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| 1 | Computed tomography-guided percutaneous core needle biopsy in pancreatic tumor diagnosis显示文摘AIM: To evaluate the techniques, results, and complications related to computed tomography(CT)-guided percutaneous core needle biopsies of solid pancreatic lesions.METHODS: CT-guided percutaneous biopsies of solid pancreatic lesions performed at a cancer reference center between January 2012 and September 2013 were retrospectively analyzed. Biopsy material was collected with a 16-20 G Tru-Core needle(10-15 cm; Angiotech, Vancouver, CA) using a coaxial system and automatic biopsy gun. When direct access to the lesion was not possible, indirect(transgastric or transhepatic) access or hydrodissection and/or pneumodissection maneuvers were used. Characteristics of the patients, lesions, procedures, and histologic results were recorded using a standardized form. RESULTS: A total of 103 procedures included in the study were performed on patients with a mean age of 64.8 year(range: 39-94 year). The mean size of the pancreatic lesions was 45.5 mm(range: 15-195 mm). Most(75/103, 72.8%) procedures were performed via direct access, though hydrodissection and/or pneumodissection were used in 22.2%(23/103) of cases and indirect transhepatic or transgastric access was used in 4.8%(5/103) of cases. Histologic analysis was performed on all biopsies, and diagnoses were conclusive in 98.1%(101/103) of cases, confirming3.9%(4/103) of tumors were benign and 94.2%(97/103) were malignant; results were atypical in 1.9%(2/103) of cases, requiring a repeat biopsy to diagnose a neuroendocrine tumor, and surgical resection to confirm a primary adenocarcinoma. Only mild/moderate complications were observed in 9/103 patients(8.7%),and they were more commonly associated with biopsies of lesions located in the head/uncinate process(n =8), than of those located in the body/tail(n = 1) of the pancreas, but this difference was not significant.CONCLUSION: CT-guided biopsy of a pancreatic lesion is a safe procedure with a high success rate, and is an excellent option for minimally invasive diagnosis. | Chiang J Tyng Maria Fernanda A Almeida Paula NV Barbosa Almir GV Bitencourt José Augusto AG Berg Macello S Maciel Felipe JF Coimbra Luiz Henrique O Schiavon Maria Dirlei Begnami Marcos D Guimares Charles E Zurstrassen Rubens Chojniak | 2015 | World Journal of Gastroenterology2015，21，12： | 14 |
| 2 | Autophagosome-associated variant isoforms of cytosolic enzymes显示文摘 | Fengsrud M Raiborg C Berg TO Strmhaug PE Ueno T Erichsen ES Seglen PO | 2000 | Biochem J2000，352，3： | 1 |
| 3 | Sequence analysis of HIV-1 group O from Norwegian patients infected in the 1960s 显示文摘 | Jonassen TO Stene-Johansen K Berg ES | 1997 | Virology1997，231，： | 1 |
| 4 | An assessment of bioreactor landfill costs and benefits显示文摘 | Berge ND Reinhart DR Batarseh ES | 2009 | Waste Management2009，29，5： | 1 |
| 5 | Molicular mak- er for diagnostic cytology of neoplasms in the head region of pan- creases: mutation of K - ras and over expression of I:'53 protion product显示文摘 | Van Es JM Polak MM Van Den Berg FM et 81 | 1995 | J Clin Pathol1995，48，3： | 1 |
| 6 | Ultrastructural character-ization of the delimiting membranes of isolated autophagosomes andamphisomes by freeze-fracture electron microscopy 显示文摘 | Fengsrud M Erichsen ES Berg TO | 2000 | Eur J Cell Bi-ol2000，79，12： | 1 |
| 7 | Targeting development of incretin-producing cells increases insulin secretion显示文摘 | Petersen N Reimann F van Es JH van den Berg BM Kroone C Pais R | 2015 | J Clin Invest2015，125，1： | 1 |
| 8 | Motilin receptor expression in smooth muscle,myenteric plexus,and mucosa of human inflamed and noninflamed intestine显示文摘 | Ter Beck WP Muller ES van den Berg M | 2008 | Inflamm Bowel Dis2008，14，5： | 1 |
| 9 | False-negative results of a ligase chain reaction assay to detect Chlamydia trachomatis due to inhibitors in urine 显示文摘 | Berg ES Anestad G Moi H | 1997 | Eur J Clin Microbiol Infect Dis1997，16，： | 1 |
| 10 | Sequence analysis of HIV-1 group O from Norwegian patients infected in the 1960s显示文摘 | Jonassen TO Stene-Johansen K Berg ES | 1997 | Virology1997，231，1： | 1 |
| 11 | Regulation of the function of the first component of complement by human C1q receptor显示文摘 | Faber-Krol M van Es LA | 1995 | Eur J Immunol1995，25，： | 1 |
| 12 | Tau levels do not influence human ALS or motor neuron degeneration in the SOD1G93A mouse显示文摘 | I. Taes A. Goris R. Lemmens M.A. van Es L.H. van den Berg A. Chio B.J. Traynor A. Birve P. Andersen A. Slowik B. Tomik R.H. Brown C.E. Shaw A. Al-Chalabi S. Boonen L. Van Den Bosch B. Dubois P. Van Damme W. Robberecht | 2010 | Neurology2010，，21： | 1 |
| 13 | Motilin receptor expression in smooth muscle,myenteric plexus,and mucosa of human inflamed and noninflamed intestine显示文摘 | Ter Beek WP Muller ES van den Berg M | | 0，，05： | 1 |
| 14 | Regulation of the function of the first component of complement by human C1q receptor 显示文摘 | Faber Krol M van Es LA | 1995 | Eur J Immunol1995，25，8： | 1 |
| 15 | Definition of early childhood caries显示文摘 | Barr ES Berg JH Bookwalter CA | 2005 | Pediatr Dent2005，27，7： | 1 |
| 16 | Malignant stromal tumour of the rectum:findings at endorectal ultrasound and MRI显示文摘 | van den Berg JC van Heesewijk JP van Es HW | 2000 | Br J Radiol2000，73，873： | 1 |
| 17 | False-negative results of a LCR assay to detect CT due to inhibitors in urine显示文摘 | Anestad G Moi H | 1997 | Eur J Clin Microbiol Infect Dis1997，16，10： | 1 |
| 18 | Magnetic resonance imaging of the brachial plexus in patients with multifocal motor neuropathy显示文摘 | Van den Berg LH Franssen H | 1997 | Neurology1997，48，5： | 1 |
| 19 | Glycocalyx and endothelial (dys) function:from mice to men显示文摘 | Van den Berg BM Nieuwdorp M Stroes ES | 2006 | Pharmacol Rep2006，58，： | 1 |
| 20 | Ultrastructural characterization of the delimiting membranes of isolated autophagosomes and amphisomes by freeze-fracture electron microscopy显示文摘 | Fengsrud M Erichsen ES Berg TO | 2000 | Eur J Cell Biol2000，79，12： | 1 |
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