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您的检索式：作者名="Azadeh Aarabi"
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| 1 | Stool-based DNA testing,a new noninvasive method for colorectal cancer screening,the first report from Iran显示文摘AIM:To detect tumor-associated DNA changes in stool samples among Iranian patients with colorectal cancer(CRC)compared to healthy individuals using BAT-26,p16 hypermethylation and long DNA markers.METHODS:Stool DNA was isolated from 45 subjects including 25 CRC patients and 20 healthy individuals using a new,fast and easy extraction method.Long DNA associated with tumor was detected using polymerase chain reaction method.Microsatellite studies were performed utilizing denaturating polyacrylamide gel to determine the instability of BAT-26.Methylation status of p16 promoter was analyzed using methylation-specific PCR(MSP).RESULTS:The results showed a significant difference in existence of long DNA(16 in patients vs 1 in controls,P < 0.001)and p16(5 in patients vs none in controls,P = 0.043)in the stool samples of two groups.Long DNA was detected in 64% of CRC patients;whereas just one of the healthy individuals was positive for Long DNA.p16 methylation was found in 20% of patients and in none of healthy individuals.Instability of BAT-26 was not detected in any of stool samples.CONCLUSION:We could detect colorectal cancer related genetic alterations by analyzing stool DNA witha sensitivity of 64% and 20% and a specificity of 95% and 100% for Long DNA and p16 respectively.A non-invasive molecular stool-based DNA testing can provide a screening strategy in high-risk individuals.However,additional testing on more samples is necessary from Iranian subjects to determine the exact specificity and sensitivity of these markers. | Mohammad Reza Abbaszadegan Alireza Tavasoli Arash Velayati Hamid Reza Sima Hassan Vosooghinia Mehdi Farzadnia Hamid Asadzedeh Mehran Gholamin Ezzat Dadkhah Azadeh Aarabi | 2007 | World Journal of Gastroenterology2007，13，10： | 14 |
| 2 | Cattle toxoplasmosis in Iran:a systematic review and meta-analysis显示文摘Objective:To analyze and review the overall seroprevalence rate of Toxoplasma gondii(T.gondii) infection in cattle from Iran.Methods:In the current study,data collection(published and unpublished papers,abstracts of national scientific congresses and dissertations) using particular terms was carried out systematically on the following electronic databases like PubMed,Google Scholar,Ebsco,Science Direct,Scopus,Magiran,Irandoc,IranMedex and SID(Scientific Information Database).Results:A total of 22 studies since 1983 to 2012 reporting the seroprevalence of toxoplasmosis in cattle from different regions of Iran met our eligibility criteria.The pooled proportion of toxoplasmosis,using random effect model,among cattle in Iran from over the 30-year period was estimated 18.1%(95%CI:9.9%to 28.2%).Conclusions:This study firstly establishes a crude seroprevalence rate of Toxoplasma infection in cattle which can lead us to understand the condition of eattle toxoplasmosis,which have to take into accounted fur an appropriate and effective prevention and controls.Secondly,it compares and discusses elaborately the role of risk factors including sex,age and breed in the epidemiology of the disease.Thus,it determines gaps and drawbacks in the prior studies which are greatly useful to design more accurate investigations in the future. | Shahabeddin Sarvi Ahmad Daryani Mohammad Taghi Rahimi Mohsen Aarabi Azar Shokri Ehsan Ahmadpour Azadeh Mizani Mahdi Sharif | 2015 | Asian Pacific Journal of Tropical Medicine2015，8，2： | 4 |
| 3 | Role of hMLH1 and E-Cadherin Promoter Methylation in Gastric Cancer Progression显示文摘 | Meysam Moghbeli Omeed Moaven Bahram Memar Hamid Reza Raziei Azadeh Aarabi Ezzat Dadkhah Mohammad Mahdi Forghanifard Fatemeh Manzari Mohammad Reza Abbaszadegan | 2014 | Journal of Gastrointestinal Cancer2014，，1： | 2 |
| 4 | Seroprevalence of Toxoplasma gondii in the Iranian general population: A systematic review and meta-analysis显示文摘 | Ahmad Daryani Shahabeddin Sarvi Mohsen Aarabi Azadeh Mizani Ehsan Ahmadpour Azar Shokri Mohammad-Taghi Rahimi Mehdi Sharif | 2014 | Acta Tropica2014，，： | 2 |
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