|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Blood loss,predictors of bleeding,transfusion practice and strategies of blood cell salvaging during liver transplantation显示文摘Blood loss during liver transplantation (OLTx) is a common consequence of pre-existing abnormalities of the hemostatic system,portal hypertension with multiple collateral vessels,portal vein thrombosis,previous abdominal surgery,splenomegaly,and poor 'functional' recovery of the new liver.The intrinsic coagulopathic features of end stage cirrhosis along with surgical technical difficulties make transfusion-free liver transplantation a major challenge,and,despite the improvements in understanding of intraoperative coagulation profiles and strategies to control blood loss,the requirements for blood or blood products remains high.The impact of blood transfusion has been shown to be significant and independent of other well-known predictors of posttransplant-outcome.Negative effects on immunomodulation and an increased risk of postoperative complications and mortality have been repeatedly demonstrated.Isovolemic hemodilution,the extensive utilization of thromboelastogram and the use of autotransfusion devices are among the commonly adopted procedures to limit the amount of blood transfusion.The use of intraoperative blood salvage and autologous blood transfusion should still be considered an important method to reduce the need for allogenic blood and the associated complications.In this article we report on the common preoperative and intraoperative factors contributing to blood loss,intraoperative transfusion practices,anesthesiologic and surgical strategies to prevent blood loss,and on intraoperative blood salvaging techniques and autologous blood transfusion.Even though the advances in surgical technique and anesthetic management,as well as a better understanding of the risk factors,have resulted in a steady decrease in intraoperative bleeding,most patients still bleed extensively.Blood transfusion therapy is still a critical feature during OLTx and various studies have shown a large variability in the use of blood products among different centers and even among individual anesthesiologists within the same center.Unfortunately,despite the large number of OLTx performed each year,there is still paucity of large randomized,multicentre,and controlled studies which indicate how to prevent bleeding,the transfusion needs and thresholds,and the 'evidence based' perioperative strategies to reduce the amount of transfusion. | Feltracco Paolo Brezzi Marialuisa Barbieri Stefania Galligioni Helmut Milevoj Moira Carollo Cristiana Ori Carlo | 2013 | World Journal of Hepatology2013，5，1： | 37 |
| 2 | Early respiratory complications after liver transplantation显示文摘The poor clinical conditions associated with end-stage cirrhosis,pre-existing pulmonary abnormalities,and high comorbidity rates in patients with high Model for End-Stage Liver Disease scores are all well-recognized factors that increase the risk of pulmonary complications after orthotopic liver transplantation(OLT)surgery.Many intraoperative and postoperative events,such as fluid overload,massive transfusion of blood products,hemodynamic instability,unexpected coagulation abnormalities,renal dysfunction,and serious adverse effects of reperfusion syndrome,are other factors that predispose an individual to postoperative respiratory disorders.Despite advances in surgical techniques and anesthesiological management,the lung may still suffer throughout the perioperative period from various types of injury and ventilatory impairment,with different clinical outcomes.Pulmonary complications after OLT can be classified as infectious or non-infectious.Pleural effusion,atelectasis,pulmonary edema,respiratory distress syndrome,and pneumonia may contribute considerably to early morbidity and mortality in liver transplant patients.It is of paramount importance to accurately identify lung disorders because infectious pulmonary complications warrant speedy and aggressive treatment to prevent diffuse lung injury and the risk of evolution into multisystem organ failure.This review discusses the most common perioperative factors that predispose an individual to postoperative pulmonary complications and these complications’early clinical manifestations after OLT and influence on patient outcome. | Paolo Feltracco Cristiana Carollo Stefania Barbieri Tommaso Pettenuzzo Carlo Ori | 2013 | World Journal of Gastroenterology2013，19，48： | 32 |
| 3 | Intensive care management of liver transplanted patients显示文摘Advances in pre-transplant treatment of cirrhosis-related organ dysfunction,intraoperative patient management,and improvements in the treatment of rejection and infections have made human liver transplantation an effective and valuable option for patients with end stage liver disease.However,many important factors,related both to an increasing 'marginality' of the implanted graft and unexpected perioperative complications still make immediate post-operative care challenging and the early outcome unpredictable.In recent years sicker patients with multiple comorbidities and organ dysfunction have been undergoing Liver transplantation;appropriate critical care management is required to support prompt graft recovery and prevent systemic complications.Early post-operative management is highly demanding as significant changes may occur in both the allograft and the 'distant' organs.A functioning transplanted liver is almost always associated with organ system recovery,resulting in a new life for the patient.However,in the unfortunate event of graft dysfunction,the unavoidable development of multi-organ failure will require an enhanced level of critical care support and a prolonged ICU stay.Strict monitoring and sustainment of cardiorespiratory function,frequent assessment of graft performance,timely recognition of unexpected complications and the institution of prophylactic measures to prevent extrahepatic organ system dysfunction are mandatoryin the immediate post-operative period.A reduced rate of complications and satisfactory outcomes have been obtained from multidisciplinary,collaborative efforts,skillful vigilance,and a thorough knowledge of pathophysiologic characteristics of the transplanted liver. | Paolo Feltracco Stefania Barbieri Helmut Galligioni Elisa Michieletto Cristiana Carollo Carlo Ori | 2011 | World Journal of Hepatology2011，3，3： | 13 |
| 4 | Perioperative thrombotic complications in liver transplantation显示文摘Although the perioperative bleeding complications and the major side effects of blood transfusion have always been the primary concern in liver transplantation(OLT),the possible cohesion of an underestimated intrinsic hypercoagulative state during and after the transplant procedure may pose a major threat to both patient and graft survival.Thromboembolism during OLT is characterized not only by a complex aetiology,but also by unpredictable onset and evolution of the disease.The initiation of a procoagulant process may be triggered by various factors,such as inflammation,venous stasis,ischemia-reperfusion injury,vascular clamping,anatomical and technical abnormalities,genetic factors,deficiency of profibrinolytic activity,and platelet activation.The involvement of the arterial system,intracardiac thrombosis,pulmonary emboli,portal vein thrombosis,and deep vein thrombosis,are among the most serious thrombotic events in the perioperative period.The rapid detection of occlusive vascular events is of paramount importance as it heavily influences the prognosis,particularly when these events occur intraoperatively or early after OLT.Regardless of the lack of studies and guidelines on anticoagulant prophylaxis in this setting,many institutions recommend such an approach especially in the subset of patients at high risk.However,the decision of when,how and in what doses to use the various chemical anticoagulants is still a difficult task,since there is no common consensus,even for highrisk cases.The risk of postoperative thromboembolism causing severe hemodynamic events,or even loss of graft function,must be weighed and compared with the risk of an important bleeding.In this article we briefly review the risk factors and the possible predictors of major thrombotic complications occurringin the perioperative period,as well as their incidence and clinical features.Moreover,the indications to pharmacological prophylaxis and the current treatment strategies are also summarized. | Paolo Feltracco Stefania Barbieri Umberto Cillo Giacomo Zanus Marco Senzolo Carlo Ori | 2015 | World Journal of Gastroenterology2015，21，26： | 13 |
| 5 | Advances and development trends in eco-friendly pavements显示文摘The major contemporary in road pavement engineering is related to the creation of green and sustainable infrastructures,e.g.,reduction of environmental impacts,increase in traffic safety,and transportation efficiency,etc.This review presents the recent trends in research and the technical solutions developed so far to address these challenges.After the analysis of research status in the past decades,a novel technology system of eco-friendly pavements is proposed considering two solutions,materials modification and structure improvement.The construction of an eco-friendly pavement can be achieved thanks to several different technologies ensuring permeable,noise-reducing,self-luminous,and exhaust-decomposing properties as well as apporting lower heat absorbing and enhanced anti-/de-icing characteristics.A systematic review of these technologies is presented pivoting on four main aspects:technical principle,material and structural composition,performance evaluation,and engineering application.The current trend in road engineering is combining the pavement infrastructure with various eco-friendly functions,e.g.,water permeability,noise reduction,low heat absorption,exhaust gas decomposition,and anti-/de-icing.Finally,the review lists the drawbacks of the existing technologies,including high cost,single function,etc.,and depicts the future developing direction and architecture of the next generation of eco-friendly pavements in which the road infrastructure should have more environmentally friendly functions than the existing technology. | Aimin Sha Zhuangzhuang Liu Wei Jiang Lin Qi Liqun Hu Wenxiu Jiao Diego Maria Barbieri | 2021 | Journal of Road Engineering2021，1，1： | 9 |
| 6 | Clinical variability and molecular heterogeneity inprostate cancer显示文摘前列腺癌症是临床上异构的疾病,与当其它有好攻击的、致命的疾病时,有能安全地被观察的懒惰疾病的一些人一起。在过去的十年,研究人员们开始解开了一些贡献这些改变临床的显型的 genomic 异质。前列腺癌症的不同分子的子类被识别了,并且这些子类的唯一被利用了预言临床的结果,为前列腺癌症诊断设计新奇 biomarkers,并且开发新奇治疗学。最近的工作也阐明了前列腺癌症的时间、空间的异质,帮助我们理解疾病致病,对治疗的反应,和前进。新 genomic 技术向我们提供了一扇窗户进显著临床并且前列腺癌症的 genomic 异质,和这个新观点将逐渐地影响耐心的照顾。 | Jonathan Shoag Christopher E Barbieri | 2016 | Asian Journal of Andrology2016，18，4： | 4 |
| 7 | Reduction of Oxidative Stress and Inflammation by Blunting Daily Acute Glucose Fluctuations in Patients With Type 2 Diabetes显示文摘 | Maria Rosaria Rizzo Michelangela Barbieri Raffaele Marfella Giuseppe Paolisso | 2012 | Diabetes Care2012，，10： | 3 |
| 8 | Deletion or underexpression of the Y-chromosome genes CDY2 and HSFY is associated with maturation arrest in American men with nonobstructive azoospermia显示文摘成熟拘捕(麻省) 指导致临床的 nonobstructive 精子缺乏的细菌房间开发的失败。尽管人的 Y 染色体的 azoospermic 因素(AZF ) 区域清楚地在一些情况中被含有,因此,远,很,很少对哪个个人, Y 染色体基因为完全的男细菌房间开发是重要的被知道。我们寻求了在可以在在美国人口与麻省联系的 nonobstructive 精子缺乏的致病被含有的 Y 染色体上识别单个基因。有 Y 染色体 microdeletions 的 132 个人的遗传型显型分析被执行。与麻省联系的编码蛋白质的基因被一张遗传型显型地图的视觉分析识别。与麻省联系的基因在 Y 染色体的一个片断以内作为那些基因被选择完全或部分删除了,总是与可恢复的阴囊的精子的麻省和缺席被联系。每个识别基因抄本的表示然后与自发的麻省和妨碍的精子缺乏从病人的分开的队在阴囊的织物与量的 RT-PCR 被测量。为有麻省的协会的十候选人基因在重叠的 Y 染色体的一个 8.4-Mb 片断以内被识别 AZFb 区域。CDY2 和 HSFY 是唯一的识别了在表示的差别在麻省和妨碍的精子缺乏队之间为被观察的基因。有妨碍的精子缺乏的人有 12 褶层 CDY2 抄本的更高相对的表示(1.33 ± 0.40 对 0.11 ± 0.04;P=0.0003 ) 并且 16 褶层 HSFY 抄本的更高的表示(0.78 ± 0.32 对 0.05 ± 0.02;P=0.0005 ) 与有麻省的人相比。CDY2 和 HSFY 也仅仅是在有 Sertoli 房间的病人的 underexpressed 症候群。这些数据显示 CDY2 和 HSFY 位于为精子成熟是重要的,并且是在与麻省从人导出的阴囊的织物的 underexpressed 的 Y 染色体的一个片断以内。这些观察建议在 CDY2 或 HSFY 表示的缺陷能在麻省的致病被含有。 | Peter J Stahl Anna N Mielnik Christopher E Barbieri Peter N Schlegel Darius A Paduch | 2012 | Asian Journal of Andrology2012，14，5： | 3 |
| 9 | Lexical bundles in university spoken and written registers显示文摘 | Douglas Biber Federica Barbieri | 2006 | English for Specific Purposes2006，，3： | 3 |
| 10 | Postinfarctional remodeling:increased dye intensity in the myocardial risk area after angioplasty of infarct-related coronary artery is associated with reduction of ventricular volumes显示文摘 | DESTRO G MARINO P BARBIERI E | 2001 | J Am Coll Cardiol2001，37，2： | 2 |
| 11 | Primary Lung Cancer Presenting with Gastrointestinal Tract Involvement: Clinicopathologic and Immunohistochemical Features in a Series of 18 Consecutive Cases显示文摘 | Giulio Rossi Alessandro Marchioni Elena Romagnani Federica Bertolini Lucia Longo Alberto Cavazza Fausto Barbieri | 2007 | Journal of Thoracic Oncology2007，，2： | 2 |
| 12 | Sensory property relationship to chemical data of Italian-type dry-cured ham显示文摘 | Careri M Mangia A Barbieri G | 1993 | J Food Science1993，58，： | 2 |
| 13 | Role of free fatty acids on cardiac autonomic nervous system innoninsulin-dependent diabetic patients:effects of metabolic control显示文摘 | Manzella D Barbieri M Rizzo M R | 2001 | Clin Endocrinol Metab2001，86，1： | 1 |
| 14 | Non-synaptic mechanisms underlie the after-effects of cathodal transcutaneous direct current stimulation of the human brain显示文摘 | Ardolino G Bossi B Barbieri S | 2005 | J Physiol2005，568，2： | 1 |
| 15 | Hogh performance latex reagent for hydatid serology purified from cyst fluid in one step显示文摘 | Steria S Battistoni J | 1993 | Int J Parasitol1993，23，5： | 1 |
| 16 | Inter leukin 10 modulates neuronal threshold of valnerability to ischaemic damage显示文摘 | BARBIERI I BASUDEV H | 2000 | Eur J Neurosci2000，12，7： | 1 |
| 17 | Development and validation of a sensitive HPLC-ES1-MS/MS method for the direct determination of glucosanline in human plasma显示文摘 | Roda A Sabatini L Barbieri A | 2006 | J Chromatogr B Anglyt Technol Biomed Life Sci2006，844，1： | 1 |
| 18 | Mechanical resistance of peripheral nerve repair with biological glue and with conventional suture at different postoperative times显示文摘 | Nishimura MT Mazzer N Barbieri CH | 2008 | J Reconstr Microsurg2008，24，5： | 1 |
| 19 | Lack of correlation between environmental or biological indicators of benzene exposure at parts per billion levels and micronuclei induction显示文摘 | VIOLANTE F S SANGUINETrI G BARBIERI A | 2003 | Environmental Research2003，91，3： | 1 |
| 20 | Variation of the incidence of uterine leiomyomata among premenopasual women by ache and race显示文摘 | Marshall LM Spiegelman D Barbieri RL | 1998 | Obstet Gynecol1998，90，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员