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| 1 | Surgical outcome after docetaxel-based neoadjuvant chemotherapy in locally-advanced gastric cancer显示文摘AIM:To investigate feasibility,morbidity and surgical mortality of a docetaxel-based chemotherapy regimen randomly administered before or after gastrectomy in patients suffering from locally-advanced resectable gastric cancer.METHODS:Patients suffering from locally-advanced(T3-4 any N M0 or any T N1-3 M0)gastric carcinoma,staged with endoscopic ultrasound,bone scan,computed tomography,and laparoscopy,were assigned to receive four 21 d/cycles of TCF(docetaxel 75 mg/m 2 day 1,cisplatin 75 mg/m 2 day 1,and fluorouracil 300 mg/m 2 per day for days 1-14),either before(Arm A)or after(Arm B)gastrectomy.Operative morbidity,overall mortality,and severe adverse events were compared by intention-to-treat analysis.RESULTS:From November 1999 to November 2005,70 patients were treated.After preoperative TCF(Arm A),thirty-two(94%)resections were performed,85% of which were R0.Pathological response was complete in 4 patients(11.7%),and partial in 18(55%).No surgical mortality and 28.5%morbidity rate were observed,similar to those of immediate surgery arm(P= 0.86).Serious chemotherapy adverse events tended to be more frequent in arm B(23%vs 11%,P=0.07),with a single death per arm.CONCLUSION:Surgery following docetaxel-based chemotherapy was safe and with similar morbidity to immediate surgery in patients with locally-advanced resectable gastric carcinoma. | Roberto Biffi Nicola Fazio Fabrizio Luca Antonio Chiappa Bruno Andreoni Maria Giulia Zampino Arnaud Roth Jan Christian Schuller Giancarla Fiori Franco Orsi Guido Bonomo Cristiano Crosta Olivier Huber | 2010 | World Journal of Gastroenterology2010，16，7： | 43 |
| 2 | Dealing with robot-assisted surgery for rectal cancer:current status and perspectives显示文摘The laparoscopic approach for treatment of rectal cancer has been proven feasible and oncologically safe, and is able to offer better short-term outcomes than traditional open procedures, mainly in terms of reduced length of hospital stay and time to return to working activity. In spite of this, the laparoscopic technique is usually practised only in high-volume experienced centres, mainly because it requires a prolonged and demanding learning curve. It has been estimated that over 50 operations are required for an experienced colorectal surgeon to achieve proficiency with this technique. Robotic surgery enables the surgeon to perform minimally invasive operations with better vision and more intuitive and precise control of the operating instruments, thus promising to overcome some of the technical difficulties associated with standard laparoscopy. It has high-definition threedimensional vision, it translates the surgeon's hand movements into precise movements of the instruments inside the patient, the camera is held and moved by the first surgeon, and a fourth robotic arm is available as a fixed retractor. The aim of this review is to summarise the current data on clinical and oncologic outcomes of robot-assisted surgery in rectal cancer, focusing on short- and long-term results, and providing original data from the authors' centre. | Roberto Biffi Fabrizio Luca Paolo Pietro Bianchi Sabina Cenciarelli Wanda Petz Igor Monsellato Manuela Valvo Maria Laura Cossu Tiago Leal Ghezzi Kassem Shmaissany | 2016 | World Journal of Gastroenterology2016，22，2： | 3 |
| 3 | ERCC1 predicts outcome in patients with gastric cancer treated with adjuvant cisplatin-based chemotherapy显示文摘 | Sara Dosso Elena Zanellato Martina Nucifora Renzo Boldorini Angelica Sonzogni Roberto Biffi Nicola Fazio Eraldo Bucci Ottavio Beretta Stefano Crippa Piercarlo Saletti Milo Frattini | 2013 | Cancer Chemotherapy and Pharmacology2013，，1： | 2 |
| 4 | Impact of Robotic Surgery on Sexual and Urinary Functions After Fully Robotic Nerve-Sparing Total Mesorectal Excision for Rectal Cancer显示文摘 | Fabrizio Luca Manuela Valvo Tiago Leal Ghezzi Massimiliano Zuccaro Sabina Cenciarelli Cristina Trovato Angelica Sonzogni Roberto Biffi | 2013 | Annals of Surgery2013，，4： | 2 |
| 5 | The nutritional risk in oncology: a study of 1,453 cancer outpatients显示文摘 | Federico Bozzetti Luigi Mariani Salvatore Lo Vullo Maria Amerio Roberto Biffi Riccardo Caccialanza Giovanni Capuano Isabel Correja Luca Cozzaglio Angelo Di Leo Leonardo Di Cosmo Concetta Finocchiaro Cecilia Gavazzi Antonello Giannoni Patrizia Magnanini Gi | 2012 | Supportive Care in Cancer2012，，8： | 2 |
| 6 | Comparison between cationic Polymers and lipids in mediating systemic gene delivery to the lung 显示文摘 | Bragonzi A Boletta A Biffi A | 1999 | Gene Ther1999，6，12： | 1 |
| 7 | Long term clinical significance of frequent and complex ventricular tachyarrhythmias in trained athletes显示文摘 | Biffi A Pelliccia A Verdile L | 2002 | J Am Coll Cardiol2002，40，3： | 1 |
| 8 | Oral loading with propafenone for conversion of recent-onset atrial fibrillation:a review on in-hospital treatment显示文摘 | BORIANI G MARTIGNANI C BIFFI M | 2002 | Drugs2002，62，3： | 1 |
| 9 | Evaluation of myocardial injury following injury repeated internal atrial shocks by monitoring serum cardiac troponin I levels显示文摘 | BorianiG Biffi M Cervi V | | 0，，： | 1 |
| 10 | Passive damping of slender and light structures 显示文摘 | Bassani P Biffi C A Carnevale M | 2013 | Materials & Design2013，45，： | 1 |
| 11 | 12-lead ECG in the athlete: physiological versus pathological abnormalities显示文摘 | Corrado D Biffi A Basso C | 2009 | Br J Sports Med2009，43，9： | 1 |
| 12 | Catalysis by metal nanoparticles supported on functional organic polymers显示文摘 | Kralik M Biffis A | 2001 | Journal of Molecular Catalysis A: Chemical2001，177，： | 1 |
| 13 | Mesozoic northeast Qaidam basin: response to contractional reactivation of the Qilian Shan, and implications for the extent of Mesozoic intracontinental deformation in central Asia 显示文摘 | Ritts B D Biffi U | 2001 | Geological Society of America2001，194，： | 1 |
| 14 | Selective expression of interleukin-12 receptor component by human helper T cells显示文摘 | ROCHE L MAINO LB BIFFI M | 1997 | J Exp Med1997，185，5： | 1 |
| 15 | VDR-dependent regulation of mast cell maturation mediated by 1,25-dihydroxyvitamin D3显示文摘 | BARONIE BIFFI M BENIGNI F | 2007 | Leukoc Biol2007，81，1： | 1 |
| 16 | Aspirin and recurrentintracerebral hemorrhage in cerebral amyloid angiopathy显示文摘 | Biffi A Halpin A Towfighi A | 2010 | Neurology2010，75，8： | 1 |
| 17 | Functionalised microgels: novel stabilisers for catalytically active metal colloids 显示文摘 | BIFFIS A | 2001 | Journal of Molecular Catalysis A: Chemical2001，165，12： | 1 |
| 18 | International evidence-based recommendations on ultrasound-guided vascular access显示文摘 | Massimo Lamperti Andrew R. Bodenham Mauro Pittiruti Michael Blaivas John G. Augoustides Mahmoud Elbarbary Thierry Pirotte Dimitrios Karakitsos Jack LeDonne Stephanie Doniger Giancarlo Scoppettuolo David Feller-Kopman Wolfram Schummer Roberto Biffi Eric De | 2012 | Intensive Care Medicine2012，，7： | 1 |
| 19 | 显示文摘 | Biffis A Zecca M Basato M | 2001 | J Mol Cata A: Chem2001，173，： | 1 |
| 20 | Impact on survival of the number of lymph nodes removed in patients with nodenegative gastric cancer submitted to extended lymph node dissection显示文摘 | Biffi R Botteri E Cenciarelli S | 2011 | Eur J Surg Oncol2011，37，4： | 1 |
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