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| 1 | Abnormalities of uterine cervix in women with inflammatory bowel disease显示文摘AIM: To evaluate the prevalence of abnormalities of the uterine cervix in women with inflammatory bowel disease (IBD) when compared to healthy controls. METHODS: One hundred and sixteen patients with IBD [64 with Crohn’s disease (CD) and 52 with ulcerative colitis (UC)] were matched to 116 healthy controls by age (+/- 2 years) at the time of most recent papanicolaou (Pap) smear. Data collected consisted of age, race, marital status, number of pregnancies, abortions/miscarriages, duration and severity of IBD, Pap smear results within five years of enrollment, and treatment with immunosuppressive drugs. Pap smear results were categorized as normal or abnormal including atypical squamous cells of undetermined significance (ASCUS), low-grade squamous intraepithelial lesion (LGSIL), and high-grade squamous intraepithelial lesion (HGSIL). RESULTS: The median age at the time of Pap smear was 46 (range: 17-74) years for the IBD group and matched controls (range: 19-72 years). There were more Caucasian subjects than other ethnicities in the IBD patient group (P = 0.025), as well as fewer abortions (P = 0.008), but there was no significant difference regarding marital status. Eighteen percent of IBD patients had abnormal Pap smears compared to 5% of controls (P = 0.004). Subgroup analysis of the IBD patients revealed no significant differences between CD and UC patients in age, ethnicity, marital status, number of abortions, disease severity, family history of IBD, or disease duration. No significant difference was observedin the number of abnormal Pap smears or the use of immunosuppressive medications between CD and UC patients (P = 0.793). No definitive observation could be made regarding HPV status, as this was not routinely investigated during the timeframe of our study. CONCLUSION: Diagnosis of IBD in women is related to an increased risk of abnormal Pap smear, while type of IBD and exposure to immunosuppressive medications are not. This has significant implications for women with IBD in that Pap smear screening protocols should be conscientiously followed, with appropriate investigation of abnormal results. | Jyoti Bhatia Jason Bratcher Burton Korelitz Katherine Vakher Shlomo Mannor Maria Shevchuk Gworgia Panagopoulos Adam Ofer Ecaterina Tamas Panayota Kotsali Oana Vele | 2006 | World Journal of Gastroenterology2006,12,38: | 3 |
| 2 | Cephalosporins: A Review显示文摘 | Harrison C J Bratcher D | 2008 | Pediatr Rev2008,29,8: | 1 |
| 3 | Mechanisms of endothelial dysfunction with development of type 1 diabetes mellitus role of insulin and C-peptide显示文摘 | Bratcher A P Rodriguez W E Tyagi S C | 2005 | Cell Biochem2005,96,6: | 1 |
| 4 | Instrumented open-door laminoplasty as treatment for cervical myelopathy in 104 patients显示文摘 | Dimar JR 2nd Bratcher KR Brock DC | | 0,,07: | 1 |
| 5 | Noncovalent and nonspecific molecular interactions of polymers with mul- tiwalled carbon nanotubes 显示文摘 | Baskaran D Mays J W Bratcher M S | 2005 | Chemistry of Materials2005,17,13: | 1 |
| 6 | Instrumented open-door laminoplasty as treatment for cervical myelop- athy in 104 patients 显示文摘 | Dimar JR Bratcher KR Brock DC | 2009 | Am J Ortho2009,38,7: | 1 |
| 7 | Two-dimensional re-image assisted phased array architecture for coherent beam combination显示文摘 | Bratcher A Uberna R | 2009 | Journal of Directed Energy2009,3,: | 1 |
| 8 | Nosocomial infection rates in US children' s hospitals' neonatal and pediatric intensive care units显示文摘 | Stover BH Shulman ST Bratcher DF | 2001 | Am J Infect Control2001,29,3: | 1 |
| 9 | Coherent polarization beam combination显示文摘 | Uberna Radoslaw Bratcher Andrew Tiemann Bruce G | 2010 | Journal of Quantum Electronics2010,46,8: | 1 |
| 10 | Parameter subset selection and multiple comparisons of Poisson rate parameters with misclassification显示文摘 | STAMEY J D BRATCHER T L YOUNG D M | 2004 | Computational Statistics and Data Analysis2004,45,3: | 1 |
| 11 | Effect of passive antibody on congenital cytomegalovirus infection in guinea pigs显示文摘 | Bratcher DF Bourne N Bravo FJ | | 0,,: | 1 |
| 12 | Choledochoscopy-assisted in-traductal shock wave lithotripsy显示文摘 | Bratcher J Kasmin F | 2009 | Gastrointest Endosc Clin N Am2009,19,4: | 1 |
| 13 | A gene-by-gene population genomics platform: denovo assembly, annotation and genealogical analysis of 108 representative Neisseria meningitidis genomes显示文摘 | Bratcher HB Corton C Jolley KA | 2014 | BMC Genomics2014,15,1: | 1 |
| 14 | Behavioral profile of P2X(7) receptor knockout mice in animal models of depression and anxiety:Relevance for neuropsychiatric disorders显示文摘 | Basso AM Bratcher NA Harris RR | 2008 | Behav Brain Res2008,10,18: | 1 |
| 15 | Instru-mented open-door laminoplasty as treatment for cervical myelopathy in 104 patients 显示文摘 | Dimar JR 2nd Bratcher KR Brock DC | 2009 | Am J Orthop2009,38,7: | 1 |
| 16 | Predictive Factors for the Use of Autologous Cell Saver Transfusion in Lumbar Spinal Surgery显示文摘 | Roger Kirk Owens Charles H. Crawford Mladen Djurasovic Chelsea E. Canan Lauren O. Burke Kelly R. Bratcher Kathryn J. McCarthy Leah Yacat Carreon | 2013 | Spine2013,,4: | 1 |
| 17 | Identification of natural pneumococcal isolates expressing serotype 6D by genetic,biochemical,and serological characterization显示文摘 | Bratcher PE Kim KH Kang JH | 2010 | Microbiology2010,156,2: | 1 |
| 18 | Identification of natural pneumococcal isolates expressing serotype 6D by genetic,biochemical and serological characterization显示文摘 | Bratcher PE Kim KH Kang JH | 2010 | Microbiology2010,156,2: | 1 |
| 19 | Blood Salvage Produces Higher Total Blood Product Costs in Single-Level Lumbar Spinal Surgery显示文摘 | Chelsea E. Canan Roger K. Owens Charles H. Crawford Mladen Djurasovic Lauren O. Burke Kelly R. Bratcher Kathryn J. McCarthy John A. Myers Leah Y. Carreon | 2012 | The Spine Journal2012,,9: | 1 |
| 20 | Evolution of the capsular gene locus of Streptococcus pneumonia serogroup 6显示文摘 | Bratcher PE Park IH Oliver MB | 2011 | Microbiology2011,157,1: | 1 |