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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice显示文摘 | Meira Lisiane B Bugni James M Green Stephanie L Lee Chung-Wei Pang Bo Borenshtein Diana Rickman Barry H Rogers Arlin B Moroski-Erkul Catherine A McFaline Jose L Schauer David B Dedon Peter C Fox James G Samson Leona D | 2008 | Journal of Clinical Investigation2008，，7： | 2 |
| 3 | Influence of Eutrophication on the Distribution of Total Mercury and Methylmercury in Hydroelectric Reservoirs显示文摘 | Meng Bo Feng X B Chen C X Qiu G L Sommar J Guo Y N Liang P Wan Q | 2010 | EN2010，，5： | 2 |
| 4 | Effects of osthole on apoptosis and TGF-bl of hypertrophic scar fibroblasts 显示文摘 | Xiaohua H Bo C Hongqi L | 2009 | J Asian Natural Products Res2009，11，7： | 1 |
| 5 | Intracortical multiplesclerosis lesions are not associatecd with increased lymphocyteinfiltration显示文摘 | Bo L Vedeler C A Nyland H | 2003 | Mult Scler2003，9，4： | 1 |
| 6 | Isolation of a strain of Acidithiobacillus caldus and its role in bioleaching of chalcopyrite显示文摘 | ZHOU Q G BO F BO Z H XI L JIAN G FEI L F HUA C X | 2007 | World Journal of Microbiology and Biotechnology2007，23，9： | 1 |
| 7 | Wavelength converter placement under different RWA algorithms in wavelength-routed all-optical networks显示文摘 | Xiaowen C Bo L Chlamtac I | 2003 | IEEE Transactions on Commmunications2003，51，4： | 1 |
| 8 | Laparoscope - assisted diagnosis and treatment of prepyloric web in children report of three cases 显示文摘 | Bing L Wei - Bing C Shou - Qing W Ye - Bo W | 2013 | J Pediatr Surg2013，48，16： | 1 |
| 9 | Fibroblasts potentiate blood vessel formationpartially through secreted factor TIMP-1显示文摘 | Hua L Bo C Brenda L | 2008 | Angiogenesis2008，11，： | 1 |
| 10 | Optimum design and analysis based on independent reaction amount for distillation column with side reactors: production of benzyl chloride 显示文摘 | Ding L H Tang J H Cui M F Bo C M Chen X Qiao X | 2011 | Industrial & Engineering Chemistry Research2011，50，11： | 1 |
| 11 | Thymosin alpha1 based immunomodulatory therapy for sepsis:a systematic review and meta-analysis显示文摘 | Li C Bo L Liu Q | 2015 | Int J Infecti Dis2015，33，： | 1 |
| 12 | Blood-retinal barrier 显示文摘 | Cunha-Vaz J Bernardes R l~bo C | 2011 | Eur J Ophthalmol2011，21，6： | 1 |
| 13 | Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups显示文摘 | Scherag A Dina C Hinney A Vatin V Scherag S Vogel C I Muller T D Grallert H Wichmann H E Balkau B Heude B Jarvelin M R Hartikainen A L Levy-Marchal C Weill J Delplanque J Korner A Kiess W Kovacs P Rayner N W Prokopenko I McCarthy M I Schafer H Jarick I Bo | | 0，，04： | 1 |
| 14 | Fast sparse approximation for least squares support vector machine显示文摘 | Jiao L C Bo L F Wang L | 2007 | IEEE Trans on Neural Networks2007，18，3： | 1 |
| 15 | Fast sparse approximation for least squares support vector machine 显示文摘 | Jiao L C Bo L F Wang L | 2007 | IEEE Transactions on Neural Networks2007，15，3： | 1 |
| 16 | Physical activity levels and patterns of 9- and 15-yr-old Europe- an children 显示文摘 | RIDDOCH C J BO ANDERSEN L WEDDERKOPP N et a l | 2004 | Med Sci Sport Exe2004，36，1： | 1 |
| 17 | , fed on different dietary protein levels and at different ration levels显示文摘 | Chakraborty S C Ross L G Ross Bo Energy budget and metabolism in common carp cyprinus carpio L | 1995 | Aquaculture Nutrition1995，3，1： | 1 |
| 18 | Survivin as a therapeutic target for radiation sensitization in lung cancer显示文摘 | Bo L Yi M Carolyn C | 2004 | Cancer Res2004，64，15： | 1 |
| 19 | Pelvic floor muscle training for urinary incontinence in women显示文摘 | Hay-Smith E J Bo Berghmans L C Hendriks H J | 2001 | Cochrane Database Syst Rev2001，20，00： | 1 |
| 20 | Greater loss of axons in primary progressive multiple sclerosis plaques compared to secondary progressive disease显示文摘 | Tallantyre E C BO L A1-Rawashdeh O | 2009 | Brain2009，132，5： | 1 |
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