Kianoush S Orimoloye OA Dardari Z Whelton SP Miedema MD Nasir K Rumberger JA Shaw LJ Berman DS Budoff MJ McEvoy JW Matsushita K Blaha MJ Graham G | 2019 | 中华高血压杂志2019，27，5： | 3 |
| 7 | 农村人口亚临床动脉粥样硬化及其与冠状动脉疾病危险因素的关系显示文摘在美国〈65岁的人群中,包括无症状的个体在内,每年有超过15万的心血管事件发生。冠状动脉钙化(coronary artery calcium,CAC)是冠状动脉疾病(coronary artery disease,CAD)的亚临床指标,可提高无症状个体的危险分层。该研究旨在评估农村人口的CAC发生率,确定CAD传统危险因素和CAC评分之间的相关性。方法:2011年1月至2012年12月,研究人员对来自阿巴拉契亚中部地区无症状个体的CAC情况进行筛查,根据Agatston钙化评分将受试者分为4种CAC水平:无(CAC=0),轻度(CAC=1~99),中度(CAC=100~399)和重度(CAC≥400)。 | 刘莉 叶鹏 Mamudu HM Paul T Veeranki SP Wang L Panchal HB Budoff M | 2015 | 中华高血压杂志2015，23，8： | 3 |
| 8 | Mortality Incidence and the Severity of Coronary Atherosclerosis Assessed by Computed Tomography Angiography显示文摘 | Matthew P. Ostrom Ambarish Gopal Naser Ahmadi Khurram Nasir Eric Yang Ioannis Kakadiaris Ferdinand Flores Song S. Mao Matthew J. Budoff | 2008 | Journal of the American College of Cardiology2008，，16： | 2 |
| 9 | ACCF/ACR/AHA/NASCI/SAIP/SCAI/SCCT 2010 Expert Consensus Document on Coronary Computed Tomographic Angiography显示文摘 | Daniel B. Mark Daniel S. Berman Matthew J. Budoff J. Jeffrey Carr Thomas C. Gerber Harvey S. Hecht Mark A. Hlatky John McB. Hodgson Michael S. Lauer Julie M. Miller Richard L. Morin Debabrata Mukherjee Michael Poon Geoffrey D. Rubin Robert S. Schwartz | 2010 | Journal of the American College of Cardiology2010，，23： | 2 |
| 10 | Nonalcoholic fatty liver disease and serum lipoproteins: The Multi-Ethnic Study of Atherosclerosis显示文摘 | Andrew Paul DeFilippis Michael J. Blaha Seth S. Martin Robert M. Reed Steven R. Jones Khurram Nasir Roger S. Blumenthal Matthew J. Budoff | 2013 | Atherosclerosis2013，，： | 2 |
| 11 | 正常人每搏输出量与肺静脉血管容量和左心房容量的相关关系的探讨显示文摘目的:从新理论对呼吸调控解释中,肺-动脉血液循环时间直接决定了吸、呼时相从开始到被终止(即吸呼切换)时间,从而形成呼吸节律和频率。但相关研究甚少,使用肺CT扫描和心脏CTA造影对同一个人进行肺静脉血管容量、左心房容量及每搏输出量多项测定,分析其相关关系以探讨循环时间对呼吸的调控。方法:按我们近期建立肺CT扫描进行全肺血管(≥0.06 mm)高精度三维立体成像技术处理后,估算肺静脉血管容量和心脏CTA造影数据经过计算机软件分析处理,计算左心房容量和每搏输出量。将三者进行相关关系分析,推算肺-循环时间。结果:5例正常志愿者的全肺和肺血管的总容量3486±783(2156-4418)ml,肺血管容量141±20(105-163)ml,估算肺静脉血管容量71±10(52-81)ml;左心房容量是97±39(53-165)m L,每搏输出量是86±16(60-106)ml。肺静脉血管容量和左心房容量之和大约是每搏输出量2.0±0.3(1.7-2.4)倍;其中肺静脉血管容量略小于每搏输出量(0.8±0.1),而左心房容量略大于每搏输出量(1.1±0.4)。结论 :推算的肺-动脉时间约为三次心跳。 | 孙兴国 Songshou Mao Matthew J. Budoff William W. Stringer 程显声 | 2015 | 中国应用生理学杂志2015，31，4： | 2 |
| 12 | The Prevalence and Clinical Correlates of Nonalcoholic Fatty Liver Disease (NAFLD) in African Americans: The Multiethnic Study of Atherosclerosis (MESA)显示文摘 | Temitope Foster Frank A. Anania Dong Li Ronit Katz Matthew Budoff | 2013 | Digestive Diseases and Sciences2013，，8： | 2 |
| 13 | 冠状动脉钙化用于指导个性化阿司匹林治疗以预防心血管病:基于多民族动脉粥样硬化研究显示文摘最近美国心脏病学会/美国心脏协会(American College of Cardiology/American Heart Association,ACC/AHA)的一级预防指南建议,低剂量阿司匹林治疗仅适用于年龄40~70岁、患动脉粥样硬化性心血管病(atherosclerotic cardiovascular disease,ASCVD)风险较高,但出血风险不高的成年人。然而,尚不清楚如何更准确地识别出这些患者。根据2019年降低心血管病相对危险度和出血风险的阿司匹林荟萃分析研究数据,本研究旨在评估冠状动脉钙化(coronary artery calcium,CAC)在指导阿司匹林在一级预防中如何使用的价值。 | 周卫(译) 叶鹏(摘/审校) Achirica MC Miedema MD McEvoy JW Rifai MA Greenland P Dardari Z Budoff M Blumenthal RS Yeboah J Duprez DA Mortensen MB Dzaye O Hong J Nasir K Blaha MJ | 2020 | 中华高血压杂志2020，28，4： | 2 |
| 14 | Assessment of coronary artery disease by cardiac computed tomography:a scientific statement from the American Heart Association Committee on Cardiovascular Imaging and Intervention,Council on Cardiovascular Radiology and Intervention,and Committee on Cardiac Imaging,Council on Clinical Cardiology显示文摘 | Achenbach S Blumenthal RS | 2006 | Circulation2006，114，16： | 1 |
| 15 | Assessment of Coronary Artery Disease by Cardiac Computed Tomography :A Scientific Statement From the American Heart Association Committee on Cardiovascular Imaging and Intervention, Council on Cardiovascular Radiology and Intervention, and Committee on Cardiac Imaging, Council on Clinical Cardiology显示文摘 | Budoff MJ Achenbach S Blumenthal RS | 2006 | Circulation2006，114，： | 1 |
| 16 | Coracoclavicular ligament reconstruction using the lateral half of the conjoined tendon 显示文摘 | Sloan SM Budoff JE Hipp JA | 2004 | J Shoulder Elbow Surg2004，13，2： | 1 |
| 17 | Assess- ment of coronary artery disease by cardiac computed tomo- graphy: a scientific statement from the American Heart Asso- ciation Committee on Cardiovascular Imaging and Interven- tion, Council on Cardiovascular Radiology and Intervention, and Committee on Cardiac Imaging, Council on Clinical Car- diology显示文摘 | Budoff M J Achenbach S Blumenthal R S | 2006 | Circulation2006，114，16： | 1 |
| 18 | Accurate measures of left ventricular ejection fraction using electron beam tomography: A comparison with radionuclide angiography, and cine angiography显示文摘 | Howard K. Baik Matthew J. Budoff Kathleen L. Lane Hamid Bakhsheshi Bruce H. Brundage | 2000 | The International Journal of Cardiac Imaging2000，，5： | 1 |
| 19 | Assessment of coronary artery disease by cardiac computed tomography:a scientific statement from the American Heart Association Committee on Cardiac Imaging,Council on Clinical Cardiology显示文摘 | Budoff M J Achembach S Blumenthal R S | 2006 | Circulation2006，114，58： | 1 |
| 20 | Determinants of coronary artery caleification in diabetics with and without nephropathy 显示文摘 | Mehrotra R Budoff M Christenson P | 2004 | Kidney Int2004，66，5： | 1 |
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