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47篇 您的检索式:作者名="Block L G"
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1Targeted therapy in advanced metastatic colorectal cancer: Current concepts and perspectives显示文摘The introduction of new cytotoxic substances as well as agents that target vascular endothelial growth factor(VEGF)and epidermal growth factor receptor(EGFR)signaling has improved clinical outcome of patients withmetastatic colorectal cancer(mCRC).In this review we summarize the most relevant clinical data on VEGF and EGFR targeting regimens in mCRC.The effects of available treatment strategies for mCRC are often temporary,with resistance and disease progression developing in most patients.Thus,new treatment strategies are urgently needed.Some GI peptides including gastrin and gastrin releasing peptide,certain growth factors such as insulin-like growth factor-ⅠandⅡand neuropeptides such as growth hormone releasing hormone(GHRH)are implicated in the growth of CRC.Experimental investigations in CRC with antagonistic analogs of bombesin/gastrin-releasing peptide,GHRH,and with cytotoxic peptides that can be targeted to peptide receptors on tumors,are summarized in the second part of the review.Florian Hohla Thomas Winder Richard Greil Ferenc G Rick Norman L Block rew V Schally 2014World Journal of Gastroenterology2014,20,20:3
2Mortality after emergent percutaneous coro- nary intervention in cardiogenic shock secondary to acute myo- cardial infarction and usefulness of a mortality prediction model 显示文摘Klein L W Shaw R E Krone R J Brindis R G Anderson H V Block P C 2005Am J Cardiol2005,96,:1
3The major genetic determinants of HIV-1control affect HLA class I peptide presentation显示文摘International HIV Controllers Study Pereyra F Jia X McLaren P J Telenti A de Bakker P I Walker B D Ripke S Brumme C J Pulit S L Carrington M Kadie C M Carlson J M Heckerman D Graham R R Plenge R M Deeks S G Gianniny L Crawford G Sullivan J Gonzalez E Davies L Camargo A Moore JM Beattie N Gupta S Crenshaw A Burtt N P Guiducci C Gupta N Gao X Qi Y Yuki Y Piechocka-Trocha A Cutrell E Rosenberg R Moss K L Lemay P O'Leary J Schaefer T Verma P Toth I Block B Baker B Rothchild A Lian J Proudfoot J Alvino D M Vine S Addo M M Allen T M Altfeld M Henn M R Le Gall S Streeck H Haas D W Kuritzkes D R Robbins G K Shafer R W Gulick R M Shikuma C M Haubrich R Riddler S Sax P E Daar E S Ribaudo H J Agan B Agarwal S Ahern R L Allen B L Altidor S Altschuler E L Ambardar S Anastos K Anderson B Anderson V Andrady U Antoniskis D Bangsberg D Barbaro D Barrie W Bartczak J Barton S Basden P Basgoz N Bazner S Bellos N C Benson A M Berger J Bernard N F Bernard A M Birch C Bodner S J Bolan R K Boudreaux E T Bradley M Braun J F Brndjar J E Brown S J Brown K Brown S T Burack J Bush LM Cafaro V Campbell O Campbell J Carlson R H Carmichael J K Casey K K Cavacuiti C Celestin G Chambers S T Chez N Chirch L M Cimoch P J Cohen D Cohn LE Conway B Cooper D A Cornelson B Cox D T Cristofano M V Cuchural G Jr Czartoski J L Dahman J M Daly J S Davis B T Davis K Davod S M DeJesus E Dietz C A Dunham E Dunn M E Ellerin T B Eron J J Fangman J J Farel C E Ferlazzo H Fidler S Fleenor-Ford A Frankel R Freedberg K A French N K Fuchs JD Fuller J D Gaberman J Gallant J E Gandhi R T Garcia E Garmon D Gathe J C Jr Gaultier C R Gebre W Gilman F D Gilson I Goepfert P A Gottlieb M S Goulston C Groger R K Gurley T D Haber S Hardwicke R Hardy W D Harrigan P R Hawkins T N Heath S Hecht F M Henry W K Hladek M Hoffman R P Horton J M Hsu R K Huhn G D Hunt P Hupert M J Illeman M L Jaeger H Jellinger R M John M Johnson J A Johnson K L Johnson H Johnson K Joly J Jordan W C Kauffman C A Khanlou H Killian R K Kim A Y Kim D D Kinder C A Kirchner J T Kogelman L Kojic E M Korthuis P T Kurisu W Kwon D S LaMar M Lampiris H Lanzafame M Lederman M M Lee D M Lee J M Lee M J Lee E T Lemoine J Levy J A Llibre J M Liguori M A Little S J Liu A Y Lopez A J Loutfy M R Loy D Mohammed D Y Man A Mansour M K Marconi V C Markowitz M Marques R Martin J N Martin H L Jr Mayer K H McElrath M J McGhee T A McGovern B H McGowan K McIntyre D Mcleod GX Menezes P Mesa G Metroka CE Meyer-Olson D Miller A O Montgomery K Mounzer K C Nagami E H Nagin I Nahass R G Nelson M O Nielsen C Norene D L O'Connor D H Ojikutu B O Okulicz J Oladehin O O Oldfield E C Olender S A Ostrowski M Owen WF Jr Pae E Parsonnet J Pavlatos A M Perlmutter A M Pierce M N Pincus J M Pisani L Price L J Proia L Prokesch R C Pujet H C Ramgopal M Rathod A Rausch M Ravishankar J Rhame F S Richards C S Richman D D Rodes B Rodriguez M Rose R C 3rd Rosenberg E S Rosenthal D Ross P E Rubin D S Rumbaugh E Saenz L Salvaggio M R Sanchez WC Sanjana V M Santiago S Schmidt W Schuitemaker H Sestak P M Shalit P Shay W Shirvani V N Silebi V I Sizemore J M Jr Skolnik P R Sokol-Anderson M Sosman J M Stabile P Stapleton J T Starrett S Stein F Stellbrink H J Sterman FL Stone V E Stone D R Tambussi G Taplitz R A Tedaldi E M Telenti A Theisen W Torres R Tosiello L Tremblay C Tribble M A Trinh P D Tsao A Ueda P Vaccaro A Valadas E Vanig T J Vecino I Vega V M Veikley W Wade B H Walworth C Wanidworanun C Ward D J Warner D A Weber R D Webster D Weis S Wheeler D A White D J Wilkins E Winston A Wlodaver C G van't Wout A Wright D P Yang O O Yurdin D L Zabukovic B W Zachary K C Zeeman B Zhao M 2010Science2010,330,6010:1
4Effect of cold acclimation of the antioxidant defense system of two larval Lepidoptera (Noctuidae)显示文摘GRUBOR L G BLOCK W TELESMANIC M 1997Archives of Insect Biochemistry and Physiology1997,36,1:1
5Congenital mesohlas- tic nephroma(leiomyomatous hamartoma): first adult ease显示文摘Block N L Grabstald H G Melamed M R 1973J Urol1973,110,4:1
6Obstetric and Psychological Effects of Psychoprophylactic Preparation for Childbirth显示文摘Charles A G Norr K L Block C R 1978American Journal of Obstetric and Gynecology1978,131,1:1
7Population extinction and quasi-stationary behavior in stochastic density-dependent structured models 显示文摘Block G L Allen L J S 2000Bull Math Bio2000,62,:1
8Antiooddant vitamins and disease prevetion显示文摘Block G Langseth L 1994Food Technology1994,,7:1
9Beyond protection motivation: An integrative theory of health appeals 显示文摘Block L G Keller P A 1998J Applied Social Psychology1998,28,17:1
10Window displays and consumer shopping decisions显示文摘Sen S Block L G Chandran S 2002Journal of Retailing and Consumer services2002,9,5:1
11Antioxidant vitamins and disease prevention显示文摘BLOCK G LANGSETH L 1994Food Technology1994,48,:1
12Direct detection of Listeria monocytogenes in 25 milliliters of raw milk by a two-step PCR with nested primers显示文摘HERMAN L M F de BLOCK J H G E MOERMANS R J B 1995Applied and Environmental Microbiology1995,61,:1
13Systemic LPS causes chronic neuroinflammation and progres- sive neurodegeneration显示文摘Qin L Wu X Block M L Liu Y Breese G R Hong J S 2007Glia2007,55,:1
14Congenital mesoblastie nephroma (leiomyomatous hamartoma) : first adult case 显示文摘Block N L Grabstald H G Melamed M R 1973J Urol1973,110,4:1
15Insulin-like growth hormone (GH) levels in canine cerebro- spinal fluid are unaffected by GH or GH secretagogue ( MK - 0677 ) administration 显示文摘Prahalada S Block G Handt L 1999Horm Metab Res1999,31,23:1
16Cloning and sequence analysis of the extracellular region of the polar bear (Ursus maritimus)luteinizing hormone receptor (LHr), follicle stimulating hormone receptor (FSHr),and prolactin receptor (PRLr)genes and their expression in the testis of black bear (Ursus americanus) 显示文摘Howell-Skalla L Bunick D Block G 2000Mol Reprod Dev2000,55,2:1
17Nanometer size diesel exhaust particles are selectively toxic to dopaminergic neurons: the role of microglia, phagocytosis, and NADPH oxidase显示文摘Block M L Wu X Pei Z Li G Wang T Qin L 2004FASEB J2004,18,:1
18Direct detection of listeriamonocytogenes in 25 milliliters of raw milk by a two-step PCR with nested primers显示文摘HERMAN L M F BLOCK J H G E MOERMANS R J B 1995Applied and Environmental Microbiology1995,,61:1
19Antioxidant enzymes in larv a of the Antarctic fly, Belgica antarctica显示文摘Grubor L G Block W Jovanovic A 1996Cryo Letters1996,17,1:1
20Effect of cold acclimation of the antioxidant defense system of two larval Lepidoptera (Noctuidae)显示文摘Grubor L G Block W Telesmanic M 1997Archives of Insect Biochemistry and Physiology1997,36,1:1
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